• Title/Summary/Keyword: Magnetic capture

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Buffer-Optimized High Gradient Magnetic Separation: Target Cell Capture Efficiency is Predicted by Linear Bead-Capture Theory

  • Waseem, Shahid;Udomsangpetch, Rachanee;Bhakdi, Sebastian C.
    • Journal of Magnetics
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    • v.21 no.1
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    • pp.125-132
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    • 2016
  • High gradient magnetic separation (HGMS) is the most commonly used magnetic cell separation technique in biomedical science. However, parameters determining target cell capture efficiencies in HGMS are still not well understood. This limitation leads to loss of information and resources. The present study develops a bead-capture theory to predict capture efficiencies in HGMS. The theory is tested with CD3- and CD14-positive cells in combination with paramagnetic beads of different sizes and a generic immunomagnetic separation system. Data depict a linear relationship between normalized capture efficiency and the bead concentration. In addition, it is shown that key biological functions of target cells are not affected for all bead sizes and concentrations used. In summary, linear bead-capture theory predicts capture efficiency ($E_t$) in a highly significant manner.

Magnetic withdrawal of particles for multiple purposes in nuclear power plants

  • Kam, Dong Hoon;Jeong, Yong Hoon;Choi, Sung-Min;Yun, Jong-Il
    • Nuclear Engineering and Technology
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    • v.53 no.12
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    • pp.3979-3989
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    • 2021
  • Several parametric effects on the magnetic collection have been evaluated considering dimension, strength of external magnetic field, injected velocity and particle concentration in the working fluid. Besides, accidental environments, expected in the containment of nuclear power plants, have also been addressed for the capture efficiency. The capture efficiency is especially enhanced with magnetic particle size and magnetic field strength through increased magnetic force; the non-magnetic coating thickness and fluid velocity hinder the magnetic collection. Based on the assessment, the magnetic withdrawal system can effectively capture magnetic particles even under accidental environments. Withdrawal of multifunctional magnetic particles or filtering of magnetic impurities can be effectively realized through the system.

Study of Magnetic Filtration for Subway MVAC Dust (지하철 공조실 미세먼지에 대한 자성포집연구)

  • Park, Hae Woo;Chung, Sang Gui;Jo, Young Min
    • Particle and aerosol research
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    • v.11 no.2
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    • pp.37-46
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    • 2015
  • Dust particles, which inflow to the subway mechanical ventilation and air conditioning(MVAC) chamber, contain a fair amount of iron compounds, approximately 25.2w/w%. This work attempted to capture those iron containing dust using magnetic filters. Average magnetization value of the test MVAC dust was 0.012 emu on 5,000 Oe, which could correspond sufficiently with the magnetic interaction. External permanent magnets provided with magnetization of iron mesh screen showing high gradient magnetic field(HGM). It resulted in the capture efficiency with 84.0 ~ 99.7% and 81.2 ~ 99.8% for $PM_{10}$ and $PM_{2.5}$ respectively. Magnetic capture was found to be closely associated with the magnetic intensity, mesh opening size and flow velocity.

Theoretical Study on Magnetic Field Application for Fine Particle Capture

  • Huang, Shan;Park, Haewoo;Jo, Youngmin
    • Particle and aerosol research
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    • v.10 no.2
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    • pp.45-51
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    • 2014
  • Fine particle capture is facing a challenge since traditional filtration which relies on the combination of impaction, interception, diffusion has a limited efficiency for fine particle capture particularly in size from 0.1 to $0.5{\mu}m$. This paper reviewed the collection efficiency of above mechanisms, as well as magnetic mechanisms for ferromagnetic particles, and mainly studied the influencing factors of magnetic filtration. Filtration velocity, magnetic field intensity and fiber size were found to be the most important parameters for magnetic filtration.

A motion capture and mimic system (운동포착 및 재현 시스템)

  • 윤중선;최원수
    • 제어로봇시스템학회:학술대회논문집
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    • 1996.10b
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    • pp.1344-1347
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    • 1996
  • A general procedure for motion capture and mimic system has been delineated. Utilizing sensors operated in the magnetic fields, complex and optimized movements are easily digitized to analyze and follow. Design concepts of the system are modular, open, and user friendly to ensure the overall system performance. The system consists of motion capture, visualization, plan, mimic and GUI modules. This procedure is currently being implemented on a virtual cyber cube.

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Fine Iron Dust Collection by Magnetized Mesh Filters (철성분 미세먼지 포집을 위한 자성 필터 연구)

  • Park, Haewoo;Huang, Shan;Chung, Sang Gui;Kim, Sangbum;Jo, Young Min
    • Journal of Korean Society for Atmospheric Environment
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    • v.31 no.2
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    • pp.118-130
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    • 2015
  • Fine dust containing iron compounds is of current interests in metro subway as well as large scale industries including iron manufacturing and smelting works. This work attempts to find a new design of magnetic filter module for iron dust capture. It simulated the vertical rectangular duct with metal mesh which might promote electric fields in the duct space. A lab test using coal fly ash composed of 8.66% Fe with the most form of $Fe_3O_4$ and $Fe_2O_3$ showed capability of magnetic collection. It showed the capture efficiency with 80~93% for $PM_{2.5}$ depending on magnetic intensity. Ferromagnetic wire mesh contributed up to 50% of collection increment.

Magnetophoretic Microseparators for Separating Blood Cells Based on Their Native Magnetic Properties (혈액 세포의 고유자성을 이용한 마이크로 자기영동 세포분리기)

  • Jung, Jin-Hee;Han, Ki-Ho
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.32 no.11
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    • pp.856-862
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    • 2008
  • This paper presents the characterization of a continuous magnetophoretic microseparator for separating white and red blood cells from peripheral whole blood cells based on their native magnetic properties. The magnetophoretic microseparator separated the blood cells using a high gradient magnetic separation (HGMS) method without the use of additives such as magnetic beads or probing materials. Experimental results show that the paramagnetic capture mode microseparator can continuously separate out 93.5% of red blood cells and 97.4% of white blood cells from diluted whole blood, and the diamagnetic capture mode microseparator can continuously separate out 89.7% of red blood cells and 72.7 % of white blood cells by using applying an external magnetic flux of 0.2 T using a permanent magnet.

3-dimensional Coordinate Measurement by Pulse Magnetic Field Method (자기적 방법을 이용한 3차원 좌표 측정)

  • Im, Y.B.;Cho, Y.;Herr, H.B.;Son, D.
    • Journal of the Korean Magnetics Society
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    • v.12 no.6
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    • pp.206-211
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    • 2002
  • We have constructed a new kind of magnetic motion capture sensor based on the pulse magnetic field method. 3-orthogonal magnetic pulse fields were generated in turns only one period of sinusoidal waveform using 3-orthogonal magnetic dipole coils, ring counter and analog multiplier. These pulse magnetic fields were measured with 3-orthogonal search coils, of which induced voltages by the x-, y-, and l-dipole sources using S/H amplifier at the time position of maximum induced voltage. Using the developed motion capture sensor, we can measure position of sensor with uncertainty of ${\pm}$0.5% in the measuring range from ${\pm}$0.5 m to ${\pm}$1.5 m.

Distribution of Magnetic Field Depending on the Current in the μ-turn Coil to Capture Red Blood Cells (적혈구 포획용 미크론 크기 코일에 흐르는 전류의 크기에 따른 자기장 분포 특성)

  • Lee, Won-Hyung;Chung, Hyun-Jun;Kim, Nu-Ri;Park, Ji-Soo;Lee, Sang-Suk;Rhee, Jang-Roh
    • Journal of the Korean Magnetics Society
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    • v.25 no.5
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    • pp.162-168
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    • 2015
  • The ${\mu}$-turn coil having a width of ${\mu}m$ on the GMR-SV (giant magnetoresistance-spin valve) device based on the antiferromagnetic IrMn layer was fabricated by using the optical lithography process. In the case of GMR-SV film and GMR-SV device, the magnetoresistance ratios and the magnetic sensitivities are 4.4%, 2.0%/Oe and 1.6 %, 0.1%/Oe, respectively. In the y-z plane the distribution of magnetic field of GMR-SV device and $10{\mu}$-turns coil which put under the several magnetic bead(MB)s with a diameter of $1{\mu}m$ attached to RBC (red blood cell) was analyzed by the computer simulation using the finite element method. When the AC currents of 20 kHz from 0.1 mA to 10.0 mA flow to the 10 turns ${\mu}$-coil, the magnetic field at the position of $z=0{\mu}m$ at the center of coil was calculated from $30.1{\mu}T$ to $3060{\mu}T$ in proportion to the current. The magnetic field at the position of $z=10{\mu}m$ was decreased to one-sixth of that of $z=0{\mu}m$. It was confirmed that the $10{\mu}$-turn coil having enough magnitude of magnetic field for the capture of RBC is possible to use as a biosensor for the detection of magnetic beads attached to RBC.