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A Prospective Clinical Trial on the Mg Oxidized Clinical Implants (마그네슘 양극산화 임플란트의 성공률에 관한 전향적 임상연구)

  • Im, So-Min;Kim, Dae-Gon;Park, Chan-Jin;Cho, Lee-Ra;Um, Heung-Sik;Lee, Jae-Kwan
    • Journal of Dental Rehabilitation and Applied Science
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    • v.27 no.1
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    • pp.25-39
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    • 2011
  • In animal studies, Magnesium (Mg) - incorporated oxidized implants showed significant enhancement of the bone response. This prospective clinical trial was performed to investigate the success rate, implant stability and marginal bone loss of Mg oxidized clinical implant. The experimental protocol was approved by Institutional Review Board of the Gangneung-Wonju National University Dental Hospital. Fifty healthy patients had partial edentulism were included in this study. Mg oxidized clinical implants (Implant M, Shinhung, Korea) were installed and restored with conventional protocol. The patients were recalled at 1, 3, 6 months after functional loading. Implant stability quotient (ISQ) was measured and periapical radiographic images were obtained. Amount of marginal bone loss was calculated with calibrated images from periapical radiographs. Repeated measured analysis of variance and post hoc Tukey test were used to compare the mean ISQ and bone level. A total of 101 implants were analyzed. The mean ISQ values increased continuously with time lapse from 68.4 at fixture installation to 71.5 at 6 months after loading. Implant stability was correlated with gender, fixture diameter, bone quality and implant sites. The mean marginal bone loss during 6 months after loading was 0.26 mm. There was no failed implant and six-month success rate was 100%. Within the limitations of this study, the six-month success rate of Mg oxidized implant was satisfactory. The implant stability and marginal bone level were excellent. However, further longer clinical studies will be needed to confirm the success of Mg oxidized clinical implant.

Determination of Residue Levels of Ethyl Carbamate in Alcoholic Beverages by Gas Chromatography/Tandem Mass Spectrometry (GC/MS/MS) (가스크로마토그래피/질량분석기(GC/MS/MS)를 이용한 주류 중 에틸카바메이트 잔류량 조사)

  • Kim, Dong-Ho;Jang, Han-Sub;Choi, Gu-Il;Kim, Hyun-Jung;Kim, Ho-Jin;Kim, Hyo-Lin;Kim, Keun-Sung
    • Journal of Food Hygiene and Safety
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    • v.28 no.1
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    • pp.63-68
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    • 2013
  • Ethyl carbamate (EC) is a contaminant generated in the fermentation processes of various fermented foods. In this study, residue levels of EC in 95 alcoholic beverage samples were determined by using Gas Chromatography/Tandem Mass Spectrometry (GC/MS/MS). All the samples were purified by a liquid-liquid extraction (LLE) method using dichloromethane. The LLE method enables an improvement in time and cost to detection and specificity over the conventional extraction methods. The limits of detection and quantification (LOD and LOQ) to analyze EC were 1.3 and 4.0 ng/mL, respectively. The recovery rates of EC were ranged from 90.0 to 97.5% at the levels of 50, 100, and 500 ug/L. Among traditional grain-based alcoholic beverage samples (n = 34), the average residue levels of EC in takju, yakju, and cheongju were 0.63, 7.01, and 14.11 ug/L, respectively. Among fruit-based alcoholic beverage samples (n = 48), those of EC in japanese apricot spirits, bokbunjaju, grape wines, and other fruit wines were 79.18, 1.66, 2.64, and 2.39 ug/L, respectively. Among distilled or diluted alcoholic beverage samples (n = 13), those of EC in soju (distilled or diluted), general distillates, liquors, and brandies were 0, 3.30, 8.20, and 8.52 ug/L, respectively. Therefore, this study reports that the residue levels of EC in the alcoholic beverages, distributed in the current domestic markets, did not reach its maximum allowed levels of 30 and 400 ug/L established for grape and fruit wines in Canada, respectively.

Geology and Tectonics of the Mid-Central Region of South Korea (남한(南韓) 중부지역(中部地域)의 토질(土質)과 지구조(地構造))

  • Kim, Ok Joon
    • Economic and Environmental Geology
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    • v.2 no.4
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    • pp.73-90
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    • 1969
  • The area studied is a southwestern part of Okcheon geosynclinal zone which streches diagonally across the Korean peninsula in the mid-central parts of South Korea, and is bounded by Charyeong mountain chains in the north and by Sobaek mountain chains in the south. The general trend of the zone is of NE-SW direction known as Sinian direction. Okcheon system of pre-Cambrian age occupies southwestern portion of Okcheon geosynclinal zone, and Choseon and Pyeongan systems of Cambrian to Triassic age in northeastern portion of the zone. It was defined by the writer that the former was called "Okcheon Paleogeosynclinal zone" and the latter "Okcheon Neogeosynclinal zone," although T. Kobayashi named them "Metamorphosed Okcheon zone" and "Non-metamorphosed Okcheon zone" respectively and thought that sedimentary formations in both zones were same in origin and of Paleozonic age, and C.M. Son also described that Okchon system was of post-Choseon (Ordovician) and pre-Kyeongsang (Cretaceous) in age. According to the present study two zones are separated by great fault so that the geology in both zones is not only entirely different in origin and age, but also their geolosical structures are discontinuous. Stratigraphy and structure of Okcheon system are clearly established and defined by the writer and its age is definitely pre-Cambrian. It is clarified by present study that the meta-sediments in and at vicinity of Charyeong mountain chains are correlated to Weonnam series of pre-Cambrian age which occupies and continues from northeast to southwest in and at south of Sobaek mountain chains, and both metasediments constitute basement of Okcheon system. Pyeongan, Daedong and Kyeongsang systems were deposited in few narrow intermontain basins in Okcheon paleogeosynclinal zone after it was emerged at the end of Carboniferous period. Granites of Jurassic and Cretaceous ages and volcanics of Cretaceous age are cropped out in the zone. Jurassic granite is aligned generally with the trend of Okcheon geosynclinal zone, whereas Cretaceous granite lacks of trend in distribution. Many isoclinal folds and thrust faults caused by Taebo orogeny at the end of Jurassic period are also parallel with Sinian directieon and dip steeply to northwest. Charyeong, Noryeong, Sobaek, and Deogyu mountain chains are located in areas of anticlinorium, and Kyongsang system in narrow synclinal zones. Folds in Okcheon neogeosynclinal zone are generally of N 70-80W direction but deviate to Sinian direction at the western parts of the zone. This phenomena is interpreted by the fact that the folds were originated by Songrim disturbance at the end of Triassic period and later partly modified by Taebo orogeny. Thrust faults of Taebo orogeny coentinue from Okcheon paleogeosynclinal zone into neogeosynclinal zone, forming imbricated structure as previously described. Strike-slip faults perpendicular to Sinian direction and shear faults diagonally across it by 55 degrees also prevail in neogeosynclinal zone. It is concluded from viewpoints on geology and geological structure that l)Okchon geosyncline had changed its location and affected by numerous disturbances through geologic time, and 2)mountain chains in the area such as Charyeong, Noryeong, Sobaek, and Deogyu were originated as folded mountains. Differing from others, however, Sobaek range was probably formed at the time of Songrim disturbance and modified later by Taebo orogeny. It is cut by Danyang-Jeomchon fault at the vicinity of Joryeong near Munkyeong village and does not continue to southwest beyond the fault, whereas southwestern portion of erstwhile Sobaek range continues to Taebaek rangd northeastward from Deogyusan passing through Sangju, Yecheon, and Andong. From these evidences, the writer has newly defined the erstwhile Sobaek range in such a way that Sobaek range is restricted only to northeastern portion and Deogyu range is named for the southwestern portion of previous Bobaek range.

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A Study of Accommodative Response on Emmetropia (정시안의 조절반응량에 관한 연구)

  • Shim, Hyun-Seog;Shim, Moon-Sik;Joo, Seog-Hee
    • Journal of Korean Ophthalmic Optics Society
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    • v.11 no.3
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    • pp.187-192
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    • 2006
  • The purpose of this research was to measurement real accmmnodative response amount of emmetropia using both eyes open-view auto-refractometer. We classified 377(male 146, female 231)eyes showing good naked vision at least 1.0, with a spherical equivalent refraction of under ${\pm}0.50D$ and cylindercal refraction of under -0.75D, from 10 to 59(mean $25.8{\pm}12.4$) years into 5 groups with 10 year interval and analyzed change of the near astigmatism and accommodative response amount to distinction of age. Age comparison, total mean 1.47D, 10 years age group 1.63D, 20 years age group 1.57D, 30 years age group 1.71D, 40 years age group 0.97D, and 50 years age group 0.05D. It was no difference between 10 to 30 years age group, But it showed the decre8.se which is remarkable from above 40 years age group and it does not almost response from above 50 years age group. Sexual difference, the man appeared some highly in male(mean $26.4{\pm}12.3$ years) 1.56D m female(mean $26.4{\pm}12.3$) 1.43D. Near-astigmatism power change, mean +0.12D, 10 years age group +0.06D, 20 years age group +0.16D, 30 years age group +0.09D, 40 years age group +0.05D, and 50 years age group +0,06D. No significant difference of astigmatism powers among the an groups, but from all years age group the astigmatism power appeared more highly far-astigmatism than near-astigmatism. Near-astigmatism axis change in the far-astigmatism changes at under ${\pm}10^{\circ}$ 103 eyes, above ${\pm}10^{\circ}$ rotation clockwise direction 108 eyes, above ${\pm}10^{\circ}$ rotation counter-clockwise direction 101 eyes. It was analyzed near-astigmatism axis change.

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Study on the production of porous CuO/MnO2 using the mix proportioning method and their properties (반응몰비에 따른 다공성 CuO/MnO2의 제조 및 특성 연구)

  • Kim, W.G.;Woo, D.S.;Cho, N.J.;Kim, Y.O.;Lee, H.S.
    • Analytical Science and Technology
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    • v.28 no.3
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    • pp.182-186
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    • 2015
  • In this study, the porous CuO/MnO2 catalyst was prepared through the co-precipitation process from an aqueous solution of potassium permanganate (KMnO4), manganese(II) acetate (Mn(CH3COO)2·4H2O) and copper(II) acetate (Cu(CH3COO)2·H2O). The phase change in MnO2 was analyzed according to the reaction molar ratio of KMnO4 to Mn(CH3COO)2. The reaction mole ratio of KMnO4 to Mn(CH3COO)2·4H2O was varied at 0.3:1, 0.6:1, and 1:1. The aqueous solution of Cu(CH3COO)2 was injected into a mixed solution of KMnO4 and Mn(CH3COO)2 to 10~75 wt% relative to MnO2. The Cu ion co-precipitates as CuO with MnO2 in a highly dispersed state on MnO2. The physicochemical property of the prepared CuO/MnO2 was analyzed by using the TGA, DSC, XRD, SEM, and BET. The different phase types of MnO2 were prepared according to the reaction mole ratio of KMnO4 to Mn(CH3COO)2·4H2O. The results confirmed that the porous CuO/MnO2 catalyst with γ-phase MnO2 was produced in the reaction mole ratio of KMnO4 to Mn(CH3COO)2 as 0.6:1 at room temperature.

Influences of Solifluction and Sediment Runoff on the Stream Water Qualities in the Northeastern Area of Bukhansan National Park (북한산국립공원(北漢山國立公園) 북동사면(北東斜面)에서 동결융해침식(凍結融解浸蝕) 및 토사유출(土砂流出)이 계류수질(溪流水質)에 미치는 영향(影響))

  • Park, Jae Hyeon
    • Journal of Korean Society of Forest Science
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    • v.90 no.4
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    • pp.513-523
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    • 2001
  • This study was conducted to investigate influences of solifluction and sediment runoff on the stream water qualities during the spring season. The study sites were four points in the northeastern area of the Bukhansan National Park. And, field surveys were carried out in the spring of 1999, 2000 and 2001. The results of this study were summarized as follows; During the investigation period, the amounts of sediment caused by solifluction on stream side slopes in the downstream were 1.3~1.7 times as large as those in the upstream. The pH of sediment caused by solifluction was a potential influence on the pH of stream water. Amounts of dissolved $Cl^-$, $NO_3{^-}$ and $SO{_4}^{2-}$ in stream water were proportion to the average amounts of $Cl^-$, $NO_3{^-}$ and $SO{_4}^{2-}$ in the sediment caused by solifluction. In the spring, the average pH of stream water was lower than the first class of the river water quality standard because of increasing chemical concentration as well as the contents of anions($Cl^-$, $NO_3{^-}$ and $SO{_4}^{2-}$) in the spring season. Also, the average electrical conductivity of water in downstream was about 2.3-3.3 times higher than that in upstream. The amounts of anions($Cl^-$, $NO_3{^-}$ and $SO{_4}^{2-}$) of water in downstream were about 1.2~7.4, 1.1~3.9, 1.1~1.4 times higher than those in upstream, respectively. Therefore, these results showed that the water quality of downstream was worse than that of upstream. As a result of regression analyses, the linear and exponential equation of pH and water quantity was pH = 1.7926 ${\times}$ stream water quantity + 5.9577($R^2=0.46$), and those of electrical conductivity and water quantity was $EC=34.417e^{3.6334{\times}\text{stream water quantity}(m^3/sec)}$ ($R^2=0.44$).

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Weed Competition and Herbicide Response of Rice under the Foggy Condition II. Growth and Weed Competition of Rice (안개조건하(條件下)에서 벼(Oryza sativa L.)의 잡초경합(雜草競合)과 제초제(除草劑) 반응차이(反應差異)에 관(關)한 연구(硏究) II. 벼의 생장(生長)과 잡초경합(雜草競合))

  • Guh, Ja-Ock;Lee, Min-Soo;Kuk, Yong-In;Chon, Sang-Uck
    • Korean Journal of Environmental Agriculture
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    • v.14 no.2
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    • pp.221-231
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    • 1995
  • The objectives of the present study were to find out the differences in growth and weed competition of rice under the foggy and non-foggy condition, and finally, the fundamental data for the establishment of the paddy weed control system under the locational foggy regions. The research was carried out on tin trays ($0.12m^2$) in greenhouse equipped with an Auto Foggy System(SAE KI RTN Co.). The results are summarized as follows: Exp. I. Difference in rice growth under the foggy and non-foggy condition. 1. While the plant height was not affected, the number of tillers was decreased by the foggy condition. The ratio of the number of effective tiller, however, became higher under the foggy condition. 2. Due to the fog present, the heading rate was decreased and heading time was delayed. 3. The foggy condition did not affect the dry weight of rice straw whether they were grown under the foggy or non-foggy condition. However, yield components such as the number of ears, the number of grains per ear, thousand kernel weight and percentage of ripeness were reduced. Particularly, weights of perfect brown and unpolished rice were also decreased. Exp. II. Effect of the duration of competition between weed and rice grown under the foggy condition on the growth of rice plant. 1. There was no difference in the height of rice grown under a different duration of competition. There was a clear tendency that the number of tillers of rice grown under the foggy condition was decreased as the duration of competition was decreased. 2. When the duration of competition was longer than 60 days, the heading rate was decreased and the initiation of heading was also delayed by 2-4 days. 3. Under the foggy condition, the duration of competition for more than 40 days affected dry weight of rice straw and the difference in yield was greatest in the non-competition and competition for more than 40 days.

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p53 and K-ras Expression in Interstitial Lung Disease (간질성 폐질환에서 p53 및 K-ras 암표지자의 발현)

  • Oh, In-Jae;Kim, You-Il;Kim, Kyu-Sik;Yoo, Young-Kwon;Kim, Soo-Ok;Lee, Eun-Woo;Lim, Sung-Chul;Kim, Young-Chul;Park, Kyung-Ok;Park, Chang-Soo
    • Tuberculosis and Respiratory Diseases
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    • v.51 no.3
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    • pp.201-210
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    • 2001
  • Background : Approximately 10-13% of patients with interstitial lung disease(ILD) die of lung cancer, and patients with ILD have been reported to have a 7 fold higher incidence of lung cancer compared to the normal population. Recently, overexpression of the p53 and p21 proteins were observed in the epithelial cells from pathologic specimens of ILD. Overexpression of these proteins may result from chronic or recurrent DNA damage by unknown causes of inflammation. However, these proteins may also contribute to oncogenesis if other genetic alterations such as K-ras are superimposed. Methods : Immunohistochemical stains for p53 and K-ras proteins were performed with pathologic specimens from 38 cases with ILD(M/F : 27/11, mean agea : $54{\pm}10$ years) and from 10 control subjects. Results : The p53 protein was expressed in 21.1% (8/38 ILD cases) and K-ras protein expression was observed in 65.8% (25/38 ILD cases). However, neither p53 nor the K-ras protein staining was observed in the control subjects. Conclusion : A significant proportion of cases with ILD expressed the p53 and K-ras proteins in their bronchial epithelial cells. These proteins may be potentially oncogenic with the addition of further genetic alterations. However, to clarify the significance of these findings, further studies looking for correlations with the incidence of lung cancer and other genetic changes are needed.

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A Comparative Study of the Foreign Trade Strategies of Gaisong Merchants and Modern Companies in Korea. (현대기업과 개성상인의 해외진출전략의 비교분석)

  • Park, Sang-Gyu
    • Korean Business Review
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    • v.17
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    • pp.153-183
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    • 2004
  • The Gaisong Merchants can be regarded to playa pioneering role to activate the Korea's trade with foreign countries. In the early period of Yi-Dynasty, the Gaisong Merchants focused on personal trade, but in the middle period of Yi-Dynasty, they entered to the realm of governmental trade. Furthermore, their business activities widened to various forms of trades, for example, smuggling. Utilizing accumulated capital, Gaisong merchants expanded their trading activities to their neighboring countries such as Japan and China. In recent times, it is necessary for modem Korean companies to diversify risks through the establishment of corporations for production, marketing and R&D abroad or through joint venture, M&A and strategic alliance with foreign companies in order to reduce the risks originated from volatile economic and political situations. In this study, we utilize tools of comparative study to compare Gaisong Merchants' foreign trade strategies with those of modem companies such as AMOREPACIFIC, HANILCEMENT and SHINDORICO. The purpose of the paper is to test the hypothesis that modem Korean companies grew up by following the cases of Gaisong Merchants' business activities. We summarize our main findings as follows. First, both Gaisong Merchants and modem Korean companies have common functional core capability in the field of marketing, manufacturing technology, R&D, and human resources development. Second, both Gaisong Merchants and modem Korean companies have common organizational core capability. Third, both Gaisong Merchants and modem Korean companies have common infrastructures such as planning, finance, accounting and MIS. It constitutes the infrastructure of Korea's foreign trade sector. Fourth, both Gaisong Merchants and modem companies have common organizational culture in the field of management policy and philosophy. Actually, those factors are evaluated to be driving forces of Koera's success in foreign trade. In conclusion, the business activities of Gaisong Merchants who represented the peculiarity of Korean business spirit are partially inherited to current Korean business management. The value system and behavior pattern of modern Korean companies is succeeded from the spirit of Gaisong Merchants and it playa major role to specify the identity of Korean business administration.

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A study of the arch length discrepancy and the diagnostic analysis (치열궁내 공간 부조화와 진단적 평가에 관한 연구)

  • Ryu, Young-Kyu;Ahn, Kwang-Seok
    • The korean journal of orthodontics
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    • v.34 no.1 s.102
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    • pp.1-11
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    • 2004
  • Predicting the arch length discrepancy by simply comparing the available arch perimeter with tooth materials is merely a 2-dimensional analysis of the teeth movement. However, the real teeth movement takes place 3-dimensionally and is affected by various factors such as, the arch fen the curve of Spee and the axis of the incisors. The purpose of this study is to clarify the relationship between the decrease in the arch perimeter and the horizontal positional change of the incisors after extraction of the 1st bicuspids, for more analytic evaluation of the arch length discrepancy at pre-treatment model analysis stage. In addition to that to evaluate the effect of the curve of Spee, teeth axis to the basal plane, and the incisional crowding to the treatment outcome. All patients were treated at the department of orthodontics, dental hospital, Yonsei university. Inclusion criteria for patients selection were as follows. $\cdot$ Angle classification I malocclusion with bialveolar protrusion $\cdot$ Extraction of 4 1st bicuspids $\cdot$ No tooth anomaly or prosthesis $\cdot$ No abnormal attrition $\cdot$ No ectopically erupted teeth $\cdot$ Angle classification I canine and molar relationship $\cdot$ Less than 3mm of crowding Model analysis of the above patients was performed and the following conclusions were obtained. 1. When the intercanine distance was maintained, the available space for the distal movement of the mandibular incisors after the extraction of the 4 1st bicuspids was larger than the space provided by the extraction of the 4 1st bicuspids. However the difference was less than 1mm. The more tapered the anterior arch form, the larger the difference. 2. Compared to the situation in which the intercanine distance was maintained, when the intercanine distance was expanded to meet the width of the Posterior teeth, the incisors could move about 3mm more distally. 3. The positional difference of the incisal tip was insignificant whether the central incisors were moved by tipping or bodily movement. 4. When the anterior crowding was solved without changing the intercanine distance, the larger the anterior arch length was, the more the anterior movement of the incisors. 5. When the curve of Spee was levelled, the increase in the arch perimeter was less than half of the deepest curve of Spee.