• Journal of The Korean Society of Integrative Medicine
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• v.10 no.3
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• pp.85-94
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• 2022

Purpose : This study aimed to investigate the effects of 12 weeks of resistance exercise on body composition, physical strength, blood lipids, and insulin. Methods : The study was conducted on 24 elderly women divided into two groups: 12 subjects in an exercise group and 12 subjects in a control group. Resistance exercise was performed for 50 minutes a day, three times a week, for the duration of 12 weeks, and body composition, physical strength, blood lipids, and insulin were measured before and after the subjects completed the program. For the statistical analysis, the mean and standard deviation (M±SD) of each variable were calculated using SPSS version 20, and a paired t-test and two-way repeated ANOVA were conducted to test for the differences before and after the resistance exercise. All significant levels were set to α=.05 as a result of the experiment. Results : Changes in body composition after the 12-week resistance exercise program did not show any significant difference based on the comparison between the groups, but when noting the values for body fat percentage and body in the control group before and after, a significant difference was shown in fat mass (p<.05). As for changes in physical fitness, significant differences appeared in flexibility, muscle strength, and stenotic force (p<.01) when the groups were compared. Regarding pre- and post-values within each group concerning flexibility within the exercise group, significant differences were shown in gender (p<.001), muscle strength (p<.05), (p<.01), muscle earth strength, equilibrium (p<.01), stenosis force, and cardiopulmonary earth force (p<.001). Also, comparisons between populations in changes in blood lipids the values before and after in each group, significant differences in glucose (p<.05) and insulin (p<.05) were shown in the exercise group. When comparing the values before and after in each population, a significant difference was shown in the control group (p<.05). Conclusion : When all the results were integrated, the 12-week resistance exercise program was found to enhance physical strength (flexibility, muscle strength, and coordination) and improve the blood sugar levels of elderly women. In particular, resistance exercise is believed to lower the prevalence of obesity, type 2 diabetes mellitus, and metabolic diseases by having a positive effect on insulin. Further studies are suggested to verify the effect on body composition and blood lipids by setting up a variety of exercise treatment methods (including subjects, exercise periods, exercise plans, and exercise intensity focuses).

• Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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• 2001.06a
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• pp.1246-1246
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• 2001

The quality of meat is highly variable in many properties. This variability originates from both animal production and meat processing. At the pre-slaughter stage, animal factors such as breed, sex, age contribute to this variability. Environmental factors include feeding, rearing, transport and conditions just before slaughter (Hildrum et al., 1995). Meat can be presented in a variety of forms, each offering different opportunities for adulteration and contamination. This has imposed great pressure on the food manufacturing industry to guarantee the safety of meat. Tissue and muscle speciation of flesh foods, as well as speciation of animal derived by-products fed to all classes of domestic animals, are now perhaps the most important uncertainty which the food industry must resolve to allay consumer concern. Recently, there is a demand for rapid and low cost methods of direct quality measurements in both food and food ingredients (including high performance liquid chromatography (HPLC), thin layer chromatography (TLC), enzymatic and inmunological tests (e.g. ELISA test) and physical tests) to establish their authenticity and hence guarantee the quality of products manufactured for consumers (Holland et al., 1998). The use of Near Infrared Reflectance Spectroscopy (NIRS) for the rapid, precise and non-destructive analysis of a wide range of organic materials has been comprehensively documented (Osborne et at., 1993). Most of the established methods have involved the development of NIRS calibrations for the quantitative prediction of composition in meat (Ben-Gera and Norris, 1968; Lanza, 1983; Clark and Short, 1994). This was a rational strategy to pursue during the initial stages of its application, given the type of equipment available, the state of development of the emerging discipline of chemometrics and the overwhelming commercial interest in solving such problems (Downey, 1994). One of the advantages of NIRS technology is not only to assess chemical structures through the analysis of the molecular bonds in the near infrared spectrum, but also to build an optical model characteristic of the sample which behaves like the “finger print” of the sample. This opens the possibility of using spectra to determine complex attributes of organic structures, which are related to molecular chromophores, organoleptic scores and sensory characteristics (Hildrum et al., 1994, 1995; Park et al., 1998). In addition, the application of statistical packages like principal component or discriminant analysis provides the possibility to understand the optical properties of the sample and make a classification without the chemical information. The objectives of this present work were: (1) to examine two methods of sample presentation to the instrument (intact and minced) and (2) to explore the use of principal component analysis (PCA) and Soft Independent Modelling of class Analogy (SIMCA) to classify muscles by quality attributes. Seventy-eight (n: 78) beef muscles (m. longissimus dorsi) from Hereford breed of cattle were used. The samples were scanned in a NIRS monochromator instrument (NIR Systems 6500, Silver Spring, MD, USA) in reflectance mode (log 1/R). Both intact and minced presentation to the instrument were explored. Qualitative analysis of optical information through PCA and SIMCA analysis showed differences in muscles resulting from two different feeding systems.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.56 no.2
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• pp.204-211
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• 2023

This study investigated the physicochemical properties and palatability-enhancing effects of the alcohol precipitate, in the enzymatic extracts of Sargassum confusum C. Agardh (SC), obsained using the crude enzyme of Shewanella oneidensis PKA 1008. We analyzed the oligosaccharides recovered from the alcohol precipitate using a thin-layer chromatography for SC-degrading extracts, pH, color, reducing sugar, and viscosity. Thin-layer chromatography showed that after treating with the crude enzyme for 60 h, the polysaccharides were degraded into tetramers, dimers, and trimers and pH increased in the alcohol precipitate (EtOH Sedi). In terms of color, the redness and yellowness of alcohol precipitate/supernatant (EtOH Sedi+Super) and the brightness of EtOH Sedi were the highest among enzyme treated for 0 h and 60 h, EtOH Sedi, and EtOH Sedi+Super. In the reducing sugar analysis, EtOH Sedi showed the lowest value of 13.63 ㎍/mL, and the lowest viscosity of 1.13. In terms of the sensory evaluation, EtOH Sedi+Super showed the highest value with respect to the overall preference. These results suggest that the crude enzyme of S. oneidensis PKA 1008 is effective at degrading polysaccharides, and its recovery increases the palatability of the alcohol precipitate.

• The Journal of Korean Academy of Sensory Integration
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• v.20 no.3
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• pp.72-85
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• 2022

Objective : This study was conducted to examine self-selected goals and the outcome measures used in the Cognitive Orientation to daily Occupational Performance (CO-OP) approach for Developmental Coordination Disorder. Methods : Studies published from January 2012 to October 2022 in the PubMed, Embase, ScienceDirect, Cochrance Library databases were searched. Keywords used for search were ('developmental coordination disorder' OR 'DCD') AND ('Cognitive Orientation to daily Occupational Performance' OR 'Cognitive Orientation to Occupational Performance' OR 'CO-OP'). Among 211 searched studies, 7 selected studies that match the thesis of this study were analyzed. Results : The selected studies showed a relatively high level of evidence overall, including two randomized experimental studies, one non-random two-group study, three non-random one-group studies, one single-subject study. The self-selected goals preference of the children was high in the order of play, education, and daily life activities. Most of applicable sessions were conducted 10 times during a 1-h period, and intervention effects showed positive outcomes on the occupation performance motor domain. To measure the effectiveness of CO-OP, the improvement of occupational performance was evaluated using Canadian Occupational Performance Measure (COPM) and Performance Quality Rating Scale (PQRS), and the improvement of motor skills was evaluated using Movement Assessment Battery for Children (M-ABC). Conclusion : This study is expected to be used as basic clinical data when applying the CO-OP approach to Developmental Coordination Disorder.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.21 no.6
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• pp.87-96
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• 2022

The traffic vulnerable, including elderly pedestrians, have a relatively low walking speed and slow cognitive response time due to reduced physical ability. Although a smart crossing system has been developed and operated to improve problem, it is difficult to operate a signal that reflects the appropriate walking speed for each pedestrian. In this study, a neural network model and a multiple regression model-based traversing speed estimation model were developed using image information collected in an area with a high percentage of traffic vulnerability. to support the provision of optimal walking signals according to real-time traffic weakness. actual traffic data collected from the urban traffic network of Paju-si, Gyeonggi-do were used. The performance of the model was evaluated through seven selected indicators, including correlation coefficient and mean absolute error. The multiple linear regression model had a correlation coefficient of 0.652 and 0.182; the neural network model had a correlation coefficient of 0.823 and 0.105. The neural network model showed higher predictive power.

• Journal of Chest Surgery
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• v.56 no.3
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• pp.155-161
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• 2023

Background: Surgical closure of an atrial septal defect (ASD) is infrequently indicated during infancy. We evaluated the clinical characteristics and outcomes of patients who underwent surgical ASD closure during infancy. Methods: A single-center retrospective review was performed for 39 patients (19 males) who underwent surgical ASD closure during infancy between 1993 and 2020. The median body weight percentile at the time of operation was 9.3. Results: During a median follow-up of 60.9 months, 4 late deaths occurred due to chronic respiratory failure. A preoperative history of bronchopulmonary dysplasia (BPD) was the only risk factor for late mortality identified in Cox regression (hazard ratio, 3.54; 95% confidence interval [CI], 1.75-163.04; p=0.015). The 5-year survival rate was significantly lower in patients with preoperative history of BPD (97.0% vs. 50.0%, p<0.001) and preoperative ventilatory support (97.1% vs. 40.4%, p<0.001). There were significant postoperative increases in left ventricular end-diastolic (p=0.017), end-systolic (p=0.014), and stroke volume (p=0.013) indices. A generalized estimated equation model showed significantly better postoperative improvement in body weight percentiles in patients with lower weight percentiles at the time of operation (<10th percentile, p=0.01) and larger indexed ASD diameter (≥45 mm/m², p=0.025). Conclusion: Patients with ASD necessitating surgical closure during infancy are extremely small preoperatively and remain small even after surgical closure. However, postoperative somatic growth was more prominent in smaller patients with larger defects, which may be attributable to an increase in postoperative cardiac output due to changes in ventricular septal configuration. The benefits of ASD closure in patients with BPD are undetermined.

• Journal of Nutrition and Health
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• v.56 no.4
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• pp.391-403
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• 2023

Purpose: This study evaluated the validity of a physical activity classification table (PACT) based on total energy expenditure (TEE) and physical activity level (PAL) measured using the doubly labeled water (DLW) method in Korean adults and the elderly. Methods: A total of 141 (male 70, female 71) adults and elderly were included. The reference standards TEE_DLW, PAL_DLW were measured over a 14-day period using DLW. A 24-hour physical activity diary was kept for three days (two days during the week and one day on the weekend). PAL_PACT was calculated by classifying the activity type and intensity using the PACT. PAL_PACT was multiplied by resting energy expenditure measured by indirect calorimetry to estimate TEE_PACT. Results: The mean age of the study participants was 50.5 ± 18.8 years, and the mean body mass index was 23.4 ± 3.3 kg/m². A comparison of TEE_DLW and TEE_PACT by sex and age showed no significant differences. The bias, the difference between TEE_DLW and TEE_PACT, was male 17.3 kcal/day and female -4.5 kcal/day. The percentage of accurate predictions (values within ± 10% of the TEE_DLW) of TEE_PACT was 58.6% in males and 54.9% in females, with the highest prediction values in the age group 40-64 years (70.9%) in males and over 65 years (73.9%) in females. The spearman correlation coefficient (r) between TEE_PACT and TEE_DLW was 0.769, indicating a significant positive correlation (p < 0.001). Conclusion: In this study, the use of a new PACT for calculating TEE and PAL was evaluated as valid. A web version of the software program and a smartphone application need to be developed using PACT to make it easier to apply for research purposes.

• Korean Journal of Culture and Social Issue
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• v.17 no.4
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• pp.415-434
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• 2011

Leisure is an important role on happiness and health in midlife. Nevertheless, there has been little research using a longitudinal method in Korea to identify the influence of leisure on happiness and health. Current study examined the effect of leisure satisfaction and time for leisure activities on happiness(SHS) and health-related variables(psychological symptoms, physical symptoms, and quality of sleep) in middle aged adults(40-65 years) by longitudinal data. Two surveys were conducted with 10 months' interval and total 145 respondents(M=49.45) participated in both surveys. Hierarchical regression analysis was employed to investigate that both leisure satisfaction and time for leisure activities in the first time have an effect on happiness and health-related variables in the second time after controlling for each happiness and health variables in the first time as well as demographic variables. We found that leisure satisfaction influenced beneficially on happiness(SHS), psychological symptoms, and quality of sleep after 10-month. Similarly, time for leisure activities had effect on happiness(SHS), psychological symptoms, and physical symptoms after 10-month. The implication for study were discussed.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.9 no.1
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• pp.17-21
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• 2023

In this study, we evaluated the targeting of prostate cancer (PCa) using [¹⁸F]Florastamin in non-clinical study, for the purpose of therapeutic monitoring of [¹⁷⁷Lu]Ludotadipep, a therapeutic radiopharmaceutical for PCa, [¹⁸F]Florastamin/[¹⁷⁷Lu]Ludotadipep was co-administered to a single-individual prostate tumor bearing mouse model, mimicking clinical condition. Considering the difference in half-life of the two isotopes (¹⁸F or ¹⁷⁷Lu), image scan of whole-body autoradiography was performed at 24 or 48 h after preparation of frozen section, respectively. Then, it was confirmed whether they showed the same targeting efficiency for the area of tumor. A tumor xenograft model was prepared using PSMA-overexpressing PC3-PIP prostate cancer cells. [¹⁸F]Florastamin [111 MBq (3 mCi) in 100 µL]/¹⁷⁷Lu]Ludotadipep [3.7 MBq (100 µCi) in 100 µL] was co-administered through the tail vein, and 2 hours after administration, the mice were frozen, and after freezing for 24 hours, whole-body cryosection was performed at 24 h after freezing. Image scanning using cryosection was performed after 24 or 48 hours after freezing, respectively. In the scan image after 24 hours, tumor uptake of [¹⁸F] Florastamin/[¹⁷⁷Lu]Ludotadipep were simultaneously observed specific uptake in the tumor. In the scan image after 48 hours in the same section, signal of ¹⁸F was lost by decay of radioisotope, and specific uptake image for [¹⁷⁷Lu]Ludotadipep was observed in the tumor. Uptake of [¹⁷⁷Lu]Ludotadipep was specific to the same tumor region where [¹⁸F]Florastamin/[¹⁷⁷Lu]Ludotadipep was uptake. These results suggested that [¹⁸F]Florastamin showed the same tumor uptake efficiency to PCa as [¹⁷⁷Lu]Ludotadipep, and effective therapeutic monitoring is expected to be enable using [¹⁸F]Florastamin during [¹⁷⁷Lu]Ludotadipep therapy for PCa.

• Journal of Practical Agriculture & Fisheries Research
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• v.15 no.1
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• pp.183-202
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• 2013

The demand of ginseng which has attracted many people for a long time has expanded further with great spotlight ; but it has caused anxiety of some safety-sensitive customers due to unavoidable pesticides and its weakness for disease and insect pest. On the other hand, sluggish studies on effective doses of ginseng and red ginseng which is produced and processed after hardship have worsened confusion of customers. Against this backdrop, this study is about to find out measures for safe ginseng cultivation and effective dose of white or red ginseng which are safely produced and reaches meaningful conclusions as follows ; As for a study to minimize the use of chemical fertilizers and pesticides or to change them into environmentally-friendly products, ginseng cultivation utilizing Lime Sulfur complex might be an alternative. The effects of Lime Sulfur complex are great on ginseng seeding with under 200 times compound KHCO3 and five-year-old ginseng with over 200 times compound using NaHCO3. When using with green materials like Bordeaux mixture, there would be great potential to realize ginseng without pesticide use.