• Journal of the Korean Chemical Society
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• v.67 no.2
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• pp.99-105
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• 2023

Here we present how a supramolecular complex of Glycyrrhizic acid (GA) with Menthol (Mt) affects the blood glucose levels and glycogen synthesis in the liver of rats in in-vivo experiments with diabetes caused by alloxan. We have shown that Menthol, Glycyrrhizic acid and GA:Mt supramolecular complexes can restore functional dysfunction of the liver mitochondria in alloxan diabetes, i.e., inhibit lipid peroxidation. The hypoglycemic activity and mitochondrial membrane stabilizing properties of the supramolecular complex GA:Mt (4:1) in alloxan diabetes were more pronounced than those of menthol, GA and its GA:Mt (2:1) and GA: Mt (9:1) supramolecular complexes.

• Geophysics and Geophysical Exploration
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• v.27 no.2
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• pp.129-143
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• 2024

In magnetotelluric (MT) surveys, small inhomogeneities near the surface cause a static shift in which apparent resistivities shift regardless of frequency. As the static shift in MT data leads to errors in subsurface structure interpretation, many studies have been conducted over the past few decades to mitigate or remove the distortions it caused. The most representative method involves removing static shifts from the data before inversion. Conversely, static shifts can be corrected during inversion or included in the inversion process. In addition, other geophysical data can be used to remove static shifts. However, the correction methods are limited to one-dimensional (1D) static responses, and limitations remain in two- or three-dimensional (2D or 3D) interpretation of distorted MT data owing to static shifts. This study provides a foundation for future studies on static shift by analyzing several previously published methods.

• Journal of the Korean Geographical Society
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• v.51 no.1
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• pp.127-142
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• 2016

This paper analyzes on the physical place name of Mt. Seoraksan in Joseon period from the historical geographical perspective. The analysis materials are Jirijis, old maps and travel records of Joseon period. The results are as follows. The space range of Mt. Seoraksan in Joseon period and today was different. Mt. Seoraksan in Joseon period was around Daecheongbong Peak nowadays, Ulsanbawi Rock was Mt. Cheonhusan, and north mountain range of Hangyeryeong Pass called Mt. Hangyesan. Region of Mt. Seoraksan and Mt. Hangyesan were devided in Joseon Period. Mt. Seoraksan name was representative in late Joseon period including Mt. Hangyesan and Mt. Cheonhusan. Mountain names were the most in the physical place name. The old name of Hangyeryeong Pass was Osaek Pass in maps of Joseon Period. The popular travel course of Mt. Seoraksan in Joseon period was Baekdamsa Temple-Oseam Temple-Sinheungsa Temple.

• Archives of Pharmacal Research
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• v.20 no.6
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• pp.560-565
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• 1997

The physicochemical properties of melatonin (MT) in propylene glycol (PG) and 2-hydroxypropyl-.betha.-cyclodextrin $(2-HP{\beta}CD)$ vehicles were characterized. MT was endothermally decomposed as determined by differential scanning calorimetry (DSC). Melting point and heat of fusion obtained were $116.9{\pm}0.24^{\circ}C $.and $7249{\pm}217 cal/mol$., respectively. MT as received from a manufacture was very pure, at least 99.9%. The solubility of MT in PG solution increased slowly until reaching 40% PG and then steeply increased. Solubility of MT increased linearly as concentration of $2-HP{\beta}CD$ without PG INCREASED$(R^2=0.993)$. MT solubility in the mixtures of pg and $2-HP{\beta}CD$ also increased linearly but was less than the sum of its solubility in $2-HP{\beta}CD$ and PG individually. The MT solubility was low in water, simulated gastric or intestinal fluid but the highest in the mixture of PG(40v/v%) and $2-HP{\beta}CD$ (30w/v%) although efficiency of MT solubilization in $2-HP{\beta}CD$ decreased as the concentration of PG increased. MT was degraded in a fashion of the first order kinetics $(r^2>0.90)$. MT was unstable in strong acidic solution (HCl-NaCl buffer, pH 1.4) but relatively stable in other pH values of 4-10 at $70^{\circ}C$. In HCl-NaCl buffer, MT in 10% PG was more quickly degraded and then slowed dpwm at a higher concentration. However, the degradation rate constant of MT in 2-HP.betha.CD was not changed significantly when compared to the water. The current studies can be applied to the dosage formulations for the purpose of enhancing percutaneous absorption or bioavailability of MT.

• Korean Journal of Soil Science and Fertilizer
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• v.47 no.1
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• pp.8-15
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• 2014

In order to evaluating physiochemical properties of soil under minimum tillage and direct seeding cultivation on dry rice paddy, we conducted to analyze the soil physiochemical characteristics in treatment with 2-year minimum tillage and dry direct seeding (2MT), 3-year minimum tillage and dry direct seeding (3MT), and tillage transplanting cultivation (TT). As results of analyzing soil organic matter (OM) contents with 2 cm soil depth of interval from surface to 30 cm, OM contents with surface soil from 0 to 2MT and 3MT were higher than TT, recorded 34.6, 28.1 and $19.8gkg^{-1}$, respectively. But until 20cm in soil depth, it was not so large on the deviation of OM contents among the 3 treatments comparing with 2cm surface. Beneath 20 cm in soil depths, 2- and 3-year, OM contents in TT were distributed to be lower than 2MT and 3MT. The contents of total nitrogen in 2MT and 3MT were higher than the content in TT across the soil profile. Consequently, though minimum tillage and direct seeding farming is obviously the practice to saving of machinery work and labor, other practices such as continuously input OM should be needed to achieve carbon sequestration goal through minimum tillage and direct seeding on dry paddy.

• Journal of Aquaculture
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• v.9 no.3
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• pp.279-285
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• 1996

The effects of various concentrations of $17{\beta}-methyltestosterone$ (MT) or $17{\beta}-estradiol\;(E_2)$ on sex reversal, survival and growth rates of olive flounder, Paralichthys olivaceus were investigated. MT and $E_2$ were treated to juvenile flounder for 60 days from 30 (total length : 14.5 mm) to 90 (TL : $10.41\~11.17$ mm) days after hatching. Fish were treated with 0, 1, 10 and 100 ppb of MT or $E_2$ in the rearing water for 2 hours per day. At the time of 200 days after hatching, fish were sampled to examine sex ratio. One hundred pub of MT produced $100\%$ male, however 1 and 10 ppm MT produced 72.5 and $87.2\%$ males. One, 10 and 100 ppb of $E_2$ produced 75.5, 91.9 and $97.2\%$ females, respectively. Survival and growth rates of each experimental group at the end treatment were not significantly different from those of the control (P>0.05).

• Journal of Plant Biotechnology
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• v.42 no.2
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• pp.93-103
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• 2015

The isolation, cloning, and characterization of an R2R3-MYB transcription factor gene (MtMYB70) from the model legume Medicago truncatula is reported. MtMYB70 consists of a 768-bp coding sequence corresponding to 255 amino acids. Sequence alignment revealed that MtMYB70 cDNA contains conserved R2R3-type MYB domains with highly divergent C terminal regions. MtMYB70 was found to have relatively low sequence homology with known R2R3-MYB genes. Phylogenetic analysis placed the R2R3-MYB domain of MtMYB70 closest to PtMYB1, a known activator of lignin biosynthesis. Overexpression of MtMYB70 under the control of the 35S promoter in transgenic poplar did not cause a significant difference in total lignin content relative to the control, but glucan content was significantly increased in transgenic poplar. Therefore, MtMYB70 might have regulatory role in the biosynthesis of cell wall structural carbohydrates.

• Korean Journal of Environment and Ecology
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• v.22 no.3
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• pp.221-229
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• 2008

This study observed and compared phenological changes in the spring for some native woody plants growing at Mt. Jumbong and Mt. Bongeui located at central districts of our country, and also inquired into the phenological difference subsequent to microclimate change by measuring its related environment factors as well. The average air temperature at a survey point of Mt. Jumbong from January to May in 2004 was $4.1^{\circ}C$ lower than that of Mt. Bongeui. As for the soil temperature in April by a survey section within Mt. Jumbong, the soil temperature on the west and northwest slopes was $1.8^{\circ}C$ and $4.4^{\circ}C$ lower than that of the south slope, respectively. It was found that the earliest tree species in a flowering period was Lindera obtusiloba among the sample woody plants and its flowering began in late March at Mt. Bongeui and in early April at Mt. Jumbong. The flowering of the same species began faster on the south slope than the west or north slope; in case of the tree species flowering in early spring, there appeared about two-week interval between the survey sites. Likewise, leafing time of the same species was two weeks earlier at Mt. Bongeui(in mid-April) than at Mt. Jumbong(in early May). Nuttonson's Index and Year Day Index for the flowering and leafing time of the same species showed similar value between the survey sites. It is analyzed that the transition in phenological phases between the sites is mainly caused by temperatures; further, it is implied that the climate changes and rise in temperatures could expedite the changes in phenological phases more than ever.

• The Korean Journal of Physiology and Pharmacology
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• v.25 no.1
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• pp.39-49
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• 2021

High fructose diet is associated with the global metabolic syndrome (MtS) pandemic. MtS develops in early life, depending on prenatal and postnatal nutritional status. We hypothesized that ovariectomy increases the chances of developing MtS in adult offspring following high fructose intake by the mother. Pregnant C57BL/6J mouse dams drank water with or without 20% fructose during pregnancy and lactation. After weaning, the pups were fed regular chow. The offspring were evaluated until they were 7 months of age after the mice in each group, both sexes, were gonadectomized at 4 weeks of age. The offspring (both sexes) of the dams who had high fructose intake developed MtS. In the offspring of dams who drank tap water, orchiectomy increased the body weight gain and body fat accumulation, while ovariectomy increased the body fat accumulation as compared to the sham controls. In the offspring of dams with high fructose intake, orchiectomy decreased the body weight gain, body fat accumulation, visceral adiposity, and glucose intolerance, while ovariectomy exacerbated all of them as compared to the sham operations. These data indicate that ovariectomy encourages the development of MtS in adult offspring after maternal high fructose intake, while orchiectomy prevents the development of MtS. The sex difference indicates that male and female sex hormones play contradictory roles in the development of MtS.

• Fisheries and Aquatic Sciences
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• v.5 no.1
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• pp.59-63
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• 2002

Swim up fry of the Nile tilapia, Oreochromis niloticus, were fed 0 or 60 mg l7-methyltestos­terone (MT) per kg feed for 30 days. Fish that had been fed 0 or 60 ppm MT for the first 30 days were subsequently fed a commercial diet for 56 weeks to evaluate growth, survival, sex ratio, body composition, gonadosomatic index and the total edible portion. Mean body weight of MT treated group and untreated group were 1.7 g and 1.1 g, respectively at the end of the treatment for 30 days $(P<0.05)$. The experiment was terminated after a total of 60 weeks, the mean body weight of the MT treated population was 1,016 g and that of the untreated population was 762g $(P<0.05)$. However, the final mean body weight of untreated males (l, 086g) was not significantly different from treated males (l,016 g), but the mean body weight of the female group was 512 g. Therefore, the reason for the lower mean body weight of the untreated group was entirely due to stunted females. The percentage fillet yield of MT treated fish$(34.6\%)$ was not significantly different from that of the untreated males $(34.4\%)$, but the untreated females were lower than those of both treated and untreated male groups $(32.4\%)$ (P<0.05). There were no significant differences in the percentage of the all edible portion (AP) between MT treated and untreated males, but females were lower than males. Females are smaller fish in size and the gonads are larger in proportion which were discarded along with the intestine this explains the observed difference. Total biomass of the two groups were 134.8kg and 104.5kg per $m^3$, respectively. The proportion of fish reaching a marketable size of over 800 g in body weight within 14 months were $78\%$ in the MT treated group and $41\%$ in the untreated group.