• Title/Summary/Keyword: MC21

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Perinatal outcomes according To chorionicity in Twin Gestations (쌍생아 임신의 융모막과 주산기 결과)

  • Choi, Eun-Jin;Yun, Hyun-Jin;Hyh, Jae-Won;Hong, Yong-Hong
    • Neonatal Medicine
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    • v.15 no.1
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    • pp.67-74
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    • 2008
  • Purpose : The purpose of this study was to assess the natural history and perinatal outcomes of twin gestations according to chorionicity. Methods : We retrospectively reviewed the medical records of 99 monochorionic (MC) and 206 dichorionic (DC) twin gestations delivered at Il Sin Christian Hospital in Busan between January 2002 and December 2007. The incidences of twin-to-twin transfusion syndrome (TTS) and selective intrauterine growth restriction (sIUGR), as well as perinatal morbidity and mortality, were evaluated. Results : MC twins had a lower gestational age (35.7 vs. 36.6 weeks, P=0.03) at birth and a higher incidence of intrauterine fetal loss (10% vs. 1.5%, P<0.001) than DC twins. The incidence of intrauterine fetal loss was higher in MC sIUGR than in DC sIUGR (19% vs. 2.5%, P=0.025) twins. The number of admissions to the neonatal intensive care unit (NICU; 31% vs. 16%, P=0.042), and the incidence of periventricular leukomalacia (7% vs. 0%, P=0.031), and respiratory distress syndrome with surfactant treatment (27% vs. 11%, P=0.049) were higher in MC than DC twins. The incidences of sIUGR and TTS were 21 and 9% among the MC twins. The incidences of intrauterine fetal loss were higher in MC twins with TTS [6 of 9 (67%)] or sIUGR [4 of 21 (19%)] than uncomplicated MC twins (P<0.001). The frequency of admission to the NICU (P=0.001), the length of hospital stay (P=0.033), the prevalence of periventricular leukomalacia (P=0.011), and intraventricular hemorrhage (P=0.007) were also higher in MC with TTS or sIUGR than in uncomplicated MC twins. Conclusion : The incidence of neonatal complications was higher in MC twins, especially those gestations complicated by TTS or sIUGR.

The Effects of Platelet- Derived Growth Factor-BB on the Expression of Bone Matrix Protein in the MC3T3-E1 Cells (MC3T3-E1 세포의 골기질 단백질 발현에 대한 혈소판유래성장인자-BB의 효과)

  • Kim, Myo-Sun;Lee, Jae-Mok;Suh, Jo-Young
    • Journal of Periodontal and Implant Science
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    • v.30 no.2
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    • pp.347-360
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    • 2000
  • Bone remodeling results from the combined process of bone resorption and new bone formation which is regulated in part by some of the polypeptide growth factors such as platelet derived growth factor(PDGF), which has been known to be an important local regulator of bone cell activity and participate in normal bone remodeling. This process includes strictly regulated gene expression of several bone matrix proteins such as type I collagen and osteopontin, a 44 kDa phosphorylated glycoprotein, which has important roles in bone formation. The purpose of this study is to evaluate the effecs of PDGF-BB on the mRNA expression of bone matrix protein, type I collagen and osteopontin, in MC3T3- E1 cell culture. Cells were seeded at $5{\times}10^5$ cells in 10 ml of minimum essential medium alpha(${\alpha}-MEM$) containig 10% fetal bovine serum, 10 mM beta glycerophosphate. 0.1, 1, 10 ng/ml PDGF-BB were added to the cells for the day 3, 7, 14, 21, 28 and cultured for 24 hours. Type I collagen cDNA, Hf677, and osteopontin cDNA were used as probes for northern blot analysis. Total cellular RNA was purified at indicated day and northern blot analysis was performed. The results were as follows : Type I collagen mRNA expressions were higher at the day 3 and 7, and lower in the day 14, 21 in the control groups. In the experimental groups, mRNA expressions were increased when 0.1 ng/ml PDGF-BB were added on the day 3, 7, 21, and decreased in dose-dependent manner on the day 14, decreased at all added dose on the day 28. Osteopontin mRNA expressions were highest in the day 21 groups and lowest in the day 14 groups in the control groups. Interesting results were shown in the day 14 and 21 groups. We found that osteopontin mRNA level was increased in dose dependent manner in the day 14 groups, and decreased dose dependent manner in the day 21 groups. In conclusion, PDGF-BB may have various control effects on type I mRNA expression in the growth and differentiation process of MC3T3-E1 cells and may have contrary regulatory effects on osteopontin mRNA expression. For examples, when the baseline level of osteopontin mRNA was low, as in the day 14, PDGF-BB up-regulated osteopontin mRNA expression in dose dependent manner, and when the baseline level was high as in the day 21, PDGF-BB down-regulated dose dependent manner. Thus, it may be useful for clinical application in periodontal regeneration procedure if further study were performed.

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The Correlation Between Forward Head Posture Used McKenzie Exercise and Plantar Pressure (멕켄지 운동 적용에 따른 전방머리자세와 족저압의 상관관계)

  • Han, Ji-Hoon;Kim, Jung-Hyun;Jung, Min-Keun;Ju, Tae-seong;Jeon, Jae-guk
    • The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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    • v.22 no.1
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    • pp.65-70
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    • 2016
  • Background: To determine the correlation Between forward head posture and plantar pressor in a McKenzie Exercise. Methods: This study had a cross-sectional design. There are included 20 participants with forward head posture. We measured the craniovertebral angle (CVA), cranial rotation angle (CRA) by image obtained digital camera and the plantar pressure, static balance using Gait Analyzer each before and after McKenzie Exercise. Results: There was negative correlation between CVA and CRA (p<.05). There was negative correlation between CVA and fore foot(p<.05). There was positive correlation between CRA and both fore foot (p<.05). There was negative correlation between CVA and static balance(p<.05). There was positive correlation between CRA and static balance (p<.05). Conclusions: There is a correlation between the change a mount of forward head position and plantar pressure in the McKenzie Exercise.

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Influence of moisture content on mold development in flue-cured tobacco during storage (저장중 황색종 잎담배의 수분 함량이 곰팡이 발생에 미치는 영향)

  • 조대휘;안동명;민영근;이완남;이경구;이상하
    • Journal of the Korean Society of Tobacco Science
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    • v.11 no.2
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    • pp.241-246
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    • 1989
  • Mold development on leaf tobacco(Flue-cured, var. NC 82) during the storage was examined according to the initial moisture content(MC) of the tobacco. The initial moisture content of the leaf tobacco was controlled as 12,14,16% after redrying. Those were packed in cardboard boxes and stored in a warehouse. Samples were taken monthly from June of 1988 through August of 1989 and were evaluated for mold development (colony count) and MC. The moisture content change in the leaf tobacco of 12, 14 and 16% initial MC was in the range of 11.1-13.3, 12.8-15.3 and 14.9-16.7% and the mean number of colonies from them were 1.4$\times$102, 1.0$\times$102, and 4.0$\times$102 colonies per gram of tobacco, respectively, however mold-damaged leaf tobacco other than the treatments was occasionally observed to have the colony number as high as 2.3$\times$105 colonies per gram of tobacco. In the meantime, the leaf tobacco was stored at 6 relative humidity levels at $25^{\circ}C$ in laboratory test. Leaf tobacco of 15.0-16.4% MC was maintained without the mold-damage after 80 days of storage whereas those of 19.9, 21.3, 25.5 and 27.1% MC became moldy after 50, 15, 11 and 6 days of storage, respectively.

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Radiolabelled Monoclonal Antibodies (McAb): An Alternate Approach to the Conventional Methods for the Assessment of Cardiomyocyte Damage in an Experimental Brain-Death Pig Model

  • Haider, Kh.H.;Stimson, W.H.
    • Archives of Pharmacal Research
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    • v.21 no.5
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    • pp.496-502
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    • 1998
  • The present study was carried out to determine the possible use of cTn-I in the cardiac myofibrillar architecture, as a potential target for in vivo radioimmunodetection of cardiac damage in a brain death pig model. Radioiodiantion of the anti-cTn-I 5F4 McAb was carried out by lactoperoxidase method. the percentage iodine incorporation achieved was 70-75%. The radioiodinated McAbs were purified on Sephadex G-25 column and characterised by Paper chromatography, Phast Gel electrophoresis and electroimmunoblotting. Radioiodinated anticTn-I 5F4 McAbs were employed alongside Pyrophosphate($Tc_{99m}$-PPi$) and $Thallium^{201}$ chloride($TI^{201}$) in 24 landrace pigs (brain-dead=18 & sham-operated=6). The percentage cardiac uptake of the radiolabelled antibody injected dose was significantly higher in the brain dead animals(0.196%) as compared to that of sham-operated animals (0.11%). Specific in vivo localization of radiolabelled McAbs in the infarcted cardiac tissue was confirmed by computer-aided reconstruction of 3-D images of the isolated heart. The preliminary results of the study revealed preferential uptake of radiolabelled antibody at the site of myocyte damage resulting from artificially induced brain death.

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A Check List and Key to the Tetranychod Mites (Acari: Chelicerata) of Korea (한국산 잎응애 상과의 목록 및 검색표)

  • 이원구;이정상
    • Animal Systematics, Evolution and Diversity
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    • no.nspc3
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    • pp.45-58
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    • 1992
  • Tetranychoid mites found from Korea until now are 42 species belonging to 12 genera, 2 families as follows: 1 Bryobia japonica Ehara et Yamada, 2. B. praetiosa Koch, 3. B. rubrioculus(Scheuten), 4. Petrobia latens(Muller), 5. Aponychus corpuzae Rimando, 6. A firmianae(Ma et Yuan). 7. Panonychus citri(McGregor), 8. P. ulmi(Koch), 9. Eotetranychus carpini Oudemans, 10. E. hicoriae(McGregor), 11. E. populi(Koch), 12. E. rubiphilus (Reck), 13. E. sexmaculatus (Riley), 14. E. smithi Pritchard et Baker, 15. E. tiliarium (Hermann), 16. E. uchidai Ehara, 17. Schizotetranychus bambusae Reck, 18. S. celarius(Banks), 19. S. leguminosus Ehara, 20. Oligonychus aceris(Shimer), 21. O. clavatus(Ehara), 22. O. hondoensis(Ehara), 23. O. ilicis(McGregor), 24. O. karamatus(Ehara), 25. O. orthius Rimando, 26. O. peridtus Pritchard et Baker, 27. O. shinkajii Ehara, 28. O. pustulosus (Ehara), 29. O. ununguis(Jacobi), 30. O. sp. 31. Tetranychus kanzawai Kishida, 32. T. phaselus Ehara, 33. T. truncatus Ehara, 34. T. urticae Koch, 35. T. vienensis Zacher, 36. Aegyptobia nothus Pritchard et Baker, 37. Pentamerismus taxi (Haller), 38. P. oregonensis McGregor, 39. Brevipalpus californicus(Banks), 40. B. lewisi McGregor, 41. B. obovatus Donnadieu, 42. Tenuipalpus zhizhilashviliae Reck. On the above species, a taxanomic key was made and ecological data including distribution and host plant are presented in this paper.

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A Study on Hybrid Trend upon Alexander McQueen's Work (Alexander McQueen의 패션작품에 나타난 하이브리드(Hybrid) 경향 분석)

  • Lee Hyo-Jin;Kim Ju-Yeon
    • The Research Journal of the Costume Culture
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    • v.13 no.2 s.55
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    • pp.300-313
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    • 2005
  • Hybrid trend of the 21st century is an important basis to express fashion Alexander McQueen is a representative designer of Hybrid trend which combines heterogeneous elements into oneconcept. Accordingly, this study distributed and analyzed Hybrid trend which was in Alexander McQueen's work like below. First, there was a racial Hybrid trend which combined different local culture in shared space of the world in his fashion work and he challenged to Westernized ideal beauty with new recognition and knowledge about beside countries of Western Europe which were considered as not important culture due to perceiving relative value of a pluralist society and created new way aesthetic consciousness. Second, he expressed a historical character of a combination of tradition and modern by his fashion work based on wide historical knowledge of a dress. He created a new line in contrast to the past with a perfect design through combination of the style from the tradition with the parody and displayed his own design world. Third, he treated instability and disorder from the interior essential dissolution, thus he had a cultural character which broke down the boundary of cultural genre and style. This attitude showed transformation of constructivism and deconstruction view, secession and distortion, mixture, duplication, secession and insert by his fashion work.

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Effects of Olibanum Extracts on the Activity and Differentiation of MC3T3-E1 Cells (유향 추출물이 MC3T3-E1 세포 활성 및 분화에 미치는 영향)

  • Han, Sang-Heon;Kim, Myoung-Dong;You, Seung-Han;You, Yong-Ouk;You, Hyung-Keun;Shin, Hyung-Shik
    • Journal of Periodontal and Implant Science
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    • v.31 no.2
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    • pp.287-298
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    • 2001
  • Recently, many natural medicines, which have advantage of less side effects and possibility of long-term use have been studied for their capacity of anti-bacterial, anti-inflammatory and regenerative potential of periodontal tissues. Olibanum has the effects to hemostasis, analgesic and anti-inflammatory, and it also has been traditionally used as a drug for the treatment of bone disease in oriental medicine. The purpose of the present study was to investigate the effects of Olibanum extracts on the activity and differentiation of MC3T3-E1 cells, alkaline phosphatase(ALP) synthesis, formation of bone nodules and expression of type I collagen of MC3T3-E1 cells. To examine the cellular activity, MC3T3-E1 cells were cultured with ${\alpha}-MEM(control)$ and each concentration of Olibanum for 2 days and 4 days. To compare the ALP synthesis, MC3T3-E1 cells were cultured with ${\alpha}-MEM(negative\; control)$, dexamethasone(positive control), and each concentration of Olibanum for 2 days and 4 days. To compare the bone nodule formation, MC3T3-E1 ells were cultured for 21 days, and to compare the type I collagen expression, MC3T3-E1 cells were cultured for 4 days. The cellular activity of MC3T3-E1 cells treated with $1{\mu}g/ml$ of Olibanum extracts was significantly increased at 4-day(p<0.05) to control. The activity of ALP in MC3T3-E1 cells treated with $1{\mu}g/ml$ Olibanum extracts was significantly increased at 4-day(p<0.05). All the experimental groups showed much more bone nodule formation than control groups. The group treated with $1{\mu}g/ml$ of Olibanum extracts was the highest bone nodule formation, and showed much more type I collagen expression than negative control. These results indicate that Olibanum extracts may be considered effective in the activity and differentiation of MC3T3-E1 cells.

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