• Title/Summary/Keyword: MSK1

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Plant Regeneration from Shoot Tip-Derived Embryogenic Callus of Dianthus superbus

  • Lee, Eun-Ae;Kim, Joon-Chul;Kim, Won-Bae;Kim, Byeong-Hyeon;Kim, Jeong-Kan
    • Journal of Plant Biology
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    • v.37 no.3
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    • pp.381-385
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    • 1994
  • The highest degree of callus formation was obtained from the shoot tips of Dianthus superbus when cultured on the MS medium supplemented with 2.0 mg/L NAA and 0.5 mg/L BAP. Embryogenic calluses were obtained from the seperated friable calluses on MS medium containing 2.0 mg/L 2,4-D after 7-8 wk of culture. For plant regeneration, embryogenic calluses were selected and cultured on te proliferation medium. After 3 wk, somatic embryos appeared on MSK medium (0.5 mg/L NAA, 2.0 mg/L kinetin) and N6 medium (2.0 mg/L kinetin, 0.1 mg/LNAA, 0.1 mg/L 2,4-D and 2.0 g/L casein hydrolysate). When these somatic embryos were kept under continuous illumination, shoots were successfully regenerated on the both media. The shoots were rooted on MS medium supplemented with 2.0 mg/L NAA.

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Performance Comparison for MODEM in MUltipath Fading Channel (다중경로 페이딩 채널에서의 변복조 성능비교)

  • 전동근;박형근;이연우
    • The Journal of the Acoustical Society of Korea
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    • v.17 no.4
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    • pp.28-34
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    • 1998
  • 미래 개인 휴대통신에서는 고속의 데이터 서비스를 위하여 높은 대역폭 효율을 요 구하게 된다. 무선통신 서비스를 향상시키기 위하여 코딩기법, 변조기법, 다중화기법 등의 다양한 방법이 연구되고 있다. 이중에서 특히 변조기법은 시스템의 성능을 결정하는 중요한 요소가 된다. 본 논문에서는 PSK. OQPSK, π/4 DQPSK, MSK, GMSK의 다섯가지 변조기 법에대한 BER성능을 시뮬레이션하였다. 시뮬레이션을 위한 다중경로 페이딩채널로서 3가지 서로 다른 채널을 적용하였다. 이때 시뮬레이션을 위하여 1.544Mbps의 전송속도와 1.9GHz 의 반성주파수 환경을 고려하였다. 또한 fractional 선형 등화기를 적용하여 변조방식에 따른 성능향상 정도를 비교하였다. 채널 Ⅰ, Ⅱ, Ⅲ에 대해 각각 30dB, 20dB, 10dB 정도에서 error floor현상이 발생했으며 π/4 DQPSKS가 가장 낮은 BER 특성을 보인 반면 QPSK는 가장 높은 BER을 나타냈다. 등화기를 적용했을 때는 GMSK의 성능향상이 가장 크게 나타 났다.

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OQ2PSK Modulation with Overlapped Raised-Cosine Pulse Shaping (중첩 상승여현 펄스 정형 OQ2PSK 변조)

  • Jeon, Sang Yeop;Chung, Jae-Kyung;Kim, Myoung Jin
    • Journal of the Institute of Electronics and Information Engineers
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    • v.52 no.1
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    • pp.7-16
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    • 2015
  • The transmitter of quadrature multiplexed GMSK (QM-GMSK) is composed of two quadrature multiplexed GMSK modulators. QM-GMSK has a slightly increased spectrum main lobe compared with $Q^2PSK$ or QMSK, but it has highly suppressed side lobes. As a result, practical spectrum efficiency of QM-GMSK is achieved. By replacing the baseband elementary pulses of QM-GMSK with their approximate, the squared sinusoid of half-period, offset-$Q^2PSK$($OQ^2PSK$) is obtained. The $OQ^2PSK$ signal has similar spectral properties to QM-GMSK. The transmitter of $OQ^2PSK$ can be simply implemented without the Gaussian lowpass filter, which is required in QM-GMSK transmitter. In this paper, we propose an overlapped pulse shaping in $OQ^2PSK$ with RC(raised-cosine) or SRC(squared raised-cosine) pulses of length longer than the symbol period. Power spectrum of the proposed modulation scheme exhibits further suppressed side lobes, hence enhanced spectrum efficiency is obtained. Simulation results indicate that BER performance of the proposed scheme is comparable to that of $OQ^2PSK$.

Neuropharmacological study of some Ayurvedic medicinal plants

  • Hannan, JMA;Shahriar, Masum;Islam, M Naimul;Sattar, Mafruhi;Haque, Sabera;Choudhuri, MSK
    • Advances in Traditional Medicine
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    • v.3 no.1
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    • pp.8-17
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    • 2003
  • Water extract (kwath) of six different widely used Ayurvedic medicinal plants were tested in mice for possible neuropharmacological efficacy. In the present experiments it was observed that a number of plant tested causes a significant level of Central Nervous System (CNS) depression, in that it significantly decreased the spontaneous Motor activity, and also lowered the exploratory behavior of the treated animals. Terminalia chebula (HAA), Terminalia bellerica (BHA), Emblica officinalis (AA), Piper longum 1. (PP). exhibited depressant action of on the CNS. Apart from them a mild to moderate degree of depression was evident as a consequence of administration of Zingiber officinale Rosc (SUT), Piper nigrum L. (MRC). However, none of the plant tested did not exhibit significant effects on pentobarbital induced narcosis, and this indicated that the sedating effects of the drug was not associated with the risk of fatal consequences on overdose.

Pharmacological study of 'treenoponchomul'-an Ayurvedic diuretic preparation

  • Haque, Sabera;Hannan, JMA;Shahriar, Masum;Islam, M Naimul;Sattar, Mafruhi;Choudhuri, MSK
    • Advances in Traditional Medicine
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    • v.3 no.1
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    • pp.21-28
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    • 2003
  • The pharmacological effects of an Ayurvedic diuretic drug 'Treenoponchomul' (TPM) was investigated in animal model. The pharmacological actions of the test drug along with that of the components thereof, on the Central Nervous System (CNS) were studied. The drug under study TPM showed little effect on the CNS, the same can not be said about the components. The most prominent CNS depressant effect was observed with Saccharum officinarum Linn. (EE) in that it lowered the spontaneous motor activity as well the exploratory -behavior of the animals. An exploration retarding effect of moderate degree, was evident with Imperata cylindrica Beauv. (UU), and Phragmites maxima Blatter & McCann (NN). Although the test drug did not alter the normal locomotor and/ or exploratory behavior of the treated animals, it did significantly (p<0.01) lower the locomotion of the amphetamine induced hyperactive animals. TPM along with its components (especially Desmostachya bipinnata Stapf. Root, KU), significantly reduced the gastro-intestinal motility of the treated animals (p<0.01). The test drug and its components lowered the body weight of the treated animals, on being administered chronically (30 days), with EE being the only exception.

Compact-SQAM for Power & Bandwidth Algorithm of Output Error Method (전력 및 대역폭 효율적인 디지틀 전송 시스템을 위한 협대역 중첩 직교 변조 방식)

  • 박일근;서종수
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.18 no.4
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    • pp.519-529
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    • 1993
  • A spectral and power efficient modulation technique, named Compact Superposed Quadrature Amplitude Modulation (Compact-SQAM), is introduced. The performance of Compact-SQAM system, in a Linearly and nonlinearly amplified single and multicarrier environment, in the presence of additive white Gaussian noise(AWGN), intersymbol interference(ISI), timing jitter and adjacent channel interference (ACI), is experimentally analyzed via computer simulation. Various channel conditions, such as channel spacing, between the main and adjacent channels and fade depth on the desired main channel, are examined. Our result shows that Compact-SQAM, and better P(e) performance that other modems using simple Butteroworth type postdetection receive filters. Especially, Compact-SQAM modem achieves higher efficiency of frequency utilization and better P(e) performance than other modems in the severly bandlimited nonlinear multicarrier channels.

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The fucose containing polymer (FCP) rich fraction of Ascophyllum nodosum (L.) Le Jol. protects Caenorhabditis elegans against Pseudomonas aeruginosa by triggering innate immune signaling pathways and suppression of pathogen virulence factors

  • Kandasamy, Saveetha;Khan, Wajahatullah;Kulshreshtha, Garima;Evans, Franklin;Critchley, Alan T.;Fitton, J.H.;Stringer, Damien N.;Gardiner, Vicki-Anne;Prithiviraj, Balakrishnan
    • ALGAE
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    • v.30 no.2
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    • pp.147-161
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    • 2015
  • Brown algal extracts have long been used as feed supplements to promote health of farm animals. Here, we show new molecular insights in to the mechanism of action of a fucose containing polymer (FCP) rich fraction from the brown seaweed Ascophyllum nodosum using the Caenorhabditis elegans-Pseudomonas aeruginosa PA14 infection model. FCP enhanced survival of C. elegans against pathogen stress, correlated with up-regulation of key immune response genes such as: lipases, lysozyme (lys-1), saponin-like protein (spp-1), thaumatin-like protein (tlp-1), matridin SK domain protein (msk-1), antibacterial protein (abf-1), and lectin family protein (lfp). Further, FCP caused down regulation of P. aeruginosa quorum sensing genes: (lasI, lasR, rhlI, and rhlR), secreted virulence factors (lipase, proteases, and elastases) and toxic metabolites (pyocyanin, hydrogen cyanide, and siderophore). Biofilm formation and motility of pathogenic bacteria were also greatly attenuated when the culture media were treated with FCP. Interestingly, FCP failed to mitigate the pathogen stress in skn-1, daf-2, and pmk-1 mutants of C. elegans. This indicated that, FCP treatment acted on the regulation of fundamental innate immune pathways, which are conserved across the majority of organisms including humans. This study suggests the possible use of FCP, a seaweed component, as a functional food source for healthy living.

A Comparison of ROCK Inhibitors on Human Bone Marrow-Derived Mesenchymal Stem Cell Differentiation into Neuron-Like Cells

  • Lee, Hyun-Sun;Kim, Kwang-Sei;O, Eun-Ju;Joe, Young-Ae
    • Biomolecules & Therapeutics
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    • v.18 no.4
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    • pp.386-395
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    • 2010
  • Bone marrow-derived mesenchymal stem cells (BM-MSC) are a multipotent cell population that can differentiate into neuron-like cells. Previously it has been reported that murine BM-MSC can differentiate into neuron-like cells by co-treatment with a Rho-associated kinase (ROCK) inhibitor -Y27632 and $CoCl_2$. In this study, we compared several ROCK inhibitors for the ability to induce human BM-MSCs to differentiate into neuron-like cells in the presence of $CoCl_2$. Y27632 with high specificity for ROCK at 1-30 ${\mu}M$ was best at inducing neuronal differentiation of MSCs. Compared to HA1077 and H1152, which also effectively induced morphological change into neuron-like cells, Y27632 showed less toxicity even at 100 ${\mu}M$, and resulted in longer multiple branching processes at a wide range of concentrations at 6 h and 72 h post-induction. H89, however, which has less specificity by inhibition of protein kinase A, S6 kinase 1 and MSK1 with similar or greater potency, was less effective at inducing neuronal differentiation of MSCs. Simvastatin, which can inhibit Rho, Ras, and Rac by blocking the synthesis of isoprenoid intermediates, showed little activity for inducing morphological changes of MSCs into neuron-like cells. Accordingly, the expression patterns for neuronal cell markers,including ${\beta}$-tubulin III, neuron-specific enolase, neurofilament, and microtubule-associated protein, were consistent with the pattern of the morphological changes. The data suggest that the ROCK inhibitors with higher specificity are more effective at inducing neuronal differentiation of MSCs.

Communications Protocol Used in the Wireless Token Rings for Bird-to-Bird

  • Nakajima, Isao;Juzoji, Hiroshi;Ozaki, Kiyoaki;Nakamura, Noboru
    • Journal of Multimedia Information System
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    • v.5 no.3
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    • pp.163-170
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    • 2018
  • We developed a multicast communication packet radio protocol using a time-sharing tablet system ("wireless token ring") to achieve the efficient exchange of files among packet radio terminals attached to swans. This paper provides an overview of the system and the protocol of the packet communications. The packet device forming the main part of the transceiver developed is the Texas Instruments CC2500. This device consists of one call-up channel and one data transmission channel and could improve error frame correction using FEC (forward error correction) with 34.8 kbps MSK and receiving power of at least -64 dBm (output 1 dBm at distance of 200 m using 3 dBi antenna). A time-sharing framework was determined for the wireless token ring using call sign ordinals to prevent transmission right loss. Tests using eight stations showed that resend requests with the ARQ (automatic repeat request) system are more frequent for a receiving power supply of -62 dBm or less. A wireless token ring system with fixed transmission times is more effective. This communication protocol is useful in cases in which frequency resources are limited; the energy consumed is not dependent on the transmission environment (preset transmission times); multiple terminals are concentrated in a small area; and information (position data and vital data) is shared among terminals under circumstances in which direct communication between a terminal and the center is not possible. The method allows epidemiological predictions of avian influenza infection routes based on vital data and relationships among individual birds based on the network topology recorded by individual terminals. This communication protocol is also expected to have applications in the formation of multiple in vivo micromachines or terminals that are inserted into living organisms.