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Effect of Semisulcospira libertina Extract on Hepatic Injury Induced by D-galactosamine (다슬기 추출물이 D-galactosamine에 의해 손상된 간에 미치는 효과)

  • Park, Young Mi;Lee, Jong Eun;Seo, Eul Won
    • Korean Journal of Environmental Biology
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    • v.36 no.4
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    • pp.498-506
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    • 2018
  • The purpose of this study is to examine the restorative effect of Semisulcospira libertina extract, on damaged liver cells induced by D-galactosamine in rats. Treatment of damaged liver cells with S. libertina extract significantly reduced local fatty degeneration, and inflammatory cell necrosis, to levels similar with the undamaged control group. In addition, S. libertina extracts were found to reduce plasma levels of liver damage indicator enzymes, such as AST, ALT, LDH and ALP, to control levels. It also reduced lipid peroxides, and lipid contents within damaged liver tissues. This suggests that S. libertina extract has a restorative effect on liver cells, thus reducing release of damage-associated liver enzymes, and oxidative degradation of lipids. Also, S. libertina extracts were found to be involved in recovery of damaged cells from inflammatory response by suppressing expression of $TNF-{\alpha}$, which leads to tissue injury and necrosis, whereas inducing expression of HO-1 that protects cells during inflammation. Thus, S. libertina extract restores liver tissue from necrosis and fibrosis, as well modulates expression of inflammation-related genes against liver damage. Our findings suggest that S. libertina extract is an effective medicinal resource, for improving and recovering liver cells from hepatic injury.

Managerial Implications for Competitiveness Enhancement based on Perceptual Analysis of National Natural Heritages (자연유산 경쟁구조 분석과 관리적 시사점 -대학생 인식을 중심으로-)

  • Cho, Kyoung-shin;Um, Seo-ho
    • Korean Journal of Heritage: History & Science
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    • v.46 no.3
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    • pp.78-93
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    • 2013
  • The purpose of this study is to analyze college students' perception of national natural heritages, including natural monumentsand scenic sites, in comparison with the similar concepts of national parks and eco-landscape preservation areas, to suggest managerial implications to enhance competitiveness. The first objective of this study is to measure their attitude toward traveling each type of natural heritage and to rate the relative importance of the four types of heritages in terms of preservation. Natural monuments were perceived as the most strongly preserved type, while scenic sites were perceived as the least strongly preserved type. The second objective is to conduct a correspondence analysis to match the concepts of four types of natural heritages with 10 tourist attractions representing the types. It was found that college students have difficulty appropriately identifying the types of 10 tourist attractions. In addition, multi-dimensional scaling (MDS) was implemented to identify the similarities and differences of the four types of natural heritages and to produce a positioning map matching the four types of natural heritages with the six attributes representing each type as a tourist attraction. Natural monuments were perceived very differently from scenic sites and not very differently from eco-landscape preservation areas. There were a few associations between the four types of natural heritages and the six tourism attributes, implying that little effort is made to promote and position each type of natural heritage in terms of tourism. In conclusion, a public awareness program is required to enhance the brand image of natural monuments and scenic sites in comparison to national parks and eco-landscape preservation areas. In addition, local residents who live near the natural heritages should be bolstered to play a managerial role as supporters and contents providers for sustainability.

The Significance and Utilization of the Jungwon Historical and Cultural Area (중원역사문화권 설정의 의미와 활용 방안)

  • SEONG, Jeongyong;YANG, Sieun
    • Korean Journal of Heritage: History & Science
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    • v.54 no.3
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    • pp.204-227
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    • 2021
  • This paper proposed the validity and necessity of establishing the Jungwon Historical and Cultural Area by reviewing the historical characteristics of the name Jungwon and its temporal and spatial range. We also explored ways to utilize the Jungwon historical and cultural Area under the Special Act on the Maintenance of Historical and Cultural Areas. Jungwon, which means the center of the country, has strategic value as a key area connecting the Korean Peninsula to the north and south through the Geripryeong and Jukryeong. It also includes Chungju, which connects the Namhan and Bukhan Rivers . From the Mahan period, the areas of Cheongju and Jincheon, the Miho Stream basin to the west, and Chungju to the east were closely connected to each other. Afterwards, Baekje, Koguryo, and Silla engaged in a fierce battle to occupy the Jungwon area. Jungwon culture was born through the negotiation and fusion of the cultures of the three kingdoms. In particular, Silla continued to value the Jungwon area, demonstrated by the installation of Seowongyeong in Cheongju and Bukwongyeong in Wonju, centering on the Jungwongyeong. Since we have a historical view with a focus on ancient kingdoms, we have overlooked the full value of the history and culture of Jungwon. We need to recognize the importance of Jungwon area and think about how to utilize it. Therefore, we suggested in this paper that there be more public information services on the cultural heritage of Jungwon, the historical heritage experience, and the education programs for local residents. The development and operation of Jungwon's history, culture, and tourism contents, as well as the various academic research papers should be used to reveal the identity of the Jungwon historical and cultural area.

An Analysis of the Trends of Aromatherapy Researches in Chinese Literatures

  • Sun, Jiao-Jing;Kim, Kyeong-Ran
    • Journal of the Korea Society of Computer and Information
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    • v.26 no.1
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    • pp.239-251
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    • 2021
  • Traditional Chinese medicine has treated diseases and improved health in nature-based experience. Advanced nations began to be interested in naturopathic therapy in the late 19th century and it led China to research aromatherapy. This study searched previous researches related with aromatherapy and generally analyzed aroma oil, applied body parts, methods of use, and period of use. For research contents, scientific and society journals from 2000 to 2019 related with aromatherapy were searched in CNKI(www.cnki.com) and WANFANG DATE(www.wanfang.com). Finally, 30 papers were selected through 5-step qualitative evaluation and expert review and analyzed. Frequency and percentage(%) were calculated by means of the Excel 2013 Program and represented by a chart. The results of analyzing aromatherapy trends are as follows. All 30 papers were researched in the medical society. The most common symptom was irritation and anxiety that appeared in 13 papers. Lavender oil and bergamot oil were commonly used aroma oil. Commonly applied part and method were nose and nasal inhalation. For aroma oil associated with symptoms, lavender oil was the best in irritative, anxious, and negative emotion, depression, labor pain, sleep disorder, migraine, tension, and vomiting, pain, and fatigue after operation. Lemon, ginger, and peppermint oil was good for nausea. Based on the findings, this study derived applied body parts, methods of use, and period of use in aromatherapy. However, most aromatherapy was used for patients in the nursing and medical fields in the simple form of inhalation and local massage. This study will suggest a standard ground that aromatherapy is good for pain, colic pain, and tension in a short period but needs a long period for the efficacy of psychological and neurological symptoms.

Ammonium Behavior and Nitrogen Isotope Characteristics of 2:1 Clay Minerals from Submarine Hydrothermal System in the Wakamiko Crater of Kagoshima Bay, Southwestern Japan (일본 서남부 가고시마 와카미코 해저 열수환경에서 형성된 2:1 점토광물 내 암모늄 거동 및 질소동위원소 특성)

  • Jo, Jaeguk;Yamanaka, Toshiro;Shin, Dongbok
    • Economic and Environmental Geology
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    • v.54 no.1
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    • pp.151-160
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    • 2021
  • 2:1 clay minerals such as smectite incorporating ammonium were extracted to investigate the ammonium behavior and nitrogen isotope characteristics for two different sediment cores which were collected from shimmering sites on seafloor of the Wakamiko crater, southwestern Japan. Inorganic nitrogen contents in clay fraction were estimated by calibration curve based on consistently decreasing carbon and nitrogen ratio during the treatment to decompose organic materials, after removing inorganic carbon. The results show that the proportions of inorganic nitrogen for total nitrogen in clay fraction of SWS site(Core#1094MR: av. 18.2%) are higher than those in SES site(Core#1093MG: av. 11.5%). Relatively good crystallinity of the former suggests that exchangeable ammonium was transformed to non-exchangeable ammonium during more evolving diagenetic process. Nitrogen isotope variance of clay fraction(SES site: Core#1093MG: -4.4 ~ +0.2 ‰, av. -2.4 ‰; SWS site: Core#1094MR: -0.7 ~ +3.0 ‰, av. +1.5 ‰) during sequential decomposition of exchangeable ammonium suggests that heat flow derived from deep magma led to nitrogen isotope fractionation between dissolved ammonium and ammonia in the fluids involved in the formation of 2:1 clay mineral incorporating ammonium with local temperature variation.

The Effect of COVID-19 on Academic Satisfaction with Online Lecture Types and Contents -Perspectives of the Domestic and Foreign University Students- (코로나19로 인한 온라인 강의 형태와 콘텐츠가 학업 만족도에 미치는 영향 -국내외 대학생의 관점에서-)

  • Jo, Ji-Soo;Bae, Jeong-In
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.3
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    • pp.643-650
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    • 2021
  • The purpose of this study was to evaluate the impact of lecture content on the overall academic satisfaction in non-contact online classes. The study was conducted using an online survey of 107 university students attending metropolitan, local and foreign universities for a week from August 25th, 2020 to September 2nd, 2020. The analysis methods used included descriptive statistics and chi-square distribution, Fisher's exact test, linear by linear association, and logistic regression. The result of the study showed a significant decrease in Junior by 0.025 times compared to Senior (p<.05). Furthermore, a significant decrease in the impact of recorded lectures by 0.036 times compared to a hybrid of face-to-face and online lectures (p<.05). Compared to the response 'No', the number of student's responses of 'Yes' increased significantly by 31.358 times (p<.05). Additionally, a significant increase was seen in teaching methods by 19.709 times, and academic satisfaction by 7.989 times(p<.05). In conclusion, the results imply that the quality of lecture content is also important to improve the student's satisfaction with school life, but overall management is required in the areas of appropriate teaching methods, appropriate tuition, and evaluation methods.

Development and Implementation of Blockchain Appropriate Technology Science School Program of Europe-Korea Conference on Science & Technology (유럽-한인 과학기술학회의 블록체인 적정기술 과학교실 프로그램 개발과 적용)

  • Kim, Gahyoung;Choi, Kevin Kyeong-iI;Kim, Dowon;Son, Muntak;Kim, Byoung-Yoon
    • Journal of Appropriate Technology
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    • v.6 no.2
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    • pp.190-199
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    • 2020
  • The purpose of this study is to develop and implement the Appropriate Technology Science School program (ATSS) for youth operated by the Europe-Korea Conference on Science & Technology (EKC) since 2016. The development process consisted of pre-online management meetings, online and offline tutor training, operation of ATSS for youth, and satisfaction surveys. As a result of the development, the management team selected the mission-solving theme of "Transforming village using blockchain technology" through a pre-online meeting. The contents were reorganized according to the level of the participating tutees, and various learning activities such as co-building activities, games, and plays were newly introduced and developed first, and the programs developed through tutor training were demonstrated and improved. A total of 38 tutees and tutors from 6 countries participated in the 2018 ATSS. As a result, participants showed positive satisfaction overall. Tutees showed interest in dome co-building activities and hash function calculation activities, and tutors showed interest in lectures and monopoly games related to blockchain technology. The development and of the 2018 ATSS will contribute to the improvement of expertise in the operation of the EKC ATSS in the future to the management team. It will be an opportunity for tutors to experience that high-tech science and technology have a good impact on appropriate technology for the third world and community society. In addition, Tutees will be provided with an opportunity to indirectly experience the local situation and community society through a role play on the impact of blockchain technology on African villages.

A Study on Corporate Practices of Sustainable Corporate Citizenship Activities with Culture (문화를 통한 지속가능한 기업시민 실천을 위한 연구)

  • Son, Ye Ryeong
    • Korean Association of Arts Management
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    • no.56
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    • pp.119-144
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    • 2020
  • Not only the government, but private corporations have contributed a lot to growth and development of culture. Corporations have mainly made charitable, dispensational Macenat activities which are separate from their business activities. Such an one-sided and charitable method of supporting culture cannot last long - Part of the reason why the number of corporations supporting culture is decreasing lies in it. In order to have sustainable partnership with culture, first, corporations should figure out needs of the other party. Second, the activities of corporations to support culture should be corporate citizenship activities which are linked to their business activities. In particular, the existing concepts of CSR and CSV have some limits. CSR separates business activities of corporations and their social contribution activities, and CSV mainly assumes corporate social activities helpful to their business activities. But, the concept of corporate citizenship suggested in this study assumes corporate activities where corporations do their best not only in their business activities, but in solution of social problems. Accordingly, searching for the ways to practice corporate citizenship, this study analyzed global agendas of UN, UNESCO, and UCLG which suggest sustainable development with culture and corporate citizenship activities related with culture among corporations in Korea and other countries. The findings and hints of the analysis are as follows. First, corporate citizenship activities can contribute to building of unique images of corporations and improvement of brand identities. Second, such activities can help corporations to be born again as life style companies by using local cultures and their attractiveness. Third, corporations should have partnership with cultural associations creating shared values and provide them with continuous and stable support. And, cultural associations should try to grow with corporations through efforts to develop attractive contents and programs harmonious with management purposes of corporations.

Quality Properties Depending on Aging of Deabong Persimmon-fermented Liquor (매실 첨가 대봉감 발효 숙성주의 이화학적 특성)

  • Kwang Keun, Cho;Sang Won, Gal;Sang-Won, Lee
    • Journal of Life Science
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    • v.32 no.11
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    • pp.847-854
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    • 2022
  • The purpose of this study was to prepare Daebong persimmon-fermented liquor supplemented with Prunus mume fruit to promote the consumption of Daebong persimmon and to develop local specialties. As fermentation progressed, the alcohol content rapidly increased, whereas the sugar content decreased. With the production of CO2 from the second day of fermentation, the epidermis and flesh solids of the Daebong persimmons began mixing together and rose to the surface of the fermentation container. This phenomenon continued until the fourth and fifth days of fermentation; on the fifth day, the ethanol and sugar contents were 11.4% and 9.8°Brix, respectively. A concentration of 6 to 9% (w/w) P. mume fruit was found to be the optimal amount during Daebong persimmon fermentation. When the fermented liquor was stored for 60 days at 5℃, the pH and ethanol content showed no significant change during the aging period. As aging progressed, the content of sugar slowly decreased in both the control sample and in the one to which P. mume was added, showing 9.8 and 10.4 mg/ml at the eighth week post-aging, respectively. The total acid content was 0.79~0.81% at the beginning of aging but slightly increased to 0.84~0.86% in the second week of aging. As a result of the sensory test, the sour taste, sweetness, and flavor were slightly stronger in the P. mume fruit group than in the control group.

A Study on the Improvement of Vocational Training Program in Digital New Technology of Government (정부의 디지털 신기술 분야 직업훈련 개선에 관한 연구)

  • Lee, Woo Young;Lee, Moon-Su;Kim, Kug Weon
    • Journal of Practical Engineering Education
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    • v.14 no.2
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    • pp.405-411
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    • 2022
  • In this study, K-Digital Training program, which is a representative government project of vocational training for new digital technologies in response to the 4th industrial revolution, is analyzed and an improvement model is suggested. The K-Digital training project is rapidly expanding, with the number of training operators increasing by 7.1 times and training course programs by 8.5 times within three years of implementation, but there is a severe problem in that education and training programs are concentrated in the metropolitan. To solve this problem, a shared training model is proposed. This model is a plan to maximize the use of local human and material resources, to respond to new digital technologies through systematic composition and operation, and to enhance the stability and reliability of education and training. In each region, a sharing and cooperation model in the form of a consortium is established that jointly utilizes resources scattered by various training institutions such as instructors, training contents, and training infrastructure related to digital new technology. In addition, a training certification evaluation system is introduced to increase the credibility of the rapidly developing digital new technology training.