• Spatial Information Research
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• v.10 no.1
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• pp.61-76
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• 2002

Mobile map services using PDA are prevailing because of the rapid developments of techniques of the internet and handhold devices recently. While the volume of spatial data is tremendous and the spatial operations are time-intensive, the PDA has small size memory and a low performance processor. Therefore, the spatial index for PDA should be small size and efficiently filter out the candidate objects of spatial operation as well. This paper proposes a spatial index far PDA called MHF(Multilevel Hashing File). The MHF has simple structure for storage efficiency and uses a hashing technique, which is direct search method, for search efficiency. This paper also designs a compression technique for MBR. which occupies almost 80% of index data in the two dimensional case. We call it HMBR. Although the HMBR technique reduces the MB\ulcorner size to almost a third, it shows good filtering efficiency because of no information loss by quantization in case of small objects that occupy a major portion. Our experimental tests show that the proposed MHF index using HMBR technique is appropriate for PDA in terms of the size of index, the Number of MBR comparisons, the filtering efficiency and the execution time of spatial operations.

• Korean Journal of Adult Nursing
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• v.12 no.3
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• pp.323-333
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• 2000

The purpose of this study was to determine the impact of situational, clinical and psychsoical factors on treatment-seeking behavior among those with acute myocardial infarction(AMI). This study used a retrospective, descriptive design. The sample consisted of 72 patients aged over 30 and who were diagnosed with an acute myocardial infarction at two large university-affiliated medical centers from July 1, 1998 to March 30, 2000. But of 72, patients 5 who were an outlier in treatment-seeking time were deleted. Data were collected by using questionnaires, which included demographic data, situational, clinical and psychosocial data. Also patient interviews and chart review were used to obtain information related to treatment-seeking time. The results of this study were summarized as follows ; 1. Mean time from the onset of AMI symptoms to arrival at the hospital was $12.09{\pm}11.44$ hours; 2. Treatment-seeking time was not significantly different by age, gender, or education; 3. Most(44 or 65.78%) patients were at home when they began having AMI symptoms. The remaining patients were either in a public area, workplace or in a car. Patients at home delayed longer than those who had their first symptoms elsewhere, but not significantly different. Also, most patients were with another person when they began to experience AMI symptoms: a spouse(25 or 37.3%), other family member(31 or 46.3%); the remaining 11 were alone. There were no significant differences in treatment-seeking time based on whether alone or with others. Most patients(46 or 68.7%) used an ambulance rather than taking private transportation, and patients who used an ambulance were delayed longer than those who used private transportation, but there were no significant differences; 4. Time to treatment-seeking was not significantly different by blood pressure, heart rate on admission and the peak CK-MB, CPK and Cholesterol level, Killips class; 5. There were no significant statistical differences in treament-seeking times by anxiety level, mood status or control ability.

• Asian-Australasian Journal of Animal Sciences
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• v.29 no.4
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• pp.464-470
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• 2016

The objective of this study was to investigate the accuracy of imputation from low density (LDC) to moderate density SNP chips (MDC) in a Thai Holstein-Other multibreed dairy cattle population. Dairy cattle with complete pedigree information (n = 1,244) from 145 dairy farms were genotyped with GeneSeek GGP20K (n = 570), GGP26K (n = 540) and GGP80K (n = 134) chips. After checking for single nucleotide polymorphism (SNP) quality, 17,779 SNP markers in common between the GGP20K, GGP26K, and GGP80K were used to represent MDC. Animals were divided into two groups, a reference group (n = 912) and a test group (n = 332). The SNP markers chosen for the test group were those located in positions corresponding to GeneSeek GGP9K (n = 7,652). The LDC to MDC genotype imputation was carried out using three different software packages, namely Beagle 3.3 (population-based algorithm), FImpute 2.2 (combined family- and population-based algorithms) and Findhap 4 (combined family- and population-based algorithms). Imputation accuracies within and across chromosomes were calculated as ratios of correctly imputed SNP markers to overall imputed SNP markers. Imputation accuracy for the three software packages ranged from 76.79% to 93.94%. FImpute had higher imputation accuracy (93.94%) than Findhap (84.64%) and Beagle (76.79%). Imputation accuracies were similar and consistent across chromosomes for FImpute, but not for Findhap and Beagle. Most chromosomes that showed either high (73%) or low (80%) imputation accuracies were the same chromosomes that had above and below average linkage disequilibrium (LD; defined here as the correlation between pairs of adjacent SNP within chromosomes less than or equal to 1 Mb apart). Results indicated that FImpute was more suitable than Findhap and Beagle for genotype imputation in this Thai multibreed population. Perhaps additional increments in imputation accuracy could be achieved by increasing the completeness of pedigree information.

• Natural Product Sciences
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• v.23 no.4
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• pp.265-269
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• 2017

Pseudolaric acids of Pseudolarix kaempferi (Pinaceae) have been known as diterpenoids with potent anti-fungal-, anti-microbial, and cytotoxic activities. In the present study, the five MeOH extracts were prepared from the five plant part (root bark, stem bark, leaf, the inner part of root, and cone) to find the relation between the concentration of pseudolaric acids and cytotoxicity. Pseudolaric acids B and C were isolated from the root bark of P. kaempferi to use them as standard compounds. The five extracts were tested on cytotoxicity against six cancer cell lines, A549 (lung), HCT116 (colon), MDA-MB-231 (breast), SNU638 (stomach), and SK-hep-1 (liver) by SRB assay, but against K562 (leukemia) by SRB- or MTT assay. HPLC quantification were performed on a Shisheido Capcell PAK C18 column ($5{\mu}m$, $4.6mm{\times}250mm$) using 254 nm wavelength. The cytotoxicity ($IC_{50}$, $0.36{\mu}g/ml$ on K562 cell lines) of the root bark extract was potent and the content (101.1 mg/g extract) of pseudolaric acid B was very high in the root bark. These results suggest that the MeOH extract obtained from the root bark could be developed as the anti-cancer agent with a high quantity of pseudolaric acid B.

• Korean Journal of Applied Biomechanics
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• v.19 no.1
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• pp.59-66
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• 2009

The purpose of this study was to evaluate flatness of swing plane and determine swing plane type using 3-D swing plane analysis from young elite male golf players. This study also investigate the possibility of determination of swing plane using other kinematic parameters except flatness. As results, no correlations was found between flatness and handicap. Comparison of flatness between single plane and multiple plane swing group were performed and found a significant difference. The error range of flatness, 10cm, which was used for distinguish swing plane type was effective since significant differences were found at MB, EB, and EF. These differences were typical characteristics to classify two swing styles. Other kinematic parameters such as unit vector components of shaft and displacement of shaft end point also compared per event but found no significant differences. However, the moving patterns of these parameters during a golf swing showed such characteristics of each swing plane type well that these parameters could be used to determine swing style as an indirect barometers.

• Journal of the Institute of Convergence Signal Processing
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• v.6 no.4
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• pp.206-211
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• 2005

We describe the design for a correlator and an access code generator in bluetooth system. These are used for a connection setting, a packet decision and a clock synchronization between Bluetooth units. The correlator consists of two blocks; carry save adder based on Wallace tree and threshold-value decision block. It determines on an useful packet and clock-synchronization for input signal of 1.0Mbps through the sliding-window correlating. The access-code generator also consists of two blocks; BCH(Bose-Chadhuri-Hocquenghem) cyclic encoder and control block. It generates the access-codes according to four steps' generation process based on Bluetooth standard. In order to solve synchronization problem, we make use of any memory as a pseudo random sequence. The proposed correlator and access-code generator were coded with VHDL. An FPGA Implementation of these modules and the simulation results are proved by Xilinx chip. The critical delay and correlative margin based on synthesis show the 4.689ns and the allowable correlation-error up to 7-bit.

• The Journal of Korean Medicine
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• v.18 no.1
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• pp.198-207
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• 1997

To explore the action mechanism of Ijintang in the brain, the authors investigated the effects of Ijintang fractions on MgNaK ATPase and MgCa ATPase in rat brain synaptosomes prepared from cerebral cortex. The activities of MgNaK ATPase and MgCa ATPase were assayed by the level of inorganic phosphate liberated from the hydrolysis of ATP. Fraction WH-95-7 at the concentration of $10^{-2}%$ decreased the activity of MgNaK ATPase about 34.1% and also reduced the activity of MgCa ATPase about 49.3% But, other fractions (WB-95-7, WC-95-7, MB-95-7, MC-95-7, MH-95-7) did not significantly changed the activities of the MgNaK ATPase and MgCa ATPase The decreased activity of MgNaK ATPase by WH-95-7 will decrease the rate of $Ca^{2+}$ efflux, probably via an Na-Ca exchange mechanism and will increase the rate of $Ca^{2+}$ entry by the depolarization of nerve terminals. The reduced activity of MgCa ATPase by WH-95-7 will result in the decreased efflux of $Ca^{2+}$. As a conclusion, it can be speculated that lithium elevates the intrasynaptosomal $Ca^{2+}$ concentration via inhibition of the activities of MgNaK ATPase and MgCa ATPase. and this increased $[Ca^{2+}]i$ will cause the release of neurotransmitters.

• JSTS:Journal of Semiconductor Technology and Science
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• v.11 no.2
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• pp.121-129
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• 2011

It is progressing as new advents and remarkable developments of mobile device every year. On the upper line reason, NAND FLASH large density memory demands which can be stored into portable devices have been dramatically increasing. Therefore, the cell size of the NAND Flash memory has been scaled down by merely 50% and has been doubling density each per year. [1] However, side effects have arisen the cell distribution and reliability characteristics related to coupling interference, channel disturbance, floating gate electron retention, write-erase cycling owing to shrinking around 20nm technology. Also, FLASH controller to manage shrink effect leads to speed and current issues. In this paper, It will be introduced to solve cycling, retention and fail bit problems of sub-deep micron shrink such as Virtual negative read used in moving read, randomization. The characteristics of retention, cycling and program performance have 3 K per 1 year and 12.7 MB/s respectively. And device size is 179.32 $mm^2$ (16.79 mm ${\times}$ 10.68 mm) in 3 metal 26 nm CMOS.

• Journal of Life Science
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• v.17 no.6 s.86
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• pp.772-777
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• 2007

A rice OsLeuD gene for small subunit of 3-isopropylmalate isomerase (IPMI) (EC 4.2.1.33) has been isolated. OsLeuD gene is located on 109.3 cM of chromosome 2. OsLeuD gene was expressed abundantly in metabolically active organs including leaves and developing seeds, indicating that OsLeuD gene expression is developmentally regulated. The cDNA of OsLeuD gene was coded for 257 amino acids which showed 58% and 48% homology to small subunits of IPMI in OsLeuD genes of cyanobacteria and green sulfur bacteria, respectively. The molecular character of OsLeuD is closely related to those of photosynthetic bacteria rather than those of eukaryotes including fungi and yeast. This suggests that OsLeuD gene in chromosomal genome of plants may possibly be originated from chloroplast genome.

• Journal of the Korean Society for Library and Information Science
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• v.51 no.1
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• pp.245-269
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• 2017

To assess and understand the level of job burnout among the medical librarians and identify the factors affecting it, email survey, consisting of questions regarding personal background, organization characteristics, degree of burnout, and coping activities, was administered for two weeks in December 2016, to the librarians in 138 institutions affiliated with the Korean Medical Library Association. MBI-GS is used as a burnout measuring instrument. Data collected from 158 librarians (response rate 65.6%), were analyzed by descriptive statistics, t-test, ANOVA, and correlation analysis methods. According to MB-GS norm, respondents experience moderate level of exhaustion and professional efficacy, however the level of cynicism is extremely high. There are significant statistical differences in burnout, depending on age, medical librarian certificate, work experience, type of library, job coverage, and coping activities. There are also statistical significant correlations between workload, role conflict, decision making process and performance evaluation, organization communication, IT environment, continuing education and burnout. Based on the results, recommendations to alleviate burnout are suggested in individual, organizational, and professional association context.