• Title/Summary/Keyword: M-H curve

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Improvement in metabolic parameters in obese subjects after 16 weeks on a Brazilian-staple calorie-restricted diet

  • da Costa, Teresa H.M.;Reis, Caio E.G.;da Silva, Fabio V.P.;Casulari, Luiz A.
    • Nutrition Research and Practice
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    • v.8 no.4
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    • pp.410-416
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    • 2014
  • BACKGROUND/OBJECTIVES: The standard pattern of Brazilian food consumption is based on the combination of rice and beans served together in the main meals. This study assessed the effects of Brazilian-staple calorie-restricted (BS-diet) dietary advice, with brown rice and beans, on metabolic parameters, body composition, and food intake in overweight/obese subjects. SUBJECTS/METHODS: Twentyseven subjects were randomly assigned to a conventional-type calorie-restricted diet (CT-diet) (n = 13) or a BS-diet (n = 14). Glucose metabolism, lipid profile, anthropometric and body composition parameters, and food intake were measured before and after 16 weeks. Paired t-tests/Wilcoxon tests were used for comparison of differences from baseline and unpaired t-tests/Mann-Whitney tests were used for comparison of differences between the groups. RESULTS: After16 weeks, both groups showed reductions in weight and waist circumference (P < 0.02), and the BS-diet group showed a decrease in body fat (P = 0.0001), and significant improvement in glucose metabolism (fasting plasma glucose, glucose and insulin areas under the curve, Cederholm index, and HOMA2-$%{\beta}$) ($P{\leq}0.04$) and lipid profile (cholesterol, triacylglycerol, LDL-c, VLDL-c, and cholesterol/HDL-c ratio) ($P{\leq}0.05$). In addition, the BS-diet group showed significant improvement in HOMA2-$%{\beta}$, compared to the CT-diet group (P = 0.03). The BS-diet group also showed a significant reduction in energy, lipids, carbohydrate, and cholesterol intake ($P{\leq}0.04$) and an increase in fiber intake ($P{\leq}0.001$), while the CT-diet group showed a significant reduction in intake of energy, macronutrients, PUFA, and cholesterol ($P{\leq}0.002$). CONCLUSIONS: These results demonstrate the benefits of the BS-diet on metabolic parameters in obese subjects.

Role of cAMP, EGF, IGF-I and Protein Phosphorylation in Mammary Development I. Effect of EGF, IGF-I and Photoreactive Cyclic AMP on DNA Synthesis of Mammary Epithelial Cell (유선발달에 있어서 cAMP, EGF, IGF-I 및 단백질 인산화 작용의 역할 I. EGF, IGF-I 및 Photoreactive Cyclic AMP가 유선상피세포의 DNA합성에 미치는 효과)

  • 여인서;박춘근;홍병주
    • Korean Journal of Animal Reproduction
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    • v.17 no.1
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    • pp.49-56
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    • 1993
  • Mouse mammary epithelial cells(NMuMG) were plated onto 24 well phates(100,000 cells/well), in DMEM supplemented with 10% fetal calf serum. After serum starvation for 24 hours, EGF)0~100ng/ml) was added simultaneously with IGF-I(10ng/ml), 1$\mu$M photoreactive cAMP(4,5-dimethoxy-2-nitrobenzyl adenosine-3',5' cyclic monophosphate, DMNB) or IGF-I plus DMNB. After 2 hours, the cells were expposed to UV light(300nm, 3 second pulse0 in order to activate DMNB which induces a rapid transient increase in intracellular cAMP upon UV irradiation. DNA synthesis was estimated as incorporation of 3H-thymidine into DNA(1 hour pulse with 1$\mu$Ci/ml, 18~19 hours after UV exposure). Without IGF-I or DMNB, EGF(10 or 100ng/ml) increased DNA synthesis from 8,362 dpm/well in control to 16,345 or 18,684 dpm/well with EGF(pooled SE=1,239 dpm/well, P<0.05). IGF-I or IGF-I plus DMNB alone increased DNA synthesis from 8,362 dpm/well in control to 17,307 or 20,427 dpm/well, respectively(P<0.05). Addition of IGF-I, DMNB or IGF-I plus DMNB into 0~100ng/ml EGF did not significantly change the shape of dose response curve of EGF alone. In other experiment, EGF or IGF-I plus DMNB into 10ng/ml EGF group exhibited interaction effect in DNAsynthesis [EGF(10ng/ml)=18,497; IGF-I+EGF=22,837; DMNB+EGF=20,658 ; IGF-I+DMNB+EGF=29,658, pooled SE=1,055, P<0.05]. These results indicate that simultaneous activation of EGF, IGF-I and intracellular cAMP interact in DNA synthesis of mouse mammary epithelial cells.

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An implementation of NDIR type $CO_2$ gas sample chamber and measuring hardware for capnograph system in consideration of the time response characteristics (시간응답특성을 고려한 2광원 1센서 방식의 capnograph 시스템용 NDIR식 $CO_2$ 가스 챔버 설계 및 측정 회로의 구현)

  • Park, I.Y.;Lee, I.K.;Lee, S.K.;Kang, K.M.;Kang, S.W.;Cho, J.H.
    • Journal of Sensor Science and Technology
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    • v.10 no.5
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    • pp.279-285
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    • 2001
  • The capnograph system for determining the partial pressure of carbon dioxide in the blood of a patient was developed based on the NDIR(non-dispersive infrared) absorption technology. NDIR gas analyzing method requires an optical absorption chamber and signal processing hardware. In this paper, we have designed and implemented NDIR type $CO_2$ gas chamber in consideration of the time response characteristics and lamp chopping frequency. And we have implemented signal processing hardware using two infrared sources to reduce the thermal background effect. The implemented gas chamber and signal processing hardware were tested in the temperature variation experiment and human expiratory experiment. The results showed that the system could produce a stable output signal and a good $CO_2$ gas concentration curve like a typical capnogram.

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Effects of the Addition of Mn and $AB_5$ Type Alloy on the Electrochemical Characteristics of Ti-Cr-V BCC Type Alloys (BCC계 Ti-Cr-V 합금의 전기화학적 특성에 미치는 Mn 및 $AB_5$계 합금 첨가 효과)

  • Kim, J.Y.;You, J.H.;Park, C.N.;Park, C.J.;Choi, J.;Cho, S.W.
    • Journal of Hydrogen and New Energy
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    • v.18 no.1
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    • pp.52-59
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    • 2007
  • We investigated the effects of the addition of Mn and $AB_5$ type alloy on the electrochemical characteristics of Ti-Cr-V BCC type alloys as anode materials for Ni-MH battery. The activation behavior and discharge capacity of the BCC type alloys were significantly improved by ball-milling with the $LmNi_{4.1}Al_{0.25}Mn_{0.3}Co_{0.65}$ alloy, because the $AB_5$ type alloy acted as hydrogen path on the surface of the BCC type alloy. Among the Mn substituted alloys($Mn=0.03%{\sim}0.08%$), the $Ti_{0.32}Cr_{0.38}Mn_{0.05}V_{0.25}$ alloy ball-milled with $AB_5$ type alloy exhibited the greatest discharge capacity of $336\;mAh{\cdot}g^{-1}$. In addition, Mn substituted alloys exhibited the lower plateau pressure in P-C- T curve, the better hydrogen storage capacity and faster surface activation compared with the alloy without Mn.

Square Wave Voltammetry in Cathode Ray Tube Glass Melt Containing Different Polyvalent Ions (서로 다른 다가이온을 함유한 음극선관 전면유리 용융체의 Square Wave Voltammetry)

  • Kim, Ki-Dong;Kim, Hyo-Kwang;Kim, Young-Ho
    • Journal of the Korean Ceramic Society
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    • v.44 no.6 s.301
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    • pp.297-302
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    • 2007
  • With aids of square wave voltammetry (SWV) the redox behavior for various combination of polyvalent ions (Sb+Fe, Sb+Zn, Sb+Ce+Ti+Zn) was investigated in alkali-alkaline earth-silica CRT (Cathode Ray Tube) glass melts. The current-potential curve so called voltammogram was produced at temperature range of 1400 to $1000^{\circ}C$ under the scanned potential between 0 and -800 mV at 100 Hz. In the case of the Sb+Fe and Sb+Zn doped melts, peak for $Sb^{3+}/Sb^0$ shown voltammogram was shifted to negative direction comparing to the only Sb doped melts. However, according to voltammogram of Sb+Ce+Ti+Zn doped melt, Ti and Ce except Zn had hardly any influence on the redox reaction of Sb. Based on the temperature dependence of the peak potential, standard enthalpy (${\Delta}H^0$) and standard entropy (${\Delta}S^0$) for the reduction of $Fe^{3+}$ to $Fe^{2+}$, $Sb^{3+}$ to $Sb^0$, $Zn^{2+}$ to $Zn^0$ and $Ti^{2+}$ to $Ti^0$ in each polyvalent ion combination of CRT glass melts were calculated.

Differential Absorption Analysis of Nonmagnetic Material in the Phantom using Dual CT

  • Kim, Ki-Youl;Lee, Hae-Kag;Cho, Jae-Hwan
    • Journal of Magnetics
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    • v.21 no.2
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    • pp.286-292
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    • 2016
  • This study evaluates the change of computer tomography (CT) number in the case of the metal artifact reduction (MAR) algorithm, using the phantom. The images were obtained from dual CT using a gammex 467 tissue characterization phantom, which is similar to human tissues. The test method was performed by dividing pre and post MAR algorithm and measured CT values of nonmagnetic materials within the phantom. In addition, the changes of CT values for each material were compared and analyzed after measuring CT values up to 140 keV, using the spectral HU curve followed by CT scan. As a result, in the cases of N rod (trabecular bone) and E rod (trabecular bone), the CT numbers decreased as keV increasing but were constant above 90 keV. In the cases of I rod (dense bone) and K rod (dense bone), the CT numbers also decreased as keV increased but were uniform above 90 keV. The CT numbers from 40 keV to 140 keV were consistent in the cases of J rod (liver), D rod (liver), L rod (muscle), and F rod (muscle). For A rod (adipose), G rod (adipose), B rod (breast) and O rod (breast), the CT numbers increased as keV increased but were constant after 90 keV. The CT numbers from 40 keV to 140 keV were consistent in the cases of C rod (lung (exhale)), P rod (lung (exhale)), M rod (lung (inhale)) and H rod (lung (exhale)). Conclusively, because dual CT exhibits no changes in image quality and is able to analyze nonmagnetic materials by measuring the CT values of various materials, it will be used in the future as a useful tool for the diagnosis of lesions.

Influences of Magnetization Reversal and Magnetic Interaction on Coercivity of Sr-Ferrite Particles with Different Sizes (크기가 다른 Sr-Ferrite 입자의 자화 역전과 자기 상호작용이 보자력에 미치는 영향)

  • Kim, Hyeon Soo;Jeong, Soon Young;Kim, Kyung Min;Kwon, Hae-Woong
    • Journal of the Korean Magnetics Society
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    • v.27 no.1
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    • pp.23-29
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    • 2017
  • In this study, the influences of magnetization reversal and magnetic interaction on the coercivity of Sr-ferrite particles with different sizes were investigated through various magnetic measurements. The shape of the initial magnetization curve and the magnetic field dependence of the coercive force indicate that the magnetization reversal changes from domain nucleation to wall pinning as the particle size decreases. On the other hand, the Henkel plot, interaction field factor and ${\Delta}M(H)$ obtained from the DCD and IRM curves show that the strength of the dipolar interaction is increased with increasing the particle size. Therefore, it can be concluded that coercivity is closely related to magnetic interaction as well as magnetization reversal mechanism.

Acoustic Masking Effect That Can Be Occurred by Speech Contrast Enhancement in Hearing Aids (보청기에서 음성 대비 강조에 의해 발생할 수 있는 마스킹 현상)

  • Jeon, Y.Y.;Yang, D.G.;Bang, D.H.;Kil, S.K.;Lee, S.M.
    • Journal of rehabilitation welfare engineering & assistive technology
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    • v.1 no.1
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    • pp.21-28
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    • 2007
  • In most of hearing aids, amplification algorithms are used to compensate hearing loss, noise and feedback reduction algorithms are used and to increase the perception of speeches contrast enhancement algorithms are used. However, acoustic masking effect is occurred between formants if contrast is enhanced excessively. To confirm the masking effect in speeches, the experiment are composed of 6 tests; test pure tone test, speech reception test, word recognition test, pure tone masking test, formant pure tone masking test and speech masking test, and for objective evaluation, LLR is introduced. As a result of normal hearing subjects and hearing impaired subjects, more making is occurred in hearing impaired subjects than normal hearing subjects when using pure tone, and in the speech masking test, speech reception is also lower in hearing impaired subjects than in normal hearing subjects. This means that acoustic masking effect rather than distortion influences speech perception. So it is required to check the characteristics of masking effect before wearing a hearing aid and to apply this characteristics to fitting curve.

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나노질화 처리를 통한 사출금형 특성 연구

  • Sin, Hong-Cheol;Lee, Gyeong-Hwang;Kim, Dae-Uk
    • Proceedings of the Korean Vacuum Society Conference
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    • 2010.02a
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    • pp.105-105
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    • 2010
  • 자동차 차체부품에 적용되는 플라스틱 소재는 강도와 내마모성, 내충격성의 충분한 물성확보가 필요하며, 이에 플라스틱 소재의 기계적 특성 향상을 위해 유리 섬유가 다량 함유된 복합소재적용이 증가하고 있다. 반면 플라스틱이 고강도화함에 따라 제품 성형을 위한 사출 금형을 손상시키는 사례가 빈번하게 발생하고, 소재의 유동성 저하에 따른 사출 불량이 증가하고 있어 고강성 플라스틱 복합소재에 대응하는 고경도, 고내마모 특성이 부여된 사출 금형의 개발이 시급한 실정이다. 특히 사출 금형에 사용되는 소재는 기존 소재에 비해 우수한 내마모성과 함께 고광택을 유지하는 것이 더욱 중요해졌으며, 이에 따라 유럽, 일본과 국내 연구진에 의해 다양한 연구가 진행되고 있다. 그 중에서도 일본에서 개발되어 국내에도 소개된 래디칼 질화는 기존 질화법에 표면의 화합물 층만을 제어하는 것으로 다소의 표면 광택 효과는 있으나, 플라스틱 사출에 그대로 적용하기에는 무리가 따르므로 그 용도가 극히 제한적이다. 본 연구에서 적용한 나노 질화기술은 0.1torr 이하의 고진공에서 고밀도의 플라즈마 에너지를 발생시키는 방법으로 화합물층이 없는 나노 크기의 질화층을 소재 표면에 형성시키는 기술로서, 처리 후에도 표면의 색상 및 광택의 변화가 없는 것을 특징으로 한다. 또한 표면 경도 및 피로 특성을 향상시킴으로써 금형의 내구 수명을 향상시킬 것으로 기대된다. 본 연구에서는 KP4 금형 소재를 사용하여 플라즈마 이온 질화 시험 조건에 따른 소재의 경도 및 내마모 특성을 파악하고, 미세 조직 분석 및 XRD 분석 등을 통해 내마모 특성 향상에 대한 기본 특성을 평가하였다. 또한 인장시험을 통해 인장강도, 항복강도 및 연신율을 파악하고, 이를 토대로 고주기 피로시험을 실시함으로써 S-N curve를 얻고, 이를 통해 피로 강도 및 피로 수명에 미치는 나노 질화 처리의 영향을 파악하고자 하였다. 플라즈마 이온 질화 시험은 질소와 수소 비율($N_2:H_2$), 진공도, Screen bias voltage, Bias voltage를 변화시켰으며, 챔버 온도는 $400^{\circ}C$로 고정하였으며, 처리시간도 3시간으로 고정하였다. 질소와 수소의 비율은 3:1일 때 최고의 내마모 특성을 보였으며, 진공도는 내마모 특성에 큰 영향을 미치지 않는 것으로 관찰되었다. KP4의 초기 경도값은 약 302 Hv인 반면 최적의 나노 질화처리를 거친 시편에서는 800Hv 이상의 Vickers 경도값을 보였다. SEM 미세조직 분석과 EPMA를 통한 성분 분석을 시행한 결과 표층으로부터 약 $1.5{\mu}m$의 나노질화층을 확인할 수 있었다.

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Development of the Cost-Benefit Analysis System for the Investment of Safety Facilities in Chemical Plant (화학공장의 안전 설비 투자를 위한 비용$\cdot$편익 분석 시스템 개발)

  • Ko J. W.;Seo J. M.;Kim D. H.
    • Journal of the Korean Institute of Gas
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    • v.7 no.4 s.21
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    • pp.61-66
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    • 2003
  • The objective of this study is to develop a Cost-Benefit analysis system which would help us to make optimal decision among safety investment alternatives, calculating and comparing costs and benefits for facilities in chemical plants. So, the accident frequency analysis module and the accident damage prediction module were developed for estimating quantitative risks in chemical facilities, and domestic societal risk criterion was presented after the comparative analysis of major industrial cases and societal risk criteria of advanced countries like the Netherlands, Australia, U.S.A., U.K., and Germany. Also, the Cost-Benefit Analysis System which compares the safety investment alternatives based on their deduced net present values was developed through the selection of proper cost and benefit items by field studies

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