• Title/Summary/Keyword: Low density lipoprotein-cholesterol

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The Change of The Effect on The Subcutaneous Fat Area and Visceral Fat Area by The Functional Electrical Stimulation and Aerobic Exercise (기능적 전기 자극과 유산소 운동이 복부비만의 피하지방과 내장지방에 미치는 효과)

  • Oh Sung-tae;Lee Mun-hwan;Park Rae-Joon
    • The Journal of Korean Physical Therapy
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    • v.16 no.1
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    • pp.85-123
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    • 2004
  • Back ground : Subcutaneous fat area is the main factor involved in replacement disease and arteriosclerosis. Simple weight control is the appropriate medical treatment. It's understood that weight reduction does not only reduce the fat concentrations in blood but also reduces blood pressure, improves glucose levels in diabetes patients and reduces incidents of heart disease. there are several methods for reducing fat in the abdominal region but their effectiveness is not folly understood. one method is electrical stimulation of the problem areas. Method : From May 1st 2002 to October 31st. The 15 subjects who received medical examination were aged between 25 and 53 and were of mixed gender. The subjects were divided into two groups one to received functional electrical stimulation and the other a control group. Using Broca's criterion for judging fat grades. I analysed the differences between the two groups before and after the treatment. Subjects received functional electrical stimulation on the abdominal muscle intensity 50Hz. They received this treatment 4 days a week for 40 minutes a day. In the case of aerobic exercise, at the Treadmill, we used it with the intensity of $75\%$ maximum heart rate (220-age). Result 1)After functional electrical stimulation in the case of male subjects, the weight was reduced 1.93kg, obesity $2.60\%$, fat mass 2.73kg, Percent body fat $4.40\%$, waist circumference 6.53cm, circumference of hips 5.53cm. On the other side, the quality of muscle was increased at the rate of 1.03kg, but it's not attentional level. The subcutaneous fat area was reduced by $26.63cm^2$, the visceral fat area was reduced by $43.00cm^2$, In the female subjects, we can see the reduction of fat grade by $26.63cm^2$, the quantity of body fat by 1.5kg, percent body fat by $1.77\%$, circumference of waist by 4.02cm, circumference of hips by 3.67cm, weight by 1.40kg but was increased 0.72kg at the quantity of muscles. We can see the reduction also in the subcutaneous fat area $24.03cm^2$, the visceral fat area by $25.36cm^2$. 2)After aerobic exercise, on the male subjects, we can see reduction of weight by 3.36kg, obesity by $4.00\%$, fat mass by 2.83kg and we can see increase at the soft lean mass by 2.96kg, but we can see reduction, the percent body fat by $3.03\%$, fat distribution by $0.023\%$, circumference of waist by 3.10cm, circumference of hips by 2.23cm. The female subjects show a reduction in the weight by 2.48kg, percent body fat by $2.20\%$, show an increase in the soft lean mass by 1.54kg. We can see a reduction in the quantity of fat mass by 2.32kg, the percent body fat by $2.80\%$, the circumference of waist by 2.16cm, the circumference of hips by 2.68cm, the fat distribution by $0.016\%$, the subcutaneous fat area by $15.25cm^2$ the visceral fat area by $11.52cm^2$. After aerobic exercise, we can't see the attentional change at the total cholesterol, triglyceride, high density lipoprotein cholesterol, low density lipoprotein cholesterol. 3)After the application of functional electrical stimulation and aerobic exercise, in result of measurement on the body ingredient, we could see the weight reduction and increase the quantity of muscle with the male group who exercised aerobic. We can see the attentional rate on the electrical stimulation about abdominal fat rate, circumference of waist, circumference of hips. The other hand, I couldn't see the attentional differences between the two groups in the rate of fatness and quantity of body fat and the rate of body fat. There isn't any attentional difference in the area of fat under skin, on the contrary, There is attentional difference in the fat in the internal organs area at the electrical stimulation site. We can't see the attentional change of total cholesterol, triglyceride, high density lipoprotein cholesterol, low density lipoprotein cholesterol between electrical stimulation and aerobic exercise. 4)After execution of functional electrical stimulation and aerobic exercise, in result of measurement on change of body ingredient among female objects, We could see weight reduction, increase at muscle quantity in the aerobic exercise group. We could see the attentional differences in the rate of fatness, the rate of abdominal region, the circumference which received electrical stimulation. But, we couldn't see the attentional differences between two groups in the quantity of body fatness, the circumference of hips. The subcutaneous fat area doesn't show the attentional differences. On the Contrary, we could see lots of differences in the visceral fat area of the electrical stimulation group. Conclusion The results show that functional electrical stimulation and aerobic exercise have insignificant differences when if comes to total cholesterol, triglyceride, high density lipoprotein cholesterol, low density lipoprotein cholesterol. Though there is affirmative change in body ingredient after both electrical stimulation and aerobic exercise. Functional electrical stimulation is more effective on the subcutaneous fat area and in changing visceral fat area. There fore. It is concluded that the physical therapy is more effective in the treatment of abdominal fatness.

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Cholesterol-lowering Efficacy of Unrefined Bran Oil from the Pigmented Black Rice (Oryza sativa L cv. Suwon 415) in Hypercholesterolemic Rats

  • Nam, Yean-Ju;Nam, Seok-Hyun;Kang, Mi-Young
    • Food Science and Biotechnology
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    • v.17 no.3
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    • pp.457-463
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    • 2008
  • The effects of dietary supplementation of the unrefined rice bran oil from 'Suwon 415' pigmented black rice (BRBO) on cholesterol metabolism and cellular antioxidant status were investigated in hypercholesterolemic rats. The significant reduction of total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) concentrations was observed in the plasma of rats fed BRBO. BRBO also decreased plasma and hepatic oxidative stress as a result of increased levels of hepatic thiobarbituric acid reactive substances (TBARS) levels associated with the elevations of hepatic superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities together with increased plasma level of tocopherol. This study indicates that dietary BRBO supplement can leads to the improvement of overall cholesterol metabolism and antioxidant status even more effectively than 'Chuchung' white rice (WRBO). Consumption of BRBO may also protect the liver from oxidative damage caused by lipid peroxidation.

The Effects of Weight Control Program on Body Composition, Blood Pressure, Serum Lipid and Self-Regulation Behavior in Obese College Women (비만중재프로그램이 비만 여대생의 신체구성, 혈압, 혈중지질 및 자기조절행위에 미치는 효과)

  • Kim, Kyung Hae;Chung, Bok Yae;Byun, Hye Sun
    • Korean Journal of Adult Nursing
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    • v.19 no.3
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    • pp.339-352
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    • 2007
  • Purpose: The purpose of this study was to investigate the effect of weight control program on body composition(body mass index and waist-hip ratio), blood pressure, serum lipids(total cholesterol, triglyceride, high density lipoprotein and low density lipoprotein) and self-regulation behavior in obese college women. Methods: Forty seven obese subjects were divided into experimental(22) and control(25) groups. The weight control program lasting 12 weeks consisted of a traffic-light diet, jumping-rope exercises, and behavior modification methods with e-mail counseling. The data were collected from 29 March to 17 September of 2004. The variables were assessed before and after intervention for 12 weeks in two groups. Then, those were repeated after a 12 week suspension of intervention in the experimental group. The data were analysed by the SPSS computer program. Results: BMI, HDL, LDL and self-regulation behavior levels showed significant differences between the experimental and control groups. While there were no significant differences in waist-hip ratio, blood pressure, total cholesterol and triglyceride. Conclusion: The weight control program had a positive effect on obese college women, and can be used to control obesity.

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Comparison of Obesity Management Between a Behavior Modification Program and an Aerobic Exercise Program in Overweight Adolescent Girls (행동수정프로그램과 에어로빅 운동의 과체중 여자 중학생 비만관리 효과 비교)

  • 문정순;정승교
    • Journal of Korean Academy of Nursing
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    • v.26 no.4
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    • pp.799-807
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    • 1996
  • This study was done to compare the effects of managing obesity using a behavior modification program and an aerobic exercise in adolescent girls. Thirty three subjects were selected from one girls' middle school located in Seoul. Seventeen girls participated in the behavior modification program by joining 60-90 minute group sessions weekly. The aerobic exercise program was given to 16 girls three times per week for 60 minutes each. These iterventions continued for eight weeks from October 17 to December 10, 1995. The data were obtained before and after the interventions by measuring degree of obesity, body weight, blood pressure, serum lipid, %body fat, and waist to hip ratio(WHR). Data ware analysed by using paired t-test. The results are as follows. 1. Subjects in both the behavior modification and the aerobic exercise groups showed significant decrese in the degree of obesity, body weight, diastolic blood pressure, total cholesterol, low density lipoprotein, %body fat and fat mass after the 8-week interventions. 2. Systolic bood pressure, high density lipoprotein cholesterol and waist to hip ratio were significantly decreased after the 8-week intervention in the behavior modification program group while triglyceride was significantly decreased after the 8-week intervention in the aerobic exercise program group. These findings indicate that both behavior modification and aerobic exercise programs are good strategies for managing obesity among adolescent girls.

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Hepatoprotective Effects of the Water Extract of Protaetia brevitarsis Larva Against Carbon Tetrachloride-Induced Liver Injury in Rats (사염화탄소에 의해 유도된 흰쥐의 간장해에 미치는 지잠의 보호효과)

  • Yun, Soo-Hong;Kim, Duk-Hyun;Lee, Sang-Kyu;Kim, Ju-Hyun;Seo, Young-Min;Kang, Mi-Jeong;Jeon, Tae-Won;Jeon, Tae-Cheon
    • YAKHAK HOEJI
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    • v.51 no.4
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    • pp.277-284
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    • 2007
  • Hepatoprotective effects of the water extract of Protaetia brevitarsis larva (PB) was investigated in carbon tetrachloride ($CCI_{4}$) treated male Sprague-Dawley rats. PB administration protected rats against ALT, AST and LDH elevations induced by $CCI_{4}$, as well as the severity of liver damage. PB recovered the decrease in serum level of high-density lipoprotein-cholesterol and the increase in serum level of low-density lipoprotein-cholesterol induced by $CCI_{4}$. In histopathological observation, massive fatty change and necrosis in the centrilobular area, degenerative change including pyknosis of nucleus and swelling of parenchymal cell induced by $CCI_{4}$ were clearly protected by PB. These histopathological findings paralleled with the serum biochemical results. The present results demonstrated that the water extract of PB may have the hepatoprotective effect against $CCI_{4}$-induced liver damage in vivo.

Bioactivities of Fermented Rhynchosia nulubilis in Dietary Obese Rats (유도비만 흰쥐에서 발효 서목태가 미치는 생리활성)

  • Bae, Gui-jeong;Ha, Bae-jin
    • KSBB Journal
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    • v.30 no.6
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    • pp.339-344
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    • 2015
  • This study was to examine the lipid metabolism of fermented Rhynchosia nulubilis (FRN) in obese rats. The abnormal content of blood lipids often results in metabolic diseases, such as obesity and hyperlipidemia. Seven weeks female Sprague-Dawley rats were divided into four groups and fed high fat diets for 44 days. Also FRN was administered orally for 44 days at 7.5 ml/kg of body weight of rats. The effects of the lipid metabolism were evaluated by total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL), low density lipoprotein (LDL), glutamic pyruvate transaminase (GPT) and glutamic oxalacetic transaminase (GOT) levels in sera. The levels of TC, TG, LDL and GPT in FRN-treated groups were lower than those in obese groups. While HDL levels were significantly increased. These results demonstrated that FRN had improving effects of lipid metabolism in the obese rats, suggesting that FRN would be used as an ingredient of the useful functional products.

Antihyperlipidemic Activity of the Ethyl-acetate Fraction of Stereospermum Suaveolens in Streptozotocin-induced Diabetic Rats

  • Thirumalaisamy, Balasubramanian;Prabhakaran, Senthilkumar Gnanavadevel;Marimuthu, Karthikeyan;Chatterjee, Tapan Kumar
    • Journal of Pharmacopuncture
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    • v.16 no.3
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    • pp.23-29
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    • 2013
  • Objectives: Dyslipidemia in diabetes mellitus is a significant risk factor for the development of cardiovascular complications. The aim of this study was to evaluate the effect of the ethyl-acetate fraction of an ethanolic extract from Streospermum suaveolens on lipid metabolism in streptozotocin (STZ)-induced diabetic rats. Methods: Diabetes was induced by intraperitonial injection of STZ (50 mg/kg). Diabetic rats were treated with an ethyl-acetate fraction orally at doses of 200 and 400 mg/kg daily for 14 days. On the $15^{th}$ day, serum lipid profiles, such as total cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL), and high-density lipoprotein (HDL), were estimated in experimental rats. The atherogenic (AI) and the coronary risk (CRI) indices were also evaluated. Results: The ethyl-acetate fraction at doses of 200 and 400 mg/kg significantly (P < 0.001) and dose-dependently reduced serum cholesterol, triglycerides and LDL, but increased HDL towards near normal levels as compared to diabetic control rats. The fraction also significantly (P < 0.001) lowered the atherogenic index (AI) and coronary risk index (CAI) in a dose-dependent manner. Conclusion: The present study demonstrated that the ethyl-acetate fraction of Stereospermum suaveolens exhibits a potent antihyperlipidemic activity in hyperglycemic rats and suggests that the plant may have therapeutic value in treating the diabetic complication of hyperlipidemia.

Relationship between Physical activity and Cardiovascular Outcomes in the Korean Elderly: Review of Experimental Studies (노인의 규칙적 신체활동이 심혈관 기능에 미치는 영향 고찰)

  • Chae, Young Ran;Kim, Jeung-Im;Lim, Kyung Choon
    • Women's Health Nursing
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    • v.20 no.4
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    • pp.309-317
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    • 2014
  • Purpose: The purpose of this study was to review the relationship between physical activity and cardiovascular outcomes in the Korean elderly. Methods: Experimental studies were located using PubMed, CINAHL, PsycINFO, Cochrane, RISS, KISS, and KoreaMed. The selected studies for analysis were 20 articles of cardiovascular outcomes (total cholesterol, triglyceride, high density lipoprotein (HDL), low density lipoprotein (LDL), blood pressure, and pulse rate) from 515 articles. Results: One-group pretest-posttest design was the most common. The main physical activity was an aerobic exercise. Five of 14 studies reported a significant improvement of total cholesterol. Four of 14 studies found relationship between exercise and triglyceride. Eight of 12 studies reported a significant improvement of HDL, whereas 3 of 9 studies reported a significant improvement of LDL. In over 60% of selected studies, reported significant improvement of blood pressure. Conclusion: Based on the review, it suggests that regular physical activity of the elderly may improve cardiovascular outcomes.

Measuring Thresholds of Serum Lipid Level related to Hypertension and Age Using Receiver Operating Characteristic Curve in Korean Adult

  • Kim, Seong-Gil;Park, So-Hyun
    • Journal of the Korean Society of Physical Medicine
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    • v.9 no.3
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    • pp.301-305
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    • 2014
  • PURPOSE: The purpose of this study was to determine the optimal thresholds of serum lipid level related to hypertension according to age in Korean adults. METHODS: In total, 564 adults who visited the health examine center in general hospital were included. The blood pressure and lipid profiles of low density lipoprotein cholesterol(LDL), high density lipoprotein cholesterol (HDL), triglyceride(TG) were measured. Receiver operating characteristic (ROC) curve were used to establish optimal thresholds between blood pressure and lipid profiles. RESULTS: The optimal TG cutoff value were 110.50(mg/dl) in the 18-39 and 81.50(mg/dl) in the 40-59 age group, and optimal cutoff value of LDL were 126.50(mg/dl) in the 40-59 age group and 111.00(mg/dl) in the 60 and over age group. There was a negative correlation between HDL and hypertension, a higher HDL decreased hypertension. The optimal cutoff value of HDL was 49.50(mg/dl) in the 18-39 age group. CONCLUSION: The thresholds of hypertension were lower in LDL and TG with aging. This result indicated that elderly people needs to concern more about their lipid profiles to maintain healthy cardiovascular function.

Antihyperlipidemic Activity of Scutellaris baicalensis Georg., Coptidis japonica Makino and Rhei koreanum Nakai on Experimental Hyperlipidemia in Rats (고지혈증 랫트를 이용한 황금, 황련, 대황의 항고지혈 효과)

  • Ro, Hwan-Seong;Ko, Woo-Kyoung;Kim, Oon-Ja;Park, Kun-Koo;Cho, Young-Whan;Park, Hyoung-Sup
    • Journal of Pharmaceutical Investigation
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    • v.26 no.3
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    • pp.215-219
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    • 1996
  • Active component was sought among three herb medicines, which are used in combination as a traditional medicine prescribed for patients with hyperlipidemia related diseases. Antihyperlipidemic effect of this remedy has previously been shown model by the authors on the animal model. Hyperlipidemia was induced on male Wistar rats by keeping them on high lipid diet for one week, as previously described by the authors. Blood lipid profile was verified on these rats by measuring total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL) and low density lipoprotein (LDL). Then, the diet was changed to normal. At the same time, methanol extracts of Scutellaris baicalensis Georg.(radix), Coptidis japonica Makino(rhizoma) or Rhei koreanum Nakai(rhizoma) were given on daily basis, and changes in the blood lipid profile were monitored for 4 weeks. Methanol extract of Scutellaris baicalensis Georg. significantly reduced the TC value, implying the in vivo antihyperlipidemic effect.

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