• 한국컴퓨터정보학회논문지
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• 제20권8호
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• pp.45-52
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• 2015

To solve the problem of low inter-operability of systems and low reusability caused by not being standardized and common-shared development foundation between software developers, the government has proposed e-Government(eGov) standard framework. However, the development method based on eGov standard framework is not easy to learn and to use fluently, because it is so dissimilar the existing traditional development method. In this paper, we propose an approach for developing web applications by reusing common components of eGov standard framework, and describe about the case study of developing Can_Pro(Computer Aided Nutritional analysis program for Professionals) based on eGov standard framework. Consequently, we show improvement in productivity and reduction budget through reusability of common components and eGov standard framework.

• 한국정보전자통신기술학회논문지
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• 제16권5호
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• pp.307-314
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• 2023

슈퍼컴퓨팅 기술 및 하드웨어 기술이 발전함에 따라 기후 예측 모델도 고도화되고 있다. 한국 기상청 역시 영국 기상청으로부터 GloSea5을 도입하였고 한국 기상 환경에 맞추어 업데이트된 GloSea6를 운용 중이다. 각 대학 및 연구기관에서는 슈퍼컴퓨터보다는 사양이 낮은 중소규모 서버에서 활용하기 위해 저해상도 결합모델인 Low-GloSea6를 구축하여 사용하고 있다. 본 논문에서는 중소규모 서버에서의 기상 연구의 효율성을 위한 Low-GloSea6 소프트웨어를 분석하여 가장 많은 CPU Time을 점유하는 대기 모델의 tri_sor.F90 모듈의 tri_sor_dp_dp 서브루틴을 Hotspot으로 검출하였다. 해당 함수에 머신러닝의 한 종류인 선형 회귀 모델을 적용하여 해당 기법의 가능성을 확인한다. 이상치 데이터를 제거 후 선형 회귀 모델을 학습한 결과 RMSE는 2.7665e-08, MAE는 1.4958e-08으로 Lasso 회귀, ElasticNet 회귀보다 더욱 좋은 성능을 보였다. 이는 Low-GloSea6 수행 과정 중 Hotspot으로 검출된 tri_sor.F90 모듈에 머신러닝 기법 적용 가능성을 확인하였다.

• 한국정보전자통신기술학회논문지
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• 제16권6호
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• pp.489-498
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• 2023

하드웨어의 성능 및 컴퓨팅 기술의 발전 덕분에 기후환경 변화를 대비하기 위해 기후예측 모델 또한 발전하고 있다. 한국 기상청은 GloSea6를 도입하여 슈퍼컴퓨터를 이용하여 기상 예측을 하고있으며, 각 대학 및 연구 기관에서는 중소규모 서버에서 사용하기 위해 저해상도 결합모델인 Low-GloSea6를 사용하여 기상 연구에 활용하고 있다. 본 논문에서는 중소규모 서버에서의 기상 연구의 원활한 연구를 위해 Low-GloSea6의 Intel VTune Profiler를 사용한 분석을 진행하였으며 1125.987초의 CPU Time을 수행하는 대기모델의 tri_sor_dp_dp 함수를 Hotspot으로 검출하였다. 수치적 연산을 진행하는 기존 함수에 머신러닝 기법의 하나인 비선형 회귀모델을 적용 및 비교하여 머신러닝 적용 가능성을 확인하였다. 기존 tri_sor_dp_dp 함수의 실제 연산되는 값인 1e-3 ~ 1e-20의 범위를 가지는 Output Data인 변수 "Px"를 기준으로 평가하였을때 K-최근접 이웃 회귀 모델은 MAE가 1.3637e-08, SMAPE가 123.2707%로 가장 우수하게 나타났으며 RMSE의 경우 Light Gradient Boosting Machine 회귀 모델이 2.8453e-08로 가장 우수한 성능을 보이는 것으로 측정되었다. 따라서 Low-GloSea6 수행 과정 중 tri_sor_dp_dp 함수의 데이터를 추출 후 비선형 회귀 모델을 적용한 결과로 기존의 tri_sor_dp_dp 함수의 수치적 연산 값과 K-최근접 이웃 회귀 모델을 비교하였을 때 SMAPE가 123.2707%의 오차가 발생하는 것으로 측정되어 기존 모듈의 대체 가능성이 있다는 것을 확인하였다.

• Journal of Microbiology and Biotechnology
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• 제11권3호
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• pp.524-528
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• 2001

The measurement of radiation response using simple and informative techniques would be of great value in studying the genetic risk following occupational, therapeutic, or accidental exposure to radiation. When patients receive radiation therapy, many suffer from side effects. Since each patient receives a different dose due to different physical conditions, it is important to measure the exact dose of radiation received by each patient to lessen the side effects. Even though several biological dosimetric systems have already been developed, there is no ideal system that can satisfy all the criteria for an idean dosimetric system, especially for low-dose radiation as used in radiation therapy. In this study, an SOS Chromotest of E. coli PQ37 was evaluated as a novel dosimeter for low-dose gamma-rays. E. coli PQ37 was originally developed to screen chemical mutagens using the SOS Chromotest-a colorimtric assay, based on the induction of ${\beta}$-galactosidase ue to DNA damage. The survival fraction of E. coli PQ37 decreased dose-dependently with an increasing dose of cobalt-60 gamma-rays. Also, a good linear correlation was found between the biological damage revealed by the ${\beta}$-galactosidase expression and the doses of gamma-rays. The expression of ${\beta}$-galactosidase activity that responded to low-dose radiation under 1 Gy was $Y=0.404+(0.089{\pm}0.3)D+(-0.018{\pm}0.16)D^2$ (Y, absorbance at 420 nm; D, Dose of irradiation) as calculated using Graph Pad In Plot and Excel. When a rabbit was fed with capsules containing an agar block embdded with E. coli PQ37 showed a linear response to the radiation doses. Accordingly, the results confirm that E. coli PQ37 can be used as a sensitive biological dosimeter fro cobalt-60 gamma-rays. To the best of our knowledge, this is the first time that a bacterium has been used as a biological dosimeter, especially for low-dose radiation.

• 한국수학교육학회지시리즈A:수학교육
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• 제56권2호
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• pp.161-175
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• 2017

The purpose of this study is to compare and analyze the impact on low-achievers in mathematics who studied mathematics using Blended e-learning and Personalized system of instruction after school. Blended e-learning is defined as the management of e-learning using the e-study run by the education office in local. Personalized system of instruction was proceeded as follows; (1) all students are given a syllabicated learning task and a study guide, (2) students study the material autonomously according to their own pace for a certain period of time, (3) the teacher strengthens the students' motivation through grading and feedback after students study a subject and solve the evaluation problem. The learning materials for Personalized system of instruction are re-edited the offline education contents provided by the blended e-learning to the level of students. The 118 $7^{th}$ grade students from the D middle school participated in this study. The results were verified by achievement tests before and after the study, as well as survey regarding their attitude toward mathematics. The results are as follows. First, Blended e-learning has more positive impacts than Personalized system of instruction in mathematics achievement. Second, there was no difference in mathematics achievement according to their self-directed learning between Blended e-learning and Personalized system of instruction. Third, both types utilizing Blended e-learning and Personalized system of instruction have positive effect on attitude toward mathematics, and there is not their difference between two methods of teaching and learning mathematics.

• 약학회지
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• 제48권4호
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• pp.247-253
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• 2004

We investigated the hypoglycemic effect of formula containing Euonymus alatus (EA) and Mori Folium (MF) in multiple low dose (MLD) streptozotocin (STZ)-induced diabetic rats. In order to iduce hyperglycemic state 25 mg/kg of STZ was injected intraperitoneally for 5 consecutive days. SD rats were randomly divided into diabetic control and treatment groups. Treatment groups were administered with either 250 mg/kg of EA and 250 mg/kg of MF (E1Ml), or 500 mg/kg of EA mixed with same dose of MF (E2M2) for 3 weeks. Blood glucose levels and body weights were measured every 5th or 6th day. E1Ml and E2M2 both significantly reduced food intake, water intake, and fasting blood and urine glucose levels as compared to those in diabetic control group in a dose dependent manner. Body weight in diabetic control group was increased slightly after 3 weeks. Treatment group, however, showed gradual increase in body weights during 3 week-period. While plasma insulin levels of the diabetic control group were decreased to the level of 387$\pm$14 pg/ml from 534$\pm$36 pg/ml, those levels in E1Ml and E2M2-treated groups were both markedly increased by 13% and 26%, respectively. Urine glucose levels in E1Ml and E2M2-treated groups were also remarkably reduced by 17 and 26% compared to the levels of diabetic control group. While expression of membrane-bound glucose transporter-4 (GLUT-4) protein in skeletal muscle was reduced by 45% in diabetic control compared to the normal control, GLUT-4 protein expressions in E1Ml and E2M2-treated groups were augmented by 2 and 3.5 times compared to the diabetic control, respectively. Pancreatic HE staining experiments showed that E2M2-treated group revealed much less infiltrated mononuclear cells, indicating that E2M2 efficiently blocked insulitis induced by multiple low dose streptozotocin. Taken together, we conclude that formula containing EA and MF may prevent or delay the development of hyperglycemia through overexpression of GLUT-4 protein in skeletal muscle and prevention of insulitis.

• 한국식품영양학회지
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• 제4권1호
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• pp.21-34
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• 1991

The purposes of this studies were to investigate the effect of dietry Se levels and alcohol administration on the lipid hyperoxidation and the lipid metabolism in the rat. Seventy two male rats of Sprague-Dawley Strain weighting about 58~629 were divided into 12groups. The dietary Se levels were 10, 0.4 and Omg, and the dietary a-tocopherol levels were 150 and 0mg per kg diet, respectively. Alcohol-administrated groups received drinking water solution containing 10% of ethanol from the 3-weeks of experimental periods. The obtained experimental results are summarized as follows. 1. Food intake, body weight gain and food efficiency ratio were significantly lower in H-, L-and alcohol administrated groups(-A) by administrated Se and alcohol in diet. The weight of liver and spleen tended to be greater in H- and alcohol administrated groups. 2. The glutathione values in liver tend to be lower in alcohol or Vit. E administrated groups than nonadministrated groups. Also there were higher in H- and L- than C-groups, but the increasing range decreased due to administrated alcohol. The lipid peroxide values In liver were significantly higher in alcohol groups, and L- and tocopherol groups were higher values. Specially the increasing of lipid peroxide values were significantly effected by alcohol in low Se and Vit. E groups. 3. The contents of total glyceride in plasma were higher in alcohol groups, there were significantly higher values in alcohol administrated groups under low Se and Vit. E groups. The contents of total cholesterol and HDL-cholesterol In plasma were significantly higher in alcohol groups. 4. The contents of total lipid in liver were higher alcohol groups, and slightly higher values in low Se groups(L-groups) than other groups, also higher values in low Vit. E groups. Those of total glyceride in liver were significantly higher in alcohol groups, appeared highest values when alcohol was administrated in low Se and Vit. E groups. The increasing of total glyceride content was significantly effected by alcohol in low Se groups than that in C-groups.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2007년도 추계학술대회 논문집
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• pp.511-511
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• 2007

Low-emissivity (low-e) coatings with visible transparency have attracted increased interest m reducing heat radiation loss through window panes from ecological and sustainable aspects. $TiO_2$-silver transparent thin films for low-e have good properties for UV and IR blocking as well as photocatalyst compared to that with commercial UV blocking films such as fluorine doped oxide (FTO), antimony doped tin oxide (ATO), etc. In this study, transparent $TiO_2$-silver thin films were prepared by successive ink-jet printing of commercial nano silver and $TiO_2$ sol. The $TiO_2$ sol, as ink for ink-jet printing, were synthesized by hydrothermal process in the autoclave externally pressurized with $N_2$ gas of 200 bar at $120^{\circ}C$ for 10 hrs. The synthesized $TiO_2$ sols were all formed with brookite phase and their particle size was several to 30 nm. At first nano sized silver sol was coated on glass substrate, after that $TiO_2$ sol was coated by ink-jet printing. With increasing coating thickness of $TiO_2$-silver multilayer by repeated ink-jet coating, the absorbance of UV region (under 400nm) and IR region (over 700nm) also increase reasonably, compared to that with commercial UV blocking films.

• 한국미생물·생명공학회지
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• 제24권4호
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• pp.393-398
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• 1996

In order to develop a lactic acid bacterial powder which can be used as a probiotic for human and animal, a lactic acid bacteria which has high resistance against low pH and ox-gall, and shows a good growth inhibition against E. coli, was isolated from an animal intestine and characterized. The isolated strain was identified as Enterococcus faecium. It had more than 90% of survival at low pH for 2 hours and almost 100% of survival in the presence of 0.3% ox-gall. When co-cultured with E. coli in MRS broth, all of the E. coli cells were killed within 24 hours. The final powdered product of the isolated strain was manufactured after a freeze drying process using an industrial media, and then checked its stability. Its storage stability was 80% for 11 months at 18$\circ$C.

• 대한전기학회논문지:전력기술부문A
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• 제54권9호
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• pp.434-440
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• 2005

This paper describes an optimized Scheme of reactive-power compensation for the low short-circuit-ratio AC system interconnected with the HVDC system. An HVDC system interconnected with tile low SCR AC system is vulnerable to the ac voltage variation, which brings about the commutation failure of the converter. This problem can be solved using optimized compensation of reactive power. In this study, a benchmark system for HVDC system interconnected with low SCR AC system is derived using PSS/E simulation. Then an optimized srheme for reactive power compensation was derived using integer programming. The feasibility of proposed scheme was analyzed through silnulations with PSS/E and PSCAD/EMTDC. The proposed scheme can compensate the reactive power accurately and minimize the number of switching for harmonic filters and shunt reactors.