• The Transactions of The Korean Institute of Electrical Engineers
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• v.67 no.7
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• pp.910-916
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• 2018

In this paper, we developed a shoulder rehabilitation exercise device and monitoring system to remotely provide rehabilitation system for the ones who need shoulder exercises including the patients with rotator cuff rupture. In order to evaluate the severity of shoulder muscle injury, a total of 4 shoulder rehabilitation exercises ((3) shoulder abduction, (2) shoulder flexion, (3) shoulder abduction with elbow flexion, (4) shoulder extension with elbow flexion) were selected and instructed to be performed with a 3 kg dumbbell for 5 times. For EMG (electromyogram) signal analysis, each subject's maximum voluntary contraction (MVC) was measured. EMG signals reflect the activation level of contracting muscles during dynamic exercises. Six participants' muscle activation levels in posterior deltoid, middle deltoid, upper trapezius, and infraspinatus were measured and compared. The mean power spectrum values in the time and frequency domains were compared between two age-matched groups (20s and 50s). The results showed lower muscle activation in the elderly subjects (n=3) compared to that of the ones in their twenties (n=3).

• Molecules and Cells
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• v.28 no.6
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• pp.589-593
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• 2009

In this study, the roles of the p38 MAPK, ERK1/2 and JNK signaling pathway in IGF-I-induced AR induction and activation were examined. C2C12 cells were treated with IGF-I in the absence or presence of various inhibitors of p38 MAPK (SB203580), ERK1/2 (PD98059), and JNK (SP600125). Inhibition of the MAPK pathway with SB203580, PD98059, or SP600125 significantly decreased IGF-I-induced AR phosphorylation and total AR protein expression. IGF-I-induced nuclear fraction of total AR and phosphorylated AR were significantly inhibited by SB203580, PD98059, or SP600125. Furthermore, IGF-I-induced AR mRNA and skeletal ${\alpha}-actin$ mRNA were blocked by those inhibitors in dose-dependent manner. Confocal images showed that IGF-I-induced AR nuclear translocation from cytosol was significantly blocked by SB203580, PD98059, or SP600125, suggesting that the MAPK pathway regulates IGF-I-induced AR nuclear localization in skeletal muscle cells. The present results suggest that the MAPK pathways are required for the ligand-independent activation of AR by IGF-I in C2C12 skeletal muscle cells.

• The Korean Journal of Physiology and Pharmacology
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• v.14 no.5
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• pp.299-304
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• 2010

Losartan is a selective angiotensin II (Ang II) type 1 ($AT_1$) receptor antagonist which inhibits vascular smooth muscle cells (VSMCs) contraction and proliferation. We hypothesized that losartan may prevent cell proliferation by activating AMP-activated protein kinase (AMPK) in VSMCs. VSMCs were treated with various concentrations of losartan. AMPK activation was measured by Western blot analysis and cell proliferation was measured by MTT assay and flowcytometry. Losartan dose- and time-dependently increased the phosphorylation of AMPK and its downstream target, acetyl-CoA carboxylase (ACC) in VSMCs. Losartan also significantly decreased the Ang II- or 15% FBS-induced VSMC proliferation by inhibiting the expression of cell cycle associated proteins, such as p-Rb, cyclin D, and cyclin E. Compound C, a specific inhibitor of AMPK, or AMPK siRNA blocked the losartan-induced inhibition of cell proliferation and the $G_0/G_1$ cell cycle arrest. These data suggest that losartan-induced AMPK activation might attenuate Ang II-induced VSMC proliferation through the inhibition of cell cycle progression.

• Korean Journal of Applied Biomechanics
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• v.23 no.2
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• pp.141-148
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• 2013

The purpose of this study was to investigate the scapulothoracic joint movement between different weight bearing contributing to effective bench press exercise. Ten male subjects participated in this study. All subjects were tested on the flat bench press machine which modified weight (50% and 70% of 1RM) and subjects were performed two different conditions(none protraction condition and protraction condition). Weight bar height and vertical velocity, EMG activation was measured using 3D motion capture system and wireless EMG analysis system. As the results, none protraction condition showed that it is more concentrate better pectoralis major muscle activation than protraction condition and middle pectoralis major, anterior deltoid and triceps brachii was significant higher integrated EMG in 70% of 1RM condition. In conclusion, limited scapulothoracic joint movement was more effective activated pectoralis major muscle all the weight through, while we could not find that it was not affected integrated EMG on eight muslces related to shoulder complex between scapulothracic joint movement conditions.

• The Journal of Korea Robotics Society
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• v.19 no.2
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• pp.203-212
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• 2024

Simultaneous motion is essential in the activities of daily living (ADL). For motion intention recognition, surface electromyogram (sEMG) and corresponding motion label is necessary. However, this process is time-consuming and it may increase the burden of the user. Therefore, we propose a simultaneous motion recognition framework using data augmentation based on muscle activation model. The model consists of multiple point sources to be optimized while the number of point sources and their initial parameters are automatically determined. From the experimental results, it is shown that the framework has generated the data which are similar to the real one. This aspect is quantified with the following two metrics: structural similarity index measure (SSIM) and mean squared error (MSE). Furthermore, with k-nearest neighbor (k-NN) or support vector machine (SVM), the classification accuracy is also enhanced with the proposed framework. From these results, it can be concluded that the generalization property of the training data is enhanced and the classification accuracy is increased accordingly. We expect that this framework reduces the burden of the user from the excessive and time-consuming data acquisition.

• Journal of the Korean Society of Physical Medicine
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• v.5 no.3
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• pp.405-412
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• 2010

Purpose : The purpose of this study was to assess the effects of the trunk muscle activity on bridging exercise according to the knee joint angle. Methods : Twenty-five healthy adults volunteered to participate in this study. Subjects were required to complete following four bridging exercises; knee joint flexion $120^{\circ}$, $90^{\circ}$, $60^{\circ}$, $45^{\circ}$. Surface electromyography from selected trunk muscles was normalized to maximum voluntary isometric contraction. Muscle activity was measured by QEMG-4 system(LXM 3204, Laxtha Korea). A repeated measures of one-way ANOVA with post-hoc Bonferroni's correction was used to determine the influence of bridging exercise on muscle activity for each muscle and descriptive statistics was used to determine local/global muscle ratio. Results : The internal oblique of bridging exercises $120^{\circ}$, $90^{\circ}$ showed significantly(p<.05). The erctor spinae of all bridging exercises showed significant excepted between $60^{\circ}$ and $45^{\circ}$(p<.05). Median of internal oblique/rectus abdominis ratio of $120^{\circ}$ was 4.41, $90^{\circ}$ was 3.94, $60^{\circ}$ was 3.58, $45^{\circ}$ was 3.39. Median of internal oblique/external oblique ratio of $120^{\circ}$ was 2.66, $90^{\circ}$ was 2.43, $60^{\circ}$ was 2.87, $45^{\circ}$ was 2.64. Conclusion : Angular motion decreasing with knee joint flexion made erector spinae activation increase. on the other hand, as decreasing abdomen muscle activation, the more performing motor learning is required for abdomen muscle strength and co-contraction for the trunk stabilization.

• Physical Therapy Rehabilitation Science
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• v.9 no.2
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• pp.113-119
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• 2020

Objective: The vibration device is one of the most commonly used warm-up devices not only for healthy athletes but also for healthy individuals. Therefore, this study aimed to investigate the immediate effects of local vibration on ankle plantar flexor muscle activation and peak torque in healthy adults. Design: One-group pretest-posttest design. Methods: This was a single-group study comprising a total of 36 (16 males and 20 females) participants. The average age of the 36 participants was 22.3 years. All the participants' concentric and eccentric peak torques of the gastrocnemius lateralis muscle were measured using an isokinetic device. Simultaneously, the participants' muscle activity was measured by surface electromyography. After the pre-experimental data were collected, the participants comfortably sat on the prepared chair with their hips and knees flexed to 90°. While in sitting position, local vibration was applied for 10 minutes using a 1:1 ratio intermittent pulsing mode device based on a previous study. Then, the post-experimental data were collected immediately after the local vibration by performing a similar process performed during the pre-experimental data collection. Results: The results showed a significant difference in muscle activity and eccentric peak torque (p<0.05). On the contrary, concentric peak torque values showed an insignificant difference with pre- and post-value. Conclusions: The results of this study demonstrated that local vibration can be possibly considered as one of the effective ways to increase ankle plantar flexor muscle activity and muscle performance, specifically the eccentric peak torque, in healthy adults.

• Physical Therapy Rehabilitation Science
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• v.10 no.3
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• pp.244-250
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• 2021

Objective: The purpose of this study was to investigate the effect of sprinter pattern bridging exercise using theraband on activation of lower extremity and abdominal muscle and to find out postures that can effectively improve abdominal and lower extremity muscle strength and increase abdominal stability. Methods: This study was designed as a cross-sectional study. The following research was done with applicants attending S university in Seoul to compare the difference in muscle activity between one-leg-Support bridging exercise and sprinter-pattern bridging exercise using theraband. For 48 study participants, we first measured their MVC. Then, we applied one-leg-support bridging exercise and sprinter-pattern bridging exercise at random order. These data were expressed as the percentage of maximal voluntary contraction (%MVC).Electromyography analysis was performed by measuring the external obliques, internal obliques, biceps femoris, and gluteus maximus. Results: There was a statistically significant increment of muscle activity in external and internal oblique muscle(p<0.001)by sprinter-pattern bridging exercise using theraband. On the lower body, statistically significant increment of muscle activity in biceps femoris and gluteus maximus was found(p<0.05). On the other hand, on erector spinae, there was statistically significant decrease in muscle activity(p<0.05). Conclusions: Efficient treatment is expected when sprinter-pattern bridging exercise using theraband is applied clinically.For patients with chronic knee and ankle pain who have difficulty bearing weight, including low back pain and internal rotation of the femur, starting with a low weight bearing, we think it will be helpful in planning systematic training aimed at progressively strengthening the lower extremities.

• Physical Therapy Korea
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• v.19 no.2
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• pp.1-11
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• 2012

The pelvic compression belt (PCB) contributes to improving sacroiliac joint stability, and it has been used as an additional therapeutic option for patients with sacroiliac joint pain (SIJP). This study aimed to investigate whether the muscle activation patterns of the supporting leg was different between asymptomatic subjects and subjects with SIJP during one-leg standing, and how it changes with the PCB. 15 subjects with SIJP and 10 asymptomatic subjects volunteered to participate in this study. Surface electromyography (EMG) data (reaction time [RT] and muscle activation) were collected from the internal oblique, lumbar multifidius, gluteus maximus and biceps femoris muscles during one-leg standing with and without the PCB. Without the PCB condition, in the SIJP group, the biceps femoris muscle showed the fastest RT among all muscles (p<.05), whereas in the asymptomatic group, the RT of the internal oblique muscle was the most rapid (p<.05). In condition without the PCB, the biceps femoris EMG amplitudes in the SIJP group were significantly greater than that in the asymptomatic group (p<.05). After the application of the PCB, the RT of the biceps femoris muscle was significantly increased only in the SIJP group (p<.05). Moreover, the biceps femoris EMG amplitudes significantly decreased and the gluteus maximus EMG amplitudes significant increased only in the SIJP group by applying the PCB (p<.05). However, this had no such effect on the gluteus maximus and biceps femoris EMG patterns in the asymptomatic group (p>.05). Thus, this study supports the applying the PCB to patients with SIJP can be used as a helpful option to modify the activation patterns of the gluteus maximus and biceps femoris muscle.

• Physical Therapy Korea
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• v.16 no.2
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• pp.1-8
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• 2009

Anticipatory postural adjustments is an example of the ability of the central nervous system to predict the consequence of the mechanical effect of movement on posture and helps minimize a forth coming disturbance. The aim of this study was to evaluate the sequence of activation of the trunk muscles during the performance of hip and shoulder movement and to determine the relationship between anticipatory activity and subjects' motor and functional status in subjects with hemiplegia post stroke. Twenty-four poststroke hemiparetic patients enrolled in this study. Electromyographic activity of the lumbar erector spinae, latissimus dorsi, and of the obliquus internus muscles was recorded bilaterally during flexion of both arm and from the rectus abdominis, obliquus externus, and obliquus internus muscles during flexion of both hip. Onset latencies of trunk muscles were partially delayed in the subjects with hemiplegia post stroke (p<.05). With upper limb flexion, the onset of erector spinae muscle and latissimus dorsi muscle activity preceded the onset of deltoid on both side respectively (p<.05). A similar sequence of activation occurred with lower limb flexion. Also the onset of external oblique muscle and rectus abdominis muscle activity preceded the onset of rectus femoris muscle on both side (p<.05). Major impairments in the activity of trunk muscles in hemiparetic subjects were manifested in delayed onset between activation of pertinent muscular pairs. These problems were associated with motor and functional deficits and warrant specific consideration during physical rehabilitation of post stroke hemiparetic patients.