• Bulletin of the Korean Chemical Society
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• v.34 no.2
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• pp.437-442
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• 2013

A new series of 4-(2-(substituted)pyridin-4-yl)-3-(3-methoxy-5-methylphenyl)-1H-pyrazoles (4a-f) and their 1,2-isoxazole analogues (5a-f) has been rationally designed, synthesized and screened against both ROS and MAPK14 kinases. Compounds 4b, 4c and 4e showed moderate inhibitions against both ROS and MAPK14 kinases. Compound 4e has showed the strongest inhibitions with IC50 values of 1.25 ${\mu}M$ and 3.00 ${\mu}M$ against ROS and MAPK14 kinases, respectively. A brief structure-activity relationship study and a molecular modeling study were made revealing a group of essential structural features for good kinase inhibitory activity within this new class of kinase inhibitors.

• Journal of Korean Ophthalmic Optics Society
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• v.20 no.1
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• pp.25-34
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• 2015

Purpose: To improve and guide the education policy for optician through a study about awareness of major in students from Dept. of Optometry. Methods: To define awareness of major in students from Dept. of Optometry, a survey was conducted by 91 male and 65 female students (50 freshmen, 48 sophomores, and 58 juniors). For the data analysis SPSS 18.0 was used and set the significant level as p<0.05 statistically. Results: The major awareness was evaluated with 4 sub-items, i.e. the awareness of satisfaction on curriculum, practical contents, society, and education courses. The results showed $3.39{\pm}0.68$, $3.26{\pm}0.65$, $3.59{\pm}0.75$, and $3.56{\pm}0.66$, respectively. The social awareness item recorded the highest score and practical contents item recorded the lowest. In general, awareness of major in males, higher grade students and students having a good mark was higher than the one in females, lower grade and students having a bad mark. In students who considered their aptitude and interest before the entrance of University, it turned out that the score was higher. Conclusions: It needs much efforts on developing professional confidence and strengthening the sense of belonging for the students from the Dept. of Optometry, not only by industrial but also academic circles.

• The Journal of the Korea Contents Association
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• v.12 no.10
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• pp.35-42
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• 2012

This study will research the possibility about the extension from aesthetic artwork of information visualization to performance area. In information visualization fields, the function of transmitting information is important factor. In addition, the relationship with the audience concerning immersion and interactivity is also significant. Therefore, if an artwork in information visualization can extend to a performance, this study proposes that it is necessary to consider what elements are needed to intensify sensorium for the audience in that artwork. In order to solve that question, this study introduces and analyzes the installation artworks by Ben Rubin and Mark hansen in 2001. From this case study, we suggest three elements-the performing self, the performing interface and the dramatic pattern-to amplify sensorium by hypermediacy for the audience. This research would contribute to the understanding aesthetic artworks based on information visualization in terms of performing arts.

• Journal of Arbitration Studies
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• v.16 no.1
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• pp.277-314
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• 2006

This article aims at analysing the reality of banks' liability resulting from the breach of contract on its part to keep the business secrecy with the supplier in the transferable credit, focusing on a English decision, Jackson v. Royal Bank of Scotland [2005] UKHL 3. In this case, the applicant, 'Econ', had purchased various varieties of pre-packed dog chews in bulk through 'Sam'(lst beneficiary) from 'PPLtd'(2nd beneficiary) in Thailand, using a transferable letter of credit issued by 'RBank'. 'Sam' charged a tremendous amount of mark-up on each transaction and it had not been disclosed to 'Econ', although the identity of 'PPLtd' was revealed to 'Econ' by various documents. However, 'RBank' made an unfortunate error to send an completion statement and other documents including 'PPLtd.'s invoice to 'Econ' instead of to 'Sam'. The effect of the Bank's error was to reveal to 'Econ' the substantial profit that 'Sam' was making on these transactions. CEO of 'Econ' was furious and, as a result, decided to cut 'Sam' out of its importing system and terminated their relationship. 'Sam' sued 'RBank' for damages to recover the loss of profits which could have been possibly made, if the information on the mark-up would not have been exposed to 'Econ'. The House of Lord held that 'RBank' was in breach of its duty of confidence, so 'Sam' was entitled to recover damages on a decreasing scale over 4 years, since there was no specific undertaking from the letter of credit.

• Archives of design research
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• v.11 no.2
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• pp.95-103
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• 1998

During design thinking and developing, its idea into the real world, and we are under pattern recognition and gestalt principles of perceptual organization. Generally originality is a part of creativity which consists an integral factor of the designing. This is a study on the measure system for an ability of originality in design. It is reorganized that the OTLD(Originality Test of Line Drawing) is a measuring system for personal originality. In order to catch the development the thoughts, we presented 10 picture planes as stimuli (each picture plane contained 3-18 dots), recorded the tape displaying eye-mark trajectories and outputting the trajectories with EMR(Eye Mark Recorder), then found the process of visual sensation and perception. From the results of this study, we examined the relationships between connections and complexity of the objects on the picture plane, which could be transformed into some objective measuring parameters. We would suggest this OLTD as a measurement system for an ability of originality in design fields, but we couldn't find any reliability and validity for fine art fields.

• Journal of the Korean Society of Fashion and Beauty
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• v.4 no.3 s.9
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• pp.5-12
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• 2006

Make-up illustration is a field of creativity with visible creative and artistic values; its ultimate functions include communication of information, artistic expression, and recording. Establishing the make-up illustration education environment for the twenty-first century, there is an urgent need for research and development of professional curricula for basic art education and illustration education. It is extremely important for educators and institutions teaching make-up illustration to recognize that training of highly creative and professional beau designers through systematic educational structures is the ultimate foundation for enhancing competitiveness of the beauty industry despite the present reality that there are insufficient studies and publications on beauty illustration and that there is lack of illustration lecturers and artists equipped with professional beauty knowledge. Therefore, this study was conducted to research and analyze offering of illustration subjects by 160 beauty-related vocational schools and 16 4-year undergraduate colleges in the make-up field, which is the field with most creative art activities among the three representative beauty majors, namely make-up, hair, and skin. Education of make-up illustration must not remain as simple short-term education. The curricula must be specialized for providing solid foundation of basic majors. In terms of education content, strong emphases must be made for original and creative mark-up designs as well as purposes, functions, and necessity of make-up design and illustration. The curricula must include systematic, logical and artistic elements. Through the course of this study, which researched, analyzed and proposed measures for education content of make-up illustration, it was found that make-up illustration is the most appropriate subject that fulfills both the ultimate education objectives of beauty colleges and the demand by the society for beauty professionals. It is hoped that make-up illustration is emphasized and recognized for its importance and necessity as an education subject so that similar basic major subjects will further be researched and developed for specialized education.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.8 no.1
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• pp.123-132
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• 1997

The purpose of this paper is to introduce the current trends of British Music Therapy and its effectiveness as a therapeutic intervention for the autistic children. This paper consists of two parts；Part one will provide a general picture of music therapy by looking at its fundamental concepts and therories. Part II(two case studies) will illustrate the actual processes of music therapy which can engender a therapeutic relationship between the therapist and the autistic child. Through the first case study of Charlie, a 3 year and 9 month non-verbal autistic boy, we shall see how music therapy facilitates both non-verbal and verbal communication and a form of pretend play. The second case of Mark, a 10 year old autistic boy with complex emotional, behavioural and learning difficulties who had been sexually abused in the past, presents how the therapist’ acceptance of the child’ being and the shared experience of music therapy enable the child to express his difficulties and to develop the awareness of self and others. By exploring both musical and interpersonal aspects of music therapy, this gives an in depth examination of therapeutic processes. In order to clarify clinical procedure, this paper is viewed in musical, developmental and psychodynamic perspectives. To ensure confidentiality, the clients will be referred to by alter-native forenames.

• Journal of the Korean Society for Library and Information Science
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• v.28
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• pp.23-70
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• 1995

This study is to survey the present book numbers used in Korean libraries. to analyze their problems. and to suggest improvement in the book numbers. As the results of the survey several suggestions are derived as follows. 1. The education to the librarians about the kinds and the application methods of the book numbers used in Korean libraries should be sufficiently offered. 2. The present book numbers used should be expanded in detail for avoiding the duplication of the call numbers. Also when book numbers are assigned. shelf list cards should be examined one by one not to give the same number. If the book numbers are overlapped in the state not to expand further. libraries should establish a detailed expansion rules according to their respective situation and maintain it consistently. However, it is impossible for libraries operating open stack systems to arrange books on the shelves in call number sequence, therefore libraries can solve the problems as they accept duplication cases. 3. Since the object word of main mark IS a heading In main entry, we must apply cataloging rules to it closely. 4. For expanding book numbers widely it is desirable that the subsidiary mark of the book numbers which is the most prevalent in general and will be the most preferable In the future through the survey should be added and be provided. 5. The book numbers used being changed, we are to assign new book number leaving former materials as they are at the point of adopting a new book number. So aged materials are stored in a repository or on a compact shelf in the stack, will be discarded or weeded according to subjects after a certain period of time. 6. With library automation bringing together all the books of an author in a particular subject or in a particular form and avoiding completely duplication in open stack systems are meaningless. Rather than chronological book numbers, distinguishing clearly new materials from aged materials and controlling the stack spaces mechanically and effectively, can be regarded as the most modern and future-oriented of all the book numbers.

• Management & Information Systems Review
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• v.24
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• pp.97-124
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• 2008

This study aimed to explore how the involvement of environment influenced eight subjects group. Thus, experiment was performed to clarify the role that the attitude of university student consumer plays in the communication process depending on the level of engagement of consumer in the environment and method to raise donation for preservation of environment. Analyzing as per the type of appeal, the mark in altruistic appeal type was higher in all variables than egoistic appeal type. Finally, checking the average mark of each variable as per the condition of donation, the value in unconditional donation was higher than in all variables than conditional donation. It was found 3 groups composed of 2 groups with high level of environmental engagement and 1 group with low level of environmental engagement were suitable to double mediation model among the 8 experimental groups. The group where double mediation model best corresponds than any other group was high level related to environment and the group that contacts altruistic appeal and the message in the form of conditional donation. It was also found that the group that has low level of environmental engagement and contacts egoistic appeal type and conditional donation shows the group that corresponds to double mediation model in the second place among the 8 groups. Finally, it was found that the group that has high level of environmental engagement and is stimulated by altruistic appeal and unconditional donation corresponds to double mediation model. Depending on the condition of message stimulation, unconditional donation is found to better correspond to double mediation model than conditional donation. However, opposite phenomena is observed when the level of environmental engagement is high and appeal type is egoistic. Namely, it was found that conditional donation better corresponds to double mediation model than unconditional donation.

• Journal of the Korean association of regional geographers
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• v.20 no.3
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• pp.300-314
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• 2014

The study is to systematically review "DaedongYeojiJeondo", the mid-sized wood block map of Chosun to shed light on the cartographic characteristics not discovered by previous studies. First it was discovered that Kim Jung-ho is the developer of the map as the distance information from Seoul to towns is identical with the information on "Daedong Jiji" the manuscript map drawn by Kim Jung-ho himself (assumed to live from 1804~1866) that is still remaining unfinished. Second, the information Kim Jung-ho wanted to specify most precisely and specifically was distance from Seoul to towns and for this purpose he invented unique symbols for towns in tiny size on the map. Third, in selecting information to mark on the map including road network, street information, mountain routes and streams and location of islands, "DaedongYeojiJeondo" is not just a simple smaller copy of "DaedongYeojido" but an independent creative work as it is much different in many aspects of quality. Forth, but still "DaedongYeojiJeondo" and "DaedongYeojido" have something in common in the fact both of them tried to mark land and mountain routes and streams most precisely and specifically.