• Title/Summary/Keyword: M/I ratio

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Accuracy Evaluation of CT-Based Attenuation Correction in SPECT with Different Energy of Radioisotopes (SPECT/CT에서 CT를 기반으로 한 Attenuation Correction의 정확도 평가)

  • Kim, Seung Jeong;Kim, Jae Il;Kim, Jung Soo;Kim, Tae Yeop;Kim, Soo Mee;Woo, Jae Ryong;Lee, Jae Sung;Kim, Yoo Kyeong
    • The Korean Journal of Nuclear Medicine Technology
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    • v.17 no.1
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    • pp.25-29
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    • 2013
  • Purpose: In this study, we evaluated the accuracy of CT-based attenuation correction (AC) under the conventional CT protocol (140 kVp, on average 50-60 keV) by comparing the SPECT image qualities of different energy of radioisotopes, $^{201}Tl,\;^{99m}Tc$ and $^{131}I$. Materials and Methods: Using a cylindrical phantom, three different SPECT scans of $^{201}Tl$ (70 keV, 55.5 MBq), $^{99m}Tc$ (140 keV, 281.2 MBq) and $^{131}I$ (364 keV, 96.2 MBq) were performed. The CT image was obtained with 140 kVp and 2.5 mA in GE Hawkeye 4. The OSEM reconstruction algorithm was performed with 2 iterations and 10 subsets. The experiments were performed in the 4 different conditions; non-AC and non-scatter correction (SC), only AC, only SC, AC and SC in terms of uniformity and center to peripheral ratio (CPR). Results: The uniformity was calculated from the uniform whole region in the reconstructed images. For $^{201}Tl$ and $^{99m}Tc$, the uniformities were improved by about 10-20% AC was applied, but these were decreased by about 2% as SC was applied. The uniformity of $^{131}I$ was slightly increased as both AC and SC were applied. The CPR of the reconstructed image was close to one, when AC was applied for $^{201}Tl$ and $^{99m}Tc$ scans and $^{131}I$ was distant from 1 and that is only AC. Conclusion: The image uniformity improved by AC on low energy likely to $^{201}Tl$ and $^{99m}Tc$. However, image uniformity of high energy such as $^{131}I$ was improved, when both AC and SC was applied.

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Parametric Study on the P-M Interaction Diagram of Hollow Prestressed Concrete Bridge Columns (중공 프리스트레스트 콘크리트 교각의 P-M 상관도 매개변수 분석)

  • Kim, Tae-Hoon
    • Journal of the Earthquake Engineering Society of Korea
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    • v.15 no.6
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    • pp.1-10
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    • 2011
  • This study presents the results of parametric studies of the P-M interaction diagram of hollow prestressed concrete bridge columns. Among the numerous parameters, this study concentrates on concrete compressive strength, prestressing steel reinforcement ratio, effective prestress, the Ds/Do ratio, and the Di/Do ratio. The strength and ductility of hollow prestressed concrete bridge columns were evaluated through quasistatic tests. The P-M interaction diagrams from the codes were different from that of the results, which were in good agreement with AASHTO-LRFD. Nondimensionalized P-M interaction diagrams were developed to predict the design resistance of hollow prestressed concrete bridge columns.

Size Distribution and Concentration of Airborne Fungi in the Public Facilities (다중이용시설 내부에 분포하는 부유 진균의 입경별 농도 특성)

  • Park, Jae-Beom;Kim, Ki-Youn;Jang, Gyu-Yeob;Kim, Chin-Yon;Lee, Kyung-Jong
    • Journal of Environmental Health Sciences
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    • v.32 no.1 s.88
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    • pp.36-45
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    • 2006
  • The aim of this study is to examine size-based concentration and genera of airborne fungi distributed in public facilities such as hospital, kindergarten, day-care center and postpartum nurse center and to provide fundamental data in order to prevent respiratory diseases caused by exposure to airborne fungi. Culturable total and respirable concentrations of airborne fungi averaged to $382\;cfu/m^3\;and\;292\;cfu/m^3$ in hospital, $536\;cfu/m^3\;and\;347\;cfu/m^3$ in kindergarten, $334\;cfu/m^3\;and\;266\;cfu/m^3$ in day-care center, and $371\;cfu/m^3\;and\;289\;cfu/m^3$ in postpartum nurse center, respectively. The ratio of respirable to total concentration of airborne fungi in the investigated public facilities was ranged from $55\%\;to\;70\%$ but there was no significant difference among them (p>0.05). The mean I/O ratio of culturable total and respirable concentrations were 0.56 and 0.64 in hospital, 0.72 and 0.91 in kindergarten, 0.33 and 0.45 in day-care center, and 0.63 and 0.73 in postpartum nurse center, respectively. Indoor concentration of airborne fungi did not correlated significantly with indoor temperature and relative humidity (p>0.05) but had a significant positive correlation with $CO_2$ concentration (p<0.01) and surrounding condition (p<0.05). Penicillium spp., Cladosporium spp., and Aspergillus spp. were estimated to over $95\%$ of total airborne fungi identified in the investigated public facilities.

Pharmacokinetic profiles of levofloxacin after intravenous, intramuscular and subcutaneous administration to rabbits (Oryctolagus cuniculus)

  • Sitovs, Andrejs;Voiko, Laura;Kustovs, Dmitrijs;Kovalcuka, Liga;Bandere, Dace;Purvina, Santa;Giorgi, Mario
    • Journal of Veterinary Science
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    • v.21 no.2
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    • pp.32.1-32.13
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    • 2020
  • Levofloxacin pharmacokinetic profiles were evaluated in 6 healthy female rabbits after intravenous (I/V), intramuscular (I/M), or subcutaneous (S/C) administration routes at a single dose of 5 mg/kg in a 3 × 3 cross-over study. Plasma levofloxacin concentrations were detected using a validated Ultra Performance Liquid Chromatography method with a fluorescence detector. Levofloxacin was quantifiable up to 10 h post-drug administration. Mean AUC0-last values of 9.03 ± 2.66, 9.07 ± 1.80, and 9.28 ± 1.56 mg/h*L were obtained via I/V, I/M, and S/C, respectively. Plasma clearance was 0.6 mL/g*h after I/V administration. Peak plasma concentrations using the I/M and S/C routes were 3.33 ± 0.39 and 2.91 ± 0.56 ㎍/mL. Bioavailability values, after extravascular administration were complete, - 105% ± 27% (I/M) and 118% ± 40% (S/C). Average extraction ratio of levofloxacin after I/V administration was 7%. Additionally, levofloxacin administration effects on tear production and osmolarity were evaluated. Tear osmolarity decreased within 48 h post-drug administration. All 3 levofloxacin administration routes produced similar pharmacokinetic profiles. The studied dose is unlikely to be effective in rabbits; however, it was calculated that a daily dose of 29 mg/kg appears effective for I/V administration for pathogens with MIC < 0.5 ㎍/mL.

Phase Separation Characteristics via Bunsen Reaction in Sulfur-Iodine Thermochemical Hydrogen Production Process (SI 열화학 수소 제조 공정에서 분젠 반응을 통한 상 분리 특성)

  • Lee, Kwang-Jin;Kim, Young-Ho;Park, Chu-Sik;Bae, Ki-Kwang
    • Transactions of the Korean hydrogen and new energy society
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    • v.19 no.5
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    • pp.386-393
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    • 2008
  • The Sulfur-iodine(SI) thermochemical cycle is one of the most promising methods for massive hydrogen production. For the purpose of continuous operation of SI cycle, phase separation characteristics into two liquid phases ($H_2SO_4$-rich phase and $HI_x$-rich phase) were directly investigated via Bunsen reaction. The experiments for Bunsen reaction were carried out in the temperature range, from 298 to 333 K, and in the $I_2/H_2O$ molar ratio of $0.109{\sim}0.297$ under a continuous flow of $SO_2$ gas. As the results, solubility of $SO_2$, decreased with increasing the temperature, had considerable influence on the global composition in the Bunsen reaction system. The amounts of impurity in each phase(HI and $I_2$ in $H_2SO_4$-rich phase and $H_2SO_4$ in $HI_x$-rich phase) were decreased with increasing $H_2SO_4$ molar ratio and temperature. To control the amounts of impurity in $HI_x$-rich phase, temperature is a factor more important than $I_2/H2_O$ molar ratio. On the other hand, the affinity between $HI_x$ and $H_2O$ was increased with increasing $I_2/H2_O$molar ratio.

Characteristics of Speech Intelligibility and the Vowel Space in Patients with Parkinson's disease (파킨슨병 환자의 말 명료도와 모음 공간 특성)

  • Shim, Hee-Jeong;Park, Won-Kyoung;Ko, Do-Heung
    • Phonetics and Speech Sciences
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    • v.4 no.3
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    • pp.161-169
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    • 2012
  • The purpose of this study was to investigate the characteristics of speech intelligibility of spontaneous speech and the vowel space parameters in patients with Parkinson's disease. Ten PD patients (M=5, F=5) and a corresponding control group of ten normal adults participated in this study. Firstly, subjects were asked to tell a story about their hometown and youth in order to analyze speech intelligibility. Secondly, the subjects were also asked to repeat four vowels (/a/, /i/, /u/, /e/) five times in order to compare their vowel spaces. The results were as follows: (1) the speech intelligibility of the PD group was lower than that of the control group. (2) Four parameters including vowel area, vowel articulatory index, formant centralization ratio, F2i/F1u ratio were significantly different in each group. For instance, vowel area and F2 ratio were wider and higher, respectively. As a result, a decrease in speech intelligibility of patients with PD is likely to show different types of errors from the normal group. The results of this research are meaningful in a sense that they could provide the objective standard of speech intelligibility and vowel space parameters.

Nitric oxide modulates antioxidant defense and the methylglyoxal detoxification system and reduces salinity-induced damage of wheat seedlings

  • Hasanuzzaman, Mirza;Hossain, Mohammad Anwar;Fujita, Masayuki
    • Plant Biotechnology Reports
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    • v.5 no.4
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    • pp.353-365
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    • 2011
  • The present study investigates the possible regulatory role of exogenous nitric oxide (NO) in antioxidant defense and methylglyoxal (MG) detoxification systems of wheat seedlings exposed to salt stress (150 and 300 mM NaCl, 4 days). Seedlings were pre-treated for 24 h with 1 mM sodium nitroprusside, a NO donor, and then subjected to salt stress. The ascorbate (AsA) content decreased significantly with increased salt stress. The amount of reduced glutathione (GSH) and glutathione disulfide (GSSG) and the GSH/GSSG ratio increased with an increase in the level of salt stress. The glutathione S-transferase (GST) activity increased significantly with severe salt stress (300 mM). The ascorbate peroxidase (APX), monodehydroascorbate reductase (MDHAR), dehydroascorbate reductase (DHAR), catalase (CAT) and glutathione peroxidase (GPX) activities did not show significant changes in response to salt stress. The glutathione reductase (GR), glyoxalase I (Gly I), and glyoxalase II (Gly II) activities decreased upon the imposition of salt stress, especially at 300 mM NaCl, with a concomitant increase in the $H_2O_2$ and lipid peroxidation levels. Exogenous NO pretreatment of the seedlings had little influence on the nonenzymatic and enzymatic components compared to the seedlings of the untreated control. Further investigation revealed that NO pre-treatment had a synergistic effect; that is, the pre-treatment increased the AsA and GSH content and the GSH/GSSG ratio, as well as the activities of MDHAR, DHAR, GR, GST, GPX, Gly I, and Gly II in most of the seedlings subjected to salt stress. These results suggest that the exogenous application of NO rendered the plants more tolerant to salinity-induced oxidative damage by enhancing their antioxidant defense and MG detoxification systems.

Reactive Dyeing in Immiscible Two-phase System of Water/Organic Solvent (II) - The Dyeing of Silk with C. I. Reactive Blue 203 - (물/유기용매 불혼합 이성분계에서의 반응염색(II) - C. I. Reactive Blue 203을 이용한 견섬유의 염색 -)

  • 김태경;김미경;임용진;조광호
    • Textile Coloration and Finishing
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    • v.13 no.2
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    • pp.128-134
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    • 2001
  • Following the prior studs regarding that 1.0g of cotton fabric round be dyed uniformly with a reactive dye in the solvent mixture of $2m\ell$ of water and $23m\ell$ of dichloromethane, silk fabric was dyed with C. I. Reactive Blue 203 in the water/dichloromethane two-phase immiscible solvent media. In order to minimize dye loss due to its hydrolysis, the reactive dyeing was carried out in dichloromethane containing a small amount of water. With only $3m\ell$ of water in $22m\ell$ of dichloromethane, 1.0g of silk fabric could be dyed perfectly. The uptake ratio was increased greatly, compared wish that of normal reactive dyeing in a water medium. It would seem that the one of hydrophobic solvents, dichloromethane, can assist the Even dyeing as it disperses a small amount of dye-dissolved phase and conveys this water phase to the fabric entirely and uniformly.

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Hydrolytic Behavior of Vinylsulfonyl Reactive Dyes - Easiness of Dimerization -

  • Kim, In Hoi
    • Textile Coloration and Finishing
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    • v.27 no.1
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    • pp.1-10
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    • 2015
  • The aim of the current study is to identify the dimerization and decomposition kinetics of the F-$D_M$ type. The regeneration of F-VS from $F_iF_j-D_M$ or the reversibility of the dimerizations were investigated. The order of real rate constants of the dimerization('$K_D{^{ij}}$) would seem to be similar to that of rate constants of a dimerization($K_D{^{ij}}$) for VS dyes at a given pH because of the constancy of the equilibrium constants($K_a{^j}$-value). The reverse reactions of the $D_M$ types are appeared to occur in two steps, the deprotonation of ${\alpha}$-carbon of the $D_M$ types and disproportionation. The ratio of the decomposition of the $D_M$ type to F-Hy and F-VS appears to be related with the ratio of $K_i/K_j$. Similarities were also found among various other reactions, including homo- and mixed dimerization. VS dyes undergoing fast hydrolysis have difficulty in forming a dimer. The higher the reactivity with cellulose or hydroxide ion, the smaller the dimerization. The easiness of the dimerization was thus found to be inversely proportional to the rate of hydrolysis.

Control the crystal size by varying concentrations of precursors for the planar perovskite solar cells

  • Xie, Lin;Hwang, Heewon;Kim, Minjung;Kim, Kyungkon
    • Rapid Communication in Photoscience
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    • v.4 no.4
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    • pp.79-81
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    • 2015
  • The influence of the grain size of the $CH_3NH_3PbI_3$ on the solar cell performance is investigated by controlling the ratio between $CH_3NH_3I$ and $PbI_2$ precursors. As the concentration of the precursors increased from 1.0M to 2.0M, the $CH_3NH_3PbI_3$ grain size increased from ~100nm to ~400nm. The solar cell utilizing the $CH_3NH_3PbI_3$ with large grain size shows improved photocurrent compared to the solar cell utilizing $CH_3NH_3PbI_3$ with small grain size, which is ascribed to the reduced recombination at the boundaries of grains.