• Molecules and Cells
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• v.37 no.1
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• pp.9-16
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• 2014

ADP-ribosylation is a type of posttranslational modification catalyzed by members of the poly(ADP-ribose) (PAR) polymerase superfamily. ADP-ribosylation is initiated by PARPs, recognized by PAR binding proteins, and removed by PARG and other ADP-ribose hydrolases. These three groups of proteins work together to regulate the cellular and molecular response of PAR signaling, which is critical for a wide range of cellular and physiological functions.

• Bulletin of the Korean Chemical Society
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• v.11 no.6
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• pp.511-515
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• 1990

Ab initio calculations with MP3 and CISD method were performed for the FCO and $FCO^+$. The equilibrium geometry of FCO shows the reasonable agreement with experimental values. $FCO^+$ has a linear geometry with $R_{CF}=1.213\;and\;R_{CO}=1.118{\AA}$. The quadratic force constants of $FCO^+$ are 23.21 md ${\AA}^{-1}$ for CO stretch and 12.38 md ${\AA}^{-1}$ for CF stretch. The cubic force constants and the other molecular constants are also calculated.

• Proceedings of the Korean Information Science Society Conference
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• 1998.10a
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• pp.612-614
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• 1998

DNS는 인터넷상에서 도메인 네임과 IP 주소간의 상호 전환의 동작을 수행하는 시스템이다. DNS상에서 도메인 네임이나 IP 주소를 요청하는 질의나 이에 대한 응답은 네트워크상에서 UDP를 사용한 메시지 형식으로 전송한다. 이때 제 3자의 개입에 의한 조작의 가능성이 있다. 이러한 질의와 응답 메시지의 조작을 방지하고자 RFS2065에서는 RSA 공개키 방식을 사용하였다. RSA 공개키 방식은 현제 국내에서 직접사용하기에는 많은 애로 사항이 있으며 속도 측면에서 좋지 않은 면을 보여준다. 본 논문에서는 Pseudonoise Sequence와 MD5를 사용하여 DNS 상에서의 안전한 질의 응답을 가능하게 하고자 한다. Pseudonoise Sequence와 MD5를 사용함으로써 메시지를 암오화하지않아도 되며 또한 많은 계산을 요구하지 않는다. 메시지에 Pseudonoise Sequence를 기입하고, 그 메시지의 MD5를 송수신 측에서 검사함으로써 제 3자 개입에 의한 조작 방지와 메시지 데이터의 무결성을 보할 수 있다.

• Proceedings of the Safety Management and Science Conference
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• 2005.11a
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• pp.300-310
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• 2005

Mahalanobis Taguchi System (MTS) is developed by Genishi Taguchi as a part of his quality engineering methodology. The basic idea of Taguchi's quality engineering is looking for the way of effectiveness of analyzing multivariate system. In the MTS, with the standardized variables of healthy normal data, Mahalanobis Distance(MD) calculated and that can be discriminate between normal and abnormal objects. If this discrimination process is successful, next step is optimization which is try to reduce number of attributes by neglecting less effective attributes to MD. Orthogonal Array (OA) and Signal to Noise ratio (S/N) are used to evaluate the amount contribution of each attribute to the MD. Wisconsin Breast Cancer study, from machining learning repository at University of California at Irvine, used for examining the discriminant ability of MTS.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2004.05a
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• pp.62-65
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• 2004

Recently, an approach for nanoscale deformation has been developed that couples the atomistic and continuum approaches using Finite Element Method (FEM) and Molecular Dynamics (MD). However, this approach still has problems to connect two approaches because of the difference of basic assumptions, continuum and atomistic. To solve this problem, an alternative way is developed that connects the quasimolecular dynamics (QMD) and molecular dynamics (MD). In this paper, we suggest the way to make and validate the MD-QMD coupled model.

• Journal of Applied Biological Chemistry
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• v.56 no.1
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• pp.19-22
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• 2013

Plum (Prunus salicina L.) slices were dehydrated with red algae extract (RAE) at a concentration of 30% (w/w), and the dried samples were compared with maltodextrin (MD)-treated and hot-air dried samples in terms of physicochemical properties such as rehydration ratio, ascorbic acid, microstructure, and color. The rehydration ratios and colors of RAE-treated plum slices were better than those of MD-treated and hot-air dried samples. The ascorbic acid contents of RAE-treated samples were higher and their microstructures were finer than those of MD-treated or hot-air dried samples. These results suggest that plum slices can be dehydrated with RAE without loss of quality.

• Proceedings of the Korea Information Processing Society Conference
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• 2002.04b
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• pp.813-816
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• 2002

현재 인터넷은 IPv4(Internetworking Protocol, version 4)를 사용하고 있다. 하지만 데이터 통신은 1970년대에 IPv4가 나온 이래에 발전을 거듭하여 왔다. IPv4는 빠르게 발전하는 인터넷에의 요구를 수용하기 위해 IPv6가 제안되었고 현재 표준이 되었다. IPv6에서는 암호화와 인증옵션들은 패킷의 신뢰성과 무결성을 등을 제공한다. 인터넷에서의 정보보호는 인터넷을 구성하는 여러 계층에서 이루어 질 수 있지만, IPsec에서는 AH(Authentication Header)프로토콜과 IPsec ESP(Encapsulating Security Payload)프로토콜 두 가지의 암호 프로토콜이 사용되지만 AH에서는 HMAC를 이용한 HMAC-MD5나 HMAC-SHA-1 중 하나를 반드시 기본 인증 알고리즘으로 지원하여야 한다. 본 논문에서는 MD5를 이용한 HMAC-MD5를 기준으로 설계하였으며, Iterative Architecture과 Full loop unrolling Architecture의 두 가지 구조를 설계하였다.

• Bulletin of the Korean Chemical Society
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• v.18 no.5
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• pp.501-509
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• 1997

In recent papers[Bull. Kor. Chem. Soc. 1996, 17, 735; ibid 1997, 18, 478] we reported results of molecular dynamics (MD) simulations for the thermodynamic, structural, and dynamic properties of liquid normal alkanes, from n-butane to n-heptadecane, using three different models. Two of the three classes of models are collapsed atomic models while the third class is an atomistically detailed model. In the present paper we present results of MD simulations for the corresponding properties of liquid branched-chain alkanes using the same models. The thermodynamic property reflects that the intermolecular interactions become weaker as the shape of the molecule tends to approach that of a sphere and the surface area decreases with branching. Not like observed in the straight-chain alkanes, the structural properties of model Ⅲ from the site-site radial distribution function, the distribution functions of the average end-to-end distance and the root-mean-squared radii of gyration are not much different from those of models Ⅰ and Ⅱ. The branching effect on the self diffusion of liquid alkanes is well predicted from our MD simulation results but not on the viscosity and thermal conductivity.

• Korean Journal of Audiology
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• v.24 no.2
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• pp.53-60
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• 2020

Several novel animal models that represent the pathophysiological process of endolymphatic hydrops (ELH) of Meniere's disease (MD) have been developed. Animal models are important to identify and characterize the pathophysiology of ELH and to corroborate molecular and genetic findings in humans. This review of the current animal models will be useful in understanding the pathophysiology of and developing proper treatments for MD. Surgical animal models will be replaced by medication-induced animal models. Study models previously developed in guinea pigs will be developed in several smaller animals for ease of conducting molecular analysis. In this review, we provided updated resources including our previous studies regarding the current and desirable animal models for MD.

• Journal of Audiology & Otology
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• v.24 no.2
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• pp.53-60
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• 2020

Several novel animal models that represent the pathophysiological process of endolymphatic hydrops (ELH) of Meniere's disease (MD) have been developed. Animal models are important to identify and characterize the pathophysiology of ELH and to corroborate molecular and genetic findings in humans. This review of the current animal models will be useful in understanding the pathophysiology of and developing proper treatments for MD. Surgical animal models will be replaced by medication-induced animal models. Study models previously developed in guinea pigs will be developed in several smaller animals for ease of conducting molecular analysis. In this review, we provided updated resources including our previous studies regarding the current and desirable animal models for MD.