• Clinical and Experimental Reproductive Medicine
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• v.48 no.4
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• pp.311-315
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• 2021

Objective: As clinicians and patients await consensus on intraovarian platelet-rich plasma (PRP) treatment, this project evaluated contemporary research trends in the literature. Methods: A PubMed/NLM search aggregated all ovarian PRP-related publications (n=54) to evaluate their scope, abstract utility, submission-to-publication interval, journal selected, article processing charge (APC), free reader access to full-text manuscripts, number and nationality of authors, and inclusion of international collaborators. The NIH Clinical Trials database was also audited. Results: Published output on intraovarian PRP has increased consistently since 2016, especially among investigators in Greece, Iran, USA, and Turkey. Between 2013 and 2021, 42 articles met the relevancy criteria, of which 40.5% reported clinical studies, small series, or case reports, 33% described experimental animal models, and 23.8% were opinion/review papers. Only two works included a placebo control group. The submission-to-publication interval (mean±standard deviation) was 130±96 days, there were 5.9±3.2 authors per project, and journals invoiced US $1,613±1,466 (range, $0-$3,860) for APCs. Conclusion: There was no correlation between APC and time to publish (Pearson's r=-0.01). Abstract content was inconsistent; sample size and patient age were often missing, yet free full-text "open access" was available for most publications (59.5%). The NIH Clinical Trials portal lists eight registered studies on "ovarian rejuvenation," of which two are actively recruiting patients, while four have been terminated or have an uncertain status. Two studies have concluded, with results from one posted to the NIH website. PRP and its derivatives for ovarian treatment show early promise, but require further investigation. Research is accelerating and should be encouraged, particularly placebo-controlled randomized clinical trials.

• Asian Spine Journal
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• v.12 no.6
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• pp.987-991
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• 2018

Study Design: Cross sectional study. Purpose: To assess the quality of anterior cervical discectomy and fusion (ACDF) videos available on YouTube and identify factors associated with video quality. Overview of Literature: Patients commonly use the internet as a source of information regarding their surgeries. However, there is currently limited information regarding the quality of online videos about ACDF. Methods: A search was performed on YouTube using the phrase 'anterior cervical discectomy and fusion.' The Journal of the American Medical Association (JAMA), DISCERN, and Health on the Net (HON) systems were used to rate the first 50 videos obtained. Information about each video was collected, including number of views, duration since the video was posted, percentage positivity (defined as number of likes the video received, divided by the total number of likes or dislikes of that video), number of comments, and the author of the video. Relationships between video quality and these factors were investigated. Results: The average number of views for each video was 96,239. The most common videos were those published by surgeons and those containing patient testimonies. Overall, the video quality was poor, with mean scores of 1.78/5 using the DISCERN criteria, 1.63/4 using the JAMA criteria, and 1.96/8 using the HON criteria. Surgeon authors' videos scored higher than patient testimony videos when reviewed using the HON or JAMA systems. However, no other factors were found to be associated with video quality. Conclusions: The quality of ACDF videos on YouTube is low, with the majority of videos produced by unreliable sources. Therefore, these YouTube videos should not be recommended as patient education tools for ACDF.

• Perspectives in Nursing Science
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• v.16 no.1
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• pp.45-54
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• 2019

Purpose: The purposes of this study was to review the literature on intervention for treating anxiety and depression among unmarried mothers living in facilities, and to understand core that could promote the development of more effective interventions. Methods: Key words in English and Korean were used to search through eight electronic databases-PubMed, Cochrane Library, EMBASE, CINAHL, RISS, DBpia, NDSL, and the National Assembly Library. Results: Ten studies were ultimately selected for the integrative review and were evaluated in terms of contextual and methodological quality. The studies consisted of seven quasi-experimental studies and three case report studies. The selected studies utilized music, art, forest therapy, dancing, education, and play programs to change mothers' perceptions, emotions, and behavior and to improve their relationships with their babies or others. Conclusion: It is important to consider mothers' self-awareness and emotional expression, and to improve their relationships with their babies or others as core elements when developing intervention programs for anxiety and/or depression among unmarried mothers living in residential facilities.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.14 no.1
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• pp.1-11
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• 2019

Objectives : The purpose of this study is to review clinical studies about the effect of chuna manual therapy (CMT) for peripheral facial paralysis in children. Methods : In this review, we searched 11 electronic databases (Pubmed, Cochrane Library, EMBASE, CINAHL, CAJ, Oasis, NDSL, KISS, RISS, KISTI, Dbpia); We concluded our literature search in April 23, 2019. We included only randomized controlled trials (RCTs) of testing CMT for peripheral facial paralysis in children. The methodological quality of each RCT was assessed using the Cochrane risk of bias tool. The meta-analysis was performed by synthesizing outcome data of total efficacy rate (TER). Results : After screening papers, a total of 6 RCTs were selected and analyzed. In the 6 RCTs, patients(n=15-60 per study) were randomized into groups for treatment and control. Specifically, the treatment group received CMT, while the control group was concurrently given usual care, such as acupuncture and medicine. The meta-analysis showed that the treatment group receiving CMT alone showed significant improvement in TER, compared to the control group receiving acupuncture therapy alone(P<0.05). And the treatment group receiving CMT combined with usual care showed positive results, in terms of TER, compared to the control group receiving usual care, but was not statistically significant(P>0.05). Conclusions : Our analysis suggests that CMT has therapeutic effects for peripheral facial paralysis in children. However, to confirm this result, further investigation accompanied by high quality studies is required.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.14 no.1
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• pp.119-134
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• 2019

Objectives : This study was conducted to investigate current research trends in Chuna manual therapy for the treatment of anxiety disorders in China. Methods : Using China Academic Journal and Pubmed, we performed a literature search of studies that were published from 2010 onwards. In total, 15 published studies were included in our analysis. Results : Of the 15 analyzed studies, nine were randomized controlled trials, two were non-randomized controlled trials, and four were case reports. Of the total patients, 80% were treated daily and received ${\leq}30$ treatments in total (excluding one study). In most studies(11 out of 15, 73.33%), the total effective rate of treatment was used to measure the outcome, with the Hamilton Anxiety Rating Scale being used most frequently. The case report demonstrated a therapeutic effect > 90%. In the control study, except for the two studies that reported significant improvement in the follow-up period, all of the measures were significantly improved (P<0.05) after treatment compared with before treatment. The An(按) and Rou(?) methods were the most frequently used. The Chuna method is categorized into four types: 1) It is performed around shoulders, neck, and face; 2) performed around abdomen, back, and neck; 3) performed on the whole body; 4) performed at the simply-stimulated acupoints. The most commonly used acupoint was Taiyang (Ex-HN 5), and the most frequently used acupoints were predominantly distributed in the head, face, and neck. Conclusions : This study demonstrated that Chuna manual therapy has significant effects when used as a treatment for anxiety disorder, warranting further investigation.

• Korean Journal of Clinical Pharmacy
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• v.29 no.2
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• pp.115-124
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• 2019

The purpose of this systematic review and meta-analysis was to assess the preventive effect of theophylline on acute kidney injury and the ameliorative effect of theophylline on renal function in asphyxiated neonates. A literature search of the PubMed/Medline, Embase, and Cochrane Library databases for information published up to February 2019 was conducted. All studies that reported the incidence rate of acute kidney injury, serum creatinine level, and glomerular filtration rate after the randomized administration of theophylline or placebo were included. In total, eight studies involving 498 neonates were eligible. The incidence rate of acute kidney injury was significantly lower in the theophylline group than in the placebo group (risk ratio [RR]: 0.42, 95% confidence interval [CI]: 0.32-0.55, p < 0.001). The changes in serum creatinine level in the theophylline group were significantly higher than those in the placebo group from the first day of life to 3 and 5 days of age (weighted mean difference [WMD]: -0.51, 95% CI: -0.62 to -0.40, p < 0.001, and WMD: -0.26, 95% CI: -0.34 to -0.18, p < 0.001, respectively). The changes in glomerular filtration rate in the theophylline group were significantly higher than those in the placebo group from the first day of life to 3 days of age and the last day of follow-up (WMD: 12.30, 95% CI: 9.39-15.21, p < 0.001, and WMD: 9.35, 95% CI: 6.43-12.27, p < 0.001, respectively). These results suggested that theophylline has a beneficial effect on the prevention of acute kidney injury in neonates with perinatal asphyxia.

• The Journal of the Korea Contents Association
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• v.19 no.1
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• pp.396-403
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• 2019

Metro stations are public places used by many people. If they use the station frequently, there is no struggling to find a way. But the first tourists or foreigners to visit are facing finding difficulties because of errors of the complicated sign and information. This study is the guidance of the metro station sign to provide effective information system and the research on the design improvement of metro station. In the first survey for this study I proceeded research about the concept of sign systems in metro station and literature search. In the second survey, I researched needs of the problems of the metro station users. In the third survey, I investigated Busan Metro Station's problems and design to improve the guide sign. In the survey results, users had a lot of difficulties in finding information because systematically increasing amount of information and guidance of the metro station. People can't find information because of sign indiscreet commercial advertising. Also they can get false information from sign without unity. To deal with these problems the metro station needs to improve design for a second-class citizen and refrain commercial advertising and design for information transfer capability.

• Journal of Oriental Neuropsychiatry
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• v.29 no.4
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• pp.239-253
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• 2018

Objectives: This is one of the manuals of East-West integrative medicine, which was created by the Committee on integrative medicine of Chung-Yeon Korean Medicine Hospital. To support clinical decision making and communication in the East-West cooperative treatment of mild cognitive impairment. Methods: Drafting was based on literature review from the MEDLINE, EMBASE, OASIS, and CNKI databases using search terms such as 'mild cognitive impairment', 'mild neurocognitive disorder', 'acupuncture', 'herbal medicine' and 'traditional Chinese medicine'. An amendment reflecting the goal of consultation and detailed treatment contents was made by reviewing the draft and holding discussion with the rehabilitation specialist of western medicine. The committee then agreed to adopt the manual through the process of review and feedback in addition to face-to-face discussions. Results: This manual contains the diagnosis of mild cognitive impairment, the goal of consultation, and the cooperative treatment contents of the East-West medicine for mild cognitive impairment. Conclusions: This manual provides significant information about the decision making process and contents of treatment in one medical institution for East-West cooperative treatment of mild cognitive impairment.

• Fire Science and Engineering
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• v.33 no.2
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• pp.164-172
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• 2019

This study examined the Post-Traumatic Stress Disorder (PTSD)-related variables of firefighters through a systematic literature review. Electronic databases were searched, including RISS, National Assembly Library, NDSL, KmBase. The search terms were PTSD, Post-Traumatic Stress, Post-Traumatic Stress Disorder and Firefighter. Eleven studies from 146 references screened were included. All studies were non-experimental and correlational analyses. The positive correlation factors were age, duration of work, traumatic events, frequency of mobilization, number and strength of traumatic events experienced, work burden, coping method, D-type personality, depression, and anger rumination. The negative correlation factors were resilience, social support, self-esteem. To improve the mental health of firefighters in the future, professional intervention programs should be constructed to improve resilience, social support, and self-esteem, which are protective factors of PTSD.

• Journal of Engineering Education Research
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• v.21 no.6
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• pp.99-107
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• 2018

The purpose of this study is to establish and propose educational vision of chemical engineering field in order to search for academic identity and future education direction in chemical engineering field. In order to achieve this research purpose, we investigate the literature and data on the vision, educational goals, and curriculum of the department of chemical engineering in domestic and foreign universities. We also analyze the SWOT of internal and external environmental factors respectively. The validity of the proposal was verified through delphi survey with delphi panels and the vision was developed by revising and improving upon the opinions of professionals. The vision is comprised of the value and mission of learning, the educational purpose, and the educational goal. The first stage is value and mission of chemical engineering. The educational purposes and the educational goals are divided into 'Department of Chemical Engineering' and 'Department of Chemical and Biological Engineering'. The application of the educational vision of chemical engineering field is as follows. First, we expect that the vision to be a valuable, philosophical, and theoretical basis for establishing educational objectives and goals in the field of chemical engineering. Hopefully, it will be used as a general education goal for the top-level education. Second, we hope that the vision will be used to develop customized vision, customized educational purpose, and educational goals that reflect the characteristics of region, departments, graduates, and educational needs in the field of chemical engineering. Finally, we hope that these results will be the starting point to discuss the educational vision in the department of chemical engineering.