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Effect of Dietary Supplement of Mayonnaise on Lipid Metabolism in Rats (마요네즈 첨가 식이가 흰쥐의 지질 대사에 미치는 영향)

  • 조영자
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.28 no.4
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    • pp.895-900
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    • 1999
  • We have examined the effects of mayonnaise on the lipid metabolism and calcium bioavailability of rats by using myonnaise. Sprague Dawley male rats(131$\pm$5g) were divided into four dietary groups[Control (Con, 10% soybean oil), Mayonnaise(M5), 10% Mayonnaise(M10)and 15% Mayonnaise(M15)] were fed ad libitum with experimental diets for four weeks. Final body weight exhibited a decrease in the M10 group, also final thymus organ weight showed a significant decreasing trend(p<0.05). The levels of serum, liver and adipose total lipid were significantly different among the four experimental groups(p<0.05). Serum calcium levels were significantly lower in the M15 group than in among the groups(p<0.05). On the other hand, the elevation of serum cholesterol levels were not clearly observed, but triglyceride levels were elevated the M5 and M15 group. The P/S ratio of adipose tissue were higher in the M10 group(2.35$\pm$0.35) than any other groups. Free EDTA in mayonnaise was 0.0307~0.0387%, moisture 12.46~16.49% and calcium 0.012~0.019%. But commercial mayonnaise contained free EDTA higher than the safe use (0.0075%). Safety problems of EDTA additives resulted from mass processed mayonnaise are arising. Though the evaluation of safety can not reach a conclusion with only one or two clinical case studies. It often simply jumps to conclusion. Therefore more wide ranged discussion and deepened study is required to search for the solution of safety problems.

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Investigation of Antimicrobial Activity and Stability of Orixa japonica Thunb. Leaf Extract (상산나무 잎 추출물의 항균활성 및 안정성 조사)

  • Choe, Su-Bin;Kang, Sung-Tae
    • Korean Journal of Food Science and Technology
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    • v.46 no.1
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    • pp.39-43
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    • 2014
  • The antimicrobial activity of Orixa japonica Thunb. leaf extract towards 13 microorganism strains was evaluated. Both methanol (MEex) and 70% ethanol extracts showed antimicrobial activity towards Streptococcus mutans, Bacillus cereus, Staphylococcus aureus, and Pseudomonas aeruginosa. MEex showed a higher antimicrobial activity than the 70% ethanol extract. In addition, the dichloromethane fraction (DCMfr) of the MEex also had an antimicrobial effect against the microorganisms examined. The minimum inhibitory concentrations (MICs) towards S. mutans, B. cereus, S. aureus, and P. aeruginosa were 49.22, 24.61, 49.22, and 49.22 mg/mL, respectively. In contrast, the MICs of the DCMfr tpwards S. mutans, B. cereus, S. aureus, and P. aeruginosa were 3.31, 0.21, 1.7, and 1.7 mg/mL, respectively. The MEex antimicrobial activity was not affected by a 3 h exposures to pH in the range of 3-11 or by temperatures were maintained between $80^{\circ}C-100^{\circ}C$ for 6 h. However, the MEex antimicrobial activity decreased at a heat treatment of $121^{\circ}C$ 1 h.

ON SOME MEASURE RELATED WITH POISSON INTEGRAL ON THE UNIT BALL

  • Yang, Gye Tak;Choi, Ki Seong
    • Journal of the Chungcheong Mathematical Society
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    • v.22 no.1
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    • pp.89-99
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    • 2009
  • Let $\mu$ be a finite positive Borel measure on the unit ball $B{\subset}\mathbb{C}^n$ and $\nu$ be the Euclidean volume measure such that ${\nu}(B)=1$. For the unit sphere $S=\{z:{\mid}z{\mid}=1\}$, $\sigma$ is the rotation-invariant measure on S such that ${\sigma}(S)=1$. Let $\mathcal{P}[f]$ be the invariant Poisson integral of f. We will show that there is a constant M > 0 such that $\int_B{\mid}{\mathcal{P}}[f](z){\mid}^{p}d{\mu}(z){\leq}M\;{\int}_B{\mid}{\mathcal{P}}[f](z)^pd{\nu}(z)$ for all $f{\in}L^p({\sigma})$ if and only if ${\parallel}{\mu}{\parallel_r}\;=\;sup_{z{\in}B}\;\frac{\mu(E(z,r))}{\nu(E(z,r))}\;<\;\infty$.

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MiR-99a Inhibits Cell Proliferation and Tumorigenesis through Targeting mTOR in Human Anaplastic Thyroid Cancer

  • Huang, Hou-Gang;Luo, Xi;Wu, Shuai;Jian, Bin
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.12
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    • pp.4937-4944
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    • 2015
  • MicroRNAs (miRNAs) are emerging as critical regulators in carcinogenesis and tumor progression. Recently, miR-99a has been reported as a tumor suppressor gene in various human cancers, but its functions in the context of anaplastic thyroid cancer (ATC) remain unknown. In this study, we reported that miR-99a was commonly downregulated in ATC tissue specimens and cell lines with important functional consequences. Overexpression of miR-99a not only dramatically reduced ATC cell viability by inducing cell apoptosis and accumulation of cells at G1 phase, but also inhibited tumorigenicity in vivo. We then screened and identified a novel miR-99a target, mammalian target of rapamycin (mTOR), and it was further confirmed by luciferase assay. Up-regulation of miR-99a would markedly reduce the expression of mTOR and its downstream phosphorylated proteins (p-4E-BP1 and p-S6K1). Similar to restoring miR-99a expression, mTOR down-regulation suppressed cell viability and increased cell apoptosis, whereas restoration of mTOR expression significantly reversed the miR-99a antitumor activity and the inhibition of mTOR/p-4E-BP1/p-S6K1 signal pathway profile. In clinical specimens and cell lines, mTOR was commonly overexpressed and its protein levels were statistically inversely correlated with miR-99a expression. Taken together, our results demonstrated for the first time that miR-99a functions as a tumor suppressor and plays an important role in inhibiting the tumorigenesis through targeting the mTOR/p-4E-BP1/p-S6K1 pathway in ATC cells. Given these, miR-99a may serve as a novel prognostic/diagnostic and therapeutic target for treating ATC.

Modeling of the T.C.M.S. using Power Line Carrier in Railway

  • Song, Y.S.;Lee, S.G.;Shin, S.K.;Han, S.H.
    • 제어로봇시스템학회:학술대회논문집
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    • 2003.10a
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    • pp.2147-2150
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    • 2003
  • Recently, many technologies of the P.L.C (Power Line Carrier) are introduced for an efficient communication. P.L.C communication sends information in the carrier signals by conduction over the power wire. An arc detector is proposed in this paper for the effective transmission. The Power Line Carrier has an advantage in low cost because it uses existent power line. It can be easily applied anywhere that a power line socket is available. But the P.L.C. is very noisy, because many electronic devices in generate electronic noise in modulated signals. This problem should be considered carefully in the design of the arc detector system using P.L.C in railway. The proposed system can be applied for monitoring the arc detector system and the arc locator system in railway. Hence the system will be able to exchange the arc information to be T.C.M.S. (Train Control Management System), bogies and even between a station and trains in railway and use to suspicion fire in train.

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Studies on the Host Plant, Bionomics, and Damage of Bamboo Leaf Rollers in Chonnam Province Area (대나무의 잎말이나방류(類)에 대한 기주(寄主), 생태(生態) 및 피해(被害)에 관한 연구(硏究))

  • Kim, Kyu-Chin;Lee, Tae-Sik
    • Korean journal of applied entomology
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    • v.25 no.2 s.67
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    • pp.85-92
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    • 1986
  • This study was conducted to investigate host plant, bionomics, and damage on Bamboo Leaf Rollers in Chonnam area. Species of the leaf rollers attacking the bamboo trees in Chonnam area were Microstega jessica (Butler) and Sinibotys evenoralis (Walker). Among these species, M. jessica (B.) and S. evenoralis (W.) were observed in Damyang but S. evenoralis (W.) alone was found in Naju and Hwasoon. Among the 4 host plant species observed, Phyllostachys nigra var. henonis S., and P. nigra M. were first recorded as host plants of M. jessica (B.), and P. nigra var. henonis (S.) as host plant of S. evenoralis (W.). The occurrence of the M. jessica (B). was once a year with the peak about late May, whereas the occurrence of S. evenoralis (W.) was 2 times a year and the peaks were early June and mid-July, respectively. The average periods of each stage of M. jessica (B.) were 8 days for egg, 293 days for larva, 16 days for pupa, and the longevity of the adult was 12 days for females and 9 days for males. The average periods of each stage of S. evenoralis (W.) were in 1st generation, 11 days for egg, 28 days for larva, 12 days for pupa, and the longevity of the adults was 18 days for females and 15 days for males; and 2nd generation was 7 days for egg, 261 days for larva, 20 days for pupa, and the longevity of the adults was 11 days for females and 10 days for males. The time of most adult emergence of M. jessica (B.) was from 6 p.m. to 4 a.m. and the peak was 8 p.m. to 10 p.m. M. jessica (B,) overwintered as 6th instals in Bamboo shoot sheath but S. evenoralis (W.) overwintered as $1st{\sim}2nd$ instals on the tree leaves of Bamboo. The percentage of damaged leaves with different heights of Bamboo trees were 67.1% at upper portion, 19.0% at middle portion, 14.0% at lower portion. The percentage of damaged loaves with different Bamboo species was 57.0% on P. nigra var. henonis S., 36.5% on P. bambusoides S. et Z., 14.5% on P. pubescens M.. It was showed highly significant negative correlation between percentage of damaged bamboo leaves an tree growth stages.($r=-0.739^{**}$)

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Prion Protein Genotypes in Pakistani Goats

  • Babar, M.E.;Nawaz, M.;Nasim, A.;Abdullah, M.;Imran, M.;Jabeen, R.;Chatha, S.A.;Haq, A.U.;Nawaz, A.;Mustafa, H.;Nadeem, A.
    • Asian-Australasian Journal of Animal Sciences
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    • v.21 no.7
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    • pp.936-940
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    • 2008
  • The PCR-amplified prion protein (PrP) gene was sequenced to determine the frequency of scrapie-associated as well as novel PrP genotypes in 72 healthy goats representing five breeds. A total of six genotypes were detected, resulting from the three reported 143 (H/R), 154 (R/H) and 240 (S/P) and the two novel 39 (S/R) and 185 (I/F) amino acid polymorphisms. Of the four silent mutations 42 (a$\rightarrow$g), 138 (c$\rightarrow$t), 231 (c$\rightarrow$a) and 237 (g$\rightarrow$c) detected in this study, 237 (g$\rightarrow$c) is novel. A genotype (SIP/RFP) harboring three amino acid polymorphisms 39 (S/R), 185 (I/F) and 240 (S/P) was found in few goats. Although both scrapie-associated genotypes with 143 (H/R) and 154 (R/H) polymorphisms and others with 39 (S/R), 185 (I/F) and 240 (S/P) polymorphisms were present in the studied Pakistani goats, their frequency was lower than that of the wild-type genotype SHRIS/SHRIS (34.7%). These results emphasize the need for further sequencing of the PrP gene in a large number of goats representing the five studied breeds, so that overall PrP variability can be assessed in these breeds in research addressing future concerns about scrapie.

Study on the Polarographic Behaviors of Tl(I) in EDTA and NTA as Supporting Electrolytes (EDTA 및 NTA 支指電解質중 Thallium (I) 의 Polarography 에 關한 硏究)

  • Kim, Hwang-Am;Kim, Yong-Tai
    • Journal of the Korean Chemical Society
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    • v.6 no.1
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    • pp.61-63
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    • 1962
  • The polarographic behaviors of Tl(I) was investigated in EDTA and NTA as supporting electrolytes for determination of Tl(I). A base solution containing 0.005 % gelatine, 0.1 M EDTA, and 0.05 M NTA was used. The halfwave potential of Tl(I) determined is -0.495 V v.s. S.C.E. in 0.1 M EDTA at pH 4.1 and -0.520V v.s. S.C.E. in 0.05 M NTA at pH 6.3. In this paper, the effects of gelatine concentration and pH values was investigated. The half-wave potentials of common elements was determined and compared with the half-wave potential of Tl(I).

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M2M Standard Model and Advanced Machine Concept for u-Manufacturing (u-Manufacturing을 위한 M2M 표준화 및 진보된 Machine Concept)

  • Kim D.H.;Song J.Y.;Cha S.K.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2006.05a
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    • pp.345-346
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    • 2006
  • In the future, a machine will be more improved in the form of advanced concept with collaborative ability in M2M(Machine to Machine, Mobile to Machine) environment for u-Manufacturing system. This paper tried to standardize M2M and design advanced concept machine. The M2M is front-end system for implementing autonomous ubiquitous environment. The advanced machine in M2M will be a collaborative machine with knowledge-evolutionary ability such as u-Machine(Ubiquitous machine), Vortal(Vertical Portal) machine and P2P(Peer to Peer) machine. Such advanced concept machines will be the key subject for M2M cooperation.

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