• Title/Summary/Keyword: MRI safety

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Safety Management for MR-Guided Interventions

  • Cherkashin, Mikhail;Berezina, Natalia;Serov, Alexey;Fedorov, Artem;Andreev, Georgy;Kuplevatsky, Vladymir
    • Investigative Magnetic Resonance Imaging
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    • v.20 no.3
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    • pp.152-157
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    • 2016
  • Purpose: Operating room management is the serious and complex task for hospital managers and the common approach is to develop relevant standard operational procedures. From patient and staff safety perspective, operating room management should be well-studied and hospital should identify and address any potential risks. Simultaneous usage of different imaging and less-invasive treatment technologies demands strong management control. Materials and Methods: We have formed the multidisciplinary expert panel (surgeons, anesthesiologists, radiologists, healthcare managers etc.) for hybrid theater management standard operational procedure development. On the first stage the general concept of hybrid room design and patient routing was developed. The second stage included the technical details discussion. For patient safety improvement we modified the Surgical Safety Check-list in accordance with potential MRI-related safety challenges and concerns. Results: WHO Surgical Safety Checklist is a simple and easy-to use tool which includes three blocks of question (grouped by the surgery process). We have developed two additional blocks of questions for the intraoperative magnetic resonance investigation. It is very important to have a special detailed routing with a strong control of ferromagnetic devices and anesthesiology care. Conclusion: High-energy MRI (1.5-3.0T) is characterized by potential influence on patient and staff safety in case of hybrid surgery. It is obvious to have a strong managerial control of ferromagnetic devices and anesthesiology care. Surgical Safety Checklist is the validated tool for improving patient safety. Modification and customization of this check-list potentially provides the opportunity for surgery processes improving.

In vivo Imaging Biodistribution Profile of a New Macrocyclic Gadolinium Chelate as a Highly Stable Multifunctional MRI Contrast Agent

  • Sung, Bo Kyung;Jo, Yeong Woo;Chang, Yongmin
    • Investigative Magnetic Resonance Imaging
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    • v.23 no.1
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    • pp.34-37
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    • 2019
  • Gadolinium contrast agents (CAs) are integral components of clinical magnetic resonance imaging (MRI). However, safety concerns have arisen regarding the use of gadolinium CAs, due to their association with nephrogenic systemic fibrosis (NSF). Furthermore, recently the long-term retention of $Gd^{3+}-based$ CAs in brains patients with normal renal function raised another possible safety issue. The safety concerns of $Gd^{3+}-based$ CAs have been based on the ligand structure of $Gd^{3+}-based$ CAs, and findings that $Gd^{3+}-based$ CAs with linear ligand structures showed much higher incidences of NSF and brain retention of CAs than $Gd^{3+}-based$ CAs with macrocyclic ligand structure. In the current study, we report the in vivo biodistribution profile of a new highly stable multifunctional $Gd^{3+}-based$ CA, with macrocyclic ligand structure (HNP-2006). MR imaging using HNP-2006 demonstrated a significant contrast enhancement in many different organs. Furthermore, the contrast enhanced tumor imaging using HNP-2006 confirmed that this new macrocyclic CA can be used for detecting tumor in the central nervous system. Therefore, this new multifunctional HNP-2006 with macrocyclic ligand structure shows great promise for whole-body clinical application.

Prediction of Local Tumor Progression after Radiofrequency Ablation (RFA) of Hepatocellular Carcinoma by Assessment of Ablative Margin Using Pre-RFA MRI and Post-RFA CT Registration

  • Yoon, Jeong Hee;Lee, Jeong Min;Klotz, Ernst;Woo, Hyunsik;Yu, Mi Hye;Joo, Ijin;Lee, Eun Sun;Han, Joon Koo
    • Korean Journal of Radiology
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    • v.19 no.6
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    • pp.1053-1065
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    • 2018
  • Objective: To evaluate the clinical impact of using registration software for ablative margin assessment on pre-radiofrequency ablation (RFA) magnetic resonance imaging (MRI) and post-RFA computed tomography (CT) compared with the conventional side-by-side MR-CT visual comparison. Materials and Methods: In this Institutional Review Board-approved prospective study, 68 patients with 88 hepatocellulcar carcinomas (HCCs) who had undergone pre-RFA MRI were enrolled. Informed consent was obtained from all patients. Pre-RFA MRI and post-RFA CT images were analyzed to evaluate the presence of a sufficient safety margin (${\geq}3mm$) in two separate sessions using either side-by-side visual comparison or non-rigid registration software. Patients with an insufficient ablative margin on either one or both methods underwent additional treatment depending on the technical feasibility and patient's condition. Then, ablative margins were re-assessed using both methods. Local tumor progression (LTP) rates were compared between the sufficient and insufficient margin groups in each method. Results: The two methods showed 14.8% (13/88) discordance in estimating sufficient ablative margins. On registration software-assisted inspection, patients with insufficient ablative margins showed a significantly higher 5-year LTP rate than those with sufficient ablative margins (66.7% vs. 27.0%, p = 0.004). However, classification by visual inspection alone did not reveal a significant difference in 5-year LTP between the two groups (28.6% vs. 30.5%, p = 0.79). Conclusion: Registration software provided better ablative margin assessment than did visual inspection in patients with HCCs who had undergone pre-RFA MRI and post-RFA CT for prediction of LTP after RFA and may provide more precise risk stratification of those who are treated with RFA.

Noninvasive Rx of Breast Cancer by MR-guided High Intensity Focused Ultrasound

  • Moonen, Chrit
    • Proceedings of the KSMRM Conference
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    • 2005.09a
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    • pp.77-78
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    • 2005
  • A specific FUS-MRI platform was designed for breast cancer treatment. phased array technologies, sideways FUS transmission, and spatio-temporal temperature control in the complete region of interest, were combined for a novel therapy approach with enhanced safety and afficacy. A phase I clinical trial will start soon.

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Magnetic Resonance Imaging of a Current Density Component

  • Oh, Suk-Hoon;Park, Tae-Seok;Han, Jae-Yong;Lee, Soo-Yeol
    • Journal of Biomedical Engineering Research
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    • v.25 no.3
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    • pp.183-188
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    • 2004
  • Magnetic resonance current density imaging (MRCDI) is a useful method for measuring electrical current density distribution inside an object. To avoid object rotations during the conventional MRCDI scans, we have reconstructed current density component images by applying a spatial filter to the magnetic field data measured both inside and outside the object. To measure the magnetic field outside the object with MRI, we immersed the object in a water tank. To evaluate accuracy of the current density imaging, we have made a conductivity phantom with a corresponding finite element method model. We have compared the experimentally obtained current density images with the ones calculated by the finite element method. The average errors of the reconstructed current density images were 6.6 ∼ 45.4 % when the injected currents were 1 ∼ 24 mA. We expect that the current density component imaging technique can be used in diverse biomedical applications such as electrical therapy system developments and biological electrical safety analysis.

A Study on the Performance Improvement for Magnetic Resonance Imaging Examination by Using the 6-Sigma Application (6-시그마 기법을 이용한 자기공명영상 검사 실적 개선에 대한 연구)

  • Seoung, Youl-Hun
    • Journal of the Korea Safety Management & Science
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    • v.13 no.2
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    • pp.243-249
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    • 2011
  • The purpose of the study was to improve of performance for Magnetic Resonance Imaging (MRI) examination in the department of radiology. It was performed DMAIC (Define, Measure, Analyze, Improve, and Control). In the stage of definition, The fifth kinds of CTQ (critical to quality) by the kindness, the waiting time, the examination explanation, the waiting time and the waiting environment were selected by voice of customer. In the stage of measurement, the performed examinations and the reservation waiting time were measured each 1.77 and 1.69 sigma. In the stage of analysis, the potential key causes were determined the limited working hours and the difference of examination time of various entries. In the stage of improvement, MRI were performed with the operating system of 24 hours examination and the optimization of the difference of examination time by among of 30 minutes, 40 minutes, 50 minutes. Finally, the number of examinations and reserved waiting days were measured by each 3.17 and 1.71 sigma in the control stage.

Muscular Adaptations and Novel Magnetic Resonance Characterizations of Spinal Cord Injury

  • Lim, Woo-Taek
    • Physical Therapy Korea
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    • v.22 no.2
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    • pp.70-80
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    • 2015
  • The spinal cord is highly complex, consisting of a specialized neural network that comprised both neuronal and non-neuronal cells. Any kind of injury and/or insult to the spinal cord leads to a series of damaging events resulting in motor and/or sensory deficits below the level of injury. As a result, muscle paralysis (or paresis) leading to muscle atrophy or shrinking of the muscle along with changes in muscle fiber type, and contractile properties have been observed. Traditionally, histology had been used as a gold standard to characterize spinal cord injury (SCI)-induced adaptation in spinal cord and skeletal muscle. However, histology measurements is invasive and cannot be used for longitudinal analysis. Therefore, the use of conventional magnetic resonance imaging (MRI) is promoted to be used as an alternative non-invasive method, which allows the repeated measurements over time and secures the safety against radiation by using radiofrequency pulse. Currently, many of pathological changes and adaptations occurring after SCI can be measured by MRI methods, specifically 3-dimensional MRI with the advanced diffusion tensor imaging technique. Both techniques have shown to be sensitive in measuring morphological and structural changes in skeletal muscle and the spinal cord.

Relationship between Hospital Safety Symbol Shapes and Memory (병원 안전 심볼의 형태와 기억과의 관계)

  • Seok-Hwan Bae;Myung-Chul Park;Jae-Sang You;Yong-Gwon Kim;Cheul-Ho Ryoo;Dong-Hyun Oh
    • Journal of radiological science and technology
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    • v.46 no.2
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    • pp.115-122
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    • 2023
  • The purpose of this study was to examine the association between the shapes and colors of emergency exit symbols, magnetic field warning symbols, and radiation zone symbols used in hospitals for staff and patient safety and their effects on cognitive memory. The hippocampal region's signal intensity(SI) was analyzed using fMRI. The Symbol 2 (1.75±0.54) with a green background had the highest signal intensity (SI) for emergency exits, according to the findings. The black symbol 2 (1.60±0.51) with a yellow background had the highest signal intensity (SI) for the magnetic field warning symbol, followed by the black symbol 1 (1.59±0.65) with an orange background. The black symbol 2 (1.59±0.59) with a yellow background and the black symbol 3 (1.58±0.52) with an orange background had the low signal intensity with slight differences as for the radiation zone symbols. In conclusion, it was determined that the signal intensity of the black symbol with a yellow background was the highest in the magnetic field area and radiation area. This implies that symbols with a high signal intensity (SI) must be utilized intensively. To ensure that the correct meaning of the symbols is communicated in the future, they must also be utilized regularly and continually in disaster safety education.

Study on the Correlation between the Change in SAR and Temperature of the Human Head by use Dental Implant on 3.0T Brain MRI : Using the XFDTD program (3.0T Brain MRI 검사 시 치아임플란트 시술 유무와 인체의 SAR, 체온 변화와의 상관관계에 관한 연구 : XFDTD 프로그램을 이용)

  • Choe, Dea-yeon;Kim, Dong-Hyun
    • Journal of the Korean Society of Radiology
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    • v.11 no.3
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    • pp.139-146
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    • 2017
  • At the Brain MRI examination, RF Pulse are irradiated on the human head in order to acquire MR images. At this time, a considerable part of the irradiated RF Pulse energy is absorbed in our body and the temperature of the human head will rise depending on the degree of exposure, so it will affect the human head. Even if the same RF Pulse energy is given, if the metal is inserted in the human head, the conductivity of the human head is greatly increased by the metal, so the SAR value increases and the temperature also rises. Therefore, we started this research with the question as to whether there is difference between the change in SAR value and temperature displayed on the head of the human according to use or not of the dental implant. Experiments were using the XFDTD program on a 128 MHz RF Pulse frequency by a 3.0 tesla MRI. We can see that both are increasing that the average value of SAR and temperature that absorbed by the human head model used the dental implant. In addition, the average maximum SAR value and the maximum temperature rise in the brain part are shown below the international safety standard value but the influence can not be ignored because of the result may change according to the increase in the number of dental implant. And as future tasks. we need to the simulation of temperature rise and SAR due to an increase in the number of implants and volumes of teeth, dental implant material.

Unwanted effects due to interactions between dental materials and magnetic resonance imaging: a review of the literature

  • Chockattu, Sherin Jose;Suryakant, Deepak Byathnal;Thakur, Sophia
    • Restorative Dentistry and Endodontics
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    • v.43 no.4
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    • pp.39.1-39.20
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    • 2018
  • Magnetic resonance imaging (MRI) is an advanced diagnostic tool used in both medicine and dentistry. Since it functions based on a strong uniform static magnetic field and radiofrequency pulses, it is advantageous over imaging techniques that rely on ionizing radiation. Unfortunately, the magnetic field and radiofrequency pulses generated within the magnetic resonance imager interact unfavorably with dental materials that have magnetic properties. This leads to unwanted effects such as artifact formation, heat generation, and mechanical displacement. These are a potential source of damage to the oral tissue surrounding the affected dental materials. This review aims to compile, based on the current available evidence, recommendations for dentists and radiologists regarding the safety and appropriate management of dental materials during MRI in patients with orthodontic appliances, maxillofacial prostheses, dental implants, direct and indirect restorative materials, and endodontic materials.