• The Journal of the Acoustical Society of Korea
• /
• v.23 no.1
• /
• pp.1-7
• /
• 2004

We developed SH-SAW sensors to detect protein molecules in liquid solutions applying a particular antibody thin film on the delay line of transverse SAW devices. The antibody investigated was human-immune-globulin G (HigG) to hold the antigens (anti-HigG) in the protein solution. We fabricated the sensor generating 100 MHz with the piezoelectric single crystal LiTaO₃. We measured the frequency change of the sensor by adding the anti-body concentration on SAM (self assembled monolayer) deposited on the Au layer. The sensor showed stable response to the mass loading effects of the anti-HigG molecules with the sensitivity up to 10.8 ng/ml/Hz at noise level 400 Hz below.

• Proceedings of the Korean Vacuum Society Conference
• /
• 2015.08a
• /
• pp.233-233
• /
• 2015

We report on a simple method for inducing physical and chemical property-gradient on nanoimprinted patterns by intensity-regulated plasma treatment under caved sample stage. As for the size gradient, a line pattern having a linewidth of 294.9 nm was etched to have gradually varying width from 277.4 nm to 147.9 nm. Modified pattern was proven to be adaptable to replica stamp for reversal patterning. To investigate the wettability gradient, imprinted nanopatterns were coated with fluoroalkylsilane to increase the hydrophobicity, and the surface was modified to have gradually varying wettability from hydrophobic to hydrophilic (contact angle was ${\sim}160^{\circ}$ to ${\sim}5^{\circ}$ on a single chip). This method is expected to be applicable to the selective adsorption of biological entities and hydrodynamic manipulation of liquid droplets for the pumpless microfluidics.

• Journal of Power System Engineering
• /
• v.9 no.2
• /
• pp.33-39
• /
• 2005

Experiments are performed to study the mixed convection flow and heat transfer in an inclined parallel plates with the upper part cooled and the lower part heated uniformly. The Reynolds number ranges from $4.0{\times}10^{-3}\;to\;6.2{\times}10^{-2}$, the angle of inclination, ${\theta}$, from 0 to 45 degree from the horizontal line, and Pr of the high viscosity fluid is 909. In this paper, the PIV(Particle image velocimetry) with TLC(Thermo-sensitive liquid crystal) tracers is used for visualizing and analysis. This method allows simultaneous measurement of velocity and temperature field at a given instant of time. Quantitative data of the temperature and velocity are obtained by applying the color-image processing to a visualized image, and neural network is applied to the color-to-temperature calibration. This paper describes the methods, and presents the quantitative visualization of mixed convection. From this study, it is found that the flow pattern can be classified into three patterns which are affected by Reynolds number and the angle of inclination.

• The Transactions of the Korean Institute of Power Electronics
• /
• v.11 no.5
• /
• pp.471-479
• /
• 2006

Automatic transfer equipments of manufacturing and process line trend toward big size as LCD glass is big size, heavy weight. The conventional stocker uses rotational motor and mechanical power converter device as travel axis of stocker crane and then frequent maintenances by complex structure and mechanical friction are required. Also it has problem to minimize the particle generation. To solve these problems, this paper verified the performance of permanent magnet(PM) excited transverse flux linear motor(TFLM) that is big power density per unit volume applied for travel axis of 7 generation stocker that is being big size, high power, long distance by the experiment based on proposed control algorithm, controller and power converter device.

• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.38 no.7
• /
• pp.619-624
• /
• 2014

The critical heat flux (CHF) on a heat transfer surface with nanostructures is known to be significantly better than that on flat surfaces. Several physical mechanisms have been proposed to explain this phenomenon. However, almost all studies conducted so far have been qualitative, and a generalized theory has not yet been established. In this study, we developed a quantitative mechanism for CHF enhancement on a surface with nanostructures, based on vapor recoil and surface adhesion forces. We focused on the increase in the length of the triple contact line owing to the formation of nanostructures and the adhesion force between them and the liquid.

• Food Science and Biotechnology
• /
• v.17 no.5
• /
• pp.976-982
• /
• 2008

The 10 species of marine green algae was collected from Jejudo(Island) in Korea. Methanolic and aqueous extracts were prepared and screened for inhibition activities against tumor cell growth. Of the tested samples, the sea staghorn (Codium fragile) aqueous extract (CFAE) showed the highest activity on CT-26 cell growth. Therefore, CFAE was selected for further experiments and the possibility to induce apoptosis by the CFAE was investigated. Flow cytometric analysis revealed that it dose-dependently increased apoptotic cells with hypodiploid DNA contents in CT-26 cell line. These results indicated that CFAE can suppress the growth of CT-26 cells through apoptosis. The CFAE decreased the protein expression of anti-apoptotic Bcl-xL and led to the activation of caspase-3 and -7. A crude polysaccharide was separated from CFAE and it mainly constituted with 61.2% galactose and 30.5% arabinose as analyzed by high performance liquid chromatography (HPLC).

• Journal of Plant Biotechnology
• /
• v.34 no.3
• /
• pp.181-187
• /
• 2007

Orostachys japonicus A. Berger is a Perennial herbaceous plant which has been traditionally used as an anti-inflammatory agent to treat hepatitis and as an anticancer agent. The objective of this study was 1) to establish and proliferate in vitro plant of O. japonicus 2) to induce indirect somatic embryogenesis from O. japonicus. General calli and embryogenic calli in all ranges of 2,4-D and BA combination, were induced and were best at 22% (embryogenic cell) in 5.0 mg/L 2,4-D and 0.5 mg/L BA combination. Embryogenic cell line was maintained by subculture at 2 week intervals and transferred to solid and liquid medium for embryo formation. In solid medium culture, globular and heart shaped embryos were observed in MS medium containing 5.0 mg/L 2,4-D and 0.5 mg/L BA combination. The number of embryos was 6.5 per 0.5 g cell, and then the immature embryos transferred to MS basal medium for embryo development. In a suspension culture of embryogenic cells, globular and heart shaped embryos were emerged in MS medium supplemented with 3.0 mg/L 2,4-D and 0.3 mg/L BA combination after 10 days of incubation. The embryo formation rate was about 33% by suspension culture. The ratio of embryo germination was 60.9%, on the other side, the root formation rate was 74.3% in 1/2 MS continuously.

• IE interfaces
• /
• v.15 no.4
• /
• pp.325-337
• /
• 2002

In this study we consider the problem of production planning of TFT-LCD(Thin Film Transistor - Liquid Crystal Display) production factory. Due to the complexities of the TFT-LCD production processes, it is difficult to schedule the production planning, and the study about automated scheduler is insufficient. In addition, the existing production method is a Push-System to raise the operation rate with expensive equipment, that has the problem to satisfy the due-date. This study presents an algorithm having a concept of Pull-System that satisfies the due-date and considers specialties of TFT-LCD production process. We make MPS(Master Production Schedule) according to the sales order, and present algorithms for scheduling about In/Out plan considering factory capacity, line balancing, material requirement, and inventory level of all Array, Cell, and Module processes. These algorithms are integrated as an automated production system, and we implement them in the actual TFT-LCD factory circumstance.

• International Journal of Precision Engineering and Manufacturing
• /
• v.4 no.2
• /
• pp.49-56
• /
• 2003

As semi-solid forging (SSF) is compared with conventional casting such as gravity die-casting and squeeze casting, the product without inner defects can be obtained from semi-solid forming and globular microstructure as well. Generally, SSF consists of reheating, forging, and ejecting processes. In the reheating process, the materials are heated up to the temperature between the solidus and liquidus line at which the materials exists in the form of liquid-solid mixture. The process variables such as reheating time, reheating temperature, reheating holding time, and induction heating power has large effect on the quality of the reheated billets. It is difficult to consider all the variables at the same time for predicting the quality. In this paper, Taguchi method, regression analysis and neural network were applied to analyze the relationship between processing conditions and solid fraction. A356 alloy was used for the present study, and the learning data were extracted from the reheating experiments. Results by neural network were in good agreement with those by experiment. Polynominal regression analysis was formulated using the test data from neural network. Optimum processing condition was calculated to minimize the grain size and solid fraction standard deviation or to maximize the specimen temperature average. Discussion is given about reheating process of row material and results are presented with regard to accurate process variables fur proper solid fraction, specimen temperature and grain size.

• International Journal of Precision Engineering and Manufacturing
• /
• v.8 no.4
• /
• pp.50-55
• /
• 2007

Stereolithography (SLA) is a technique using a laser beam to cure a photopolymer liquid resin with three-dimensional computer-aided design (CAD) data, The accuracy of the prototype, the build time, and the cured properties of the resins are controlled by the SLA process parameters such as the size of the laser beam, scan velocity, hatch spacing, and layer thickness, In particular, the size of the laser beam is the most important parameter in SLA, This study investigated the curing properties of photopolymers as a function of the laser beam size, The cure width and depth were measured either on a single cure line or at a single cure layer for various hatch spacings and laser beam sizes, The cure depth ranged from 0.23 to 0.34 mm and was directly proportional to the beam radius, whereas the cure width ranged from 0.42 to 1.07 mm and was inversely proportional to the beam radius, The resulting surface roughness ranged from 1.12 to $2.23{\mu}m$ for a ratio of hatch spacing to beam radius in the range 0.5-2.0 at a beam radius of 0.17 mm and a scan velocity of 125 mm/sec.