• 대한중풍순환신경학회지
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• 제10권1호
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• pp.27-32
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• 2009

Object : The purpose of this study was to evaluate whether herbal medication may injure the liver function and kidney function in stroke patients. Method : We observed the serum AST, ALT, r-GTP, Creatinine, BUN of 78 patient from May 1. 2008 to June 30. 2009 admitted in Oriental Hospital of Daejeon University. Liver function and Kidney function tests were done on admission and before discharge. And all patients take herbal medicine with Western medicine. Result : AST, ALT, r-GTP, Creatinine, BUN decreased on discharge compared with the value on admission. The liver function and kidney function test score(AST, ALT, r-GTP, Creatinine, BUN) by administration period of herbal medication was not significantly changed. Conclusion : This study suggests that general herbal medication does not injure liver function and kidney function of human.

• Environmental Analysis Health and Toxicology
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• 제18권1호
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• pp.33-44
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• 2003

The possibility that liver and kidney function is adversely affected by current levels of environmental exposure to cadmium (Cd) as investigated in adult men and women in the general population in Seoul. From February to August in 2001, blood and morning spot urine samples were collected from 136 not occupationally exposed group (age range 20∼75 years) at 4 survey sites throughout seoul. Liver and kidney function parameters in serum and urine were examined by conventional methods. The questionnaire included factors, i.e. sex, age, smoking, alcohol, diet habit etc. The geometric mean values for Cd in blood (Cd-B) were 1.43 $\mu\textrm{g}$/1, It seemed prudent to conclude that liver and kidney function as not disturbed by the current environmental exposure to Cd in study.

• 사상체질의학회지
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• 제16권3호
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• pp.70-75
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• 2004

1. Objectives The Purpose of this study was to evaluate whether use of Sasang -Bang with western medication may injury the liver and the kidney function. We clinically studied the change Liver function test and BUN/Cr in patients who were hospitalized in Hana oriental Medical center for more than 1 month. 2. Methods The subjects were 33 patients admitted in Hana Oriental Medical center. All patients had been checked Liver Function Test and BUN/Cr three times every 2 weeks. 3. Results Aspartate Aminotransferase(AST), Alanine Aminotransferase(ALT), Gamma-Glutamyl transferase(GGT), Total billirubin, BUN, Creatine didn't change, compared with previous 2 weeks and 4 weeks. 4. Conclusions This study suggests that even though there are few toxic Sasang-Bang, in general, herbal medications with western medications which are prescribed by oriental medicine doctors should be carefully administered not to hurt liver and kidney function.

• 대한한의학방제학회지
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• 제24권3호
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• pp.225-231
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• 2016

Objectives : Liver cancer usually appears in the setting of underlying liver disease. Liver transplantation has potentials to improve survival for patients with liver cancer. This case report was designed to assess the clinical effect of Korean medicine on liver transplant patient's cerebral infarction.Methods : We provided Chiganpung Granule(Chodeungsan) to a patient who was 58 year old man complained of cognitive impairment and dysarthria. We checked the change of symptoms(K-MMSE, Aphasia Rapid Test) and liver function test and kidney function test.Results : We observed that Chiganpung Granule(Chodeungsan) decreased cognitive impairment and dysarthria. Liver function test and Kidney function test was improved.Conclusions : From the above results, it is considered that Korean medicine treatments is effective on liver transplant patient's cerebral infarction.

• 대한한의학원전학회지
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• 제24권3호
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• pp.71-74
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• 2011

Objective : Nutrient Qi, Blood Qi and Essencial Qi are the most significant qi in spleen, liver and kidney. However, the origins and functions of those qi are not quite detailed somehow. Method : I will try to find out the origins and functions of Nutrient Qi, Blood Qi and Essencial Qi through "Hwangdineijing". Result : The Nutrient Qi is the essence of spleen, Blood Qi is the essence of liver and Essencial Qi is the essence of kidney. Conclusion : The Nutrient Qi has function of nourishment in human body and digestion of water and food in spleen itself. The Blood Qi has a function to make each organ work in human body and to make free coursing in liver itself. Essential Qi has a function to store each essential qi of five viscera in human body and reproduction in kidney itself.

• 한방안이비인후피부과학회지
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• 제7권1호
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• pp.35-51
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• 1994

This is the study on causes and remedies of hearing disturbance in chinese medical journals(1991-1993). The results were as follows. 1. The causes of sudden deafness(突發性耳聾) were usually fire in the liver(肝火).phlegmatic fire(痰火), deficiency of the vital function and essence of the kidney(腎虛), blood stasis or sludge due to stagnation of vital energy stagnation(氣滯血瘀). Remove endogenous heat or fire method(淸瀉火熱法). circulation of phlegm and dampness(運化痰濕). using tonics to cure disease due to deficiency of vital essence of both the liver and the kidney(滋補肝腎) were used for each treatment. 2.The causes of menieres disease were usually mental disturbance due to phlegmatit fire(痰化上搖). dampness-phlegm long standing(痰濕內停), water-dampness retention(水濕停滯), Method of remove heat and circulation phlegm(淸熱化痰法), method of remove water and dampness(利水渗濕法), invigorate function of the spleen and circulation of dampness method(健脾化濕法) were used for each treatment. 3. The causes of toxico-deafness(中毒性 耳聾) were usually heart, liver and kidney functional weakness(心肝腎虛), vital essence and blood weakness(氣血虛弱). Remove obstruction in the flow and circulation phlegm(通窮化痰), reinforce vital energy and tonify blood (補氣活血), using tonics to cure disease due to deficiency of vital essence of both the liver and the kidney(滋補肝腎) were used for each treatment. 4. The causes of deafness (耳聾), tinitus(耳鳴) were usually mental disturbance due to wind and heat(風熱上搖). flaming up of excessive heat of the liver(肝火上亢). exhaustion seat of reproductive essence in kidney(腎精虧虛). Remove endogenous heat and disperse wind(淸熱疏風). remove the fire of liver(淸肝瀉火), through nourish kidney check exuberance of yang(滋腎潛陽), nourish kidney yang(補腎陽). replenish vital energy and improve essential substance(益精血), blood activate for treatment of blood stasis(活血化瘀) were used for each treatment. 5. The effects of mainly used drugs were classified into method of water and dampness remove medicine(利水渗濕藥), nourishing liver and kidney medicine(補肝腎藥), improve blood and vital energy activate medicine(活血行氣藥), through nourish yan medicine check exuberance of yang(滋陰潛陽藥).

• BMB Reports
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• 제36권2호
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• pp.154-158
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• 2003

Collagen is a family of proteins which consists of several genetically distinct molecular species and is intimately involved in tissue organization, function, differentiation and development. The purpose of this study was to investigate the concentration of different hydroxyproline (Hyp) fractions viz., total, free, peptide-bound, protein-bound, soluble- and insoluble-collagen hydroxyproline (Hyp) in various bovine tissues. Results showed that liver had the highest concentration of free Hyp followed by kidney, brain, spleen, lungs, muscle and heart. Liver also had the highest concentration of peptide-bound collagen Hyp followed by kidney, heart, spleen, lungs, brain and muscle. The concentration of protein-bound collagen Hyp was highest in the liver, followed by kidney, spleen, lungs, muscle, brain and heart. Total Hyp was highest in the liver, followed by kidney, spleen, brain, heart, muscle and lungs. Liver also had significantly high concentration of collagen as compared to other tissues examined (P<0.001). Spleen had the significantly higher concentration of soluble-collagen Hyp when compared to other tissues (P<0.001). This was followed by heart, muscle, lungs, brain, kidney and liver. Heart had the highest concentration of insoluble-collagen Hyp followed by lungs, kidney, liver, muscle, spleen and brain. The variation among the insoluble-collagen Hyp concentration of heart and muscle, spleen and brain was significant (P<0.001). We speculate that these differences could be due to the variation in turn over of rate of collagen metabolism in this species.

• 한국식생활문화학회지
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• 제18권6호
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• pp.592-600
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• 2003

Male rats were fed a purified diet containing one of 3 experimental diets, gelatinized rice starch that was not modified physically (RC), gelatinized physically modified rice starch using ultrasonic homogenizer(RU), gelatinized physically modified rice starch using hydroshear homogenizer(RH) during 28 days. RC was used as the rice starch control. Feeding a physically modified rice starch (RU) caused an increase in liver weight and RH increased RNA and protein contents in kidney significantly although there were no differences in food intakes compared to feeding a RC diet. The wet weight of liver, kidney and heart were higher in RU. The wet weights of fecal output of the rats fed RH was greater than in rice control group. The gut transit time was longer in the rats fed RH than in the rice control group significantly. Serum GOT, GPT, total bilirubin concentration were tended to be lower and blood urea nitrogen was significantly lower in RH group. The maturation index of kidney was higher in RU than in RC. These results suggest that physically modified rice starch improved growth performance and physiological functions in organs of growing rats.

• 동의생리병리학회지
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• 제21권4호
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• pp.822-834
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• 2007

This study searched the philosophical and medical thought of mutual understanding and human body. Mutual understanding is a fundamental problem in all branches of oriental studies. In other words, mutual understanding becomes the existential foundation of heaven-earth-human(三才). So human beings, heaven and the earth can't exist if there is no mutual understanding. It comes out the problem of self-consciousness in philosophy, and qi movement pattern like upward, downward, inward and outward movement in traditional korean medicine. Human beings have mutual understandings with heaven and the earth from a macroscopic standpoint, on the other side the human body from a microscopic standpoint. Qi movement is the mutual understanding and response of qi in human body, so with which the physiological functions and pathologic changes of viscera and bowels comes out. Therefore we want to present how to complete qi movement between viscera-bowels and organs to examine mutual understandings in human body closely. The results was summarized as follows; First, upbearing the clear yang and down bearing the turbid yin of spleen-stomach is main pivot of upward and downward of qi movement, and it is true form of mutual understandings between viscera and bowels, so upward, downward, inward and outward movement of whole viscera and bowels can be controlled by spleen-stomach. Second, by restraining relationships between downward heart fire and upward kidney water, heart fire and kidney water have close communications physiologically and pathologically as upper-lower, yin-yang and water-fire. Third, by restraining relationships between upbearing and effusion of liver and purification and down-sending of lung, liver and lung are outer circles of upward and downward movement, so they have antagonistic functions. Firth, by the relationships between upbearing the clear and down bearing the turbid of spleen-stomach and free coursing of liver, free coursing of liver-gallbladder is the essential requirement that it certify transportation and transformation of spleen-earth, so the disease of liver-gallbladder induce spleen-stomach disease pattern to affect its function of transportation and transformation. Fifth, by spleen and kidney, spleen yang is based on kidney yang, so the weakness of kidney yang can affect the function of transportation and transformation of spleen-stomach as it can't warm spleen earth. Sixth, by homogeny of liver-kidney, essence and blood of liver-kidney and ministerial fire of liver-kidney have mutal generation and limitation physiologically and they mutually are affected in pathologically.

• Mycobiology
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• 제37권1호
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• pp.37-42
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• 2009

Comparative effects of oyster mushrooms on plasma and fecal lipid profiles and on liver and kidney function were evaluated in hyper and normocholesterolemic rats. Feeding of hypercholesterolemic rats a 5% powder of oyster mushrooms (Pleurotus ostreatus, P. sajor-caju and P. florida) reduced the plasma total cholesterol level by 37%, 21% and 16%, respectively and reduced the triglyceride level by 45%, 24% and 14%, respectively. LDL/HDL ratio decreased by 64%, 45% and 41% for P. sajor-caju, P. ostreatus and P. florida fed rats, respectively. Mushroom feeding also reduced body weight in hypercholesterolemic rats. However, it had no adverse effect on plasma bilirubin, creatinin and urea nitrogen level. Mushroom feeding also increased the total lipid and cholesterol excretion in the feces. The present study reveals that feeding of 5% oyster mushroom powder does not have detrimental effects on the liver and kidneys rather may provide health benefits for the cardiovascular-related complication by decreasing the atherogenic lipid profiles.