• 제목/요약/키워드: Lower bound

검색결과 806건 처리시간 0.027초

전립선암 선별을 위한 PSA 측정의 보험의학적 의미 (Review of measurement of prostate specific antigen: in the aspect of insurance medicine)

  • 박광일
    • 보험의학회지
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    • 제29권1호
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    • pp.16-21
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    • 2010
  • The measurement of prostate specific antigen (PSA) in screening for prostate cancer is recently performed as a routine check-up in clinical medicine and insurance medicine. Several factors may affect serum PSA levels. As prostate size increases with increasing age, the PSA concentration also rises. Increasing body mass index (BMI) is associated with a lower mean PSA concentration. Inhibitors of 5-alpha-reductase such as finasteride and dutasteride produce a 50 percent or greater decrease in serum PSA during the first three months of therapy, which persists as long as the drug is continued. Men who are regularly taking non-steroidal antiinflammatory drugs (NSAIDs) or acetaminophen have lower PSA levels. Emerging concepts regarding PSA testing that may help refine the interpretation of an elevated concentration include: PSA density, PSA velocity, and Free versus complexed or bound PSA. With many insurance companies, PSA level has become part of a standard battery of blood tests, along with HIV, cholesterol, liver enzymes, and other predictors of premature death. But, there is no clear proof of benefit, so we have to monitor the value of PSA test as a prostate cancer screening test in insurance medicine.

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Crack behaviour of top layer in layered rocks

  • Chang, Xu;Ma, Wenya;Li, Zhenhua;Wang, Hui
    • Geomechanics and Engineering
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    • 제16권1호
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    • pp.49-58
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    • 2018
  • Open-mode cracks could be commonly observed in layered rocks. A concept model is firstly used to explore the mechanism of the vertical cracks (VCs) in the top layer. Then the crack behaviour of the two-layer model is simulated based on a cohesive zone model (CZM) for layer interfaces and a plastic-damage model for rocks. The model indicates that the tensile stress normal to the VCs changes to compression if the crack spacing to layer thickness ratio is lower than a threshold. The results indicate that there is a threshold for interfacial shear strength that controls the crack patterns of the layered system. If the shear strength is lower than the threshold, the top layer is meshed by the VCs and interfacial cracks (ICs). When the shear strength is higher than the threshold, the top layer is meshed by the VCs and parallel cracks (PCs). If the shear strength is comparative to the threshold, a combining pattern of VCs, PCs and ICs for the top layer can be formed. The evolutions of stress distribution in the crack-bound block indicate that the ICs and PCs can reduce the load transferred for the substrate layer, and thus leads to a crack saturation state.

Performance Analysis of Pulse Positioning Using Adaptive Threshold Detector (ATD)

  • Chang, Jae Won;Lee, Sang Jeong
    • Journal of Positioning, Navigation, and Timing
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    • 제7권1호
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    • pp.25-35
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    • 2018
  • This paper describes the measurement of pulse positioning (input time) to calculate a time of arrival (TOA) that takes from transmitting a signal from the target of multilateration (MLAT) system to receiving the signal at the receiver. In this regard, this paper analyzes performances of simple threshold method and level adjust system (LAS) method, which is one of the adaptive threshold detector (ATD) methods, among many methods to calculate pulse positioning of signal received at the receiver. To this end, Cramer-rao lower bound (CRLB) with regard to pulse positioning, which was measured when signals transmitted from a transponder mounted at the target were received at the receiver, was induced and then deviation sizes with regard to pulse positioning, which was measured with simple threshold and LAS methods through MATLAB simulations, were compared. Next, problems occurring according to a difference in amplitude of signals inputted to each receiver are described when pulse positioning is measured at multiple receivers located at a different distance from the target as is the case in the MLAT system. Furthermore, LAS method to resolve the problems is explained. Lastly, this study analyzes whether a pulse positioning error occurring due to the signal noise satisfies the requirement (6 nsec. or lower) recommended for the MLAT system when using these two methods.

Capacity Bounds on the Ergodic Capacity of Distributed MIMO Systems over K Fading Channels

  • Li, XingWang;Wang, Junfeng;Li, Lihua;Cavalcante, Charles C.
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제10권7호
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    • pp.2992-3009
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    • 2016
  • The performance of D-MIMO systems is not only affected by multipath fading but also from shadowing fading, as well as path loss. In this paper, we investigate the ergodic capacity of D-MIMO systems operating in non-correlated K fading (Rayleigh/Gamma) channels. With the aid of majorization and Minkowski theory, we derive analytical closed-form expressions of the upper and lower bounds on the ergodic capacity for D-MIMO systems over non-correlated K fading channels, which are quite general and applicable for arbitrary signal-to-noise ratio (SNR) and the number of transceiver antennas. To intuitively reveal the impacts of system and fading parameters on the ergodic capacity, we deduce asymptotic approximations in the high and low SNR regimes. Finally, we pursue the massive MIMO systems analysis for the lower bound and derive closed-form expressions when the number of antennas at BS grows large, and when the number of antennas at transceivers becomes large with a fixed and finite ratio. It is demonstrated that the proposed expressions on the ergodic capacity accurately match with the theoretical analysis.

고 전송률 양자화를 위한 엔트로피 제한 표본 적응 프로덕트 양자기 설계 (Entropy-Constrained Sample-Adaptive Product Quantizer Design for the High Bit-Rate Quantization)

  • 김동식
    • 대한전자공학회논문지SP
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    • 제49권1호
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    • pp.11-18
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    • 2012
  • 본 논문에서는 고 전송률에서도 구현이 가능한 엔트로피 제한(entropy constrained) 벡터양자기를 제안하였다. 양자화는 프로덕트 부호책에 기초한 프로덕트 표본 적응 양자기(sample-adaptive product quantizer)를 사용하여 엔트로피 제한 SAPQ(ECSAPQ) 설계 알고리듬을 제안하고 실험을 통하여 성능을 비교해 보았다. 제안한 ECSAPQ는 비슷한 복잡도의 엔트로피 제한 VQ보다 약 0.5dB 정도 성능이 좋음을 알 수 있었다. 또한 스칼라 양자기에 기초한 ECSAPQ는 Shannon의 최저 왜곡 곡선과 1.53dB의 차이를 가지는 ECSQ의 고 전송률에서의 이론 곡선보다 더 낮은 왜곡 곡선을 가짐을 확인할 수 있었다.

유입수로폭의 조정을 통한 항만부진동 제어 (Control of Seiches by Adjustment of Entrance Channel Width)

  • Yong Jun Cho
    • 한국해안해양공학회지
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    • 제9권2호
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    • pp.57-62
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    • 1997
  • 우리나라 항만의 응답스펙트럼중 상당부분을 설명하는 Helmholtz mode를 중심으로 기운영되고 있는 항만중 정온도 확보에 어려움을 겪고 있는 항만을 대상으로 입사된 파랑에너지의 항내체류시간의 최소화를 통해 경제적 항내정온도 개선책을 모색하고자 고유진동수 등 항만 시스템의 동적특성을 해석하였다. 이를 기초로 항내 정온도 개선책으로 유공방파제 등에 부분적으로 도입되고 있는 에너지 소산 구조를 확대 적용하는 방안과 항만유입수로 폭을 제어수단으로 활용하는 방안을 제안한다. 수치모의 결과 항만유입수로 폭이 축소됨에 따라 부가 Hydrodynamic length에 의해 항만의 고유진동수는 감소하고 따라서 lower bound tunning을 통해 내습하는 파랑의 spectrum의 energy containing part와 유리할 수 있음을 입증하였다.

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Discrete-Time Gaussian Interfere-Relay Channel

  • Moon, Kiryang;Yoo, Do-Sik;Oh, Seong-Jun
    • Journal of Communications and Networks
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    • 제18권3호
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    • pp.299-310
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    • 2016
  • In practical wireless relay communication systems, non-destination nodes are assumed to be idle not receiving signals while the relay sends messages to a particular destination node, which results in reduced bandwidth efficiency. To improve the bandwidth efficiency, we relax the idle assumption of non-destination nodes and assume that non-destination nodes may receive signals from sources. We note that the message relayed to a particular node in such a system gives rise to interference to other nodes. To study such a more general relay system, we consider, in this paper, a relay system in which the relay first listens to the source, then routes the source message to the destination, and finally produces interference to the destination in sending messages for other systems. We obtain capacity upper and lower bounds and study the optimal method to deal with the interference as well as the optimal routing schemes. From analytic results obtained, we find the conditions on which the direct transmission provides higher transmission rate. Next, we find the conditions, by numerical evaluation of the theoretical results, on which it is better for the destination to cancel and decode the interference. Also we find the optimal source power allocation scheme that achieves the lower bound depending on various channel conditions. We believe that the results provided in this paper will provide useful insights to system designers in strategically choosing the optimal routing algorithms depending on the channel conditions.

ART2 알고리즘을 이용한 초음파 영상에서의 충수 추출 (Appendix Extraction from Ultrasound Image using ART2)

  • 김광백
    • 한국정보통신학회논문지
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    • 제19권11호
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    • pp.2540-2545
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    • 2015
  • 본 논문에서는 복부 초음파 영상에서 충수를 추출하는 방법을 제안한다. 제안된 충수 추출 방법은 복부 초음파 영상에서 명암 대비를 강조하기 위해 Ends_in Search Stretching 기법을 적용하고, Max-Min 이진화, 영역 레이블링, 잡음제거, Cubic Spline 보간법을 적용하여 복부 근육의 하단 근막 부분을 추출한다. 그리고 초음파 영상에서 추출된 근막 영역을 제거한 후, ART2 알고리즘을 적용하여 충수를 추출한다. 제안된 방법을 초음파 영상에 적용한 결과, 제안된 충수 추출 방법이 효율적으로 충수가 추출되는 것을 영상의학과 전문의를 통하여 확인하였다.

충전성을 개선한 각형CFT 기둥-보 접합부의 구조 특성 (Structural Characteristic of Beam-to-Column Connections in Rectangular CFT Structures Considering Concrete Filling)

  • 박제영;이명재
    • 한국강구조학회 논문집
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    • 제25권2호
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    • pp.187-196
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    • 2013
  • CFT구조의 기둥-보 접합부는 강관의 국부좌굴을 방지하기위해 다이아프램이 필요하다. 외측다이아프램 형식은 관통다이아프램 형식보다 콘크리트의 충전성이 좋으나 시공성과 건축설비와 공조하는 측면에서 불편함이 있다. CFT구조 접합부의 상부 다이아프램은 외측다이아프램 형식으로 하고 하부 다이아프램은 관통다이아프램 형식으로 하였다. 이것은 건축물에서 바닥슬래브가 있으므로 상부 다이아프램은 바닥슬래브와 일체가 되고 하부 다이아프램으로 관통다이아프램을 적용하여 건축설비와의 마찰을 피하고자 한 것이다. 결과적으로 충전성을 개선시킨 CFT구조의 구조성능은 상, 하부 모두 관통다이아프램을 적용한 구조와 비교하면 동일하다는 것을 알 수 있다.

Secondary Neutron Dose in Carbon-ion Radiotherapy: Investigations in QST-NIRS

  • Yonai, Shunsuke;Matsumoto, Shinnosuke
    • Journal of Radiation Protection and Research
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    • 제46권2호
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    • pp.39-47
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    • 2021
  • Background: The National Institutes for Quantum and Radiological Science and Technology-National Institute of Radiological Sciences (QST-NIRS) has continuously investigated the undesired radiation exposure in ion beam radiotherapy mainly in carbon-ion radiotherapy (CIRT). This review introduces our investigations on the secondary neutron dose in CIRT with the broad and scanning beam methods. Materials and Methods: The neutron ambient dose equivalents in CIRT are evaluated based on rem meter (WENDI-II) measurements. The out-of-field organ doses assuming prostate cancer and pediatric brain tumor treatments are also evaluated through the Monte Carlo simulation. This evaluation of the out-of-field dose includes contributions from secondary neutrons and secondary charged particles. Results and Discussion: The measurements of the neutron ambient dose equivalents at a 90#x00B0; angle to the beam axis in CIRT with the broad beam method show that the neutron dose per treatment dose in CIRT is lower than that in proton radiotherapy (PRT). For the scanning beam with the energy scanning technique, the neutron dose per treatment dose in CIRT is lower than that in PRT. Moreover, the out-of-field organ doses in CIRT decreased with distance to the target and are less than the lower bound in intensity-modulated radiotherapy (IMRT) shown in AAPM TG-158 (American Association of Physicists in Medicine Task Group). Conclusion: The evaluation of the out-of-field doses is important from the viewpoint of secondary cancer risk after radiotherapy. Secondary neutrons are the major source in CIRT, especially in the distant area from the target volume. However, the dose level in CIRT is similar or lower than that in PRT and IMRT, even if the contributions from all radiation species are included in the evaluation.