• 대한한의학방제학회지
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• 제25권2호
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• pp.303-324
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• 2017

Objectives : Consumptive is an unhealthy condition that are caused by lack of blood and essence, and that means also some stages of chronic diseases. The purpose of this study is to analysis 108 Prescriptions of Consumptive part in Dongui Bogam. Methods : The 108 Prescriptions of Consumptive part in Dongui Bogam analysed frequency of basic prescriptions, symptoms of prescriptions and the pathology. Results : Ssangbohwan, Yiuihwan, Gamrihwan were used for tonifying were mostly used as basic prescriptions in whole Consumptive part respectively. There are common symptoms in consumptive part in Dongui Bogam. That symptoms are "tidal fever, night sweating, nocturnal emission, cough, sputum, skinny body, weak pulse, spontaneous sweating, deafness, dim vision and tuberculosis". Qi blood(yin yang) pathologies in prescriptions on consumptive part are "yin deficiency, yin deficiency with effulgent fire, yang qi deficiency, dual damage of qi and blood, non-interaction between fire and water, collapse of yang and exhaustion of yin, less blood". viscera and bowels pathologies in prescriptions on consumptive part are "heart and kidney deficiency, spleen-stomach weakness, spleen and kidney great deficiency, weakness of kidney qi, meridian waste in heart, spleen and kidney, damage in heart and lung". Conclusions : As a result of Study on Analysis all Prescriptions of Consumptive part in Dongui Bogam, We can understand more about basic prescriptions, symptoms of prescriptions and the pathology that are using for curing consumptive. We expected that this study will can help to give rationale for future study of consumptive caring.

• 대한한의학원전학회지
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• 제22권4호
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• pp.189-198
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• 2009

Considering the opinions of annotators, the remedy about excess of east and deficiency of west from "the seventy-fifth question" can be arranged as follows. "The seventy-fifth question", with "the sixty-ninth question", explains excess and deficiency of mother and son. Abatement of fire and invigoration of water[瀉火補水] in the excess of wood and deficiency of metal[木實金虛] presents a remedy, which has been applied in herbs and medicine application henceforth. "The seventy-fifth question" is a unique theory from " Nan-gyeong(難經)", and does not continue the theory of "Hwangjenaegyeong(黃帝內經)". "The seventy-fifth question" mentions the relationship of excess and deficiency of the five elements and five viscera, but does not mention excess and deficiency of invigoration and abatement of the meridian. Remedy from abatement of fire and invigoration of water[瀉火補水] in the excess of wood and deficiency of metal[木實金虛] is an abnormal, temporary and extraordinary method. This remedy is applied in Saam acupuncture[舍巖鍼] as A-variation form. The process where Son allows excess of mother[子能令母實] and mother allows deficiency of son[母能令子虛] in the abatement of fire and invigoration of water[瀉火補水] is a mechanism, not a remedy. Generation after generation, medical practitioners can be classified into those that claimed abatement of fire and invigoration of water[瀉火補水] because of the relation with excess of liver and deficiency of lung[肝實肺虛], abatement of heart(瀉心) due to the excess of liver(肝實), or invigoration of Eum and abatement of Yang[補陰瀉陽].

• 대한한의학방제학회지
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• 제20권2호
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• pp.137-151
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• 2012

Objectives : provides the basis on steaming processing method (SPM) which was stated in 'Dongeuibogam' and 'Euihakipmun'. Methods : Drugs and prescriptions listed in 'Dongeuibogam' and 'Euihakipmun' were investigated by following criteria; (i) name and prescription of SPM-applied drugs, (ii) protocols on the use of the supporting materials, (iii) kind of supporting materials, (iv) processing period, (v) part of the herb plants, (vi) efficacy of herbal drugs, (vii) tastes of herbal drugs, (viii) meridian tropism of the herbal drugs. Results : 1. The number of herbs was 92 species of from 'Dongeuibogam', 87 from 'Euihakipmun', and the number of prescriptions was 197 from 'Dongeuibogam' and 119 from 'Euihakipmun'. 2. Infiltrating steaming and mixing and steaming procedures were used to process supporting materials. 3. The abundance of supporting materials was in the order of alcohol and ginger juice. 4. A twelve hour-period was most frequently used. 5. The herbal parts used most were in the order of fruit, seed, roots, and stem. 6. According to an efficacy category, a drug supplementing invigoration was used most frequently and a drug eliminating heat followed next. 7. Based on four spirit features, herbs showing warm, cold, and mild features were used most. 8. In considering five tastes, herbs showing sweet and bitter tastes were used most. 9. The herbs supporting the function of liver, kidneys, spleen, stomach, and lung were used in SPM. The herbs converging to the kidneys and the liver were conducted most in 'Dongeuibogam' and 'Euihakipmun' respectively. No case for herbal drug converging to 'Samcho' was reported. Conclusions : Our investigation on the use of SPM from 'Dongeuibogam' and 'Euihakipmun' revealed that there are special principles underlying the use of supporting materials, SPM period, parts and efficacy.

• Korean Journal of Acupuncture
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• 제20권3호
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• pp.115-128
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• 2003

Objectives and methods :　Study the anti-cancer, anti-metastasis and immune response improvement effects of Herbal-acupuncture with Evodiae Fructus infusion solution, we injected Evodiae Fructus infusion solution into Zusanli(St36) of C57BL/6 mouse which is corresponding to human Zusanli(St36). We observed its effect on the number of $CD25^+/CD4^+,\;CD8^+/CD3e^+,\;CD69^+/B220^+,\;NK1.1^+/CD3e^+$ cells in mouse PBMCs, the number of the pulmonary colony , MST and ILS of C57BL/6 mice implanted intravenously with B16-F10 melanoma. Results and Conclusions : The spleen cells proliferation of the sample groups treated with EDR-HAS extract has increased significantly compared with that of the control group. The percentage of the $CD25^+/CD4^+,\;CD8^+/CD3e^+,\;CD69^+/B220^+,\;NK1.1^+/CD3e^+$ cells in C57BL/6 mouse PBMCs of the sample groups treated with EDR herbal-acupuncture has increased compared with that of the control group. The lung colony number of the sample groups treated with EDR herbal-acupuncture has decreased significantly compared with that of the control group. MST and ILS of the sample groups treated with EDR herbal-acupuncture have increased significantly compared with those of the control group.

• 한방안이비인후피부과학회지
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• 제16권3호
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• pp.1-37
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• 2003

The epistaxis is commonplace and temporary disease in the field of ENT. In most cases, it is a slight illness, but sometimes, it leads to death because of copious bleeding. The first treatment of epistaxis is stoping hemorrhage, but the real state of treatment in oriental medical is not thoroughgoing enough. So we referred to oriental medical journals and sundry records about etiology and remedy of epistaxis, we got this results. 1. The etiology of epistaxis was mostly bleeding due to heat in the blood by dysfunction of Jang and Bu Gi, there were affection wind-cold by exopathogen, spleen heat to liver, excessive fire of lung meridian, stagnated fire-heat of upper Cho, excessive drinking, bruise and so on. 2. The treatment was used much to remove heat from the blood and activating blood, in case of getting no better, it's used to enriching the blood or clear Gi. 3. The internal remedy of epistaxis was the most used 20times SeogakJihwangtang(犀角地黃湯) to remove heat from the blood and activating blood, and used Jihwangtang(地黃湯), Samhwangbohyultang(三黃補血湯), Jiyuksan(止육散), hueksinsan(黑神散), etc. The drugstuffs were the most used 51times Radix Rehmanniae Preparata((生地黃) to clear heat and remove heat from the blood, produce the body fluids, yin, and used Radix Paeoniae Alba(芍樂) and Radix Glycyrrhizae(甘草), Radix Angelicae Gignatis(當歸), Radix Scutellariae(黃岑), Rhizoma Coptidis(黃連) and Fructus Gardeniae(梔子), etc. 4. The external medical treatment of epistaxis was the most used 16times spraying the granular medication into the cavity and attaching Allii Bulbus(大蒜) to center of the sole or binding the middle finger, etc.

• 혜화의학회지
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• 제9권1호
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• pp.423-442
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• 2000

Objectives : The objectives of this study is to find out the classification methods of the cause of disease and the Acupuncture points on the cough(咳嗽, hae-soo) from the oriental medical literature. The results obtained as follows. Methods : We surveyed the oriental medical books from Hung-Ti-Nei-Ching $\ll$黃帝內經$\gg$ to recent books concerning the Acupuncture therapy for the cough(咳嗽, hae-soo). Results : 1. There are the classification methods of the cause of the cough(咳嗽, hae-soo) by affection by exopathogen and internal injury, by five zang-organs and six fu-organs, by time-belt, and by cold and heat. 2. The acupuncture points at P'yesu(肺兪, BL13), T'aeyon(太淵, LU9), Ch'okt'aek(尺澤, LU5), P'ungmun(風門, BL12), Yolgyol(列缺, LU7), Ch'ondol(天突, CV22), Taech'u(大椎, GV14), Hapkok(合谷, LI4), Kohwang(BL43), T'aegye(太谿, KI3), Chok-samni(足三里, ST36) are most frequently used on the acupuncture therapy for the cough(咳嗽, hae-soo). Conclusions : Among the classification methods of the cause of the cough(咳嗽, hae-soo), the classification methods by affection by exopathogen and internal injury may be most effective and the acupuncture points at Lung meridian(手太陰肺經, LU), Bladder mendian(足太陽膀胱經, BL) are most frequently used on the acupuncture therapy for the cough(咳嗽, hae-soo).

• 한방재활의학과학회지
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• 제31권1호
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• pp.59-79
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• 2021

Objectives This study was performed to observe the genotoxic effect of the ChondroT. Methods To evaluate the genotoxicity of ChondroT, an experiment of bacterial reverse mutation test, in vitro mammalian chromosomal aberration test and mammalian erythrocyte micronucleus test in mouse was conducted. Results TA98, TA100 and TA1537 strains in the absence of metabolic activation system (S9 mix), the number of revertant colonies being greater than 2-fold of the respective negative control value. Both in -S9 mix and +S9 mix, the frequencies of aberration cells with structural aberration and numerical aberrations of chromosome were less than 5%. There was no increase of polychromatic erythrocyte with one or more micronuclei at any dose of test substance compared to the negative control group (p<0.05). Conclusions In TA98, TA100 and TA1537 strains in the absence of metabolic activation system (S9 mix), the number of revertant colonies was greater than 2-fold of the respective negative control value, showing positive results. ChondroT was considered to be non-clastogenic to Chinese hamster lung (CHL/IU) cells under the present experimental condition. and ChondroT was determined not to induce an increased frequency of micronuclei in the bone marrow cells of male ICR mice under the present experimental condition.

• 대한한의학원전학회지
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• 제37권1호
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• pp.1-24
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• 2024

Objectives : The objective of this study is to compare the properties of Mahuang and Shigao based on their similar effects and how they are manifested in formulas that include these medicinals. Methods : Descriptions of Mahuang and Shigao as written in the Shennongbencaojing, Mingyibielu, Bencaogangmu, Benjingshuzheng were analyzed to determine their similar traits. Formulas in which these medicinals were both used for their similar effects were analyzed. Results & Conclusions : Mahuang and Shigao, through their interaction, both communicate fluids, relieve stagnation, and draw out heat or Yang qi from the Yin part. These similarities influence each other, which is related to their common meridian tropism, the Lung Channel, to diffuse, purify and descend. The ten formulas that include the two medicinals were similar in that Yin and Yang were interactive. Of these, those that relieved stagnation were Maxingganshitang and Daqinglongtang. Those which communicated fluids and relieved stagnation were Yuebitang, Yuebijiabanxiatang, Yuebijiashutang, Xiaoqinglongjiashigaotang, Houpumahuangtang, and Wengetang. Those that drew out heat or Yang qi from the Yin part through interaction between Yin and Yang were Guizhieryuebiyitang and Mahuangshengmatang. Previous studies stated that Mahuang and Shigao are different and using both medicinals in the same formula would repress each other or balance each other out-this study focused on their common properties which resulted in the above-mentioned findings.

• 대한본초학회지
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• 제39권3호
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• pp.11-21
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• 2024

Objective : For the purpose of developing Korean Primulaceae plants, the literature published so far have been thoroughly investigated to prepare this article. Methods : Books and research papers about Herbology which published at Korea and other countries were examined. Results : The results of this study were as follows: 1. A total of 8 genera and 30 species of Primulaceae was found in the Korea, among which 4 genera and 9 species (approximately 30%) were medicinal plants. 2. Among Korean Primulaceae plants, Lysimachia was the most with 11 species. 3. Among medicinal plants, Lysimachia was the most with 5 species, followed by 1 species of Anagallis, 1 species of Primula, and 2 species of Androsace. 4. The domestic distribution of medicinal plants was 4 species in the north part, 7 species in the central part, 7 species in the south part, and 7 species in Jeju island. 5. Among the medicinal parts, the whole body was used the most with 9 species. Among the property flatness property was the most whith 10 species. And among the flavors, bitter taste was the most with 13 species. 6. Lung meridian channel was the most with 3 species. The effect of reducing swelling was the most with 10 species. 7. No toxic drugs have been reported yet. Conclusion : There were totaled to 8 genera and 30 species in Primulaceae in Korea and among them medicinal plants are 4 genera, 9 species, some 30% in total.

• Journal of Acupuncture Research
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• 제22권1호
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• pp.131-144
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• 2005

족삼리(足三里) 사과락약침(絲瓜絡藥鍼)이 DBA/lJ mouse의 collagen-induced arthritis 미치는 영향(影響)을 관찰(觀察) 한 결과(結果), 다음과 같은 결론(結論)을 얻었다. 1. 세포독성(細胞毒性) 측정결과(測定結果), 사과락약침액(絲瓜絡藥鍼液) 1%의 농도(濃度)에서 가장 높은 세포생존률(細胞生存率)이 관찰(觀察)되었다. 2. In vitro screening 결과(結果), 사과락약광액(絲瓜絡藥鑛液) 1%의 농도(濃度)에서 CIA mouse 관절활막세포(關節滑膜細胞)의 TNF-${\alpha}$발현(發現)이 유의(有意)하게 감소(減少)하였다. 3. 족삼리(足三里) 사과락약침(絲瓜絡藥鍼)에 의하여 관절염(關節炎) 발병률(發病率)이 감소(減少)하였다. 4. 족삼리(足三里) 사과락약침(絲瓜絡藥鍼)에 의하여 CIA mouse의 각장(脚臟)무게가 감소(減少)하였다. 5. 족삼리(足三里) 사과락약침(絲瓜絡藥鍼)에 의하여 CIA mouse의 혈청(血淸) IL-6, INF-${\gamma}$, TNF-${\alpha}$, IgG, IgM 및 Anti-collagen Ⅱ가 유의(有意)하게 감소(減少)하였다. 6. 조직학적(組織學的) 검사(檢査) 결과(結果), 족삼리(足三里) 사과락약침(絲瓜絡藥鍼)에 의하여 CIA mouse 관절(關節)의 연골파괴(軟骨破壞)와 활막증식(滑膜增殖)이 감소(減少)되고 교원질섬유(膠原質纖維)가 정상군(正常群)과 유사(類似)하게 유지(維持)되었다. 7. 임파절내(淋巴節內) CD3e+와 CD19+세포(細胞) 비율(比率), CD4+와 CD8+세포(細胞) 비율(比率)은 사과락약광치료군(絲瓜絡藥鑛治療群)에서 정상군(正常群)과 유사(類似)하게 유지(維持)되었다. 8. 임파절내(淋巴節內) CD69+/CD3e+세포(細胞) 및 CD11a+/CD19+세포(細胞)와 관절내(關節內) CD11b+/Gr-1+세포(細胞)는 사과락약침치료군(絲瓜絡藥鍼治療群)에서 대조군(對照群)에 비하여 유의(有意) 하게 감소(減少)하였다.