• Title/Summary/Keyword: MCPs

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Effects of Mahuang-Chuanwu(Mahwang-Cheonoh) Pharmacopuncture Solution on Adipocyte Differentiation and Gene Expression in 3T3-L1 Adipocytes (마황천오 약침액이 3T3-L1 지방세포 분화 및 유전자발현에 미치는 영향)

  • Kang, Kyung-Hwa
    • Korean Journal of Acupuncture
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    • v.31 no.4
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    • pp.168-178
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    • 2014
  • Objectives : Mahuang-Chuanwu(Mahwang-Cheonoh) Pharmacopuncture(MCP) has been used to treat obesity in Clinical Korean Medicine. MCP solution(MCPS) is also expected to have strong anti-obesity activities. However, little is known about the mechanisms of its inhibitory effects on adipocyte differentiation and lipogenesis. Methods : In the present study, we examined the effects of MCPS on differentiation and lipogenesis of 3T3-L1 adipocytes. To elucidate the mechanism of the effects of MCPS on lowering lipid content in 3T3-L1 adipocytes, we examined whether MCPS modulates the expressions of transcription factors to induce lipogenesis and adipogenic genes related to regulate the accumulation of lipids. Results : Our results showed that MCPS significantly inhibited differentiation and lipogenesis of 3T3-L1 adipocytes in a dose-dependent manner. MCPS suppressed the mRNA expressions of cytidine-cytidine-adenosine-adenosine-thymidine(CCAAT)/enhancer binding proteins ${\alpha}$($C/EBP{\alpha}$), C/EBP ${\beta}$, $C/EBP{\delta}$, and peroxisome proliferator-activated receptor ${\gamma}$($PPAR{\gamma}$) genes related to the induction of adipose differentiation. MCPS inhibited the mRNA expressions of adipose-specific aP2, adipsin, lipoprotein lipase(LPL), CD36, TGF-${\beta}$, and leptin genes related to the fat formation. MCPS downregulated the mRNA expressions of liver X receptor(LXR) ${\alpha}$ and fatty acid synthase(FAS) genes related to the induction of lipogenesis. In addition, MCPS reduced the production of adipocyte-induced pro-inflammatory cytokines. Conclusions : MCPS could regulate the accumulation of lipids and expression of adipogenic genes via inhibition of transcript factors related to induction of adipose differentiation.

A Study on the Relation between Cell morphology and Saturation condition in Gas-pellets MCPs (가스-펠릿 초미세 발포 사출 플라스틱 특성 연구)

  • Cha S. W.;Seo Jung-hwan
    • Journal of the Korean Society for Precision Engineering
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    • v.22 no.12 s.177
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    • pp.87-92
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    • 2005
  • In microcellular injection molding, gas supply system is needed. But, that device is very expensive to attach to the injection molding machines. So, new method is needed and gas-pellets MCPs is one of the solutions. In gas-pellets MCPs, there will be strange characteristics. In this paper, some characteristics are described on the view point of saturation pressure and saturation time.

Formation of cell under $1\mu{m}$ by quenching (Quenching을 이용한 $1\mu{m}$ 미만의 Cell 형성)

  • Lee B.H.;Cha S.W.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.06a
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    • pp.1420-1423
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    • 2005
  • Micro Cellular Plastics create a sensation at polymer industrial for lowering product cost & overcoming a lowering of mechanical intensity. Reduction of MCPs cell size increases the intensity of MCPs. This research based on the experiment about cell size reduction method. At this study, Quenching & Pressure foaming process are introduced to one of methods. Conclusion of study is that Quenching process is the simplest process for nano cell formation.

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A study for improve MCPs product surface about injection process (MCPs 사출 제품의 Gate 부근에 발생하는 Gas Flow Mark 개선을 위한 사출성형 공정 연구)

  • Hyun C.H.;Cha S.W.;Lee D.W.;Park Y.W.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.06a
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    • pp.1710-1714
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    • 2005
  • Micro Cellular Plastics create a sensation at polymer industrial for lowering product cost & overcoming a lowering of mechanical intensity. This research is surface quality research of MCPs product Through surface rough measurement. This experiment is carried out according to injection speed control with the surface rough & Product surface quality are searched

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Effect of Talc on cell density in foam processing with CO2 (Talc 함유량이 초미세 발포 셀-밀도에 미치는 영향)

  • 이보형;차성운
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2003.06a
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    • pp.1406-1409
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    • 2003
  • There is a great demand for reducing the amount of material used in mass-produced plastics parts, for material cost constitutes a large percentage of the total cost of 60%. It may be noted that the price of plastics is directly rotated to the price of petroleum. Material reduction therefore decreases the amount of oil needed for the manufacture of plastics and thus help conserve this natural resource. Therefore microcellular foaming process(MCPs) was studied for solving this problems alternatively in 1980's at M.I.T Until now in MCPs carbon dioxide gas was mainly used for microcellular foaming. Besides, Talc was used for reducing the price of plastics. Consequently, we must certificate using the Talc in MCPs according to contents of the Talc.

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The shrinkage characteristics of MCPs (Micro Cellular Plastics) (초미세 발포 플라스틱의 수축률 변화)

  • Seo, Jung-Hwan;Cha, Sung-Woon;Hyun, Chang-Hoon
    • Proceedings of the KSME Conference
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    • 2004.04a
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    • pp.1160-1164
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    • 2004
  • Generally in the case of parts used for precision products, tolerance of parts is very small. So inaccuate size of molding parts generates serious problems. Therefore, it's necessary to secure data about shrinkage on each condition or study about manufacturing process which reduces shrinkage. To apply MCPs to manufature of plastic product, this paper verifies how the amount of gas and Talc can affect to cell-morphology, and examines the relation between shrinkage and cell-morphology by using ASTM specimen formed by MCPs process.

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A study for PP resin High magnification MCPs Extrusion foaming (MCPs 압출 공법을 이용한 PP 수지의 고배율 압출 발포 연구)

  • Hyun C.H.;Cha S.W.;Kim H.B.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.10a
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    • pp.1046-1050
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    • 2005
  • Micro Cellular Plastics create a sensation at polymer industrial for lowering product cost & overcoming a lowering of mechanical intensity. There Is much development from injection molding pans but Extrusion parts is slow. This research is MCPs Extrusion parts, It is basis experiment for Process to make beads that is basis raw material of Package used most by shock mitigative of industry.

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The mechanical properties of 3D printed denture base resin incorporating essential oil microcapsules

  • Steve An;Jane Lesleigh Evans;Stephen Hamlet;Robert Matthew Love
    • The Journal of Advanced Prosthodontics
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    • v.15 no.4
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    • pp.189-201
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    • 2023
  • PURPOSE. The aim of this study was to investigate the mechanical properties of three-dimensional (3D) printed denture base resin incorporating microcapsules containing plant essential oils. MATERIALS AND METHODS. Denture base specimens containing up to 3% w/v essential oil microcapsule powders (MCPs), i.e., eucalyptus, geranium, lavender, menthol, and tea tree, in two resins (Detax and NextDent 3D+) were 3D printed using two printers (Asiga and NextDent 5100). The dispersion and interaction of the MCPs in the resin were assessed by SEM while the mechanical properties of the incorporated denture base including flexural strength (MPa), flexural modulus (MPa), Vickers hardness (VHN), and surface roughness (Ra) were also subsequently evaluated. Statistical analysis of any differences in mean values was determined using a two-way ANOVA with Tukey's post hoc testing (α = .05). RESULTS. The spherical shape of the MCPs was maintained during the mixing and polymerization/printing process. However, the Detax-Asiga group showed significant agglomeration of the MCPs even at the lowest MCP concentration levels (0.5% w/v). Overall, as the microcapsule concentration increased, the mean flexural strength decreased, though the menthol MCP groups remained compliant with the ISO standard. The flexural modulus and harness remained relatively unchanged, and the flexural modulus complied with the ISO standard regardless of the MCP concentration. Surface roughness increased with the addition of the MCPs but also remained below that required for clinical acceptance. CONCLUSION. Incorporation of microencapsulated plant essential oils into 3D printed denture base resin was successfully achieved. While incorporation negatively influenced flexural strength and surface roughness, little effect on flexural modulus and Vickers hardness was demonstrated.

Study of Sound Absorption & Transmission Characteristics for MCPs Foaming rate by Batch Process (MCPs Closed Cell 의 발포율에 따른 흡차음 특성 연구)

  • 이병희;차성운;강연준
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2004.10a
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    • pp.364-368
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    • 2004
  • Micro Cellular Plastics create a sensation at polymer industrial for lowering product cost & overcoming a lowering of mechanical intensity. This research based on the experiment of sound absorption & transmission characteristics inquire into acoustic property of Micro Cellular Plastics. This experiment clarify the change of cell foaming rate for foaming time and the change of sound absorption & transmission for foaming rate.

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Acoustical properties of Polypropylene MCPs in low frequency range (Polypropylene MCPs의 저주파대역 음향특성)

  • Lee B.H.;Cha S.W.;Kang Y.J.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.10a
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    • pp.828-833
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    • 2005
  • Micro Cellular Plastics create a sensation at polymer industrial for lowering product cost & overcoming a lowering of mechanical intensity. This research based on the experiment of sound absorption & transmission characteristics inquire into acoustical properties of Micro Cellular Plastics in low frequency range. TL difference of MCPs & Soild materials was defined as cell effect. Also, cell effect is expressed by sound reflection & sound absorption.

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