• Proceedings of the International Microelectronics And Packaging Society Conference
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• 2002.09a
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• pp.33-49
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• 2002

$\Box$ LTCC/LTCC-M technologies are a cost-effective SOP technology $\Box$ LTCC/LTCC-M materials have good RF characteristics and the materials can be used as excellent substrates for high band width applications $\Box$ Reliability of LTCC/LTCC-M package or module can be greatly improved by embedded passive technology and CTE control of the substrates $\Box$ To expand the application area, more development is needed in realization of embedded passives with tight tolerance

• Proceedings of the Korea Institutes of Information Security and Cryptology Conference
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• 1991.11a
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• pp.49-57
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• 1991

Several variants of the Diffie-Hellman public key distribution are examined, and a simple and relatively secure public key distribution protocol is introduced. Using a normal basis of GF(2$^{m}$ ), this protocol is implemented, and simulated in software. A program is developed, whereby a normal basis is effectively searched for fast multiplication in GF(2$^{m}$ ).

• KCID journal
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• v.7 no.2
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• pp.49-56
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• 2000

A hydraulic model study have been carried out on roughness coefficient of corrugated helical steel pipe. The study was performed in the 0.6m wide flume of Hydraulic Laboratory for the pipe diameter of 0.6m and 1.6m. Additional study was performed in 2m wi

• Korean Chemical Engineering Research
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• v.54 no.1
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• pp.140-144
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• 2016

In this study, the physical factors for amylase production by Arthrobacter sp. were optimized using response surface methodology(RSM). Antarctic microorganism Arthrobacter sp. PAMC 27388 was obtained from the Polar and Alpine Microbial Collection(PAMC) at the Korea Polar Research Institute. This microorganism was confirmed for the excretion of amylase with Lugol's solution. The amylase activity was after flask culture was as low as 1.66 mU/L before optimization. The physical factors including the inoculum volume, the initial culture pH, and the medium volume were chosen to be optimized for the enhanced amylase production. The calculated results using RSM indicate that the optimal physical factors were 2.49 mL inoculum volume, 6.85 pH and 42.87 mL medium volume with a predicted amylase production of 2.84 mU/L. The experimentally obtained amylase activity was 2.50 mU/L, which was a 150% increase compared to the level before optimization.

• Journal of the Korean Geotechnical Society
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• v.34 no.4
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• pp.49-55
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• 2018

A pre-load of bracing was imposed to prevent the horizontal displacement on the strut of the braced wall adjacent to the building during the ground excavation. For this purpose, large scale model tests were conducted, without and with pre-load on braced wall. Adjacent building load was also imposed in different locations, that were 0 m, 1D, 2D on ground surface. In this study, model tests in 1:10 scale were performed in real construction sequences, and adjacent building was 12 m in width and the size of model test pit was 2 m in width, 6 m in height, and 4 m in length. As a result, it was found that the stability of the existing building adjacent to the braced wall within Rankine's active zone could be greatly enhanced when the horizontal displacement of the braced wall was reduced by applying a pre-load. which was larger than the designated axial force on the strut of the braced wall.

• Korean Journal of Environment and Ecology
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• v.34 no.2
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• pp.115-120
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• 2020

This study investigated the dominant species and the population variation of the ant species, an indicator species of biodiversity, to obtain basic data on the changes of population according to the future climate change. The survey period was from June to September 2013, and we investigated the distribution of ants by square irradiation method (10m × 10m) using traps. The survey in each altitude identified a total of 14 species of 11 genera in 3 subfamilies and collected 15,466 individuals. We confirmed the distribution of 4,548 individuals of 13 species at low altitude (700m), and the dominant species was Aphaenogaster japonica (49.9%). At the middle altitude (900m), we collected 9,129 individuals of 8 species, and the dominant species was Pheidole fervida (57.7%). At high altitude (1,100m), we identified 1,789 individuals of 10 species, and Myrmica kotokui (43.3%) was the dominant species. It was confirmed that Aphaenogaster japonica, Nylanderia flavipes, and Pheidole fervida were widely distributed throughout the altitudes.

• Journal of Veterinary Clinics
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• v.17 no.2
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• pp.388-394
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• 2000

이 실험은 소형견종에 대한 정상 SEPs의 범위를 알아내기 위해 실시되었다. 임상증 상이 정상인 28두를 대상으로 자극점에서 channel 1 까지의 Pl(LPI), channel 1까지의 Nl (LN1), 자극점에서 channel 2가지의 Pl(TP1), channel 2까지의 N1(TNI)의 절대잠복기와 LP1-TN1` 의 파간잠복기를 알아내기 위해서 실시하였다. 이번 실험에서 LPI, LNI, TPI, TNI의 절대잠복기 (absolute latency)의 평균값은 2.69$\pm$0.31 msec, 4.91$\pm$0.49m/sec, 4.64$\pm$0.39 msec, 5.21$\pm$0.42 msec 띠었다. LP1과 TN1 사이의 파간절대잠복기의 핑균값은 2.52$\pm$7.19 msec 이었다. 측정 치들을 속도로 변환하였을 경우 다음과 같았다. 측, LPI, LNI. Tfl, TNI 그리고 LP1-TN1 에서의 속도의 평균값은 각각 93.11$\pm$ 8.58 m/sec, 50.99$\pm$ 5.36m/sec. 80.18$\pm$ sec, 71.31$\pm$4.79m/sec그리고 49.50$\pm$3.58m/sec 이었고. 71.66m/sec, 37.79m/sec, 65.75m/ sec, 59.33 m/sec, 40.55m/sec 의 최저속도를 초과하였을 때 정상범위로 간주하였다. LPI, LNI, TPI,TN1까지의 절대잠복기와 자극전극에 시 측정전극가지의 거리 사이에는 상관관계가 있었다 LP1, LN1, TP1, TN1의 상관계수는 각각 0.621, 0.494. 0.577,0.618 이었다 요추에서 기록된 SEPs갈은 LP1의 상관계수가 LN1 보다 높았으며 흉추에서 기록된 SEPs값은 TN1의 상관계수가 TP1보다 높았다. LP1과 TN1의 파간잠복기와 channel 1과 2의 거리차이와의 상관계수는 0.571이다. 따라서 LPI, LNI. TPI, TNI그리고 LPI-TNI 들의 최저속도를 이용 하여 척수 손상 여부를 판단할 수 있다고 생각된다.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.8
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• pp.3451-3455
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• 2014

Background: The serum carcinoembryonic antigen (CEA) level can reflect tumor growth, recurrence and metastasis. It has been reported that epidermal growth factor receptor (EGFR) mutations in exons 19 and 21may have an important relationship with tumor cell sensitivity to EGFR-TKI therapy. In this study, we investigated the clinical value of EGFR mutations and serum CEA in patients with non-small cell lung cancer (NSCLC). Materials and Methods: The presence of mutations in EGFR exons 19 and 21 in the tissue samples of 315 patients with NSCLC was detected with real-time fluorescent PCR technology, while the serum CEA level in cases who had not yet undergone surgery, radiotherapy, chemotherapy and targeted therapy were assessed by electrochemical luminescence. Results: The mutation rates in EGFR exons 19 and 21 were 23.2% and 14.9%, respectively, with the two combined in 3.81%. Measured prior to the start of surgery, radiotherapy, chemotherapy and targeted treatment, serum CEA levels were abnormally high in 54.3% of the patients. In those with a serum CEA level <5 ng/mL, the EGFR mutation rate was 18.8%, while with 5~19 ng/mL and ${\geq}20ng/mL$, the rates were 36.4% and 62.5%. In addition, in the cohort of patients with the CEA level being 20~49 ng/mL, the EGFR mutation rate was 85.7%, while in those with the CEA level ${\geq}50ng/mL$, the EGFR mutation rate was only 20.0%, approximately the same as in cases with the CEA level<5 ng/mL. Conclusions: There is a positive correlation between serum CEA expression level and EGFR mutation status in NSCLC patients, namely the EGFR mutation-positive rate increases as the serum CEA expression level rises within a certain range (${\geq}20ng/mL$, especially 20~49 ng/mL). If patient samples are not suitable for EGFR mutation testing, or cannot be obtained at all, testing serum CEA levels might be a simple and easy screening method. Hence, for the NSCLC patients with high serum CEA level (${\geq}20ng/mL$, especially 20~49 ng/mL), it is worthy of attempting EGFR-TKI treatment, which may achieve better clinical efficacy and quality of life.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.13 no.8
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• pp.675-680
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• 2000

In this study the temperature coefficient of resonant frequency(TC $F_{r}$) dielectric and piezoelectric properties of Pb[(S $b_{1}$2//N $b_{1}$2/)$_{0.065}$)-(Z $r_{x}$, $Ti_{1-x}$ )$_{0.90}$] $O_3$ceramics were investigated with Zr/Ti ratio. The compositions near the morphotropic phase boundary (MPB) appeared when Zr/Ti ratio was 49.5/50.5 The dielectric constant and electromechanical coupling factor( $k_{p}$) also showed the highest values of 1,257, 0.653 respectively when the Zr/Ti ratio was 49.5/50.5 Moreover the mechanical quality factor( $Q_{m}$) showed th lowest value of 713 when the Zr/Ti ratio. The temperature coefficient of resonant frequency(TC $F_{r}$) abruptly change at the morphotropic phase boundary(MPB) which existed between the rhombohedral phase with highly negative TC $F_{r}$ of -106ppm/$^{\circ}C$ and the tetragonal phase with highly positive TC $F_{r}$ of +64pp $m^{\circ}C$ as Zr/Ti ratio varied from 50/50 to 49.5/50.5.50.5..50.5.

• Journal of Animal Science and Technology
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• v.49 no.5
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• pp.593-598
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• 2007

The current study was undertaken to determine the effects of sex steroid hormones(estrogen, testosterone and 19-nortestosterone) on differentiation and proliferation of pig preadipocytes. The preadipocytes were isolated from the backfat of new-born female pigs by collagenase digestion. 10－8M and 10－7M sex steroid hormones were treated to the cultured preadipocytes. Sex steroid hormones treated during the early stage of cell growth did not affect differentiation and proliferation of preadipocytes. However, testosterone and 19- nortestosterone treated during the late stage of cell growth stimulated differentiation of pig preadipocytes.