• Title/Summary/Keyword: Liquid viscosity

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SMEDDS (Self-MicroEmulsifying Drug Delivery System) As An Intraurethral Prostaglandin E1 Delivery System

  • Lee, Sang-Kil;Jeon, Sang-Ok;Kang, Jae-Seon;Lee, Jae-Hwi;Choi, Young-Wook
    • Journal of Pharmaceutical Investigation
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    • v.37 no.5
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    • pp.291-295
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    • 2007
  • Prostaglandin $E_1\;(PGE_1)$ was formulated as two self-microemulsifying drug delivery systems (SMEDDS) composed of Cremophor $EL^{(R)}$ or Cremophor $ELP^{(R)}$ as a surfactant, ethanol as a cosurfactant and Labrafac $CC^{(R)}$ as an oil to develop liquid preparation for the treatment of erectile dysfunction. In pseudo-ternary phase diagram, viscous gel area and microemulsion area were defined. In the measurement of viscosity, the viscosity of two formulations increased gradually upon the addition of water and it decreased from the water contents over 40%. With excessive water, the present systems formed a microemulsion spontaneously. From these results, rte could expect that the present liquid $PGE_1$ SMEDDS formulations might stay within the urethra in the viscous state when contacting the moisture of the urethra and can be easily eliminated by urination. In long-term stability study, we could select one formulation more stable at the shelf storage condition of $4^{\circ}C$.

Wet adhesion and rubber friction in adhesive pads of insects

  • Federle, Walter
    • Journal of Adhesion and Interface
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    • v.5 no.2
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    • pp.31-42
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    • 2004
  • Many animals possess on their legs adhesive pads, which have undergone evolutionary optimization to be able to attach to variable substrates and to control adhesive forces during locomotion. Insect adhesive pads are either relatively smooth or densely covered with specialized adhesive hairs. Theoretical models predict that adhesion can be increased by splitting the contact zone into many microscopic, elastic subunits, which provides a functional explanation for the widespread 'hairy' design. In many hairy and all smooth attachment systems, the adhesive contact is mediated by a thin film of liquid secretion between the cuticle and the substrate. By using interference reflection microscopy (IRM), the thickness and viscosity of the secretion film was estimated in Weaver ants (Oecophylla smaragdina). 'Footprint' droplets deposited on glass are hydrophobic and form low contact angles. IRM of insect pads in contact showed that the adhesive liquid is an emulsion consisting of hydrophilic, volatile droplets dispersed in a persistent, hydrophobic phase. I tested predictions derived from film thickness and viscosity by measuring friction forces of Weaver ants on a smooth substrate. The measured friction forces were much greater than expected assuming a homogenous film between the pad and the surface. The findings indicate that the rubbery pad cuticle directly interacts with the substrate. To achieve intimate contact between the cuticle and the surface, secretion must drain away, which may be facilitated by microfolds on the surface of smooth insect pads. I propose a combined wet adhesion/rubber friction model of insect surface attachment that explains both the presence of a significant static friction component and the velocity-dependence of sliding friction.

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Evaluation of the Groutability through Microcrack and Viscosity Measurement Methods for Grouting Materials (미세균열 그라우팅 주입성능 및 재료의 점도 측정방법 평가)

  • Jin, Hyun-Woo;Ryu, Byung-Hyun;Lee, Jang-Guen
    • Journal of the Korean Geotechnical Society
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    • v.33 no.9
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    • pp.23-34
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    • 2017
  • In order to develop urban underground spaces, even microcracks should be reinforced. In this paper, the grouting injection performance for microcracks was investigated considering the viscosity and particle size of the grouting materials, injection pressure, and crack width. There are two types of typical grouting materials used for filling micro-cracks. One is a chemical liquid grouting material which is a solution type and the other is a cementitious grouting material which is a suspension type. The injection performance of the grouting materials for microcracks is generally influenced by the viscosity, and the injection performance of the cementitious grouting material is additionally affected by the particle size. From laboratory tests, the viscosity was calculated inversely to provide a suitable viscosity measurement method for each grouting material. The groutability ratio based on the relationship between the crack width and the particle size was evaluated to estimate the grouting feasibility of the cementitous grouting material through microcracks.

Study on the Optimized Condition of the Slot-Die Coating Process (슬롯다이 코팅의 최적화 조건에 관한 연구)

  • Seo, Eung Soo;Ye, Jungwoo;Hwang, Joong Kook;Shim, Jaesool;Chai, Young Suck
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.39 no.9
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    • pp.937-945
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    • 2015
  • In this paper, we study the coating performance according to the slot-die conditions in the coating process. The quality of the slot-die coating depends on factors such as feeding speed of film, the viscosity of liquid, and the pressure applied to the slot-die. In this study, we determine the optimum conditions for a stable coating by performing 2-D and 3-D simulations. We carry out numerical simulations with respect to the feeding velocity of the film, the pressure of the slot-die inlet, and the viscosity of the coating liquid. Based on the results, the coating was the most reliable when the pressure of the inlet was $5kgf/cm^2$, the viscosity was about 100 cps and the velocity was 20 m/min.

Cold Acoustic Tests for the Elucidation of the Gap of Optimal Damping Capacity of Baffled Injectors in Liquid Rocket Combustors (로켓연소기에서 분사기형 배플의 간극에 따른 감쇠특성 파악을 위한 상온음향시험)

  • Kim, Hong-Jip;Lee, Kwang-Jin;Choi, Hwan-Seok
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.35 no.8
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    • pp.720-725
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    • 2007
  • Cold acoustic tests have been performed to elucidate the effect of baffle gaps on the optimal damping characteristics in a liquid rocket combustor where coaxial injectors are installed. For several axial baffle lengths, an optimal acoustic damping capacitance has been achieved in a certain gap range. Cold acoustic tests for simulating fluid viscosity by changing the pressure in a model chamber have been done to study the main mechanism of optimal damping. Experimental data have shown that the optimal gap for high damping capacity exists mainly due to the viscosity near the gap of baffles. Therefore, axial baffle length can be reduced by using the optimal baffle gap, providing a possible solution of thermal cooling problems. Also, these optimum characteristics can be some guidelines for manufacturing and assembling injectors in full-scaled rocket combustors.

A study of drop spreading between moving solid plates (움직이는 고체판 사이에서 액적의 퍼짐에 관한 연구)

  • Kwon, Hyuk-Min;Kim, Ho-Young
    • Proceedings of the KSME Conference
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    • 2007.05b
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    • pp.2967-2970
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    • 2007
  • In a usual painting process, a liquid drop spreads on canvas by being dragged along a paintbrush. To obtain the fundamental understanding of the painting process from the mechanical point of view, we experimentally investigate various dynamic behavior of a liquid drop that spreads between moving solid plates. It is shown that three distinct types of drop spreading take place, i.e. shearing, spreading, and intact dragging, depending on the liquid viscosity and surface tension, the plate speed, and the wettability. We suggest a regime map based on the capillary number and the receding contact angle, which indicates the boundaries between different types of spreading behavior in a dimensionless space.

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Ionic Liquid/Styrene-Acrylonitrile Copolymer Nanofibers as Chemiresistor for Alcohol Vapours

  • Kim, Min-Jae;Kang, Eun-Soo;Park, Dong-Wha;Shim, Bong-Sup;Shim, Sang-Eun
    • Bulletin of the Korean Chemical Society
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    • v.33 no.9
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    • pp.2867-2872
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    • 2012
  • SAN/$BMIPF_6$ nanofibers were fabricated by an electrospinning process and used as chemiresistors for sensing alcohol vapours. A hydrophobic and air-stable ionic liquid, $BMIPF_6$, was used to impart electrical conductivity to insulating SAN nanofibers. The effects of $BMIPF_6$ addition on the morphology of the nanofibers were explained in terms of surface tension, viscosity and conductivity. After exposing the SAN/$BMIPF_6$ nanofibers collected on an interdigitated electrode to alcohol vapours (ethanol, 1-propanol and 1-butanol), the resistance of the nanofibers decreased due to adsorption of alcohol molecules. The electrospun SAN/$BMIPF_6$ nanofibers sensor exhibited good sensitivity and reproducibility.

Single-panel simulation on liquid crystal on silicon

  • Liao, Engle;Chiu, Jack;Peng, James
    • 한국정보디스플레이학회:학술대회논문집
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    • 2004.08a
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    • pp.939-942
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    • 2004
  • In this study, we report simulation results of single-panel LCOS (liquid crystal on silicon). Reflective LCOS microdisplays are widely used in various projection and near-eye application. For one panel system, liquid crystal response time is an important variable. The panel must switch fast enough to support the display of Field color sequential with high field rates. In order to have fast response and good contrast, a vertical alignment (VA) cell was used in this study. With suitable selection on LC parameters like temperature, viscosity, elastic constant and birefringence, it is possible to get response time of around 2ms from a 2.0 um-thick vertical alignment cell. This result also indicates an ease of production control on 2.0 um cells than 1.0 um cells.

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Development of Performance Test Apparatus and Design Program of Liquid-Phase Plate Heat Exchanger (액상 판형열교환기 성능실험장비 및 설계프로그램 개발)

  • Park, Sang-Il;Song, Young-Ho
    • Proceedings of the KSME Conference
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    • 2004.11a
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    • pp.1306-1311
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    • 2004
  • The performance test apparatus of liquid-phase plate heat exchanger was installed and the computer program for design was developed in this study. The detail temperature distribution of hot and cold fluids in each path of heat exchanger was calculated by numerical method and the correlation for the heat transfer coefficient was defined. The heat transfer coefficients were measured using the working fluids of water and glycerine to investigate the effect of fluid viscosity. The measured heat transfer coefficients were compared with the calculated values obtained from the computer program and it was shown that error of the calculated values was generally less than 5%.

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Rheological properties of some thermotropic liquid crystalline polymers

  • Fan, Yurun;Dai, Shaocong;Tanner, Roger I.
    • Korea-Australia Rheology Journal
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    • v.15 no.3
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    • pp.109-115
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    • 2003
  • Rheometry testing and the DSC measurement of five thermotropic liquid crystalline polymers (TLCP) have been carried out. The dynamic viscosities of the five TLCPs show a typical shear-thinning behaviour obeying the power-law with the power indices from 0.2 to 0.3. When these TLCPs are heated above the melting temperatures determined by the DSC measurements, the dynamic viscosities first rapidly decrease by 2~3 orders of magnitude then level off, finally increase gradually with the further increasing of temperature. The steady shearing exhibited the same behaviour as the dynamic shearing, but serious edge fracture of material slippage out of the plates occurred. The abnormal temperature dependence of the viscosities can be explained by the nematic-isotropic transition. By using the concept of activation energy, we propose a simple model which can fit the shear-thinning behaviour quite well and predict qualitatively correct temperature effects.