• Title/Summary/Keyword: Low dose radiation

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Dosimetric Evaluation of Low-Dose Spillage Volumes for Head and Neck Cancer Using Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy Treatment Techniques

  • Kumar, Gourav;Bhushan, Manindra;Kumar, Lalit;Kishore, Vimal;Raman, Kothanda;Kumar, Pawan;Barik, Soumitra;Purohit, Sandeep
    • Progress in Medical Physics
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    • v.32 no.3
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    • pp.70-81
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    • 2021
  • Purpose: This study was designed to investigate the dosimetric difference between intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) in head and neck cancer (HNC). The study primarily focuses on low-dose spillage evaluation between these two techniques. Methods: This retrospective study involved 45 patients with HNC. The treatment plans were generated using the IMRT and VMAT techniques for all patients. Dosimetric comparisons were performed in terms of target coverage, organ-at-risk (OAR) sparing, and various parameters, including conformity index, uniformity index, homogeneity index, conformation number, low-dose volumes, and normal tissue integral dose (NTID). Results: No significant (P>0.05) difference in planning target volume coverage (D95%) was observed between IMRT and VMAT plans for supraglottic larynx, hard palate, and tongue cancers. A decrease in dose volumes ranging from 1 Gy to 30 Gy was observed for VMAT plans compared with those for IMRT plans, except for V1Gy and V30Gy for supraglottic larynx cancer and V1Gy for tongue cancer. Moreover, decreases (P<0.05) in NTID were observed for VMAT plans compared with that for IMRT plans in supraglottic larynx (4.50%), hard palate (12.80%), and tongue (7.76%) cancers. In contrast, a slight increase in monitor units for VMAT compared with those for IMRT in supraglottic larynx (0.46%), hard palate (2.54%), and tongue (7.56%) cancers. Conclusions: For advanced-stage HNC, both IMRT and VMAT offer satisfactory clinical plans. VMAT offers a conformal and homogeneous dose distribution with comparable OAR sparing and higher dose falloff outside the target volume than IMRT, which provides an edge to reduce the risk of secondary malignancies for HNC over IMRT.

Determination of Environmental Radiation Dose Rate in the Southeastern Korea (우리나라 남동지방(南東地方)의 환경방사선(環境放射線) 선량율(線量率)의 결정(決定)(1980년도(年度)))

  • Rho, Chae-Shik;Lee, Hyun-Duk
    • Journal of Radiation Protection and Research
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    • v.5 no.1
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    • pp.1-6
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    • 1980
  • A portable count-ratemeter and a thermoluminescent detector ($CaSO_4:Dy$) have been used to obtain total gamma dose rates at approximately 50 locations during the course of several survey trips in the southeastern Korea. The purposes of these measurement were to provide a future reference data and to establish the approximate range of population exposure to the natural environmental radiation. The natural levels encountered ranged from a low of 14.6 microroentgen per hour to a high of 18.9 microroentgen per hour with a mean of $16.3{\pm}1.0$ microroentgen per hour. Among these results are the relatively high natural dose rate levels in the Masan area and Yangsan-Tongdosa area with the relatively low natural dose rate levels in the Gyeongsan-Cheongdo area and the Samrangjin-Jinyeong-Gimhae area.

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Cytokinesis-blocked micronuclei in the human peripheral lymphocytes following low dose γ-rays irradiation (저선량의 감마선 피폭된 사람 말초 임파구의 미소핵을 이용한 방사선 생물학적 피폭선량 측정법 연구)

  • Kim, Tae-hwan
    • Korean Journal of Veterinary Research
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    • v.41 no.1
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    • pp.99-104
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    • 2001
  • To determine if micronucleus (MN) assay could be used to predict the absorbed dose of victims after accidental radiation exposure, we carried out to assess the absorbed dose depending on the numerical changes of MN in human peripheral blood lymphocytes after $^{60}Co\;{\gamma}-rays$ exposure in the range of 0.25 to 1 Gy, respectively. The MNs were observed at very low doses, and the numerical changes according to doses. Satisfactory dose-effect calibration curve is observed after low dose irradiation of human lymphocytes in vitro. When plotting on a linear scale against radiation dose, the line of best fit was $Y=(0.02{\pm}0.0009)+(0.033{\pm}0.010)D+(0.012{\pm}0.012)D^2$. The dose-response curve for MN induction immediately after irradiation was linear-quadratic and has a significant relationship between the frequencies of MN and dose. These data show a trend towards increase of the numbers of MN with increasing dose. The number of MN in lymphocytes that were observed in the control group is $0.1610{\pm}0.0093/cell$. Accordingly, MN assay in human peripheral lymphocytes could be a useful in viva model for studying radio-protective drug sensitivity or screening test, microdosimertic indicator and radiation-induced target organ injury. Since MN assay is simple, rapid and reproducible, it will also be a biodosimetric indicator for individual dose assessment after accidental exposure.

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Dosimetric comparison of coplanar and non-coplanar volumetric-modulated arc therapy in head and neck cancer treated with radiotherapy

  • Gayen, Sanjib;Kombathula, Sri Harsha;Manna, Sumanta;Varshney, Sonal;Pareek, Puneet
    • Radiation Oncology Journal
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    • v.38 no.2
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    • pp.138-147
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    • 2020
  • Purpose: To evaluate the dosimetric variations in patients of head and neck cancer treated with definitive or adjuvant radiotherapy using optimized non-coplanar (ncVMAT) beams with coplanar (cVMAT) beams using volumetric arc therapy. Materials and Methods: Twenty-two patients of head and neck cancer that had received radiotherapy using VMAT in our department were retrospectively analyzed. Each of the patients was planned using coplanar and non-coplanar orientations using an optimized couch angle and fluences. We analyzed the Conformity Index (CIRTOG), Dose Homogeneity Index (DHI), Heterogeneity Index (HIRTOG), low dose volume, target and organs-at-risk coverage in both the plans without changing planning optimization parameters. Results: The prescription dose ranged from 60 Gy to 70 Gy. Using ncVMAT, CIRTOG, DHI and HIRTOG, and tumor coverage (ID95%) had improved, low dose spillage volume in the body V5Gy was increased and V10Gy was reduced. Integral dose and intensity-modulated radiation therapy factor had increased in ncVMAT. In the case of non-coplanar beam arrangements, maximum dose (Dmax) of right and left humeral head were reduced significantly whereas apex of the right and left lung mean dose were increased. Conclusion: The use of ncVMAT produced better target coverage and sparing of the shoulder and soft tissue of the neck as well as the critical organ compared with the cVMAT in patients of head and neck malignancy.

A Study on the Reduction of Cosmic Radiation Exposure by Flight Crew (항공승무원의 우주방사선 피폭 저감에 관한 연구)

  • Ahn, Hee-Bok;Kim, Kyu-Wang;Choi, Youn-Chul
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.28 no.1
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    • pp.1-6
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    • 2020
  • The purpose of this study is to analyze the radiation dose data of the space crew of the flight crew and to present a plan for the health management of the flight crew on the basis of the analysis. The analysis show that the average exposure dose of the flight attendants continued to rise, and the exposure dose of the flight attendants was five(5) times higher than that of the radiation workers. As a way to reduce the effects of cosmic radiation, this paper suggests appropriate personnel allocation by model, balanced allocation of high and low latitude routes by crew according to the aircraft type, and a low altitude flight plan for high latitude flight. This study will help aviation crew members understand cosmic radiation and trust in the company's policies. In the future, it will be necessary to enhance the flight safety of the crew by deriving meaningful results by analyzing data related to cosmic radiation of various routes.

Radiation Dose and Image Quality of Low-dose Protocol in Chest CT: Comparison of Standard-dose Protocol (흉부 CT촬영에서 저선량 프로토콜의 선량과 화질: 표준선량 프로토콜과 비교)

  • Lee, Won-Jeong;Ahn, Bong-Seon;Park, Young-Sun
    • Journal of Radiation Protection and Research
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    • v.37 no.2
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    • pp.84-89
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    • 2012
  • The purpose of this study was to compare radiation dose and image quality between low-dose (LDP) and standard-dose protocol (SDP). LDP (120 kVp, 30 mAs, 2-mm thickness) and SDP (120 kVp, 180 mAs, 1.2-mm thickness) images obtained from 61 subjects were retrospectively evaluated at level of carina bifurcation, using multi-detector CT (Brilliance 16, Philips Medical Systems). Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated at ascending aorta and infraspinatus muscle, from CT number and back-ground noise. Radiation dose from two protocols measured at 5-point using acrylic-phantom, and CT number and noise measured at 4-point using water-phantom. All statistical analysis were performed using SPSS 19.0 program. LDP images showed significantly more noise and a significantly lower SNR and CNR than did SDP images at ascending aorta and infraspinatus muscle. Noise, SNR and CNR were significantly correlated with body mass index (p<0.001). Radiation dose, SNR and CNR from phantom were significant differences between two protocols. LDP showed a significant reduction of radiation dose with a significant change in SNR and CNR compared with SDP. Therefore, exposure dose on LDP in clinical applications needs resetting highly more considering image quality.

Implementation of Electronic Personal Dosimeter Using Silicon PIN Photodiode (실리콘 핀 포토다이오드를 이용한 능동형 방사선 피폭 전자선량계의 구현)

  • 이운근;백광렬;권석근
    • Journal of Institute of Control, Robotics and Systems
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    • v.9 no.4
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    • pp.296-303
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    • 2003
  • A personal portable type electronic dosimeter using silicon PIN photodiode and small GM tube is recently attracting much attention due to its advantages such as an immediate indication function of dose and dose rate, alerting function, and efficient management of radiation exposure history and dose data. We designed and manufactured a semiconductor radiation detector aimed to directly measure X-ray and v-ray irradiated in silicon PIN photodiode, without using high-priced scintillation materials. Using this semiconductor radiation detector, we developed an active electronic dosimeter, which measures the exposure dose using pulse counting method. In this case, it has a shortcoming of over-evaluating the dose that shows the difference between the dose measured with electronic dosimeter and the dose exposed to the human body in a low energy area. We proposed an energy compensation filter and developed a dose conversion algorithm to make both doses indicated on the detector and exposed to the human body proportional to each other, thus enabling a high-precision dose measurement. In order to prove its reliability in conducting personal dose measurement, crucial for protecting against radiation, the implemented electronic dosimeter was evaluated to successfully meet the IEC's criteria, as the KAERI (Korea Atomic Energy Research Institute) conducted test on dose indication accuracy, and linearity, energy and angular dependences.

Radiation Safety Exploration Using Radio-photoluminescence Dosimeter for Crookes Tubes in Junior and Senior High School in Japan

  • Akiyoshi, Masafumi;Do, Duy Khiem;Yamaguchi, Ichiro;Kakefu, Tomohisa;Miyakawa, Toshiharu
    • Journal of Radiation Protection and Research
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    • v.46 no.3
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    • pp.106-111
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    • 2021
  • Background: Crookes tube is utilized in junior high and high schools in Japan to study the character of electrons and current, and not for radiological education. There is no official guideline or regulation for these radiation source to the public. Therefore, most teachers have no information about the leakage of X-rays from Crookes tube. The peak energy of X-rays is approximately 20 keV, and it is impossible to measure using conventional survey meters. Materials and Methods: Each leakage dose of low energy X-rays from 38 Crookes tube in the education field, such as junior and senior high schools in Japan, was explored by the teachers in the school using radio-photoluminescence (RPL) dosimeters. Before and after the measurements, the dosimeters were sent by postal mails. Results and Discussion: At the exploration in this study, it was estimated that the 70 ㎛ dose equivalent, Hp(0.07) of X-rays from 31 Crookes tubes were smaller than 100 µSv in 10 minutes, at the distance of 1 m, where the Crookes tube was usually observed. However, the highest dose was estimated as 0.69 mSv by an equipment with the full power. Furthermore, one Crookes tube exhibited 0.62 mSv with minimum output power of the induction coil. This relatively large dose was reduced by the shorter distance of discharge electrodes of the induction coil. Conclusion: The leakage dose of low energy X-rays from 38 Crookes tube was explored using RPL dosimeters. It was estimated that the Hp(0.07) of X-rays from 31 Crookes tubes were smaller than 100 µSv in 10 minutes at the distance of 1 m, while some equipment radiated a higher dose. With this study, the provisional guideline for the safety operation of Crookes tube is established.