• 한국산학기술학회논문지
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• 제12권4호
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• pp.1999-2004
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• 2011

본 논문은 매트릭스 수지로 LCP(Liquid crystal polymer)를 사용하였으며, 기계적 특성 및 화학적 특성을 증대시키기 위해 주 첨가제로 synthetic graphite, expanded graphite와 보조 첨가제로는 carbon black을 사용하여, 함량 별로 복합소재를 제조하였다. 사출성형 전 CAE 프로그램으로 해석을 하였으며, 유동성과 섬유 배향을 예측 했다. 복합 소재는 전동식 사출기를 이용하여 ASTM 복합 시편으로 사출성형 하였으며, 시편을 four point probe 장치를 사용하여 전기전도도를 측정/비교 하였으며, 기계적 강도는 굴곡강도, 굴곡탄성률, 충격강도를 측정하였다. 첨가제가 증가할 수록 전기전도도는 증가하나 첨가제의 brittle한 특성으로 인해 기계적 강도는 감소하는 것을 확인 할 수 있었다.

• 한국전기전자재료학회논문지
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• 제32권4호
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• pp.276-280
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• 2019

In this study, we investigated the crystal defects and grain boundary properties in a ZZCCC ($ZnO-Zn_2BiVO_6-Co_3O_4-Cr_2O_3-CaCO_3$) varistor, with the liquid-phase sintering aid $Zn_2BiVO_6$ developed by our laboratory. The ZZCCC varistor sintered at $1,200^{\circ}C$ exhibited excellent nonlinear current-voltage characteristics (${\alpha}=63$), with oxygen vacancy ($V_o^*$ ; 0.35 eV) as a main defect, and an apparent activation energy of 1.1 eV with an electrically single grain boundary. Therefore, among the various additives to improve the electrical properties of ZnO varistors, if $Zn_2BiVO_6$ is used as a liquid phase sintering aid, it will be ideal to use Co for the oxygen vacancy and Ca for the electrically single grain boundary. This will allow the good properties of ZnO varistors to be maintained up to high sintering temperatures.

• FOCUS: LIFE SCIENCE
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• 제1호
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• pp.3.1-3.7
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• 2024

The article discusses the critical role of chromatography in the analysis and purification of proteins in biopharmaceuticals, emphasizing the importance of comprehensive characterization for ensuring their safety and efficacy. It highlights the use of Avantor® ACE® HPLC columns for the separation and purification of proteins, focusing on the analysis of intact proteins using reversed-phase liquid chromatography (RPLC) with fully porous particles. This article also details the application of different mobile phase additives, such as TFA and formic acid, and emphasizes the advantages of using type B ultra-pure silica-based columns for efficiency and peak shape in biomolecule analysis. Additionally, it addresses the challenges of analyzing intact proteins due to slow molecular diffusion and introduces the concept of solid-core (or superficially porous) particles, emphasizing their benefits over traditional porous particles for the analysis of therapeutic proteins. Furthermore, it discusses the development of Avantor® ACE® UltraCore BIO columns, specifically designed for the high-efficiency separation of large biomolecules, such as proteins, and demonstrates their effectiveness in achieving high-resolution separations, even for higher molecular weight proteins like monoclonal antibodies (mAbs). In addition, it underscores the complexity of analyzing and characterizing intact protein biopharmaceuticals, requiring a range of analytical techniques and the use of wide-pore stationary phases, operated at elevated temperatures and with relatively shallow gradients. It highlights the comprehensive range of options offered by Avantor® ACE® wide pore columns, including both fully porous and solid-core particles, bonded with a variety of complementary stationary phase chemistries to optimize selectivity during method development. The use of ultrapure and highly inert base silica is emphasized for enabling the use of lower concentrations of mobile phase modifiers without compromising analyte peak shape, particularly beneficial for LC-MS applications. Then the article concludes by emphasizing the significance of reversed-phase liquid chromatography and its compatibility with mass spectrometry as a valuable tool for the separation and analysis of intact proteins and their closely related variants in biopharmaceuticals.

• 전기학회논문지
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• 제56권9호
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• pp.1602-1608
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• 2007

The composites were fabricated, respectively, using 61[vol.%] SiC-39[vol.%] $TiB_2$ and using 61[vol.%] SiC-39[vol.%] $ZrB_2$ powders with the liquid forming additives of 12[wt%] $Al_2O_3+Y_2O_3$ by hot pressing annealing at $1650[^{\circ}C]$ for 4 hours. Reactions between SiC and transition metal $TiB_2$, $ZrB_2$ were not observed in this microstructure. The result of phase analysis of composites by XRD revealed SiC(6H, 3C), $TiB_2$, $ZrB_2$ and $YAG(Al_5Y_3O_{12})$ crystal phase on the Liquid-Phase-Sintered(LPS) $SiC-TiB_2$, and $SiC-ZrB_2$ composite. $\beta\rightarrow\alpha-SiC$ phase transformation was occurred on the $SiC-TiB_2$ and $SiC-ZrB_2$ composite. The relative density, the flexural strength and Young's modulus showed the highest value of 98.57[%], 249.42[MPa] and 91.64[GPa] in $SiC-ZrB_2$ composite at room temperature respectively. The electrical resistivity showed the lowest value of $7.96{\times}10^{-4}[\Omega{\cdot}cm]$ for $SiC-ZrB_2$ composite at $25[^{\circ}C]$. The electrical resistivity of the $SiC-TiB_2$ and $SiC-ZrB_2$ composite was all positive temperature coefficient resistance (PTCR) in the temperature ranges from $25[^{\circ}C]$ to $700[^{\circ}C]$. The resistance temperature coefficient of composite showed the lowest value of $1.319\times10^{-3}/[^{\circ}C]$ for $SiC-ZrB_2$ composite in the temperature ranges from $100[^{\circ}C]$ to $300[^{\circ}C]$ Compositional design and optimization of processing parameters are key factors for controlling and improving the properties of SiC-based electroconductive ceramic composites.

• Animal Bioscience
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• 제34권1호
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• pp.74-84
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• 2021

Objective: Feed additives that modify rumen fermentation can be used to prevent metabolic disturbances such as acidosis and optimize beef cattle production. The study evaluated the effects of liquid and powdered forms of polyclonal antibody preparation (PAP) against Streptococcus bovis and Fusobacterium necrophorum on rumen fermentation parameters in ruminally cannulated non-lactating dairy cows that were adapted or unadapted to a high concentrate diet. Methods: A double 3×3 Latin square design was used with three PAP treatments (control, powdered, and liquid PAP) and two adaptation protocols (adapted, unadapted; applied to the square). Adapted animals were transitioned for 2 weeks from an all-forage to an 80% concentrate diet, while unadapted animals were switched abruptly. Results: Interactions between sampling time and adaptation were observed; 12 h after feeding, the adapted group had lower ruminal pH and greater total short chain fatty acid concentrations than the unadapted group, while the opposite was observed after 24 h. Acetate:propionate ratio, molar proportion of butyrate and ammonia nitrogen concentration were generally greater in adapted than unadapted cattle up to 36 h after feeding. Adaptation promoted 3.5 times the number of Entodinium protozoa but copy numbers of Streptococcus bovis and Fibrobacter succinogens genes in rumen fluid were not affected. However, neither liquid nor powdered forms of PAP altered rumen acidosis variables in adapted or unadapted animals. Conclusion: Adaptation of cattle to highly fermentable carbohydrate diets promoted a more stable ruminal environment, but PAP was not effective in this study in which no animal experienced acute or sub-acute rumen acidosis.

• 펄프종이기술
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• 제44권6호
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• pp.58-69
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• 2012

As the meaning of dictionary terminology, scum refers to a layer of impurities that accumulates at the surface of a liquid. In papermaking process, scum indicates the floated solid waste generated by a flotation process during the primary wastewater treatment. In this study, different kinds of stocks and scums collected from newspaper, liner, tissue and fine paper were analysed in details. The purpose of this study was firstly to demonstrate the composition characteristics of different sources of scum, secondly the analysis of environmental hazardous materials, and thirdly the evaluation of reutilization ability of fibrous materials from collected scum. As mentioned the meaning of solid waste, scum was actually differ from the waste sludge in sources, compositions and recycling abilities. In the same manner of waste paper, the sludge which is generated within onsite of papermaking processes would be reused as a raw material. The general compositions of scum from waste water were mainly inorganic ash materials, fine fibre fractions, recycled fibre debries, and ink particles. If the scum is able to reuse as fibrous additives in papermaking process, it could contribute to the savings of running costs in both the subsidiaries of fibrous material and the solid waste treatment with even small quantity.

• 한국재료학회:학술대회논문집
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• 한국재료학회 2009년도 추계학술발표대회
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• pp.42.1-42.1
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• 2009

In recent years, it has been tried to develop the efficacy and bioactivity of Calcium Phosphate cements(CPC) as injectable bone substitute (IBS) by reinforcing them through varying the amount in its compositions and relative concentrations or adding other additives. In this study, the biocompatibility of are inforced Calcium Phosphate-Calcium Sulfate injectable bone substitute (IBS)containing poly ($\varepsilon$-caprolactone)PCL microspheres was evaluated which consisted of solution chitosan and Na-citrate as liquid phase and tetra calcium phosphate (TTCP), dicalciumphosphate anhydrous (DCPA) powder as the solid phase. The in vitrobiocompatibility of the IBS was done using MTT assay and Cellular adhesion and spreading studies. The in vitro experiments with simulated body fluid (SBF) confirmed the formation of apatite on sample surface after 7 and 14 days of incubation in SBF. SEM images for one cell morphologies showed that the cellular attachment was good. MG-63 cells were found to maintain their phenotype on samples and SEM micrograph confirmed that cellular attachment was well. In vitro cytotoxicity tests by an extract dilution method showed that the IBS was cytocompatible for fibroblast L-929.

• 한국근적외분광분석학회:학술대회논문집
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• 한국근적외분광분석학회 2001년도 NIR-2001
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• pp.3122-3122
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• 2001

Documented quality control plays a vital role I the production of technical “Depth filter” sheets used in industries such as Beverage and pharmaceutical. Depth filter sheets which can be up to several millimeters thick are stacker in plate and frame filter systems. They are the core of stainless steel filter systems which can be up to several meters high. FT-NIR Spectroscopy has many potential applications in the whole production line of filter sheets. Raw materials such as different types of cellulose pads, white powdery fillers (e.g. Kieelgur, Perlite) or liquid chemicals such as wet-strength agents we, with the help of NIR, easy to identify. NIR can also determine physical parameters such as particle size, essential for the filtration behavior. FT-NIR can be used for the quality parameters of the final product. Moisture and permeability can be determined, and with the help of the speed of this NIR method it is possible to correct possible faults quickly in the production process. Waste production can be minimized which is good for both the product profitability and the environment. Further tests have shown that it is also possible to use NIR on-line in the production area, to check the concentrations and the homogeneity of the paper suspension consisting of cellulose fibres, fillers and additives.

• 한국산업보건학회지
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• 제23권2호
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• pp.156-163
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• 2013

Objectives: Numerous poisonous substances are used in paint manufacture, but there are differences in the results of GHS classification between the Ministry of Labor(MOL) and the Ministry of Environment(MOE). Therefore, paint manufacturers suffer confusion as to how to classify a given chemical's risk and hazard level. This paper was designed to compare the classification results of chemicals by the MOL and the MOE and suggest a harmonization measure. Methods: After selecting 25 poisonous substances from among the organic solvents, pigments, and additives used in paint manufacturer, the GHS classification results by MOL and MOE were compared. Further the logic and classification of the GHS proposed by each Ministry was analyzed. Based on the derived results, a harmonization plan was proposed. Results: Based on the GHS classification of the poisonous substances, the concordance is 10.0-66.6 %, excluded flammable liquid. The GHS classifications differed based on the suggested building blocks, the sub-classification method used, the references(data sources), and subjective judgment of the experts from each Ministry. In order to pursue the harmonization plan, cooperation is demanded from the MOL and MOE.

• Geomechanics and Engineering
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• 제12권1호
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• pp.111-125
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• 2017

Swelling and shrinkage characteristics of expansive fine grained soil cause volumetric changes followed by distress and damage to the structures. Soil stabilization can be explained as the alteration of the soil properties by chemical, mechanical or any other means in order to enhance the engineering properties of the soil. Utilization of industrial wastes in soil stabilization is cost effective and environment friendly. This paper presents an experimental study on stabilization of expansive soil using industrial wastes, viz. fly ash and dolochar. The paper includes the evaluation of engineering properties like unconfined compressive strength and California bearing ratio (CBR) of expansive soil collected from Balasore district of Odisha stabilized with fly ash and dolochar in different proportions and to predict the influence of these additives on engineering properties and strength characteristics of expansive soil. Both fly ash and dolochar were found to increase the CBR and decrease many index properties such as liquid limit, plastic limit, plasticity index, swelling index and UCS, thus enhancing the strength parameters of expansive soil.