• 제목/요약/키워드: MIB-1

검색결과 992건 처리시간 0.031초

자연수중 이취미 물질의 분말활성탄 흡착시 염소의 영향 (Effect of Chlorine on PAC Adsorption to Remove Odor Compound in Natural Water)

  • 이정규;김동윤
    • 상하수도학회지
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    • 제14권4호
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    • pp.350-355
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    • 2000
  • Powdered activated carbon(PAC) is widely used to control 2-MIB와 geosmin causing earthy-musty odor in water supplies. It was known that chlorine is one of the chemicals often come into contact with activated carbon. But activated carbon react with chlorine and surface oxide accumulate on carbon surface. As result, adsorption capacity of activated carbon is reduced. To investigate the effect of chlorine on the PAC's ability to adsorb 2-MIB and Geosmin, a series of experiments was carried out to show (1) the effect of aqueous chlorine doses on the ability of PAC to adsorb 2-MIB and Geosmin from Lake Heodong water. (2) the effect of delaying the chlorine addition after PAC had been added (to simulate the effect of using an alternative point of chlorine addition). As a result of experiment, as chlorine dose increased correspondingly decreased the capacity of activated carbon to adsorb 2-MIB and geosmin. Even though previously adsorbed 2-MIB and geosmin released, as result of the application of delaying the chlorine adding was more beneficial than simultaneous adding chlorine with PAC.

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Rebinding Dynamics of CO Following Photodissociation of 4.0 M Guanidine HCl-Denatured Carbonmonoxyhemoglobin

  • Park, Jae-Heung;Lee, Tae-Gon;Kim, Joo-Young;Chowdhurry, Salina A.;Lim, Man-Ho
    • Bulletin of the Korean Chemical Society
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    • 제30권4호
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    • pp.913-916
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    • 2009
  • Femtosecond vibrational spectroscopy was used to probe the dynamics of CO rebinding to hemoglobin (Hb), denatured by 4.0 M GdnHCl in $D_2O# at 283 K, after photolysis of HbCO. The stretching mode of $^{13}CO$ bound to the denatured $Hb^{13}CO$ showed a single band centered at 1922 $cm^{-1}$, indistinguishable from that of denatured $Mb^{13}CO$. Geminate rebinding of CO to the denatured Hb was accelerated more than 1000 times, suggesting that the native structure of the Hb is required to suppress efficient geminate rebinding of CO, as is the case in Mb. The geminate yield and rate for CO rebinding are almost the same in both the denatured Hb and Mb. Similarity in the equilibrium spectrum and rebinding dynamics of CO indicates that the state of the denatured Hb is very similar to that of the denatured Mb. In the denatured Hb, quaternary contact of the protein is likely severed, with the denatured protein existing as an independent subunit much like Mb.

Effects of Inoculated Bacillus subtilis on Geosmin and 2-Methylisoborneol Removal in Suspended Growth Reactors Using Aquacultural Waste for Biofloc Production

  • Luo, Guozhi;Wang, Jiao;Ma, Niannian;Liu, Zefeng;Tan, Hongxin
    • Journal of Microbiology and Biotechnology
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    • 제26권8호
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    • pp.1420-1427
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    • 2016
  • Geosmin and 2-methylisoborneol (2-MIB) are two of the most common taint compounds that adversely affect the quality of aquacultural animals. In the present study, 94% of geosmin and 97% of 2-MIB in suspended growth reactors producing bioflocs (SGRs) with aquaculture waste were removed after inoculation with Bacillus subtilis, significantly higher than that of control SGRs (70% of geosmin and 86.4% of 2-MIB). The lowest concentrations of geosmin and 2-MIB achieved in the effluent of the SGRs were 2.43 ± 0.42 ng/l and 2.23 ± 0.15 ng/l, respectively. The crude protein content of the bioflocs produced in the SGRs was 35 ± 4%. The NH4+-N and NO2--N concentrations in the effluent of the reactors were 1.13 ± 0.21 mg/l and 0.42 ± 0.04 mg/l, respectively. These results suggest that inoculated with Bacillus subtilis, SGRs have a better performance to reuse the nitrogen in fish waste and to remove geosmin and 2-MIB from the culture water efficiently.

Efficient Adsorption of Methylene Blue from Aqueous Solution by Sulfuric Acid Activated Watermelone Rind (Citrullus lanatus)

  • Lee, Seo-Yun;Choi, Hee-Jeong
    • 공업화학
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    • 제32권3호
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    • pp.348-356
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    • 2021
  • The lignocellulose-based dried watermelon rind (WR) was modified with sulfuric acid, namely SWR for enhancement of methylene blue (MB) adsorption from the aqueous solution. According to FT-IR analysis, after the modification of WR with sulfuric acid, the functional groups of R-SO3H, COOH and -OH groups was formated or enhanced on the surface of the WR. Moreover, the point of zero charge (pHpzc) was changed from 6.3 to 4.1 after modification, which widened the range for adsorbing of cationic dye MB. The adsorption process of MB onto the SWR was suitable for pseudo-2nd-order and Langmuir model and the maximum adsorption capacity of Langmuir was found to be 334.45 mg/g at pH 7. In adition, the adsorption process occurs through the electrostatic interaction, hydrogen bridge formation, electron donor-acceptor relationship, and 𝜋-𝜋 electron dispersing force between functional groups on the carbon surface with MB molecules. Depending on functional groups available on the SWR surface, the MB adsorption mechanism can occur in combination with various interactions.

Improvement of Motor Behavior of Parkinson's Disease Animal Model by Nurr1 Transfected Human Embryonic Stem Cells

  • Lee, Chang-Hyun;Cho, Hwang-Yun;Kim, Yong-Sik;Kim, Eun-Young;Lee, Won-Don;Park, Sepill;Lim, Jin-Ho
    • 한국동물번식학회:학술대회논문집
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    • 한국동물번식학회 2004년도 춘계학술발표대회
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    • pp.274-274
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    • 2004
  • The purpose of this study is to evaluate the efficacy of in vitro differentiated human embryonic stem (MB03) cells expressing Nurr1 in relief of symptomatic motor behavior of Parkinson's disease (PD) animal models. MB03 cell was genetically modified to express Nurr1 protein (Nr#24/MB03) and was induced to differentiate according to 2- /4+ protocol using retinoic acid and ascorbic acid. (omitted)

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13(E)-Labd-13-ene-8$\alpha$, 15-diol isolated from Brachyglottis monroi Induces Apoptosis on Human Breast Cancer MDA-MB231 cell line

  • Lim, Jin-A;Lee, Jeong-Ho;Lee, In-A;Nigel, B;Baek, Seung-Hwa
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.141.1-141.1
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    • 2003
  • The inhibitory effect of 13(E)-Labd-13-ene-8$\alpha$ 15-diol(1), isolated from the ethanol extract of Brachyglottis monroi, on the proliferation of human breast cancer MDA-MB231 cells was examined. Compound (1) at concentration as high as 16$\mu$/$m\ell$ has inhibited the proliferation of MDA-MB231 and this cytotoxic effect was increased in a time and dose-dependent manners. (omitted)

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$Ti:LiMbO_3$ 광변조기를 이용한 저주파 전계센서의 개발 (Developments of Low Frequency Electric Field Sensor using $Ti:LiMbO_3$ Optical Modulator)

  • 최영규
    • 센서학회지
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    • 제10권4호
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    • pp.214-221
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    • 2001
  • 비대칭 도파로 마흐젠더(Mach-Zehnder)형 $Ti:LiMbO_3$ 광변조기를 이용하여 아주 낮은 저주파대(ELF:Extremely Low Frequency)의 전계계측을 위한 센서개발을 시도하였다. $Ti:LiMbO_3$ 광변조기를 이용하는 전계센서의 감도는 광변조기의 전극구조에 따라 크게 달라지는 것을 알 수 있었다. 이의 확인을 위한 실험적 연구로서 플레이트(plate)형 프로브안테나를 부착한 광변조기를 제작하여 저주파 전계강도를 측정하였다. 전계강도의 측정은 주파수범위 60 Hz 에서 100 kHz 까지, 전계강도 0.1 V/cm 에서 60 V/cm 까지의 범위를 측정하였다. $10\;mm{\times}10\;mm$ 프로브안테나의 경우, 60 Hz, 0.1 V/cm의 피측정전계에서 $10^{-2}\;mV$의 감도를 얻을 수 있었다. 저주파 전계강도를 측정하기 위해서는 넓은 유효면적을 갖는 플레이트형 프로브안테나가 일반적인 다이폴 안테나보다 유용하다는 것을 확인하였다. 피측정 전자계의 주파수 범위에 따라 안테나의 유효면적을 적당히 조절한다면 더 좋은 센서의 감도를 얻을 수도 있다.

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MB-OFDM 시스템에서 Packet Synchronization Sequence를 사용한 채널추정 방식 (Channel Estimation Method Using Packet Synchronization Sequence for MB-OFDM System)

  • 손성환;이경탁;김재명
    • 한국통신학회논문지
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    • 제30권12A호
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    • pp.1174-1182
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    • 2005
  • 본 논문에서는 고속의 데이터 전송률(110Mbps${\~}$480Mbps)을 갖는 WPAN을 위해 IEEE802.15 TG3a의 표준안 중 하나로 제안된 MB-OFDM(Multi-Band OFDM) 시스템을 위한 새로운 채별 추정 기법을 제안한다. 제안한 추정기법은 타이밍 동기 등을 위해서 제시하고 있는 PS(Packet Synchronization)신호의 상관특성을 사용한 것으로 기존 LS(Least Square) 기반의 채널 추정 방법에 비해 잡음의 영향을 줄일 수 있는 장점이 있으며 채널 추정을 위해 만들어진 CE(Channel Estimation)신호를 사용하지 않아도 되기 때문에 프리엠블로 제시된 심볼의 수를 줄일 수 있는 장점이 있다. 성능분석을 위해 IEEE802.15 TG3a에서 제시하고 있는 S-V 채널하에서 기존의 방법과 제안한 채널추정 방법을 컴퓨터 모의실험 하였으며 그 결과 Eb/N0에서 약 1${\~}$1.5dB 정도의 성능을 향상시킬 수 있었다.

개심술환자에 있어 혈청 Troponin-T 농도의 변화에 관한 연구 (Changes of Serum Troponin-T Concentrations in Patients with Open Heart Surgery)

  • 박동욱;최석철;김윤규;박종원;조관현
    • Journal of Chest Surgery
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    • 제31권2호
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    • pp.125-133
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    • 1998
  • 이 연구는 심근손상이 예상되는 개심술 환자들을 대상으로 수술에 따른 TnT의 혈중내 농도변화를 추적하여 심근세포 손상의 진단적 지표로서의 유용성을 조사하였고 기존의 효소진단 방법인 CK-MB 백분율 및 LDH1/LDH2비와 유용성을 비교 검토하였다. 본 연구는 1996년 1월부터 1996년 6월까지 인제대학교 부산백병원에서 개심술을 받은 성인 환자 중 술전 혈청 TnT 농도가 정상 범위였던 30명을 선정하여 시간대별 채혈로 시행되었다. 연구의 목적에 따라 환자들을 I 군(대동맥 차단시간 60분 이하, n=15)과 II군(대동맥 차단시간 60분 이상, n=15)으로 나누어 비교 조사하여 다음과 같은 결과를 얻었다. 1. 혈청 TnT의 농도는 양 군 모두 수술 중 상승하여 대동맥 차단의 제거후 유의하게 증가하였다(p<0.001). I 군에서는 술후 1일에 최고치(1.10$\pm$0.19 ng/ml)에 도달하였고 II 군에서는 체외순환 종료시 최고치(1.88$\pm$0.42 ng/ml)에 도달하여 이후 술후 7일까지 양군 모두 대조치에 비해 유의한 증가가 지속되었다(p<0.01). 2. CK-MB/total CK(이하 CK-MB 백분율 이라 함)의 경우 양 군 모두 수술 시작과 함께 유의하게 증가하여(p<0.001) 체외순환 종료시 최고치를 보였고 이후 술후 1일째까지 유의한 상승을 보였으나 술후 3일에는 기준치로 돌아옴으로써 혈청TnT에 비해 민감도가 떨어졌다. 3. LDH1/LDH2비는 수술동안 및 술후시기 전체에 걸쳐 대조치에 비해 유의한 변화가 없었다(p>0.05). 4. 수술동안의 혈청 TnT 농도와 CK-MB 백분율 변화간에는 의미있는 상관관계를 보였다(r=0.64, p<0.05). 5. I 군에 비해 II 군에서 혈청 TnT 농도는 대동맥 차단제거 시작 직전부터 술후 1일까지 유의한 증가를 보여(p<0.05) 대동맥 차단 시간의 지속 정도가 심근세포 손상의 중요한 인자임을 확인할 수 있었다. 결론적으로 혈청 TnT는 심근세포 손상에 있어 유용한 기준지표가 됨으로 향후 급성심근 경색증의 진단 뿐만 아니라 개심술에 따른 심근세포 손상 정도의 예측과 술후 환자의 감시에 표식자로서의 중요성이 기대 되었다.

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Vibrational Relaxation of Cyanate or Thiocyanate Bound to Ferric Heme Proteins Studied by Femtosecond Infrared Spectroscopy

  • Park, Seongchul;Park, Jaeheung;Lin, Han-Wei;Lim, Manho
    • Bulletin of the Korean Chemical Society
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    • 제35권3호
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    • pp.758-764
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    • 2014
  • Femtosecond vibrational spectroscopy was used to measure the vibrational population relaxation time ($T_1$) of different anions bound to ferric myoglobin ($Mb^{III}$) and hemoglobin ($Hb_{III}$) in $D_2O$ at 293 K. The $T_1$ values of the anti-symmetric stretching (${\nu}_1$) mode of NCS in the $NCS^-$ bound to $Mb^{III}$ ($Mb^{III}$NCS) and $Hb_{III}$ ($Hb_{III}$NCS) in $D_2O$ are $7.2{\pm}0.2$ and $6.6{\pm}0.2$ ps, respectively, which are smaller than that of free NCS. in $D_2O$ (18.3 ps). The $T_1$ values of the ${\nu}_1$ mode of NCO in the $NCO^-$ bound to $Mb^{III}$ ($Mb^{III}$NCO) and $Hb_{III}$ ($Hb_{III}$NCO) in $D_2O$ are $2.4{\pm}0.2$ and $2.6{\pm}0.2$ ps, respectively, which are larger than that of free $NCO^-$ in $D_2O$ ($1.9{\pm}0.2$ ps). The smaller $T_1$ values of the ${\nu}_1$ mode of the heme-bound NCS suggest that intramolecular vibrational relaxation (VR) is the dominant relaxation pathway for the excess vibrational energy. On the other hand, the longer $T_1$ values of the ${\nu}_1$ mode of the heme-bound NCO suggest that intermolecular VR is the dominant relaxation pathway for the excess vibrational energy in the ${\nu}_1$ mode of $NCO^-$ in $D_2O$, and that intramolecular VR becomes more important in the vibrational energy dissipation of the ${\nu}_1$ mode of NCO in $Mb^{III}$NCO and $Hb_{III}$NCO.