• 대한치과마취과학회지
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• 제11권2호
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• pp.146-152
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• 2011

Background: Elderly patients with progressive dementia including Alzheimer's disease (AD) are more and more often scheduled to undergo general anesthesia for various pathologies including dental problem. But, there is high risk of deterioration of underlying mental diseases and other co-morbidities. So it is important to implement preventive strategies and take adequate measures to minimize negative perioperative events in these patients. Methods: We reviewed the 17 cases of 11 patients with AD who underwent ambulatory general anesthesia for dental treatment at the clinic for the disabled in Seoul National University Dental Hospital. Results: The mean age was 68 (57-81) years. All of them were diagnosed with AD and some had hypertsnsion, bronchiectasis, urinary incontinence. For anesthesia induction, 3 cases (1 patient) was needed physical restraint, but others showed good or moderate cooperation. Drugs used for anesthesia induction was thiopental (11 cases), propofol (3 cases) and sevoflurane (3 cases). All patients received nasotracheal intubation without difficulties. Mean total anesthetic time was 3 hour 44 min ${\pm}$ 60 min and staying time at PACU was 83 ${\pm}$ 34 min. All the patients except one who showed hypertension discharged without any complication. There was no death or long term hospitalization because of severe complications. Conclusions: If general anesthesia is needed, pertinent diagnostic tests and workup about other medical problems, and appropriate anesthetic planning are essential for safety.

• 한국구조물진단유지관리공학회 논문집
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• 제15권1호
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• pp.263-270
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• 2011

이 연구에서는 프리캐스트 콘크리트용으로 공장에서 생산되며 그 동안 국내에서 많이 사용되어온 음이온계 계면활성제의 일종인 나프탈렌 설폰산염계(Poly-Naphthalene Sulfonate Type) 혼화제와 국내 J사에서 개발된 조강형 폴리카본산계(Polycarboxilic Type) 혼화제인 WF2000의 성능을 평가하였다. 실험결과에 의하면, WF2000은 PNS계보다 20% 줄어든 사용량에도 제품이 가지고 있는 높은 감수율과 고온에서 콘크리트 응결의 촉진효과 및 우수한 분산작용으로 인하여 작업성의 개선되었으며 PHC 파일의 조기강도와 장기강도 발현에 유리하였다. 그리고 감수력과 유지력의 조절이 가능하여 원재료의 변동 및 환경조건의 변화에 적절한 대응이 가능한 혼화제로 하절기의 생산성과 작업성 저하 그리고 성형성 불량의 문제 및 동절기의 응결지연으로 인한 조기강도의 저하에 대한 문제 해결 등에 유리하였다.

• 한국산학기술학회논문지
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• 제16권6호
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• pp.4298-4307
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• 2015

최근 콘크리트 구조물의 내구성 저하에 따른 성능저하로 유지 보수나 보강등에 상당한 비용이 증가함에 따라 콘크리트의 고유 특성인 균열 저감에 대한 연구가 필요한 실정이다. 특히 장기간 운영에 따른 지하 전력구의 노후화로 유지 보수에 어려움이 상존함에 따라 전력구 설계단계에서 균열을 획기적으로 저감할 수 있는 저수축 콘크리트용 수축저감제 기술 개발이 필요하다. 본 연구는 콘크리트 구조물의 내구성 저하에 따른 균열을 방지하고자 균열을 획기적으로 저감할 수 있는 저수축 콘크리트를 개발하기 위한 것으로 수축저감 물질을 선정하고 모르타르 및 콘크리트 특성을 검토한 결과 클리콜계의 경우 압축강도 특성 및 건조수축 길이변화 실험결과에서 우수한 것으로 나타나 수축저감제로서의 가능성을 확인하였다. 추후 수축저감제의 범용적인 적용성 검토를 위하여 수축저감제의 사용량 및 사용재료 변화 등에 대한 다양한 재료변수 요인 검토를 통하여 수축저감제의 성능 검토가 필요할 것으로 사료된다.

• International Journal of Industrial Entomology and Biomaterials
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• 제22권2호
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• pp.65-74
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• 2011

The Scarites aterrimus (Coleoptera: Carabidae), is one of the carabid beetles dwelling exclusively on coastal sandy dunes. Habitat deterioration and equivalent activity have greatly concerned population declines in several species dwelling on the coastal sandy dunes. As a first step to establish long-term conservation strategy, we investigated the nation-wide magnitude and nature of genetic diversity of the species. As a first step, we sequenced a portion of mitochondrial COI gene, corresponding to "DNA Barcode" region (658 bp) from a total of 24 S. aterrimus individuals collected over nine sandy dunes belonging to four Korean provinces. The sequence analysis evidenced moderate to low magnitude of sequence diversity compared with other insect species distributed in Korean peninsula (0.152% to 0.912%). The presence of closely related haplotypes and relatively high gene flow estimate collectively suggest that there had been no historical barriers that bolster genetic subdivision. Population decline was postulated on the basis of several missing haplotypes that are well found in the species with a large population size. This interpretation is consistent with field observation of small population size in the coastal sandy dune habitats. The highest genetic diversity estimates were found in the coastal sand dune population of Seogwipo, Jeju Island, justifying a prior attention to the population, in order to sustain overall genetic diversity of the species. Further scrutinized study might be required for further robust conclusion.

• 한국지하수토양환경학회지:지하수토양환경
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• 제26권6호
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• pp.165-175
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• 2021

Groundwater is used in many areas in food industry such as food manufacturing, food processing, cooking, and liquor industry etc. in Korea. As groundwater occupies a large portion of food industry, it is necessary to predict deterioration of water quality to ensure the safety of food water since using undrinkable groundwater has a ripple effect that can cause great harm or anxiety to food users. In this study, spatiotemporal data aggregation method was used in order to obtain spatially representative data, which enable prediction of groundwater quality change in a small watershed. In addition, a highly reliable predictive model was developed to estimate long-term changes in groundwater quality by applying a non-parametric segmented regression technique. Two pilot watersheds were selected where a large number of companies use groundwater for food water, and the appropriateness of the model was assessed by comparing the model-produced values with those obtained by actual measurements. The result of this study can contribute to establishing a customized food water management system utilizing big data that respond quickly, accurately, and preemptively to changes in groundwater quality and pollution. It is also expected to contribute to the improvement of food safety management.

• 한국산학기술학회논문지
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• 제20권7호
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• pp.102-110
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• 2019

본 연구는 건강보험공단의 기준에 의해 부분도움 또는 완전도움이 필요한 등급을 받은 정신적, 신체적 기능장애를 가진 노인을 대상으로, 고무의 탄성을 이용하여 관절과 근육이 무리를 덜 주는 저항성 운동프로그램들 개발하고, 이 운동이 노인의 보행능력, 균형능력 및 근력 향상에 미치는 효과를 분석한 연구이다. 경기, 충청권의 주간보호센터 세 곳을 대상으로 노인들 58명에게 12주간의 운동 프로그램을 진행한 후, 운동 참여 전과 후의 수치에 대해 종속 t-검증을 실시하였다. 그 결과 전체 참여자들이 보행능력, 균형능력, 근력에서 평균적인 향상을 보였다. 특히 모든 등급에서 검증된 균형능력의 유의한 향상(p<.01)은 균형능력이 일상생활 능력을 향상시키고 낙상 위험을 감소시킨다는 측면에서 노인 삶의 질 향상의 의미가 크다고 할 수 있다. 따라서 본 운동프로그램을 전체 노인으로 대상을 확대하고 활성화시킨다면, 건강한 노인이 치료가 필요한 취약계층으로 이동하는 것을 방지하고 허약노인이 장애노인으로 진행되는 것을 지연시킬 수 있어 개인적, 국가적 손실을 최소화할 수 있는 예방적 방법 중 하나가 될 것으로 기대된다.

• Structural Engineering and Mechanics
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• 제77권2호
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• pp.197-215
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• 2021

Under a severe environment of multiple hazards such as earthquakes and winds, the life-cycle performance of engineering structures may inevitably be deteriorated due to the fatigue effect caused by long-term exposure to wind loads, which would further increase the structural vulnerability to earthquakes. This paper presents a framework for evaluating the lifetime structural seismic performance under the effect of wind-induced fatigue considering different sources of uncertainties. The seismic behavior of a high-rise steel-concrete composite frame with buckling-restrained braces (FBRB) during its service life is systematically investigated using the proposed approach. Recorded field data for the wind hazard of Fuzhou, Fujian Province of China from Jan. 1, 1980 to Mar. 31, 2019 is collected, based on which the distribution of wind velocity is constructed by the Gumbel model after comparisons. The OpenSees platform is employed to establish the numerical model of the FBRB and conduct subsequent numerical computations. Allowed for the uncertainties caused by the wind generation and structural modeling, the final annual fatigue damage takes the average of 50 groups of simulations. The lifetime structural performance assessments, including static pushover analyses, nonlinear dynamic time history analyses and fragility analyses, are conducted on the time-dependent finite element (FE) models which are modified in lines with the material deterioration models. The results indicate that the structural performance tends to degrade over time under the effect of fatigue, while the influencing degree of fatigue varies with the duration time of fatigue process and seismic intensity. The impact of wind-induced fatigue on structural responses and fragilities are explicitly quantified and discussed in details.

• Nutrition Research and Practice
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• 제15권2호
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• pp.173-186
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• 2021

BACKGROUD/OBJECTIVES: Alzheimer's disease (AD) is the most common cause of dementia in the elderly. Due to the increased incidence of dementia, there is a corresponding increase concerning the importance of AD. In this study, we investigated the protective effects conferred by Zizyphus jujuba (Zj) and Zizyphus jujuba fermented by yeast (Zj-Y), on cognitive impairment in an AD mouse model. MATERIALS/METHODS: AD was induced by injecting amyloid beta25-35 (Aβ25-35) in ICR mice, and subsequently 200 mg/kg Zj or Zj-Y was administered daily for 14 days. The cognitive ability of AD mice was observed through behavioral experiments in T-maze, novel object recognition, and Morris water maze tests. We subsequently measured the levels of malondialdehyde (MDA), nitric oxide (NO), aspartate aminotransferase, and alanine aminotransferase in either tissues or serum. RESULTS: In behavioral tests, deterioration was revealed in the short- and long-term learning and memory functions in the Aβ25-35-injected control group compared to the normal group, indicating that Aβ25-35 injection impairs cognitive functions. However, administration of Zj and Zj-Y improved cognitive function in mice, as compared to the Aβ25-35-injected control mice. In addition, the Aβ25-35 induced elevations of MDA and NO in the brain, kidney, and liver were suppressed after exposure to Zj and Zj-Y. Especially, Zj-Y showed stronger scavenging effect against MDA and NO, as compared to Zj. CONCLUSIONS: Results of the present study indicate that Zj-Y exerts a protective effect on cognitive impairment and memory dysfunction, which is exerted by attenuating the oxidative stress induced by Aβ25-35.

• 마이크로전자및패키징학회지
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• 제29권2호
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• pp.1-10
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• 2022

최근 반도체 소자는 모바일 전자제품과 wearable 및 flexible한 소자와 기판의 다양한 활용으로 많은 분야에서 폭넓게 사용되고 있다. 이들 반도체 칩 접합 공정 중 기판과 솔더의 열팽창 계수(CTE)의 차이와 기판 및 부품 전체에 인가되는 과도한 열 영향은 소자의 성능 및 신뢰성에 영향을 주며, 최종적으로 휨(warpage) 현상 및 장기 신뢰성 저하 등을 초래한다. 이러한 문제점을 개선하기 위해 저온에서 공정이 가능한 저융점 솔더에 대한 연구가 활발히 진행되고 있다. Sn-Bi, Sn-In 등 다양한 저융점 솔더 합금 중 Sn-Bi 솔더는 높은 항복 강도, 적절한 기계적 특성 및 저렴한 가격 등의 이점이 있어 유망한 저온 솔더로 각광받고 있다. 그러나 Bi의 높은 취성 특성 등 단점으로 인해 솔더 합금의 개선이 필요하다. 본 review 논문에서는 다양한 미량 원소와 입자를 첨가하여 Sn-Bi 소재의 기계적 특성 개선을 위한 연구 동향을 소개하며 이를 비교 분석하였다.

• 한국전기전자재료학회논문지
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• 제35권5호
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• pp.439-444
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• 2022

Laser-induced plasmonic sintering of metal nanoparticles (NPs) is a promising technology to fabricate flexible conducting electrodes, since it provides instantaneous, simple, and scalable manufacturing strategies without requiring costly facilities and complex processes. However, the metal NPs are quite expensive because complicated synthesis procedures are needed to achieve long-term reliability with regard to chemical deterioration and NP aggregation. Herein, we report laser-induced Ag NP self-generation and sequential sintering process based on low-cost Ag organometallic material for demonstrating high-quality microelectrodes. Upon the irradiation of laser with 532 nm wavelength, pre-baked Ag organometallic film coated on a transparent polyimide substrate was transformed into a high-performance Ag conductor (resistivity of 2.2 × 10^-4 Ω·cm). To verify the practical usefulness of the technology, we successfully demonstrated a wearable transparent heater by using Ag-mesh transparent electrodes, which exhibited a high transmittance of 80% and low sheet resistance of 7 Ω/square.