• 성인간호학회지
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• 제19권3호
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• pp.339-352
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• 2007

Purpose: The purpose of this study was to investigate the effect of weight control program on body composition(body mass index and waist-hip ratio), blood pressure, serum lipids(total cholesterol, triglyceride, high density lipoprotein and low density lipoprotein) and self-regulation behavior in obese college women. Methods: Forty seven obese subjects were divided into experimental(22) and control(25) groups. The weight control program lasting 12 weeks consisted of a traffic-light diet, jumping-rope exercises, and behavior modification methods with e-mail counseling. The data were collected from 29 March to 17 September of 2004. The variables were assessed before and after intervention for 12 weeks in two groups. Then, those were repeated after a 12 week suspension of intervention in the experimental group. The data were analysed by the SPSS computer program. Results: BMI, HDL, LDL and self-regulation behavior levels showed significant differences between the experimental and control groups. While there were no significant differences in waist-hip ratio, blood pressure, total cholesterol and triglyceride. Conclusion: The weight control program had a positive effect on obese college women, and can be used to control obesity.

• 한국직업건강간호학회지
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• 제18권2호
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• pp.242-251
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• 2009

Purpose: To confirm the effect of tailored life style improvement program, provided by occupational health nurse for hypertensive workers on their blood pressure, self-efficacy, and life style changes in workplace. Method: The experimental and control group of thirty subjects each were randomly assigned for those who agreed to participate in the study among the pre-hypertensive workers. The tailored life style improvement program was provided to the experimental group and conducted once a week for 8 weeks. This program was composed of exercise and low salt diet to control high blood pressure and weight, and the measurement of carbon monoxide for non-smoking inducement. Result: In the experimental group, the systolic and diastolic blood pressure significantly decreased while self-efficacy increased after the program compared to the control group. Smoking and drinking habits of the experimental group were significantly decreased whereas exercise and nutritional habits were significantly improved compared to the control group. Conclusion: The tailored life style improvement program provided by occupational health nurses for the hypertensive workers was positively affected on their blood pressure, self-efficacy and life style changes in workplace.

• 대한간호학회지
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• 제34권5호
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• pp.739-750
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• 2004

Purpose: This study was to evaluate the effects of foot reflexology on blood pressure, serum lipids level and life satisfaction in essential hypertension patients. Method: The research design used was a nonequivalent control group pretest-posttest design. Foot Reflexology was used as the experimental treatment from June 23rd, 2003 until August 31st, 2003. Thirty-four subjects were assigned to an experimental group(18) and control group(16). Foot Reflexology was administered twice a week for 6 weeks and self foot Reflexology was administered twice a week for 4 weeks on the experimental group. Result: There was a significant decrease in systolic blood pressure but no significant decrease indiastolic pressure in the experimental group compared to the control group. The total cholesterol level in the experimental group compared to the control group was not significantly decreased after foot reflexology. However, the triglyceride level in theexperimental group compared to the control group was significantly decreased after foot reflexology. On the other hand, high density lipoprotein and low density lipoprotein levels in the experimental group compared to the control group was not significantly decreased after foot reflexology. Life satisfaction in the experimental group compared to the control group was significantly improved after foot reflexology. Conclusion: The results proved that foot reflexology was an effective nursing intervention to decrease systolic pressure, and triglyceride but not for the blood cholesterol and to improve life satisfaction. Therefore, blood cholesterol should be further evaluated in a larger group of subjects and for a longer period. Further research is regarded as necessary to evaluate and to compareeffects of self-foot reflexology and foot reflexology.

• 사상체질의학회지
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• 제25권2호
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• pp.81-97
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• 2013

Objectives The purpose of this study was to investigate the relationship between osteoporosis and cardiovascular risk factors according to Sasang constitution. Methods A total of 1773 participants, over 40 years old, were examined as part of a community-based cohort in Wonju city in Gangwon province of South Korea, from June 2006 to August 2009. We measured bone mineral density by Achilles ultrasonometer, serum levels of lipids, fasting blood sugar, insulin and other cardiovascular risk factors like blood pressure and waist circumference. Constitution was verified by a Sasang constitution specialist using the results of PSSC(Phonetic System for Sasang Constitution), facial photos and a simplified Sasang constitutional questionnaire. Results The prevalence rate was 11.2% in total participants, and 10.6% in Soyangin, 10.4% in Taeeumin and 13.9% in Soeumin. In general characteristics, educational and economic property and exercise were concerned with osteoporosis. Systolic blood pressure, pulse rate and total cholesterol were significantly high in osteoporosis group. Age and menopause were the key risk factors for osteoporosis. There was a significantly high prevalence in Soeumin for osteoporosis in men alone. Low physical activity was a major risk factor for osteoporosis. Waist circumference and hip circumference had significantly high odds ratio and weight had significantly low odds ratio. By Sasang constitution, Soyangin has the negative correlation with free fatty acid, Taeeumin has the negative correlation with waist circumference, pulse rate, systolic blood pressure, total cholesterol and low density lipoprotein and Soeumin has the positive correlation with body fat amount. Conclusions Regimens on osteoporosis should be considered according to Sasang constitution. Cardiovascular diseases should be considered according to Sasang constitution. Soeumin should be cautious of osteoporosis and gain weights and reasonable amount of fat food. Soyangin had better do exercise lower body and eat little food containing triglyceride. Taeeumin had better lose weights and eat little cholesterol food.

• Journal of Chest Surgery
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• 제23권6호
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• pp.1049-1056
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• 1990

The OXYREX hollow fiber membrane oxygenator developed by joint work of KIST and Green Cross Medical company has been evaluated by experimental investigation and clinical application, In this oxygenator gas exchanges occur through small pores of 0.1pm size which are distributed on 70% of surface of polypropylene hollow fiber. The Oxyrex membrane oxygenator consists of 36 thousand hollow fibers and it has 3.3m2 of gas exchange surface. The Oxyrex membrane oxygenator has unique blood flow path: blood enters the oxygenator passes between the hollow fibers and exits through outlet ports, that provides low transmembrane pressure drop. In the animal experiment and in vitro investigations of Oxyrex oxygenator, it showed low transmembrane pressure difference, effective heat exchanger performance, stable gas transfer function and less blood trauma. The Oxyrex oxygenator been used from March, 1990, to October, 1990, in 40 patients undergoing open heart operations. In the clinical applications of Oxyrex, adequate oxygenation[PaO2, 283$\pm$70mmHg] and carbon dioxide removal[PaCO2, 27\ulcorner6mmHg]were maintained under the condition of FiO2: below 0.6, Hct; 25%, perfusion flow; 2.4 L/min, gas flow: 2.1 L/min. During maximum 365 minutes of cardiopulmonary bypass[CPB] time period, the Oxyrex oxygenator maintained stable condition of PaO2, PaCO2 respectively and it also kept low plasma hemoglobin level. The complement proteins C3 and CH50 were not significantly changed pre to post CPB. There were no complications related to the oxygenator during and after the CPB.

• 보건교육건강증진학회지
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• 제23권4호
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• pp.1-12
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• 2006

Objectives: The aim of this study was to investigate the effects of DASH diet and law salt diet health education program on the blood pressure and the diet habit in the prehypertension group in Korea. Methods: The participants in this study were 141 people with prehypertension who were seen at a public health center. Data collection was done from March 11 to November 11, 2005 using interview with questionnaires. The participants took part in the diet health education program for 8 weeks. In order to evaluate the effectiveness of health education program, the variables of the diet such as hypertension, law salt diet and DASH diet were measured before and after the health education. The blood pressure was measured three times during the education. The collected data were analyzed with paired t-test and repeated ANOVA using SPSS 12.0 for Windows. Results: The diet habit variables after the education showed that their diet habit tend to the low salt diet and the DASH diet. The participants improved in their knowledge of hypertension and law salt diet, and they improved in the behavioral level of law salt diet and DASH diet after the health education for 8 weeks. Systolic and diastolic pressure were significantly decreased in prehypertension group after 8 weeks [10mmHg/6mmHg(p<0.001)]. Conclusion: These result suggest that the improvement in the level of behavior might be related with the change in blood pressure among the people having prehypertension in Korea.

• 혜화의학회지
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• 제19권2호
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• pp.173-177
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• 2011

We treated a 45 year-old male patient. He had Hypertension, Diabetes, Hyperlipidemia and Obesity. The main symptoms were Low-back pain, General body weakness, Abdominal discomfort. We diagnosed him as metabolic syndrome and prescribe Yagwanchunghyul-tang three times a day. We observed clinical symptoms Blood pressure, Capillary blood glucose, BMI, Body weight. Cholesterol, Triglyceride. After the treatment, The main symptom, blood pressure, capillary blood glucose(PP2hr), Hypercholesterol, Hypertriglyceride were improved. and BMI levels fell. This case shows that Yagwanchunghyul-tang has an effect on Metabolic syndrome like a Hypertension, Diabetes, Hyperlipidermia, Hypertriglyceride.

• The Korean Journal of Physiology
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• 제15권2호
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• pp.103-109
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• 1981

Ethanol 투여(投與) 용량(容量)에 따른 혈압(血壓)과 신기능(腎機能)의 변화(變化)를 알아보고자 흰쥐의 복부대동맥(腹部大動脈)에 catheter 를 삽입(揷入)하고 그 다른 끝을 목뒤로 끌어낸 후(後) 1주일(週日)이상 수술(手術)에서 회복(恢復)시킨 다음 실험(實驗)에 사용(使用)하였다. 실험직전(實驗直前)에 방광(膀胱)을 비운 뒤 metabolism cage에 넣어 안정(安靜)시킨 후(後) 60분(分)에 복부대동맥(腹部大動脈)의 catheter를 통(通)하여 평균동맥혈압(平均動脈血壓)(MAP)을 직접(直接) 측정(測定)하고 동맥혈액(動脈血液)과 뇨(尿)를 채취(採取)하였다. 곧 이어 ethanol 은 10 g% (저농도(低濃度)), 또는 30 g% (고농도(高濃度)) 용액(溶液)을, 대조실험(對照實驗)으로는 물을, 체중(體重) 100 g 당(當) 1 ml 씩 각각(各各) 경구(經口) 투여(投與)하였다. 용액투여후(溶液投與後) 3시간(時間)동안 MAP를 측정(測定)하고, 혈액(血液)은 매(每) 시간(時間)마다, 뇨(尿)는 90분(分) 간격(間隔)으로 채취(採取)하여 다음의 결과(結果)를 얻었다. 혈중(血中) ethanol 농도(濃度)는 ethanol 투여후(投與後) 1시간(時間)에 최고치(最高値)를 나타내고 (저농도(低濃度); $105.0{\pm}7.5,$ 고농도(高濃度); $214.7{\pm}20.2\;mg%$), 그후 직선적(直線的)으로 감소(減少)하였다. MAP는 물투여군(投與群)에서는 변화(變化)가 없었으나 ethanol 투여군(投與群)에서는 15분(分)부터 감소(減少)하기 시작(始作)하여 3시간(時間)동안 계속유의(繼續有意)하게 감소(減少)된 상웅(狀熊)를 나타내었다. 뇨량(尿量)은 ethanol 투여군(投與群)에서는 90분(分)동안에 유의(有意)한 증가(增加)를 보여주었고 (저농도(低濃度); $0.88{\pm}0.20{\rightarrow}1.04{\pm}0.22,$ 고농도(高濃度); $0.56{\pm}0.11{\rightarrow}1.35{\pm}0.18\;ml/1.5\;hr$), 180분(分)동안에는 뇨량(尿量)이 ethanol 투여전(投與前)보다 더 낮았다(저농도(低濃度); $0.25{\pm}0.06$, 고농도(高濃度); $0.22{\pm}0.06\;ml/1.5\;hr$). 물투여군(投與群)에서는 뇨량(尿量)이 계속(繼續) 감소(減少)하였다$(0.88{\pm}0.10{\rightarrow}0.59{\pm}0.09{\rightarrow}0.45{\pm}0.09\;ml/1.5\;hr)$. 이상(以上)의 결과(結果)는 ethanol의 혈중농도(血中濃度)가 높을수록 더 심(甚)한 혈압강하작용(血壓降下作用)을 나타내며, ethanol 로 인(因)한 이뇨작용(利尿作用)도 ethanol 량(量)이 증가(增加)함에 따라 뇨량(尿量)도 증가(增加)함을 보여 주었다.

• Journal of Preventive Medicine and Public Health
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• 제20권2호
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• pp.205-214
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• 1987

For the purpose of evaluating the effect of noise induced hearing loss on the blood pressure, a cross-sectional study was conducted in 481 manufacturing industrial workers in Pusan area consisted of 275 workers from noisier plant (over 90 dB(A), high exposed group) and 206 workers from less noisy plant (below 85 dB(A), low exposed group) from April to Decepmber in 1985. The summarized results were as follows; 1) The degree of hearing loss according to the audible frequency was most notable in 4,000 Hz. 2) The prevalence of hypertension was 14.8% in total examined subjects. And also in 40 dB(A) hearing lost workers, there was no significant difference between high exposed group as 15.5% and low exposed group as 15.8%. 3) In 3 models analyzed by multiple regression technique to obtain the complexed extents of risk factors related to the diastolic blood pressure, especially model III which contain age, body mass index, smoking, alcohol and family history of hypertension, duration of work, noise exposure level and degree of hearing loss in high exposed group was most remarkable compared to the others. 4) The most potential predictor related to the diastolic pressure in high exposed group was the degree of hearing loss. And the next were body mass index, familial history of hypertension and age in order. But in the case of low exposed group, the potential predictors were body mass index, age and familial history of hypertension.

• The Korean Journal of Physiology
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• 제24권2호
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• pp.261-268
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• 1990

It has long been suggested that the cardiac atrium is a low pressure volume receptor controlling body fluid volume and blood pressure. Recently, the cardiac atrium has been found to contain a family of powerful peptides. To clarify the relationship between high blood pressure and the biologically active atrial peptides, experiments were done to define the characteristics of atrial natriuretic peptide secretion in the isolated perfused atria of renal hypertensive rats. Higher concentrations of plasma atrial natriuretic peptide and renin activity were observed in the two-kidney, one clip hypertensive rat compared to the normotensive rat. Atrial volume changes in response to pressure elevations were attenuated in hypertensive rats compared to normotensive rats. Incremental response to atrial volume changes in ANP secretion was accentuated in hypertensive rats. These date suggest that the accentuated atrial natriuretic peptide response to volume changes of hypertensive rats may be a physiological or pathphysiological adaptation to the high blood pressure and may be, at least in part, responsible for the elevated levels of plasma atrial natriuretic peptide observed in hypertensive rats.