• Title/Summary/Keyword: Low level radiation

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Epidemiology of Low-Dose Ionizing Radiation Exposure and Health Effects (저선량 방사선 노출과 건강 영향에 대한 역학적 고찰)

  • Won Jin Lee
    • Journal of Environmental Health Sciences
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    • v.49 no.1
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    • pp.1-10
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    • 2023
  • Low-dose radiation exposure has received considerable attention because it reflects the general public's type and level of exposure. Still, controversy remains due to the relatively unclear results and uncertainty in risk estimation compared to high-dose radiation. However, recent epidemiological studies report direct evidence of health effects for various types of low-dose radiation exposure. In particular, international nuclear workers' studies, CT exposure studies, and children's cancer studies on natural radiation showed significantly increased cancer risk among the study populations despite their low-dose radiation exposure. These studies showed similar results even when the cumulative radiation dose was limited to an exposure group of less than 100 mGy, demonstrating that the observed excess risk was not affected by high exposure. A linear dose-response relationship between radiation exposure and cancer incidence has been observed, even at the low-dose interval. These recent epidemiological studies include relatively large populations, and findings are broadly consistent with previous studies on Japanese atomic bomb survivors. However, the health effects of low-dose radiation are assumed to be small compared to the risks that may arise from other lifestyle factors; therefore, the benefits of radiation use should be considered at the individual level through a balanced interpretation. Further low-dose radiation studies are essential to accurately determining the benefits and risks of radiation.

Tissue distribution, excretion and effects on genotoxicity of tritium following oral administration to rats

  • Lee, Jei Ha;Kim, Cha Soon;Choi, Soo Im;Kim, Rae-Kwon;Kim, Ji Young;Nam, Seon Young;Jin, Young Woo;Kim, In Gyu
    • Nuclear Engineering and Technology
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    • v.51 no.1
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    • pp.303-309
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    • 2019
  • Tritium is an important nuclide that must be monitored for radiation safety management. In this study, HTO was orally administered to rats at the level of 37 kBq ($1{\mu}Ci$) or 370 kBq ($10{\mu}Ci$) to examine tissue distribution and excretion levels. After sacrifice, wet and dry tissue samples were weighed and analyzed for tissue free-water tritium (TFWT) and organically bound tritium (OBT). The mean tissue concentrations of TFWT (OBT) were 30.9 (17.8) and 4.4 (8.1) Bq/g on days 7 and 13 at the 37 kBq level and 30.8 (64.6) Bq/g on day 17 at the 370 kBq level. To assess the cytogenetic damage due to tritium exposure, a cytokinesis-blocked micronucleus (MN) assay was performed in blood samples from rats exposed to HTO for 14 and 21 days after oral administration. There was no significant difference in the MN frequencies between the control and exposed rats.

Analysis of University Student Awareness of Radiation Exposures from Consumer Products

  • Kim, SeungHwan;Cho, Kunwoo
    • Journal of Radiation Protection and Research
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    • v.41 no.1
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    • pp.57-70
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    • 2016
  • Background: Since the terminology 'radioactive consumer product' is not quite familiar to the public and is often considered as negative and detrimental things, the educational curriculum is essential for establishing reliability of nuclear energy related and for the development of better communication strategy of radiation risk with the public. To provide base data which is valuable for establishing efficient curriculum of education and training about radiation safety, it is necessary to apprehend the different level of awareness of radiation exposures classified by various consumer products. Materials and Methods: On November 2014, a question investigation about asking awareness level of radiation exposure from various consumer products was done for university students who are highly educated. The object students are studied at a four-year-course universities which is located at Daejeon City. Results and Discussion: Although the average awareness level is comparatively low, the awareness of senior students, who major in radiation, nuclear related departments and male students are relatively high. On the other hand, the awareness of freshman, sophomore, junior students, who do not major in radiation, nuclear related departments and female students are relatively low. It is necessary to provide various information to avoid unnecessary concerns and misconceptions about radiation exposure. Conclusion: This paper will be an instrument for efficient establishment of curriculum of education and training related with radiation safety.

A STUDY OF THE LOW LEVEL RADIATION EFFECT ON THE MITOTIC INDEX OF THE BASAL CELLS IN THE BUCCAL POUCH OF HAMSTERS (저선량방사선이 햄스터의 협낭 기저세포 분열지수에 미치는 영향에 관한 연구)

  • Kang Byung-Cheol;You Dong-Soo
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.23 no.2
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    • pp.215-226
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    • 1993
  • The purpose of this study was to investigate the effects of the low level irradiation on the mitotic index of the basal cells in the buccal pouch of hamsters{golden hamster: APG strain). After colchicine was administrated to the hamsters through the intraperitoneal, the low level radiation{5460mR) was exposed on the buccal pouch of hamsters. The mitotic index of the basal cells was estimated 2 hours after irradiation. The results were as follows: 1. The mean mitotic index of the control group was 4.32. 2. The mean mitotic index of the irradiated group was 2.46. 3. T-test of data in the irradiated group showed significant difference from the mitotic index in the control group. These results suggested the lowered mitotic index of the irradiated group resulted from the low level irradiation.

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Low-dose Radiation Induces Antitumor Effects and Erythrocyte System Hormesis

  • Yu, Hong-Sheng;Liu, Zi-Min;Yu, Xiao-Yun;Song, Ai-Qin;Liu, Ning;Wang, Hao
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.7
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    • pp.4121-4126
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    • 2013
  • Objective: Low dose radiation may stimulate the growth and development of animals, increase life span, enhance fertility, and downgrade the incidence of tumor occurrence.The aim of this study was to investigate the antitumor effect and hormesis in an erythrocyte system induced by low-dose radiation. Methods: Kunming strain male mice were subcutaneously implanted with S180 sarcoma cells in the right inguen as an experimental in situ animal model. Six hours before implantation, the mice were given 75mGy whole body X-ray radiation. Tumor growth was observed 5 days later, and the tumor volume was calculated every other day. Fifteen days later, all mice were killed to measure the tumor weight, and to observe necrotic areas and tumor-infiltration-lymphoreticular cells (TILs). At the same time, erythrocyte immune function and the level of 2,3-diphosphoglyceric acid (2,3-DPG) were determined. Immunohistochemical staining was used to detect the expression of EPO and VEGFR of tumor tissues. Results: The mice pre-exposed to low dose radiation had a lower tumor formation rate than those without low dose radiation (P < 0.05). The tumor growth slowed down significantly in mice pre-exposed to low dose radiation; the average tumor weight in mice pre-exposed to low dose radiation was lighter too (P < 0.05). The tumor necrosis areas were larger and TILs were more in the radiation group than those of the group without radiation. The erythrocyte immune function, the level of 2,3-DPG in the low dose radiation group were higher than those of the group without radiation (P < 0.05). After irradiation the expression of EPO of tumor tissues in LDR group decreased with time. LDR-24h, LDR-48h and LDR-72h groups were all statistically significantly different from sham-irradiation group. The expression of VEGFR also decreased, and LDR-24h group was the lowest (P < 0.05). Conclusion: Low dose radiation could markedly increase the anti-tumor ability of the organism and improve the erythrocyte immune function and the ability of carrying $O_2$. Low-dose total body irradiation, within a certain period of time, can decrease the expression of hypoxia factor EPO and VEGFR, which may improve the situation of tumor hypoxia and radiosensitivity of tumor itself.

Tritium( $^3$H) Activity Measurement by the Liquid Scintillation Counting Method

  • Hwang, Sun-Tae;Oh, Pil-Jae;Lee, Min-Kie;Kim, Wi-Soo
    • Journal of Korean Society for Atmospheric Environment
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    • v.10 no.E
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    • pp.299-302
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    • 1994
  • At a nuclear power plant, environmental radioactivity monitoring is routine work for the radiation safety management For the environmental monitoring of tritium($^3$H) activity in water sampled liquid scintillation counting( LSC) method is applied to measure low- energy beta activity from tritium in the samples. The $^3$H activity is measured using the BECKMAN 5801 system at the KRISS( Korea Research Institute of Standards and Science) for evaluating the lower limits of detection( LLD) of $^3$H measurement and the measuring capability of low-level $^3$H activity at four nuclear Power Plant sites. The LSC systems used for low-level $^3$H activity measurements at the nuclear Power Plants are confirmed to satisfy throughout an intercomparison study under the experimental arrangements by the KRISS.

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Preliminary Radiation Exposure Dose Evaluation for Workers of the Landfill Disposal Facility Considering the Radiological Characteristics of Very Low Level Concrete and Metal Decommissioning Wastes (극저준위 콘크리트, 금속 해체방폐물의 방사선적 특성을 고려한 매립형 처분시설 방사선작업자 예비 피폭선량 평가)

  • Ho-Seog Dho;Ye-Seul Cho;Hyun-Goo Kang;Jae-Chul Ha
    • Journal of Radiation Industry
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    • v.17 no.4
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    • pp.509-518
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    • 2023
  • The Kori Unit 1 nuclear power plant, which is planned to be dismantled after permanent shutdown, is expected to generate a large amount of various types of radioactive waste during the dismantling process. For the disposal of Very-low-level waste, which is expected to account for the largest amount of generation, the Korea Radioactive waste Agency (KORAD) is in the process of detailed design to build a 3-phase landfill disposal facility in Gyeongju. In addition, a large container is being developed to efficiently dispose of metal and concrete waste, which are mainly generated as Very low-level waste of decommissioning. In this study, based on the design characteristics of the 3-phase landfill disposal facility and the large container under development, radiation exposure dose evaluation was performed considering the normal and accident scenarios of radiation workers during operation. The direct exposure dose evaluation of workers during normal operation was performed using the MCNP computer program, and the internal and external exposure dose evaluation due to damage to the decommissioning waste package during a drop accident was performed based on the evaluation method of ICRP. For the assumed scenario, the exposure dose of worker was calculated to determine whether the exposure dose standards in the domestic nuclear safety act were satisfied. As a result of the evaluation, it was confirmed that the result was quite low, and the result that satisfied the standard limit was confirmed, and the radiational disposal suitability for the 3-phase landfill disposal facility of the large container for dismantled radioactive waste, which is currently under development, was confirmed.

A Study On Low Radiation Measurement of Radiation Measuring Devices and Improvement of Reaction Speed according to the Rapid Change of Radiation Dose (방사선 측정장치의 저준위 방사선 측정과 방사선량의 급격한 변화에 따른 장치의 반응 속도개선에 관한 연구)

  • Lee, Joo-Hyun;Lee, Seung-Ho
    • Journal of IKEEE
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    • v.18 no.4
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    • pp.544-551
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    • 2014
  • This paper suggests an algorithm to measure low-level radiation by radiation measuring devices, and the other algorithm to improve reaction speed of the device to better respond to dramatic changes in radiation amount. The former algorithm to improve the accuracy of measuring low-level radiation takes advantage of a dual window radiation measurement method which is based on accumulated average of pulses gathered by a radiation measuring sensor. The latter algorithm is to enhance reaction speed of a measuring device to more sensitively react to dramatic changes in radiation amount by adopting a dual window radiation measurement method which analyzes data patterns newly put into for six seconds. To verify the suggested algorithms, a hardware-which consists of sensor and high-voltage generator, controller, charger and power supply circuit, wireless communication part, and display part-was used. Tests conducted on the dual window radiation measurement method as used in the suggested algorithm have proved that accuracy improves to measure low-level radiation of 5uSv/h, and linearity also gets better. Other tests were conducted to see whether the suggested algorithm enhances the reaction speed of a radiation measuring device so that the device responds better to dramatically changing radiation amount. The experimental results have shown meaningful changes in numbers after six seconds. Therefore, the conclusions are made that the algorithm enhances the reaction speed of the device.

DOSE AND DOSE RATE EFFECTS OF IRRADIATION ON BLOOD COUNT AND CYTOKINE LEVEL IN BALB/c MICE

  • Son, Yeonghoon;Jung, Dong Hyuk;Kim, Sung Dae;Lee, Chang Geun;Yang, Kwangmo;Kim, Joong Sun
    • Journal of Radiation Protection and Research
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    • v.38 no.4
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    • pp.179-184
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    • 2013
  • The biological effects of radiation are dependent on the dose rate and dose of radiation. In this study, effects of dose and dose rate using whole body radiation on plasma cytokines and blood count from male BALB/c mice were evaluated. We examined the blood and cytokine changes in mice exposed to a low (3.49m Gy $h^{-1}$) and high (2.6 Gy $min^{-1}$) dose rate of radiation at a total dose of 0.5 and 2 Gy, respectively. Blood from mice exposed to radiation were evaluated using cytokine assays and complete blood count. Peripheral lymphocytes and neutrophils decreased in a dose dependent manner following high dose rate radiation. The peripheral lymphocytes population remained unchanged following low dose rate radiation; however, the neutrophils population increased after radiation. The sera from these mice exhibited elevated levels of flt3 ligand and granulocyte-colony-stimulating factor (G-CSF), after high/low dose rate radiation. These results suggest that low-dose-rate radiation does not induce blood damage, which was unlike high-dose-rate radiation treatment; low-dose-rate radiation exposure activated the hematopoiesis through the increase of flt3 ligand and G-CSF.

The research of the UWB system radiation measurement (UWB 시스템의 방사출력 측정방법 연구)

  • Song, Hong-Jong;Cha, Jae-Sang
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.10 no.5
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    • pp.277-286
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    • 2010
  • In this paper we analyse radiation measurement method for UWB wireless system of the wideband low power frequency characteristics. In the radiation measurement environment we discuss RMS electric field strength, UWB PSD, UWB detect signal level, UWB noise signal collection etc.. also, we discuss power measure method of the CISPR16-1, low level e.i.r.p radiation measurement method. lastly we analyse consideration problem for the signal analyser of the UWB system.