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Factors influencing the bio-impedance data in tissue segments along the three arm meridians: a pilot study

  • Lim, Chi Eung Danforn;Wong, Felix Wu Shun;Smith, Warren
    • CELLMED
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    • v.1 no.1
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    • pp.7.1-7.9
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    • 2011
  • Bioelectric impedance measurements have been reported to show significant variation between individuals. Different physiological conditions like thickened skin, obesity, and fluid retention can affect the impedance measurement. Therefore, it is important to learn what other factors can affect the measurements of impedance even in healthy individuals. Such information is a prerequisite for understanding the changes in impedance associated with acupuncture treatment. This study investigated the bio-impedance properties of tissue segments in the arms of a number of healthy subjects, so as to define the factors that might influence the variation of the bio-impedance data in acupuncture meridians studies. 51 healthy subjects were recruited through Liverpool Hospital, Sydney. Demographic data was collected from each subject including the age, sex, BMI, and time since most recent meal. Electrodes were applied to the forearms of each test subject. Measurements were done by a purpose-built Bio-Impedance Research Device (BIRD-I) which allowed the determination of core resistance (Rc) and core reactance (Xc) of each of the three meridian tissue segments on the anterior surface of the forearm. No significant difference was found in the core resistance attributable to age group, gender, BMI or meal intake. However, a statistically significant trend in increasing resistance from the radial to ulnar aspect of the forearm (p < 0.001) was found. No significant difference was found in the core resistance of test tissue segments among the 51 healthy subjects measured in this study. However, the trend of increasing core resistance from the radial to ulnar aspects of the arm deserves further investigation.

Investigation of health and safety impact from the 'Site BIM' tools in the live construction sites

  • Shah, Raj;Edwards, Joel
    • Journal of Construction Engineering and Project Management
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    • v.6 no.2
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    • pp.1-7
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    • 2016
  • Construction in the UK is the second most dangerous industry in terms of fatal and minor injuries according to the 2014 report of HSE. The use of mobile devices such as iPad, Tablets and Smart phones on the live construction projects is also on the increase in the UK due to the 2016 - Level 2 BIM (Building Information Modelling) implementation target, set by the UK Government. Hence, the use of such devices may become a distraction from work activities on the construction sites and will cause a major risk to the end users. The subject of improving safety of BIM use is widely researched, but there is a gap in knowledge about the actual use of the mobile devices and perception of 'Site BIM', on the construction site activities. The main gap identified in the 'Site BIM' is the health and safety aspect of using such devices on the construction sites. A safer way of working with such devices needs to be identified to avoid any potential site hazards and fatalities before the widespread use of the devices are found on the construction projects. In that context, the paper is aimed to highlight the safety issues that are required to address for the successful implementation of the mobile devices for safer use of the 'Site BIM'. Questionnaire survey was used to collect the site information among construction professionals in the UK. The survey findings suggested that a proactive approach may be helpful to stop potential hazards and risks causing by the use of mobile devices and potential measures need to be identified before any injuries and incidents occur. The paper concludes that training, changing size of mobile devices and ensuring a separate induction training for 'Site BIM' tools will improve the health and safety of the end users of the mobile devices at the live construction sites.

Genetic Characterization of Indigenous Goats of Sub-saharan Africa Using Microsatellite DNA Markers

  • Chenyambuga, S.W.;Hanotte, O.;Hirbo, J.;Watts, P.C.;Kemp, S.J.;Kifaro, G.C.;Gwakisa, P.S.;Petersen, P.H.;Rege, J.E.O.
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.4
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    • pp.445-452
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    • 2004
  • Genetic diversity of sub-Saharan African goats was assessed using 19 microsatellite markers. Breeds were sampled from eastern Africa (Maasai, Kigezi, Mubende, North West Highland, Arsi-Bale), southern Africa (Ndebele, Pafuri) and West Africa (West African Dwarf, Maure, Djallonke). European breeds (Grisons Striped, Toggenburg), Asian breeds (Mongolian Cashmere, Bandipur) and a Middle East breed (Arab) were also included. The mean number of alleles per locus and average gene diversity ranged from 5.26$\pm$0.464 (Djallonke) to 7.05$\pm$0.516 (Mubende) and from 0.542$\pm$0.036 (Pafuri) to 0.672$\pm$0.031 (Ndebele), respectively. The between breeds variation evaluated using $$G_{ST}$$ and $\theta$ were found to account for 14.6% ($\theta$) and 15.7% ($$G_{ST}$$) of the total genetic variation. The $D_{A}$ measure of genetic distance between pairs of breeds indicated that the largest genetic distance was between Pafuri and Djallonke while the lowest genetic distance was between Arsi-Bale and North West Highland. A neighbour-joining tree of breed relationships revealed that the breeds were grouped according to their geographic origins. Principal component analysis supported the grouping of the breeds according to their geographic origins. It was concluded that the relationships of sub-Saharan African goat breeds were according to their geographical locations implying that the goats of eastern Africa, West Africa and southern Africa are genetically distinct. Within each sub-region, goat populations could be differentiated according to morphological characteristics.

A Sensorless Rotor Position Estimation Scheme for IPMSM Using HF Signal Injection with Frequency and Amplitude Optimization

  • Lu, Jiadong;Liu, Jinglin;Hu, Yihua;Zhang, Xiaokang;Ni, Kai;Si, Jikai
    • Journal of Electrical Engineering and Technology
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    • v.13 no.5
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    • pp.1945-1955
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    • 2018
  • High frequency signal injection (HFI) is an alternative method for estimating rotor position of interior permanent magnet synchronous motor (IPMSM). The general method of frequency and amplitude selection is based on error tolerance and experiments, and is usually set with only one group of HF parameters, which is not efficient for different working modes. This paper proposes a novel rotor position estimation scheme by HFI with optimized frequency and amplitude, based on the mathematic model of IPMSM. The requirements for standstill and low-speed operational modes are met by applying this novel scheme. Additionally, the effects of the frequency and amplitude of the injected HF signal on the position estimation results under different operating conditions are analyzed. Furthermore, an optimization method for HF parameter selection is proposed to make the estimation process more efficient under different working conditions according to error tolerance. The effectiveness of the propose scheme is verified by the experiments on an IPMSM motor prototype.

Gene Expression in Zn-deficient U937 Cell Line : Using cDNA Microarray (아연결핍된 단핵구 U937 Cell Line에 있어서의 유전자 발현 탐색 : cDNA Microarray 기법 이용)

  • Beattie, John H.;Trayhurn, Paul
    • Journal of Nutrition and Health
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    • v.35 no.10
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    • pp.1053-1059
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    • 2002
  • In post-genome period, the technique for identifying gene expression has been changed to high throughput screening. In the field of molecular nutrition, the need for this technique to clarify molecular function of the specific nutrient is essential. In this study, we have tested the zinc-regulated gene expression in zinc-deficient U937 cells, using cDNA microarray which is the cutting-edge technique to screen large numbers of gene expression simultaneously. The study result can be used for the preliminary gene screening data for clarifying, using monocyte U937 cell line, molecular Zn aspect in atherosclerosis. U937 cells were cultured in Zn-adequate (control, 12 $\mu$M Zn) or Zn-deficient (experimental, 0 $\mu$M Zn) ESMI media during 2 days, respectively. Cells were harvested and RNA was extracted. Total RNA was reverse-transcriptinized and synthesized cDNA probe labeled with Cy-3. fluorescent labeled cDNA probe was applied to microarray slide for hybridization slide, and after then, the slide was scanned using fluorescence scanner. ‘Highly expressed genes’ in Zn-deficient U937 cells, comparing to Zn-adequate group, are mainly about the genes for motility protein, immune system protein, oncogene and tumor suppressor and ‘Less highly expressed genes’ are about the genes for transcription, apoptosis associated protein, cell cycle, and several basic transcription factors. The results of this preliminary study imply the effectiveness of cDNA microarray for expression profiling of a singly nutrient deficiency, specially Zn. Furthur study, using tailored-cDNA array and capillary endothelial cell lines, would be beneficial to clarify molecular Zn function, more in detail.

Hysteretic performance of SPSWs with trapezoidally horizontal corrugated web-plates

  • Kalali, Hamed;Hajsadeghi, Mohammad;Zirakian, Tadeh;Alaee, Farshid J.
    • Steel and Composite Structures
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    • v.19 no.2
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    • pp.277-292
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    • 2015
  • Previous research has shown that steel plate shear walls (SPSWs) are efficient lateral force-resisting systems against both wind and seismic loads. A properly designed SPSW can have high initial stiffness, strength, and energy absorption capacity as well as superior ductility. SPSWs have been commonly designed with unstiffened and stiffened infill plates based on economical and performance considerations. Recent introduction and application of corrugated plates with advantageous structural features has motivated the researchers to consider the employment of such elements in stiffened SPSWs with the aim of lowering the high construction cost of such high-performing systems. On this basis, this paper presents results from a numerical investigation of the hysteretic performance of SPSWs with trapezoidally corrugated infill plates. Finite element cyclic analyses are conducted on a series of flat- and corrugated-web SPSWs to examine the effects of web-plate thickness, corrugation angle, and number of corrugation half-waves on the hysteretic performance of such structural systems. Results of the parametric studies are indicative of effectiveness of increasing of the three aforementioned web-plate geometrical and corrugation parameters in improving the cyclic response and energy absorption capacity of SPSWs with trapezoidally corrugated infill plates. Increasing of the web-plate thickness and number of corrugation half-waves are found to be the most and the least effective in adjusting the hysteretic performance of such promising lateral force-resisting systems, respectively. Findings of this study also show that optimal selection of the web-plate thickness, corrugation angle, and number of corrugation half-waves along with proper design of the boundary frame members can result in high stiffness, strength, and cyclic performances of such corrugated-web SPSWs.

Mandibular shape prediction using cephalometric analysis: applications in craniofacial analysis, forensic anthropology and archaeological reconstruction

  • Omran, Ahmed;Wertheim, David;Smith, Kathryn;Liu, Ching Yiu Jessica;Naini, Farhad B.
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.42
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    • pp.37.1-37.13
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    • 2020
  • Background: The human mandible is variable in shape, size and position and any deviation from normal can affect the facial appearance and dental occlusion. Objectives: The objectives of this study were to determine whether the Sassouni cephalometric analysis could help predict two-dimensional mandibular shape in humans using cephalometric planes and landmarks. Materials and methods: A retrospective computerised analysis of 100 lateral cephalometric radiographs taken at Kingston Hospital Orthodontic Department was carried out. Results: Results showed that the Euclidean straight-line mean difference between the estimated position of gonion and traced position of gonion was 7.89 mm and the Euclidean straight-line mean difference between the estimated position of pogonion and the traced position of pogonion was 11.15 mm. The length of the anterior cranial base as measured by sella-nasion was positively correlated with the length of the mandibular body gonion-menton, r = 0.381 and regression analysis showed the length of the anterior cranial base sella-nasion could be predictive of the length of the mandibular body gonion-menton by the equation 22.65 + 0.5426x, where x = length of the anterior cranial base (SN). There was a significant association with convex shaped palates and oblique shaped mandibles, p = 0.0004. Conclusions: The method described in this study can be used to help estimate the position of cephalometric points gonion and pogonion and thereby sagittal mandibular length. This method is more accurate in skeletal class I cases and therefore has potential applications in craniofacial anthropology and the 'missing mandible' problem in forensic and archaeological reconstruction.

Exact integration for the hypersingular boundary integral equation of two-dimensional elastostatics

  • Zhang, Xiaosong;Zhang, Xiaoxian
    • Structural Engineering and Mechanics
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    • v.30 no.3
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    • pp.279-296
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    • 2008
  • This paper presents an exact integration for the hypersingular boundary integral equation of two-dimensional elastostatics. The boundary is discretized by straight segments and the physical variables are approximated by discontinuous quadratic elements. The integral for the hypersingular boundary integral equation analysis is given in a closed form. It is proven that using the exact integration for discontinuous boundary element, the singular integral in the Cauchy Principal Value and the hypersingular integral in the Hadamard Finite Part can be obtained straightforward without special treatment. Two numerical examples are implemented to verify the correctness of the derived exact integration.

Control-structure interaction in piezoelectric deformable mirrors for adaptive optics

  • Wang, Kainan;Alaluf, David;Mokrani, Bilal;Preumont, Andre
    • Smart Structures and Systems
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    • v.21 no.6
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    • pp.777-791
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    • 2018
  • This paper discusses the shape control of deformable mirrors for Adaptive Optics in the dynamic range. The phenomenon of control-structure interaction appears when the mirror becomes large, lowering the natural frequencies $f_i$, and the control bandwidth $f_c$ increases to improve the performance, so that the condition $f_c{\ll}f_i$ is no longer satisfied. In this case, the control system tends to amplify the response of the flexible modes and the system may become unstable. The main parameters controlling the phenomenon are the frequency ratio $f_c/f_i$ and the structural damping ${\zeta}$. Robustness tests are developed which allow to evaluate a lower bound of the stability margin. Various passive and active strategies for damping augmentation are proposed and tested in simulation.

Information Management by Data Quantification with FuzzyEntropy and Similarity Measure

  • Siang, Chua Hong;Lee, Sanghyuk
    • Journal of the Korea Convergence Society
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    • v.4 no.2
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    • pp.35-41
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    • 2013
  • Data management with fuzzy entropy and similarity measure were discussed and verified by applying reliable data selection problem. Calculation of certainty or uncertainty for data, fuzzy entropy and similarity measure are designed and proved. Proposed fuzzy entropy and similarity are considered as dissimilarity measure and similarity measure, and the relation between two measures are explained through graphical illustration.Obtained measures are useful to the application of decision theory and mutual information analysis problem. Extension of data quantification results based on the proposed measures are applicable to the decision making and fuzzy game theory.