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Changes in Plasma Levels of Thyroid and Sex Steroid Hormones in Rockfish (Sebastes schlegeli) during Maturation and Parturition Periods (조피볼락(Sebastes schlegeli)의 성숙$\cdot$출산기에 있어서 갑상선 및 성 스테로이드 호르몬의 혈중 변화)

  • KANG Duk Yong;CHANG Young Jin;SOHN Young Chang;AIDA Katsumi
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.31 no.4
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    • pp.574-580
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    • 1998
  • Changes in plasma levels of thyroid and sex steroid Hormones were examined during maturation and parturition periods in rockfish (Sebastes schlegeli) cultured in net pens. Plasma L-thyroxine levels were $35.2{\pm}5.7\;ng/m{\ell}\;(n=\;5;\;mean\;{\pm}\;sem)$ at vitellogenesis stage and then significantly decreased to $20.5\;{\pm}\;4.2\;ng/m{\ell}$ at parturition stage (P<0.05), and rapidly returned to high level, $44.9{\pm}\;7.2\;ng/m{\ell}$ at resting stage. Plasma 3,5,3'-triiodo-L-thyronine levels were 12.9 $\pm$ 1.6 ng/ml at vitellogenesis stage, but significantly decreased to $3.7{\pm}0.7\;ng/m{\ell}$ at ovulation stage (P<0.05) and increased to $52.9{\pm}7.0\;ng/m{\ell}$ at jesting stage. Plasma estradiol-17 $\beta$ level showed the highest value ($4.3{\pm}0.9\;ng/m{\ell}$) at vitellogenesis stage, but the level significantly decreased to $0.3{\pm}0.1\;ng/m{\ell}$, during parturition stage (P<0.05). In vitellogenesis and ovulation stages, plasma testosterone levels were $1.8{\pm}0.3\;ng/m{\ell}$ and $2.1{\pm}0.7\;ng/m{\ell}$, respectively, thereafter the level significantly decreased to $0.1{\pm}0.1\;ng/m{\ell}$ at parturition stage (P<0.05). These findings suggest that thyroid hormones may have relation to maturation and parturition of mother rockfish.

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Measurement of Thermal Diffusivity and the Optical Properties of a Carbon Nanotube Dispersion by Using the Thermal Lens Effect (열렌즈 효과를 이용한 탄소 나노 튜브 분산액의 열확산도와 광학적 특성 측정)

  • Park, Hyunwoo;Kim, Hyunki;Kim, Sok Won;Lee, Joohyun
    • New Physics: Sae Mulli
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    • v.68 no.11
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    • pp.1167-1172
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    • 2018
  • Carbon nanotubes (CNTs) are structures of carbon atoms bonded together in hexagonal honeycomb shapes, with multi-walled CNTs having a very high thermal conductivity of $3000W/m{\cdot}K$ and single-walled CNTs having a conductivity of $6000W/m{\cdot}K$. In this work, the transmittance and the thermal diffusivity of a multi-walled carbon nanotube dispersion with a concentration of 1.5 M were measured using a single beam method, a dual beam method, and the thermal lens effect. The nonlinear optical coefficients were obtained by using the z-scan method, which moved the sample in the direction of propagation of the single laser beam, propagation and the thermal diffusivity was measured using a double laser beam. As a pump beam, a diode-pumped solid state (DPSS) laser with a wavelength of 532 nm and an intensity of 100 mW was used. As the probe beam, a He-Ne laser having a wavelength of 633 nm and an intensity of 5 mW was used. The experimental result shows that when the concentrations of the sample were 9.99, 11.10, 16.65, and 19.98 mM, the nonlinear absorption coefficients were 0.046, 0.051, 0.136 and 0.169 m/W, respectively. Also, the nonlinear refractive indices were 0.20, 0.51, 1.25 and $1.32{\times}10^{-11}m^2/W$, respectively, and the average thermal diffusivity was $1.33{\times}10^{-6}m^2/s$.

Suspended Sediments Influx and Variation of Surface Sediments Composition in Semi-enclosed Bay -Spring Season in Yeoja Bay South Coast of Korea- (반폐쇄된 만내 부유퇴적물 유.출입과 표층퇴적물 조성 변화 -남해 여자만 봄철-)

  • Choi, Jeong-Min;Woo, Han-Jun;Lee, Yeon-Gyu
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.10 no.1
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    • pp.1-12
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    • 2007
  • Mooring survey for measurement of tidal current and suspended sediments was carried out at 4 inlets of Yeoja Bay in April, 2000 in order to understand the source of sediment supply. Net suspended sediment transport load during 2 tidal cycles through the M-1(West Inlet) was $133.88\;kg{\cdot}m^{-1}$ toward the Yeoja Bay, whereas the flux through the M-2(Jabal Inlet) was outward the Bay with the amount of $146.43\;kg{\cdot}m^{-1}$. The influx through the M-3 and 4(Bulgyo and Dong Isa Stream) was $23.25\;kg{\cdot}m^{-1}$ and $4,312.31\;kg{\cdot}m^{-1}$ toward the Yeoja Bay, respectively. Influx of suspended sediment on Yeoja Bay mainly occurred in the Dong Isa Stream. In the wet season the composition of surface was coarser-grained than dry season, possibly due to the influx of silty sediment from Dong Isa Stream In the wet season.

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Metal-Dinitrosyl Complexes(III) : Synthesis and Structural Study of Homo-, Hetero-dinuclear Molybdenum and Tungsten Complexes, $[Cl(phen)(NO)_2M({\mu}-pyz)M'(NO)_2(phen)Cl][ClO_4]_2 $(phen = 1,10-phenanthroline, pyz = pyrazine) (금속-디니트로실 착물 (제 3 보) : 몰리브덴과 텅스텐의 호모 및 헤테로 이핵 착물, $[Cl(phen)(NO)_2M({\mu}-pyz)M'(NO)_2(phen)Cl][ClO_4]_2 (phen=1,10-phenanthroline,\;pyz=pyrazine)$의 합성 및 구조에 대한 연구)

  • Sang-Oh Oh;Seong-Jong Mo
    • Journal of the Korean Chemical Society
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    • v.37 no.7
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    • pp.655-661
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    • 1993
  • The neutral monomeric compounds $[Mo(NO)_2Cl_2(phen)]$ and $[W(NO)_2Cl_2(phen)]$ (phen= 1,10-phenanthroline) have been prepared by reactions of polymeric compounds $[{Mo(NO)_2Cl_2}n],\;[{W(NO)_2Cl_2}n]$ with chelate ligands. Additions of one equivalent of silver(I) perchlorate to these cis-dinitrosyl compounds in acetone solution produce $[Mo(NO)_2(phen)(S)Cl][ClO_4]\;and\;[W(NO)_2(phen)(S)Cl][ClO_4]$ (S = acetone). The homo- and hetero-dinuclear complexes, $[Cl(phen)(NO)_2M(pyz)M'(NO)_2(phen)Cl][ClO_4]_2$ (M = Mo, W) and $[Cl(phen)(NO)_2M(pyz)M'(NO)_2(phen)Cl][C1O_4]_2$ (M = Mo, M' = W) have been prepared by these monocationic complexes with pyrazine ligand respectively. These complexes characterized by elemental analysis, $1^H-\;and\;^{13}C-NMR$, infrared, and UV-visible spectroscopy are reported. The spectral data indicate that homo- and hetero-dinuclear complexes were symmetrical structures of $C_{2v}$.

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A Research of the Width of Passage in the Elementary School Classroom - Centered on Elementary Schools in Northen Gyeonggi Province - (초등학교 일반교실의 통로폭에 관한 조사 연구 - 경기 북부지역 초등학교를 중심으로 -)

  • Yoon, Hee-Cheol
    • The Journal of Sustainable Design and Educational Environment Research
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    • v.17 no.3
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    • pp.26-34
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    • 2018
  • This research is a pre-research to find out profit module of 20 students in a classroom. I researched the widths of passages in the 30 classrooms of 5 elementary schools in Nothern Kyeonggi-do. I found the conclusions as follows. 1st, the area of 1 student's unit is $650(W){\times}950(D)$ 2nd, most of classrooms' students table placements are one-way types(77%). U-types are 13%. group study-types are 7% 3rd, The width between blackboard and front student's table is 2.08m. The width of passage between back seat and backboard is 1.12m. The width of passage between side wall and near student's table is 0.89m. The width of passage between window and near student's table is 0.74m. The width of vertical passage(A) between student's tables is 0.68m. The width of vertical passage(B) between student's tables is 0.7m. 4th, The area of teachers' is $2.1m{\sim}2.25m{\times}2.1m=4.41{\sim}4.73m^2$

Consolidation Behavior of Soft Ground by Prefabricated Vertical Drains (페이퍼드레인 공법에 의한 연약지반의 압밀거동)

  • Lee, Dal Won;Kang, Yea Mook;Kim, Seong Wan;Chee, In Taeg
    • Korean Journal of Agricultural Science
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    • v.24 no.2
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    • pp.145-155
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    • 1997
  • The large scaled field test by prefabricated vertical drains was performed to evaluate the superiority of vertical discharge capacity for drain materials through compare and analyze the time-settlement behavior with drain spacing and the compression index and consolidation coefficient obtained by laboratory experiments and field monitoring system. 1. The relation of measurement settlement($S_m$) versus design settlement($S_t$) and measurement consolidation ratio($U_m$) versus design consolidation ratio($U_t$) were shown $S_m=(1.0{\sim}1.1)S_t$, $U_m=(1.13{\sim}1.17)U_t$ at 1.0m drain spacing and $S_m=(0.7{\sim}0.8)S_t$, $U_m=(0.92{\sim}0.99)U_t$ at l.5m drain spacing, respectively. 2. The relation of field compressing index($C_{cfield}$) and virgin compression index($V_{cclab.}$) was shown $C_{cfield}=(1.0{\sim}1.2)V_{cclab.}$, But it was nearly same value when considered the error with determination method of virgin compression index and prediction method of total settlement. 3. Field consolidation coefficient was larger than laboratory consolidation coefficient, and the consolidation coefficient ratio($C_h/C_v$) were $C_h=(2.4{\sim}3.0)C_v$. $C_h=(3.5{\sim}4.3)C_v$ at 1.0m and 1.5m drain spacing and increased with increasing of drain spacing. 4. The evaluation of vertical discharge capacity with drain spacing from the results of the consolidation coefficient ratio showed largely superior in case the Mebra drain and Amer drain than other drain materials at 1.0m and 1.5m drain spacing, while the values showed nearly same value in case same drain spacing.

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Antioxidative Activity of Extracts from Sambucus williamsii var. coreana (딱총나무(Sambucus williamsii var. coreana) 추출물의 항산화효과)

  • Chae, Jung-Woo;Cho, Young-Je
    • Korean Journal of Plant Resources
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    • v.25 no.4
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    • pp.363-371
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    • 2012
  • Sambucus williamsii var. coreana have been used as a traditional medical food. This research was conducted to investigate the antioxidants of S. williamsii var. coreana leave and stem extracts. Total phenolic content of S. williamsii var. coreana leaves and stem water extracts were 6.6 and 2.0 mg/mL. The EDA by DPPH free radical scavenging test of S. williamsii var. coreana leaves extracts were 99.5 and 89.7% in water and ethanol extracts contained phenolic 200 ${\mu}g/mL$. The stem extracts were 92.2 and 94.3% in water and ethanol extracts contained phenolic 200 ${\mu}g/mL$. The ABTS radical decolorization activity of water and ethanol extracts from leaves were 79.8 and 99.1% at phenolic 200 ${\mu}g/mL$ and water and ethanol extracts from stem were 90.8 and 97.2% at phenolic 200 ${\mu}g/mL$. The antioxidant protection factor of water and ethanol extracts from leaves were 1.1 PF and 1.1 PF at phenolic 200 ${\mu}g/mL$ and water and ethanol extracts from stem were 1.4 PF and 1.0 PF at phenolic 200 ${\mu}g/mL$. The TBARs of water and ethanol extracts from leaves were 88.7 and 98.1% at phenolic 200 ${\mu}g/mL$ and water and ethanol extracts from stem were 93.6 and 90.6% at phenolic 200 ${\mu}g/mL$. The antioxidative activities of extracts from S. williamsii var. coreana leaves and stem were higher than BHT as positive control. These results suggests that S. williamsii var. coreana extracts have the greatest property as a natural antioxidative source.

Mislocalization of TORC1 to Lysosomes Caused by KIF11 Inhibition Leads to Aberrant TORC1 Activity

  • Jang, Yoon-Gu;Choi, Yujin;Jun, Kyoungho;Chung, Jongkyeong
    • Molecules and Cells
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    • v.43 no.8
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    • pp.705-717
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    • 2020
  • While the growth factors like insulin initiate a signaling cascade to induce conformational changes in the mechanistic target of rapamycin complex 1 (mTORC1), amino acids cause the complex to localize to the site of activation, the lysosome. The precise mechanism of how mTORC1 moves in and out of the lysosome is yet to be elucidated in detail. Here we report that microtubules and the motor protein KIF11 are required for the proper dissociation of mTORC1 from the lysosome upon amino acid scarcity. When microtubules are disrupted or KIF11 is knocked down, we observe that mTORC1 localizes to the lysosome even in the amino acid-starved situation where it should be dispersed in the cytosol, causing an elevated mTORC1 activity. Moreover, in the mechanistic perspective, we discover that mTORC1 interacts with KIF11 on the motor domain of KIF11, enabling the complex to move out of the lysosome along microtubules. Our results suggest not only a novel way of the regulation regarding amino acid availability for mTORC1, but also a new role of KIF11 and microtubules in mTOR signaling.

Helianthus tuberosus Extract Has Anti-Diabetes Effects in HIT-T15 Cells (HIT-T15 세포에서 돼지감자 추출물의 항당뇨 효과)

  • Kim, Jeong-Lan;Bae, Cho-Rong;Cha, Youn-Soo
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.39 no.1
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    • pp.31-35
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    • 2010
  • This study was designed to evaluate anti-diabetes effect of Helianthus tuberosus extract (HT) in HIT-T15 cells. There were 5 experimental groups according to treatment NC (0 ${\muL/mL$), HT2 (1.1 ${\muL/mL$), HT3 (1.5 ${\muL/mL$), IN2 (1.8 ${\muL/mL$), IN3 (2.5 ${\muL/mL$). Inulin (IN) was used as a positive control for the Helianthus tuberosus extract groups. Cell viability was significantly increased in the HT3 (1.5 ${\muL/mL$), IN2 (1.8 ${\muL/mL$), IN3 (2.5 ${\muL/mL$) groups, compared with the NC group. There was no significant difference in cytotoxicity among all groups. Cell survival by MTT assay with alloxan was significantly increased in the HT2 (1.1 ${\muL/mL$), HT3 (1.5 ${\muL/mL$) groups, compared with the NC group. Insulin secretion and NAD+/NADH ratio were significantly increased in the HT3 group, compared with the NC group. We found that Helianthus tuberosus extract increased cell viability, had a protective effect on $\beta$-cells, and increased insulin secretion level and $NAD^+$/NADH ratio in HIT-T15 cells. These results suggest that Helianthus tuberosus extract improves the diabetes-related factors.

Separation of Fission Products by Ion Exchange Method (이온 교환법(交換法)에 의한 핵분열생성물(核分裂生成物)의 분리(分離))

  • Lee, Byung-Hun;Bang, Je-Geon
    • Journal of Radiation Protection and Research
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    • v.8 no.1
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    • pp.15-25
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    • 1983
  • The sequential separation of Ru-103, Cs-137 and Ce-144 was carried out by organic cation exchanger, Amberite CG-120, and inorganic ion exchangers, silica gel and montmorillonite. The optimum conditions of Ru-103, Cs-137 and Ce-144 on Amberite CG-120 are 0.01M-, 0.01M- and 0.1IM- hydrochloric acid for the adsorption, and 3M-, 3M- and 5M-hydrochloric acid for the desorption, respectively. The optimum conditions of Ru-103, Cs-137 and Ce-144 on silica gel are pH 8, pH 8 and pH 8 for the adsorption. and 3M-, 1M- and 1M-hydrochloric acid for the desorption. respectively. The optimum conditions of Ru-103, Cs-137 and Ce-144 on montmorillonite are pH 8, 0.01M-hydrochloric acid and pH 4 for the adsorption, and 1M-, 5M- and 3M-hydrochloric acid for the desorption. respectively. The adsorption which occurs at lower ionic strength and the differences in desorption ionic strength are utilized for the separation of tracer mixture in continuous experiments. The individual separation of Ru-103, Cs-137 and Ce-144 can be carried out more efficiently with montmorillonite than with silica gel and Amberite CG-120.

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