• Title/Summary/Keyword: Long-Term Experiment

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An Experimental Study on the Resistance of Low-Heat Cement Mortar in Chemical Attack (저발열시멘트 모르터의 호학저항성에 대한 실험적 연구)

  • 문한영;신화철;김성수;강석화
    • Proceedings of the Korea Concrete Institute Conference
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    • 1998.04a
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    • pp.183-186
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    • 1998
  • This paper deals with 28, 56, 91 days age compressive strength and ratio of weight when OPC and Low-Heat cement mortar immersed in chemical solution. As a result of experiment, the resistance of Low-Heat Cement motar in chemical attack is more effective than that of OPC, because of lower $C_3$A content and Pozzolanic reactions. Especially in long term age compressive strength, Low-Heat cement mortar shows higher strength in all kind of chemical solution compared with compressive strength of OPC motar.

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Long Term Effect of High Glucose and Phosphate Levels on the OPG/RANK/RANKL/TRAIL System in the Progression of Vascular Calcification in rat Aortic Smooth Muscle Cells

  • Kang, Yang Ho;Jin, Jung Sook;Son, Seok Man
    • The Korean Journal of Physiology and Pharmacology
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    • v.19 no.2
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    • pp.111-118
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    • 2015
  • Osteoprotegerin (OPG), receptor activator of NF-${\kappa}B$ ligand (RANKL)/receptor activator of NF-${\kappa}B$ (RANK) axis, and TNF-related apoptosis-inducing ligand (TRAIL) participate in vascular calcification process including atherosclerosis, but their contributions under high glucose (HG) and phosphate (HP) condition for a long-term period (more than 2 weeks) have not been fully determined. In this study, we evaluated the effects of HG and HP levels over 2 or 4 weeks on the progression of vascular calcification in rat vascular smooth muscle cells (VSMCs). Calcium deposition in VSMCs was increased in medium containing HG (30 mmol/L D-glucose) with ${\beta}$-glycerophosphate (${\beta}$-GP, 12 mmol/L) after 2 weeks and increased further after 4 weeks. OPG mRNA and protein expressions were unchanged in HG group with or without ${\beta}$-GP after 2 weeks. However, after 4 weeks, OPG mRNA and protein expressions were significantly lower in HG group with ${\beta}$-GP. No significant expression changes were observed in RANKL, RANK, or TRAIL during the experiment. After 4 weeks of treatment in HG group containing ${\beta}$-GP and rhBMP-7, an inhibitor of vascular calcification, OPG expressions were maintained. Furthermore, mRNA expression of alkaline phosphatase (ALP), a marker of vascular mineralization, was lower in the presence of rhBMP-7. These results suggest that low OPG levels after long term HG and phosphate stimulation might reduce the binding of OPG to RANKL and TRAIL, and these changes could increase osteo-inductive VSMC differentiation, especially vascular mineralization reflected by increased ALP activity during vascular calcification.

Water Level Forecasting based on Deep Learning: A Use Case of Trinity River-Texas-The United States (딥러닝 기반 침수 수위 예측: 미국 텍사스 트리니티강 사례연구)

  • Tran, Quang-Khai;Song, Sa-kwang
    • Journal of KIISE
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    • v.44 no.6
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    • pp.607-612
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    • 2017
  • This paper presents an attempt to apply Deep Learning technology to solve the problem of forecasting floods in urban areas. We employ Recurrent Neural Networks (RNNs), which are suitable for analyzing time series data, to learn observed data of river water and to predict the water level. To test the model, we use water observation data of a station in the Trinity river, Texas, the U.S., with data from 2013 to 2015 for training and data in 2016 for testing. Input of the neural networks is a 16-record-length sequence of 15-minute-interval time-series data, and output is the predicted value of the water level at the next 30 minutes and 60 minutes. In the experiment, we compare three Deep Learning models including standard RNN, RNN trained with Back Propagation Through Time (RNN-BPTT), and Long Short-Term Memory (LSTM). The prediction quality of LSTM can obtain Nash Efficiency exceeding 0.98, while the standard RNN and RNN-BPTT also provide very high accuracy.

Long-term Application Effect of Silicate Fertilizer on Soil Silicate Storage and Rice Yield

  • Kim, Myung-Sook;Park, Seong-Jin;Lee, Chang-Hoon;Ko, Byong-Gu;Yun, Sun-Gang
    • Korean Journal of Soil Science and Fertilizer
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    • v.49 no.6
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    • pp.819-825
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    • 2016
  • Monitoring of soil fertility and crop productivity in long-term application of silicate fertilizers is necessary to use fertilizers efficiently. This study was conducted to investigate effects of continuous application of silicate fertilizer for rice cultivation from 1969 to 2014. The treatments were no silicate fertilizer treatments (N, NC, NPK, and NPKC) and silicate fertilizer treatments (N+S, NC+S, NPK+S, and NPKC+S). The 46-yr input of $2\;ton\;ha^{-1}yr^{-1}$ of silicate fertilizer increased pH 0.6 ~ 1.1 and exchangeable Ca $2.0{\sim}2.4cmol_c\;kg^{-1}$ in silicate fertilizer treatments (N+S, NC+S, NPK+S, and NPKC+S) compared with no silicate fertilizer treatments (N, NC, NPK, and NPKC) because silicate fertilizer included Ca component. Also, available silicate concentrations of silicate fertilizer treatments (N+S, NC+S, NPK+S, and NPKC+S) increased $169mg\;kg^{-1}$ compared to no silicate fertilizer treatments. In Period II ('90~'14), the mean annual Si field balance varied from 62 to $175kg\;ha^{-1}yr^{-1}$ in silicate fertilizer treatments, indicating continuous accumulation of soil Si. Silicon uptake and grain yield of rice had greater differences between N treatment and N+S treatment than other treatments. This showed that the application of silicate fertilizer had greater effect in nutrient-poor soils than in proper nutrient soils. Thus the application of silicate fertilizer led to improvement the fertility of soil and increasement of rice production for the lack of soil nutrients.

Antidepressant effects of aqueous extract of saffron and its effects on CREB, P-CREB, BDNF, and VGF proteins in rat cerebellum

  • Asrari, Najmeh;Yazdian-Robati, Rezvan;Abnous, Khalil;Razavi, BiBi Marjan;Rashednia, Mrazieh;Hasani, Faezeh Vahdati;Hosseinzadeh, Hossein
    • Journal of Pharmacopuncture
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    • v.21 no.1
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    • pp.35-40
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    • 2018
  • Objective: The role of BDNF (brain-derived neurotrophic factor), CREB (cAMP response element binding) and VGF neuropeptide has been proved in antidepressant activity of long term saffron administration in the rat hippocampus. In this study we evaluated the role of these proteins in antidepressant activity of saffron in long term administration in the rat cerebellum. Methods: Saffron aqueous extract (40 and 80 mg/kg/day) and imipramine (10 mg/kg/day) were administered intraperitoneally for 21 days to rats. At the end of experiment, animals were sacrificed and cerebellums were separated. The protein levels of BDNF, VGF, CREB and P- CREB in the rat cerebellum were evaluated using western blot analysis. Results: Saffron aqueous extract (80mg/kg/day) caused significant increase in protein level of P-CREB in long term treatment in the rat cerebellum. The increases in the protein levels of VGF, CREB and BDNF were not significant. Conclusion: In summary, our results showed that antidepressant effect of saffron in rat cerebellum might be due to the enhanced phosphorylation of CREB.

Long-term Effects of Chemical Fertilizer and Compost Applications on Yield of Red Pepper and Soil Chemical Properties

  • Park, Young-Eun;Lim, Tae-Jun;Park, Jin-Myeon;Lee, Seong-Eun
    • Korean Journal of Soil Science and Fertilizer
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    • v.51 no.2
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    • pp.111-118
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    • 2018
  • A field experiment was conducted to investigate the effect of long-term (21-year) fertilizer and compost treatments on the yield of red pepper and chemical properties in top-dong, Suwon. Six treatments were chosen for this work: No fertilization (No fert.), NPK fertilizers (NPK), NPK and compost (NPK+Compost), NP and compost (NP+Compost), NK and compost (NK+Compost), PK and compost (PK+Compost). The yield of red pepper for 21 years indicated the significant differences among the No fertilization, the PK+Compost, and other treatments. The relative yield index was 13% and 59% respectively, for the No fertilization and the PK+Compost if the average yield of red pepper for the NPK regards $20,048kg\;ha^{-1}$ as the yield index with 100%. Soil organic matter at the compost applied treatments significantly increased compared with the No fert. and the NPK. The average increase rates of soil organic matter by applying the compost ranged from 0.69 to $0.73g\;kg^{-1}\;yr^{-1}$. Available phosphate content in soil appeared the significant increase all treatments excluding the No fert. It is estimated that the available phosphate in soil was increased by $7.0mg\;kg^{-1}\;yr^{-1}$ by applying compost and $14.2mg\;kg^{-1}\;yr^{-1}$ by applying P fertilizer. Application of K fertilizer or the compost alone, the NPK, the NP+Compost, continuously caused soil K depletion whereas K fertilization plus the compost maintained at a constant level of exchangeable K. The results indicated that the addition of compost to NPK fertilizer is recommended for the maximum stable yield for red pepper and enhancement of organic matter though it is also needed for adjusting of P and K fertilization.

Long-Term Tropical Residency Diminishes Central Sudomotor Sensitivities in Male Subjects

  • Lee, Jeong-Beom;Bae, Jun-Sang;Shin, Young-Oh;Kang, Jong-Chul;Matsumoto, Takaaki;Toktasynovna, Aliopva Aziza;Kaimovich, Alipov Gabit;Kim, Wan-Jong;Min, Young-Ki;Yang, Hun-Mo
    • The Korean Journal of Physiology and Pharmacology
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    • v.11 no.6
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    • pp.233-237
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    • 2007
  • Tropical natives (TROP) are capable of tolerating tropical heat because of their long-term adaptation to tropical environments. When exposed to heat stress, these natives tend to respond with lower sweat output, which is generally thought to be the result of heat acclimatization. The main objective of this study was to clarify central mechanisms inherent to suppressed thermal sweating in tropical natives (Malaysians) by comparing their sweating responses to those of temperate native (TEMP) (Koreans). This experiment was conducted in a thermoneutral climatic chamber ($24{\pm}0.5^{\circ}C,\;40{\pm}3%$ relative humidity). Heat loads were applied to each subject by the immersion of their lower legs in a hot water bath ($43^{\circ}C$ for 30 min). Sweat onset-time and sweat volume were compared between TROP and TEMP. The sweat onset-times on four selected points on the body ranged from 10.25 to 13.47 min in TEMP subjects, and from 16.24 to 17.83 min in TROP subjects (p<0.001). The local sweat volumes at the same sites ranged from 4.30 to $9.74 mg/cm^2$ in TEMP subjects, and from between 1.80 to $4.40mg/cm^2$ in TROP subjects (p<0.001). These results demonstrated a significant difference between TROP and TEMP subjects with regard to the manner in which they regulate their body temperatures when exposed to heat loads, and verified that long-term thermal adaptation blunts sweating sensitivities.

The Effect of Long-Term Fertilization on the Yield and Quality of Soybean (동일비료 24년 연용이 콩의 수량(收量) 및 품질(品質)에 미치는 영향(影響))

  • Park, No-Kwaun;Kim, Jae-Kyu;Seo, Young-Jin;Park, Seon-Do;Choi, Boo-Sull
    • Korean Journal of Soil Science and Fertilizer
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    • v.31 no.4
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    • pp.330-333
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    • 1998
  • This experiment was conducted to investigate the effect of long-term fertilization on the yield and quality of soybean. The yield of soybean was highest in the NPK+lime $1.5Mg\;ha^{-1}$ treatment. Carbohydrate content of soybean was high in the non-fertilizer treatment and crude protein content was high in the NPK+lime $1.5Mg\;ha^{-1}$ and NPK+silicate $1.5Mg\;ha^{-1}$ treatment, and crude lipid and ash content was high in the NPK+silicate $1.5Mg\;ha^{-1}$ treatment. The content of inorganic compounds were not different among treatments. Correlation between $P_2O_5$/T-N and carbohydrate, crude lipid was $-0.99^{**}$, $-0.94^{**}$ respectively. Correlation between Mn and carbohydrate was $0.95^*$, but others were not significantly different. Yield of soybean increased with lime application and protein content increased with silicate application.

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