• Title/Summary/Keyword: Locus of current

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Maturity-onset diabetes of the young: update and perspectives on diagnosis and treatment

  • Jang, Kyung Mi
    • Journal of Yeungnam Medical Science
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    • v.37 no.1
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    • pp.13-21
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    • 2020
  • Maturity-onset diabetes of the young (MODY) is a clinically heterogeneous group of monogenic disorders characterized by ß-cell dysfunction. MODY accounts for between 2% and 5% of all diabetes cases, and distinguishing it from type 1 or type 2 diabetes is a diagnostic challenge. Recently, MODY-causing mutations have been identified in 14 different genes. Sanger DNA sequencing is the gold standard for identifying the mutations in MODY-related genes, and may facilitate the diagnosis. Despite the lower frequency among diabetes mellitus cases, a correct genetic diagnosis of MODY is important for optimizing treatment strategies. There is a discrepancy in the disease-causing locus between the Asian and Caucasian patients with MODY. Furthermore, the prevalence of the disease in Asian populations remains to be studied. In this review, the current understanding of MODY is summarized and the Asian studies of MODY are discussed in detail.

Needs and Perceptions with Smart Technology Usage in the Elderly Care Facilities

  • Lee, Sun-Hyung;Lim, Choon-Hee;Lee, Seunghae
    • International Journal of Contents
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    • v.11 no.4
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    • pp.25-30
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    • 2015
  • The objective of this study is to identify the current state of usage and needs for Smart Technology (ST) in the elderly care facilities based on the point of view of staff members. Using survey via mails, data were analyzed with responses from top- or middle-level staff members working in 171 elderly care facilities located in Seoul, Gyeonggi-do, and Chungcheongnam-do. Results indicated that the most needed smart technology was home automation, followed by nurse call system and health monitoring. The technology with the highest feasibility was health monitoring, followed by nurse call system and video phone. Staff members in higher positions working in the elderly care facilities had the highest expectation in improving the image of their facilities by using ST, while they had low expectation for the fact that ST may increase the locus of control of the elderly. This study implies that ST implementations may vary depending on the level of responsibility of staff members and ST how people responsible for the elderly care facilities subjectively perceive the ST.

Stress response: Physiological and Behavioral Aspects (스트레스반응의 생 행동적 접근)

  • Kim, Keum-Soon
    • Perspectives in Nursing Science
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    • v.2 no.1
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    • pp.61-75
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    • 2005
  • Physical and psychological events can produce stress response in various degrees. Stress affects many aspects of physiology including both brain and peripheral elements which is represented as hypothalamus-pituitary-adrenal axis. Brain elements consist of corticotropin-releasing hormone(CRH), locus ceruleus(LC)-norepinephrine(NE)/autonomic system. Peripheral elements include pituitary-adrenal axis and the autonomic nervous system, which coordinate the stress response. Current trend of the stress researches is emphasizing the mechanisms of the stress response which is adaptive or become maladaptive. This review introduces 1) the concepts of stress, 2) physiological and behavioral aspects of stress responses, 3) the consequences of stress response, 4) the measurements of stress and 5) stress management for those interested in stress research.

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Simulation of Direct Torque Control of PM Synchronous Motor Drive (영구자석형 동기전동기의 직접토크제어 시뮬레이션)

  • Park gun-tae;Kim jae-hyung;Cha Duk-keun
    • Proceedings of the KIPE Conference
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    • 2001.07a
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    • pp.252-255
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    • 2001
  • In this paper, a mathematical model of permanent magnet synchronous motor (PMSM) fed by inverter with Direct Torque Control (DTC) Dynamic and steady state characteristics of PMSM is simulated and analyzed: electro-magnetic torque response, speed response, locus of the stator flux linkage. It is mathematically proven that the increase of electromagnetic torque in a permanent magnet motor is proportional the increase of the angle between the stator and rotor flux linkages, and, therefore, the fast torque response can be obtained by adjusting the rotating speed of the stator flux linkage as fast as possible. The simulation results verify the proposed control and also show that the torque response under DTC is much faster than the PWM current controlled drive.

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A case of mild CADASIL patient with a novel heterozygous NOTCH3 variant

  • Choi, WooChan;Hwang, Yang-Ha;Lee, Jong-Mok
    • Journal of Genetic Medicine
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    • v.19 no.1
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    • pp.38-41
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    • 2022
  • Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a single-gene disease caused by mutations in the neurogenic locus notch homolog protein 3 (NOTCH3) gene. The spectrum of clinical manifestations is broad, ranging from asymptomatic to typical ischemic stroke, and mainly depends on the location of the mutations. We describe the case of a 76-year-old female without apparent neurological deficits. However, brain magnetic resonance imaging revealed confluent lesions in the white matter. Direct sequencing of the NOTCH3 gene revealed a novel pathogenic mutation, c.811T>A, which results in a mild phenotype. Therefore, this report will expand the current knowledge in regards to the mutations that can cause CADASIL.

A Comparative Study of Differences in Environmental Awareness and Attitude between Korean and American College Students (한.미 대학생의 환경 인식 및 태도에 대한 비교 연구)

  • 이재영
    • Hwankyungkyoyuk
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    • v.13 no.1
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    • pp.87-95
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    • 2000
  • Despite the perceived significance of cross-cultural studies in environmental education, only few of this kind have been conducted in Korea because of several barriers such as additional communicative, fanancial and administrative efforts. This cross-cultural study was conducted to examine if there were any significant differences in environmental awareness and attitude toward current environmental issues. The results revealed that the American subjects appeared to be more concerned with environmental issues, have higher willingness to act, and have more internalized Locus of Control than the Korean subjects. Similar observations have been reported by Horsley's(1984) study that compared environmental attitudes among students from 10 different countries. This study, however, suggested possibility of alternative interpretations of the results from the perspective of social- and cultural pscyhology.

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Control Methods of the Pulse-Width Modualted Series Resonant Converter(PWN-SRC) (펄스폭 변조 직렬공진 컨버터의 제어연구)

  • 최현철
    • The Transactions of the Korean Institute of Power Electronics
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    • v.4 no.5
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    • pp.397-404
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    • 1999
  • In this paper, several control methods for the discontinuous mode PWlvl-SRC are investigated with the l linearized small signal model. In order to analyze the stability and dyncunic characteristics of the controlled s system, the root locus as a function of the normaliz떠 output current(]\iOC) for a given normalized output v voltage(NOV) is employed. FurLhem10re, in this paper, the “Optimal trajectory control of PWM-SRC" is newly p propos(xl and its good dvnamic performances are evaluated with other four control laws.laws.

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A Study On PIN Pulse Pattern Optimization In The Space Vector Notation Using Pulse Frequency Modulation (펄스 주파수 변조 방법을 이용한 공간 벡터 PWM 펄스 패턴최적화 기법에 관한 연구)

  • Jeon, Hi-Jong;Son, Jin-Geun;Kim, Dong-Joon;Lee, Suck-Tae;Choi, Woo-Jin
    • Proceedings of the KIEE Conference
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    • 1994.07a
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    • pp.307-312
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    • 1994
  • In this investigation the PFM(Pulse Frequency Modulation} will be used for optimizing PWM inverter pulse pattern. In traditional the pulse frequency of PWM is kept const. But modulated PWM's frequency in this study, the sinusoidal inverter's performance should be improved. The PWM pulsepatterns are definitely controlled so that the time-integral function of the voltage vectors in the space vector notation may show a circular locus. Further, performance index will be minimized because of minimizing distortion of output current. Finally, we will implement itusingsingle-chip microprocessor.

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Pre-service Teachers' Education Needs for AI-Based Education Competency

  • Mingyeong JANG;Hyeon Woo LEE
    • Educational Technology International
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    • v.24 no.2
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    • pp.143-168
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    • 2023
  • This study aims to analyze the perceptions and educational needs of pre-service teachers for the use of Artificial Intelligence (AI) in education. To this end, we collected survey data from 25 undergraduate students who were enrolled in a teacher education college in Seoul. The purpose of the survey was to measure the importance and current performance for instructional AI use based on the technological, pedagogical, and content knowledge (TPACK) framework, and to explore the priority of educational needs using Borich's needs analysis and the Locus for Focus model. The results of the study confirmed that Ethics and TPK competencies are prioritized. Additionally, the results indicated a high demand for practical knowledge that can be implemented in the practice of education. Based on the results, it is necessary to develop a teacher education program that focuses on ethical aspects and teaching strategy competencies in AI-based education.

The Design of a Position Controller for the Linear Brushless D.C. Motor Using New Auto-tuning PI control Method (새로운 Auto-Tuning PI 제어 방법을 이용한 선형 추진 브러시리스 직류 전동기에 대한 위치 제어기 설계)

  • 최중경;박승엽;전인효
    • Proceedings of the IEEK Conference
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    • 1999.06a
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    • pp.1121-1124
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    • 1999
  • Linear motor is able to produce line movement without rotary-to-line converter at the system required line moving. Thus Linear motor has no gear, screw, belt for line movement. Therefore it has some advantage which decrease friction loss, noise, vibration, maintenance effort and prevent decay of control performance due to backlash. This paper proposes the estimation method of unknown parameters from the BLDC Linear motor and determine the PI controller gain through this estimation. Each control movement that is current, speed, position control, and PWM wave generation is performed on Processor, which is DSP(Digital Signal Processor), having high speed performance. PI theory is adopted to each for controller for control behavior More fast convergence to command position is accomplished by applying the new velocity locus which derived from position error.

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