• Title/Summary/Keyword: M49

Search Result 4,691, Processing Time 0.046 seconds

Simulated Moving Bed(SMB) Chromatography Simulation for Loxoprofen Racemates Separation (록소프로펜 라세미체 분리를 위한 유사이동층 크로마토그래피의 전산모사)

  • Kim, In Ho;Song, Sung Moon
    • Korean Chemical Engineering Research
    • /
    • v.49 no.5
    • /
    • pp.623-627
    • /
    • 2011
  • Simulated moving bed(SMB) chromatography was simulated for separating loxoprofen racemates. Aspen chromatography simulator was utilized with Henry's constants of loxoprofen racemates which were obtained by batch chromatography experiments. Raffinate stream concentrations as well as purities were calculated with various $m_2$ and $m_3$ values in the triangle diagram obtained from two Henry's constants 7.9 and 10.1. Purity values are high under the conditions that the $m_2-m^3$ coordinates are near the left central region in the diagram and feed flow rates are lower. Concentration profiles of raffinate and extract streams along SMB columns explain the purity change in the case of increasing the column numbers installed at SMB.

Development of decontamination equipment to remove hot particulates contaminated in hot cell at KAERI

  • Kim Gye-Nam;Narayan M.;Won Hui-Jun;Jung Chong-Hun;Oh Won-Zin;Park Jin-Ho
    • Proceedings of the Korean Radioactive Waste Society Conference
    • /
    • 2005.11b
    • /
    • pp.258-268
    • /
    • 2005
  • A new approach has been adopted to remove the hot particulates from nuclear facilities, KAERI, South Korea, by using the new compact cyclone train, made of steel ness steel, with optional vortex finder length. Flow rate results showed a dramatic change in removal efficiency, performance was changed with the change of exit tube length. The 15 m/s flow rate was found suitable one for new equipment with the 49 mm optimum exit tube length for 76 mm cyclone body diameter. Results shows the removal efficiency for $1\;{\mu}m$ was more than $65\%$ and for $10\;{\mu}m$ was seen ${\~}97\%$. Over 15 m/s flow rate, was not shown much different in removal efficiency. The removal efficiency increased with the flow rate, and pressure drop. Cut size diameter decrease with the inlet flow rate. Cut size diameter found lowest with 49 mm exit tube length and 15 m/s flow rate. For filters the performance decreased with the inlet velocity increased.

  • PDF

Protein kinase C와 이와 관련된 단백질 연구

  • 이재란;김진한;최명언
    • Proceedings of the Korean Society of Applied Pharmacology
    • /
    • 1993.04a
    • /
    • pp.135-135
    • /
    • 1993
  • 신호전달과정에 중요한 역할을 하고 있는 다기능 serinei/threonine 단백질인산화효소인 protein kinase C(PKC)의 연구를 위해 이 효소의 정제를 뇌에서 착수하였다 PKC의 활성측정을 myelin basic protein을 기질로 하여 20 mM Tris 완충용액 PH 7.5, 0.15 mM [${\gamma}$-$^{32}$P]ATP(3 $\times$ $10^{5}$ cpm), 0.1 mM $Ca^{2+}$, 10$\mu\textrm{g}$ phosphatidylserine과 2$\mu\textrm{g}$ diolein을 넣어 반응시켰다. 반응은 TCA로 정지시킨 후 방사성 단백질을 Millipore filter paper로 걸러 섬광 계수기로 읽었다. Cytosol PKC의 정제과정은 첫 단계에서 DEAE-cellulose를 사용하였으며, phenyl sepharose CL-4B와 protamine agarose를 연속적으로 이용하여 800배의 정제에 성공했다. SDS-PACE 상에서 80 kD로 나타났으며 순도는 95 % 이상이였다. 이를 이용 PKC의 각종 기질 연구에 착수하기 시작했으며, 이중 MBP의 인산화연구를 통한 myelin의 안정성과 MBP와의 구조 관계가 일부 수행되고 있다 연차적으로 PKC와 이와 관련된 단백질의 특성을 살피기 위해 뇌의 PKC 기질 중 cold stress를 통해 환경에 민감한 것을 찾고 있으며, 현재 autoradiography를 이용해 80 kD, 54 kD, 49 kD와 35 kD의 단백질이 연구대상이 되고있다. 그 중 49 kD는 B-50(또는 GAP43, neuromodulin이라고도 함)일 가능성이 높아 이 단백질 조절과 PKC 활성화 사이의 관계 정립이 흥미로운 과제로 대두되고 있다.다.

  • PDF

Optimal Medium Composition Suitable for Enhancement of Biofertilizer's Shelf Life

  • Lee, Yong-Seong;Park, Yun-Suk;Kim, Kil-Yong
    • Korean Journal of Soil Science and Fertilizer
    • /
    • v.49 no.5
    • /
    • pp.456-460
    • /
    • 2016
  • Biofertilizers are increasingly available in the market as one of the alternatives to chemical fertilizers. The supply of a high number of viable microorganisms is important for farmers. Lysobacter capsici YS1215 producing chitinases and gelatinases, isolated from soil in Korea, was evaluated for the establishment of an optimal medium condition of its shelf life under an in vitro condition. In this study, the population density of a biofertilizer (L. capsici YS1215) in media containing crab shell and gelatin powder (M1, M2, M3 and M4) was observed to be higher than that of populations grown in TSB (Tryptic soy broth) media (M5, M6 and M7) during experimental period. In addition, the population density at 11 months was over $10^6\;CFU\;mL^{-1}$ in M1, M3 and M4, but under $10^6\;CFU\;mL^{-1}$ in M2, M5, M6 and M7. The best optimal medium for the shelf life was M1 ($2.6{\times}10^6\;CFU\;mL^{-1}$) containing both chitinous and gelatinous materials at 11 months. Therefore, this study provided results of the appropriate medium composition for the enhancement of the shelf life of L. capsici YS1215.

Experimental and numerical investigation of composite conical shells' stability subjected to dynamic loading

  • Jalili, Sina;Zamani, Jamal;Shariyat, M.;Jalili, N.;Ajdari, M.A.B.;Jafari, M.
    • Structural Engineering and Mechanics
    • /
    • v.49 no.5
    • /
    • pp.555-568
    • /
    • 2014
  • In this article, stability of composite conical shells subjected to dynamic external pressure is investigated by numerical and experimental methods. In experimental tests, cross-ply glass woven fabrics were selected for manufacturing of specimens. Hand-layup method was employed for fabricating the glass-epoxy composite shells. A test-setup that includes pressure vessel and data acquisition system was designed. Also, numerical analyses are performed. In these analyses, effect of actual geometrical imperfections of experimental specimens on the numerical results is investigated. For introducing the imperfections to the numerical models, linear eigen-value buckling analyses were employed. The buckling modes are multiplied by very small numbers that are derived from measurement of actual specimens. Finally, results are compared together while a good agreement between results of imperfect numerical analyses and experimental tests is observed.

RE-ACCELERATION MODEL FOR THE 'TOOTHBRUSH' RADIO RELIC

  • KANG, HYESUNG
    • Journal of The Korean Astronomical Society
    • /
    • v.49 no.3
    • /
    • pp.83-92
    • /
    • 2016
  • The Toothbrush radio relic associated with the merging cluster 1RXS J060303.3 is presumed to be produced by relativistic electrons accelerated at merger-driven shocks. Since the shock Mach number inferred from the observed radio spectral index, Mradio ≈ 2.8, is larger than that estimated from X-ray observations, MX ≲ 1.5, we consider the re-acceleration model in which a weak shock of Ms ≈ 1.2 - 1.5 sweeps through the intracluster plasma with a preshock population of relativistic electrons. We find the models with a power-law momentum spectrum with the slope, s ≈ 4.6, and the cutoff Lorentz factor, γe,c ≈ 7-8×104 can reproduce reasonably well the observed profiles of radio uxes and integrated radio spectrum of the head portion of the Toothbrush relic. This study confirms the strong connection between the ubiquitous presence of fossil relativistic plasma originated from AGNs and the shock-acceleration model of radio relics in the intracluster medium.

REAL HYPERSURFACES OF TYPE A IN COMPLEX TWO-PLANE GRASSMANNIANS RELATED TO THE NORMAL JACOBI OPERATOR

  • Jeong, Im-Soon;Suh, Young-Jin;Tripathi, Mukut Mani
    • Bulletin of the Korean Mathematical Society
    • /
    • v.49 no.2
    • /
    • pp.423-434
    • /
    • 2012
  • In this paper we give a characterization of real hypersurfaces of type (A) in a complex two-plane Grassmannian $G_2(\mathbb{C}^{m+2})$ which is a tube over a totally geodesic $G_2(\mathbb{C}^{m+1})$ in $G_2(\mathbb{C}^{m+2})$, in terms of two commuting conditions related to the normal Jacobi operator and the shape operator.

AN INJECTIVITY THEOREM FOR CASSON-GORDON TYPE REPRESENTATIONS RELATING TO THE CONCORDANCE OF KNOTS AND LINKS

  • Friedl, Stefan;Powell, Mark
    • Bulletin of the Korean Mathematical Society
    • /
    • v.49 no.2
    • /
    • pp.395-409
    • /
    • 2012
  • In the study of homology cobordisms, knot concordance and link concordance, the following technical problem arises frequently: let ${\pi}$ be a group and let M ${\rightarrow}$ N be a homomorphism between projective $\mathbb{Z}[{\pi}]$-modules such that $\mathbb{Z}_p\;{\otimes}_{\mathbb{Z}[{\pi}]}M{\rightarrow}\mathbb{Z}_p{\otimes}_{\mathbb{Z}[{\pi}]}\;N$ is injective; for which other right $\mathbb{Z}[{\pi}]$-modules V is the induced map $V{\otimes}_{\mathbb{Z}[{\pi}]}\;M{\rightarrow}\;V{\otimes}_{\mathbb{Z}[{\pi}]}\;N$ also injective? Our main theorem gives a new criterion which combines and generalizes many previous results.

FINITENESS PROPERTIES GENERALIZED LOCAL COHOMOLOGY WITH RESPECT TO AN IDEAL CONTAINING THE IRRELEVANT IDEAL

  • Dehghani-Zadeh, Fatemeh
    • Journal of the Korean Mathematical Society
    • /
    • v.49 no.6
    • /
    • pp.1215-1227
    • /
    • 2012
  • The membership of the generalized local cohomology modules $H_a^i$(M,N) of two R-modules M and N with respect to an ideal a in certain Serre subcategories of the category of modules is studied from below ($i<t$). Furthermore, the behaviour of the $n$th graded component $H_a^i(M,N)_n$ of the generalized local cohomology modules with respect to an ideal containing the irrelevant ideal as $n{\rightarrow}-{\infty}$ is investigated by using the above result, in certain graded situations.

SOLVABILITY OF GENERAL BACKWARD STOCHASTIC VOLTERRA INTEGRAL EQUATIONS

  • Shi, Yufeng;Wang, Tianxiao
    • Journal of the Korean Mathematical Society
    • /
    • v.49 no.6
    • /
    • pp.1301-1321
    • /
    • 2012
  • In this paper we study the unique solvability of backward stochastic Volterra integral equations (BSVIEs in short), in terms of both the adapted M-solutions introduced in [19] and the adapted solutions via a new method. A general existence and uniqueness of adapted M-solutions is proved under non-Lipschitz conditions by virtue of a briefer argument than the ones in [13] and [19], which modifies and extends the results in [13] and [19] respectively. For the adapted solutions, the unique solvability of BSVIEs under more general stochastic non-Lipschitz conditions is shown, which improves and generalizes the results in [7], [14] and [15].