• 한국지역사회생활과학회지
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• 제23권3호
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• pp.339-346
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• 2012

The quality characteristics of kochujang added with additives of different ratios of rice-nuruk (at 1:0.7, 1:1.0, 1:1.3) were studied. The kochujang was stored for 8 weeks at $20{\pm}3^{\circ}C$. The brix tended to increase by increasing mixing ratio of rice-nuruk in all treatments. It increased rapidly up to 4 weeks fermentation and then showed a slight change after 6 weeks. The more mixing ratio of rice-nuruk increased, the more salinity of samples decreased. The initial pH value of kochujang was 5.08-5.10., however, the pH value decreased to 4.82-4.83 after an 8 weeks of storage period. The initial acid value was 0.66-0.68 and increased from 0.66-0.68 to 0.87-0.89. It had slight reduction phenomenon in the sixth week. As the aging period passed, chromaticity such as $a^*$- and $b^*$-values decreased gradually except for $L^*$-value. The moisture content of samples decreased gradually by adding rice-nuruk. but increased by passing an aging period. The initial amino nitrogen content of sample was 304-315 mg%. It increased to 399-442 mg% during the aging period. As the aging period passed, the total cell number increased from 6.81 log CFU/mL to 7.01 log CFU/mL in the fourth week and then steadily decreased to 6.66 log CFU/mL in the eight week. Results of sensory evaluation show that, as more rice-nuruk was added, the kochujang received a lower mark. There was no significant difference in flavor in all treatments. Color and sweetness with increasing amounts of rice-nuruk showed the lowest score. Saltiness rice-nuruk at the ratio of 1:1.0 was the highest at 6.22 points. Texture scores decreased with increasing amounts of the rice-nuruk Based on these results, the overall acceptability of the 1:0.7 rice-nuruk treatment which received the highest score is considered excellent.

• 대한토목학회논문집
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• 제31권1D호
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• pp.65-72
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• 2011

고속도로 분기부 연결로상에서는 연속되는 유출형태가 나타나게 되어, 주행상의 안전성을 고려한 1차, 2차 분류지점 간 적정 이격거리(L)를 확보하는 것은 매우 중요한 사항이다. 본 연구에서는 현행 도로설계 지침에서 제시한 240m라는 동일한 설계기준을 적용하는 대신에, 동 구간에서 운전자에게 필요한 인지반응시간과 차로변경시간을 고려한 적정 이격거리를 산정하는 방식을 제안하였다. 특히 인지반응시간과 관련하여 정지시거 계산에 활용되는 기존의 2.5초와 더불어 기하구조 상의 특성을 고려한 판단시거 계산에 활용되는 보다 긴 인지반응시간을 추가적으로 고려하였다. 더불어 적정 이격거리 산정의 타당성을 확인하기 위해 고속도로 분기점 중 사고가 잦은 네 개의 분기점을 대상으로 교통사고 발생현황을 조사하여, 본 연구에서 검토한 적정 이격거리 산정방법을 적용하여 최소 이격거리를 도출하여 보았다. 연구 결과, 현재의 기준치가 정지시거를 중심으로 할 때는 충분한 최소 이격거리를 제시하고 있지만 판단시거를 중심으로 할 때는 충분하지 못하다는 점을 확인할 수 있었다. 사고가 잦은 현장에서 조사한 차량들의 실제 주행속도가 설계속도와 비교해 월등히 높은 점을 감안한다면, 지침에서 제시하는 것과 같은 획일적인 이격거리의 적용보다는 예상되지 못한 상황을 가정하여 적정 이격거리를 구하게 되는 판단시거를 중심으로 한 이격거리 계산과 설계가 오히려 더 설득력 있을 것으로 사료된다.

• Biomolecules & Therapeutics
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• 제25권4호
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• pp.374-382
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• 2017

Autism spectrum disorder (ASD) remains unexplained and untreated despite the high attention of research in recent years. Aside from its various characteristics is the baffling male preponderance over the female population. Using a validated animal model of ASD which is the telomerase reverse transcriptase overexpressing mice (TERT-tg), we conducted ASD-related behavioral assessments and protein expression experiments to mark the difference between male and females of this animal model. After statistically analyzing the results, we found significant effects of TERT overexpression in sociability, social novelty preference, anxiety, nest building, and electroseizure threshold in the males but not their female littermates. Along these differences are the male-specific increased expressions of postsynaptic proteins which are the NMDA and AMPA receptors in the prefrontal cortex. The vGluT1 presynaptic proteins, but not GAD, were upregulated in both sexes of TERT-tg mice, although it is more significantly pronounced in the male group. Here, we confirmed that the behavioral effect of TERT overexpression in mice was male-specific, suggesting that the aberration of this gene and its downstream pathways preferentially affect the functional development of the male brain, consistent with the male preponderance in ASD.

• Molecules and Cells
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• 제43권4호
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• pp.360-372
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• 2020

The basal ganglia network has been implicated in the control of adaptive behavior, possibly by integrating motor learning and motivational processes. Both positive and negative reinforcement appear to shape our behavioral adaptation by modulating the function of the basal ganglia. Here, we examined a transgenic mouse line (G2CT) in which synaptic transmissions onto the medium spiny neurons (MSNs) of the basal ganglia are depressed. We found that the level of collaterals from direct pathway MSNs in the external segment of the globus pallidus (GPe) ('bridging collaterals') was decreased in these mice, and this was accompanied by behavioral inhibition under stress. Furthermore, additional manipulations that could further decrease or restore the level of the bridging collaterals resulted in an increase in behavioral inhibition or active behavior in the G2CT mice, respectively. Collectively, our data indicate that the striatum of the basal ganglia network integrates negative emotions and controls appropriate coping responses in which the bridging collateral connections in the GPe play a critical regulatory role.

• 아시안잔디학회지
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• 제23권1호
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• pp.61-76
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• 2009

본 연구는 골프장의 적정 코스관리 비용을 구명하고 국내 골프장 29개의 홀당 내장객당 비용과 골프장 8개의 항목별 및 장소별 비용을 분석한 결과는 다음과 같다. 1. 홀 당 내장객이 증가할수록 홀 내장객당 비용이 감소하는 경향을 보여 주었다. 2. 골프장 코스관리 비용을 결정하는 인자는 연 내장객, 코스면적, 운영형태, 코스자동화 시설 등이다. 3. 골프장의 단위면적당 코스관리 비용은 869원이었다. 4. 8개 골프장의 홀 당 평균 코스관리 비용은 44,325,000원이었다. 5. 골프장 코스관리 비용 중 인건비 비중이 가장 높았으며 인건비중 그린의 볼마크 보수 인건비가 홀 당 평균 4,163,000원 (26%)으로 가장 높았다. 6. 골프장 총 코스면적의 평균 30% 정도를 차지하는 페어웨이에 사용되는 재료비가 총 재료비용의 $22%{\sim}44%$이며 그중 수입비료, 병충해 방제농약, 배토용 모래등의 구입비가 가장 많았다. 7. 총 코스면적의 평균 2% 정도를 차지하는 그린에 사용되는 재료비가 총 재료비용의 $28%{\sim}36%$이며, 입자형 비료, 미량원소비료, 토양개량제 등의 수입 제품으로 인해 그 구입비가 가장 많았다. 8. 농약 대용으로 미생물, 키토산 등의 친환경제제가 대신 사용된 경우 비용에서는 큰 차이가 없었다.

• 한국컴퓨터정보학회논문지
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• 제16권12호
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• pp.1-10
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• 2011

내장형 시스템의요구사항이 복잡해짐에 따라 내장형 소프트웨어의 신뢰도를분석하기 위한 도구가 요구되고있다. 소프트웨어의 신뢰도를 분석하는 방법으로는 확률적 모델링을 이용하는데, 다수의 디바이스를 제어하는 내장형 소프트웨어에 적용하기 위해서는 내장형 소프트웨어에 특성화 시킬 필요가 있다. 또한, 기존의 신뢰도 분석 도구는 각 상태간의 전이 확률을 다른 방법으로 측정해야 하고, 한 번 작성한 모델에 대해 재사용을 고려하고 있지 않는다. 본 논문은 내장형 소프트웨어의 신뢰도를 분석하기 위해 내장형 소프트웨어 마르코프 체인 모델과 단위 테스팅 도구를 이용한 신뢰도 분석 도구를 제안한다. 내장형 소프트웨어 마르코프 체인 모델은 신뢰도 분석 방법으로 많이 사용되고 있는 마르코프 체인 모델을 내장형 소프트웨어에 특성화 시킨 모델이다. 그리고 단위 테스팅 도구는 내장형 소프트웨어의 개발환경에 적합한 호스트/타겟 구조를 가지고 있다. 제안하는 도구는 신뢰도 분석을 위해 단위간 전이 확률을 단위 테스트 결과로부터 자동으로 측정하여 기존의 도구보다 용이하게 신뢰도를 분석할 수 있다. 그리고 소프트웨어 모델을 XML 기반의 문서로 표현하여 단위 테스팅 도구가 업데이트 시킨 테스트 결과를 바로 적용할수 있고, 웹 기반의 인터페이스와 SVN 저장소를 이용하여 다수의 개발자가 쉽게 접근할 수 있는 장점을 갖는다. 본 논문에서는 예제를 이용하여 신뢰도의 분석을 보이고 신뢰도 측정에 유용함을 보인다.

• 디지털융복합연구
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• 제15권8호
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• pp.103-114
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• 2017

본 연구는 최근 성장 중인 온라인 신선식품 분야에서 서비스를 제공 중인 주요 기업들의 현황을 파악하고, 경쟁력과 문제점을 실제 이용자에 대한 설문을 통해 분석하여 향후 사업방향을 제시하고자 했다. 현재 온라인으로 신선식품을 판매 중인 기업들의 현황과 시장상황을 살펴보기 위해 신선식품을 판매하고 있는 온라인 쇼핑몰을 대상으로 하여 BCG매트릭스 분석을 실시하였다. 또한 IPA분석을 활용하여 실제 구매자가 인식하는 신선물류에 대한 만족도와 중요도를 측정하여 연구결과를 도출했다. 먼저 BCG매트릭스를 적용한 결과, 쿠팡을 제외한 나머지 기업들은 새로운 성장방안이 필요하다는 점을 알 수 있었다. 한편 IPA분석 결과에서 나타난 비우선순위와 과잉영역에 소모되는 비용을 최소화 시키고, 유지 강화영역과 중점투자영역에 대해 투자함으로 신선물류시장에서 경쟁력을 확보해야한다는 시사점을 제시했다. 본 연구는 온라인 신선식품 주요 기업들을 대상으로 하여 보편적인 개선방안을 제시하였으나 향후 연구에서는 각각의 기업들을 대상으로 분석 표본을 확대 및 세분화하여 표본에 따른 경쟁력 제고방안 연구가 필요하다고 사료된다.

• Safety and Health at Work
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• 제8권2호
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• pp.198-205
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• 2017

Background: There are a million ragpickers in India who gather and trade recyclable municipal solid wastes materials for a living. The objective of this study was to examine whether their occupation adversely affects their immunity. Methods: Seventy-four women ragpickers (median age, 30 years) and 65 age-matched control housemaids were enrolled. Flow cytometry was used to measure leukocyte subsets, and leukocyte expressions of $Fc{\gamma}$ receptor I (CD64), $Fc{\gamma}RIII$ (CD16), complement receptor 1 (CD35) and CR3 (CD11b/CD18), and CD14. Serum total immunoglobulin-E was estimated with enzyme-linked immunosorbent assay. Results: Compared with the controls, ragpickers had significantly (p < 0.0001) higher levels of CD8-T-cytotoxic, CD16+CD56+natural killer, and CD4+CD45RO+memory T-cells, but depleted levels of CD19+B-cells. The percentage of CD4+T-helper-cells was lower than the control group (p < 0.0001), but their absolute number was relatively unchanged (p = 0.42) due to 11% higher lymphocyte counts in ragpickers. In ragpickers, the percentages of CD14+CD16+intermediate and CD14dim CD16+nonclassical monocyte subsets were elevated with a decline in CD14+CD16-classical monocytes. The expressions of CD64, CD16, CD35, and CD11b/CD18 on both monocytes and neutrophils, and CD14 on monocytes were significantly higher in ragpickers. In addition, ragpickers had 2.7-times more serum immunoglobulin-E than the controls (p < 0.0001). After controlling potential confounders, the profession of ragpicking was positively associated with the changes. Conclusion: Ragpicking is associated with alterations in both innate (neutrophils, monocytes, and natural killer cell numbers and expression of complement and $Fc{\gamma}$ receptors) and adaptive immunity (numbers of circulating B cells, helper, cytotoxic, and memory T cells).

• Nuclear Engineering and Technology
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• 제45권6호
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• pp.731-744
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• 2013

Energy security is a topic of high importance to many countries throughout the world. Countries with access to vast energy supplies enjoy all of the economic and political benefits that come with controlling a highly sought after commodity. Given the desire to diversify away from fossil fuels due to rising environmental and economic concerns, there are limited technology options available for baseload electricity generation. Further complicating this issue is the desire for energy sources to be sustainable and globally scalable in addition to being economic and environmentally benign. Nuclear energy in its current form meets many but not all of these attributes. In order to address these limitations, TerraPower, LLC has developed the Traveling Wave Reactor (TWR) which is a near-term deployable and truly sustainable energy solution that is globally scalable for the indefinite future. The fast neutron spectrum allows up to a ~30-fold gain in fuel utilization efficiency when compared to conventional light water reactors utilizing enriched fuel. When compared to other fast reactors, TWRs represent the lowest cost alternative to enjoy the energy security benefits of an advanced nuclear fuel cycle without the associated proliferation concerns of chemical reprocessing. On a country level, this represents a significant savings in the energy generation infrastructure for several reasons 1) no reprocessing plants need to be built, 2) a reduced number of enrichment plants need to be built, 3) reduced waste production results in a lower repository capacity requirement and reduced waste transportation costs and 4) less uranium ore needs to be mined or purchased since natural or depleted uranium can be used directly as fuel. With advanced technological development and added cost, TWRs are also capable of reusing both their own used fuel and used fuel from LWRs, thereby eliminating the need for enrichment in the longer term and reducing the overall societal waste burden. This paper describes the origins and current status of the TWR development program at TerraPower, LLC. Some of the areas covered include the key TWR design challenges and brief descriptions of TWR-Prototype (TWR-P) reactor. Selected information on the TWR-P core designs are also provided in the areas of neutronic, thermal hydraulic and fuel performance. The TWR-P plant design is also described in such areas as; system design descriptions, mechanical design, and safety performance.

• 자원환경지질
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• 제9권1호
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• pp.1-11
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• 1976

It is believed that geological survey, drilling and geophysical survey which was carried out on Tertiary deposits in Pohang is a valuable but through the studying of many Tertiary sediments in Japan discovered many questions on analysis of final report prepared by National geological survey. The main reason is: 1. The seismic sound velocity which have regulated in the final report prepared by geological survey for Tertiary deposits in Pohang was 1,500-2,000m/sec in spite of oil bearing sediments of same age in Japan are 2,000-3,800m/sec. These may means the requirement of reconsideration of seismic velocity for Tertiary deposits in Pohang and required to have a dipper drilling. 2. Stratigraphically, geophysically, and paleontologically, the Tertiary deposits in Pahang land area is similar with that of Nishiyama-Hunakawa formations of Akita oil field in Japan. Nishiyama-Hunakawa formation is the main oil bearing formation in Japan. 3. Those valcanic rock including andestitic rock and liparitic rock which have extensively distributed over either at land area or at sea bottom, assumed by geological survey as the base of Tertiary sediments. But in case of Japan many oil bearing deposits are in over laid by these kind of volcanic rock. Therefore a possible of same condition with Japan is presumable on Tertiary sediments in Pohang. 4. It is believed that the Tertiary sediments of land area in Pohang is the extension of offshore basin but is wandering that the final report submitted by geologic survey have not remain any word on report of ECAFE discribed so much problematics as followed: A. Although it was assumed that no great thickness exceeding 1,000 meters, or major structures would be encountered in the Tertiary offshore sequence, it was hoped that shallow hydrocarbon deposits might be found, because these sediment are lithologically similar to those of the same age in the producing area of the northwest Honshu region of Japan where hydrocarbon are extracted from depths of only 500 to 600 meters. B. Four possible hydrocarbon trap conditions are represented in the survey area: anticlinal folds, faults, pinch outs, along the igneous basement and lateral facies changes. C. Most of the prime possible reservoir area are beyond the 50 meter water depth mark, except for the structures in Yonil Bay. D. Despite the shallowness of the offshore basin, sufficient trap condition exist in the area to warrant further exploration for hydrocarbon. 5. All of the problems mentioned above have gave us a strong reasons to have us hesitating to make a final conclusion on Tertiary problems in Pohang, before to have a drill to a depth to 3,000 meters or more whatever it is the Tertiary or a Mesozoics below 1,000 meters.