• Korean Management Science Review
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• v.18 no.2
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• pp.61-72
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• 2001

This paper presents a decision support system (DSS) for selecting the best delivery policy at an internet general shopping mall with its own distribution center and many outside enterprises linked up with the mall. The DSS provides the decision maker with the performance information of three delivery policies (individual delivery, collective delivery, mixed delivery) for the given service level, customer order pattern, direct/indirect delivery ratio, unit costs of various delivery modes, upper level of goods characteristic index for collective delivery poller, etc. Furthermore, the DSS allows the decision maker to perform the sensitivity analyses of three delivery policies for their major parameters and unit costs of delivery modes. The DSS is developed with AweSim simulation 1anguage and Visual Basic programming 1anguage.

• Korean Management Science Review
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• v.33 no.2
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• pp.117-131
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• 2016

This study introduces the concepts on the phase-shifting phenomenon of financial markets, which was firstly used in econophysics area and explains how the phase-shifting behavior is studied in the fields of business management and finance. Specifically, we explain how the phases of financial markets are extremely changed under some external conditions, do an extensive literature review, and carry out case studies focusing on the 3 major financial crisis events including the 87 October crash, 97 Asian financial crisis, and 2007 global financial crisis. We also empirically examine the phase-shifting behavior of the Korean ELW products that has a similar payoff structure to the KOSPI200 options.

• Journal of Animal Science and Technology
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• v.60 no.6
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• pp.15.1-15.10
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• 2018

Methane emission from the enteric fermentation of ruminant livestock is a main source of greenhouse gas (GHG) emission and a major concern for global warming. Methane emission is also associated with dietary energy lose; hence, reduce feed efficiency. Due to the negative environmental impacts, methane mitigation has come forward in last few decades. To date numerous efforts were made in order to reduce methane emission from ruminants. No table mitigation approaches are rumen manipulation, alteration of rumen fermentation, modification of rumen microbial biodiversity by different means and rarely by animal manipulations. However, a comprehensive exploration for a sustainable methane mitigation approach is still lacking. Dietary modification is directly linked to changes in the rumen fermentation pattern and types of end products. Studies showed that changing fermentation pattern is one of the most effective ways of methane abatement. Desirable dietary changes provide two fold benefits i.e. improve production and reduce GHG emissions. Therefore, the aim of this review is to discuss biology of methane emission from ruminants and its mitigation through dietary manipulation.

• The Journal of Korea Robotics Society
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• v.2 no.2
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• pp.191-195
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• 2007

Abstract MOCIE(Ministry of Commerce, Industry and Energy) handles 6 Projects for Intelligent Robot, whose budget is around 40 Million dollars per year. In this paper we have tried to analyze the state of robot technology of the projects. Each sub-projects has been divided according to the technological classification. Two major projects of Next Generation Growth Engine and 21C Frontier show different state each other. The former is focused on the product while the latter on the technology. Output of 21C Frontier should be linked to the Next Generation Growth Engine, otherwise, it will fail to advance. The project management handles only the quantitative performance such as business results, number of prototype, and number of patents and papers. Technological Capability is essential and it should be managed. This paper proposes efficient classification of robot technology and technology index.

• Journal of the Korean Regional Science Association
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• v.11 no.1
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• pp.93-111
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• 1995

This study investigated the nature of spatial concentration and dispersion of corporate control within an international system of decision-making centers. It introduces a simplified model of the global evolution of quaternary places. Linked to the national quaternary place model, the proposed model is useful for examinations involving real world situations associated with international corporations. This five stage model emphasizes the importance of the organizational structure of large corporations, industrial networks and the development of information technology. It suggests the dispersion of international quaternary places along with the diversification of corporate control linkages among quaternary centers. A case study for 1974-1991 uses information statistics to identify the current stage of the international quaternary system. The result is in general agreement with major elements of the stage model. This theoretical concept and empirical research contribute to the expansion of quaternary place theory to the global scale in particular, and to the development of location analysis in general.

• Korean Journal of Geomatics
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• v.2 no.2
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• pp.115-122
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• 2002

Since geographic information systems (GIS) began to emerge as an effective spatial information processing technology, there also has been growing interest in integrated use of GIS with other decision support systems. As various spatial-related problems such as urban development planning and natural resource management require more analytical and interpretive solutions, it is viewed that the supportive role of GIS to complement or reinforce the counterpart decision tools will be increased. This study examines the major situations that have needed the integration methodologies in the past decade to derive research trends relating to this integration agenda and, hence, to elicit the possible underlying principles from those experiences. According to the kinds of decision tools linked with GIS, alternative methodologies and viewpoints are categorized and compared.

• Molecules and Cells
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• v.38 no.4
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• pp.285-296
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• 2015

Oxidative stress has been linked to the pathogenesis of diabetic nephropathy, the complication of diabetes in the kidney. NADPH oxidases of the Nox family, and in particular the homologue Nox4, are a major source of reactive oxygen species in the diabetic kidney and are critical mediators of redox signaling in glomerular and tubulointerstitial cells exposed to the diabetic milieu. Here, we present an overview of the current knowledge related to the understanding of the role of Nox enzymes in the processes that control mesangial cell, podocyte and tubulointerstitial cell injury induced by hyperglycemia and other predominant factors enhanced in the diabetic milieu, including the renin-angiotensin system and transforming growth factor-${\beta}$. The nature of the upstream modulators of Nox enzymes as well as the downstream targets of the Nox NADPH oxidases implicated in the propagation of the redox processes that alter renal biology in diabetes will be highlighted.

• Journal of the Korean Ceramic Society
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• v.31 no.1
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• pp.47-54
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• 1994

The fundamental studies for exploit natural resources was investigated on Uljin pottery stones that estimated the amount of mineral deposits at 350 million tons. The results obtained are as follows; In the chemical composition of Uljin pottery stones the amount of Al2O3 are a little compared with other pottery stones and that of Na2O and K2O are a large. Fe2O3 content is lower than 0.3 wt%, thus whiteness of its is 83. The major minerals composition of Uljin pottery stones are quartz and feldspar mineral. The refractoriness (SK) of its is 14. Lattice constants of quartz in Uljin pottery stones are 4.8865 $\AA$ in a-axis and 5.3852 $\AA$ in c-axis. Lattice constants were expanded by HCl treatment and sintering. Microstructures of Uljin pottery stones are linked up with the crystal particles under 10 microns in size.

• Journal of Korean Institute of Industrial Engineers
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• v.22 no.3
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• pp.427-440
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• 1996

Constraint networks are a major approach to knowledge representation in Concurrent Engineering (CE) systems. The networks model various factors in CE as constraints linked by shared variables. Many systems have been developed to assist constraint network processing. While these systems can be useful, their underlying assumption that a solution must simultaneously satisfy all the constraints is often unrealistic and hard to achieve. Proposed in this paper is a hierarchical representation of constraint networks using priorities, namely Prioritized Constraint Network (PCN). A mechanism to propagate priorities is developed, and a new satisfiability definition taking into account the priorities is described. Strength of constraint supporters can be derived from the propagated priorities. Several properties useful for investigating PCN's and finding effective solving strategies ore developed.

• BMB Reports
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• v.41 no.12
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• pp.827-832
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• 2008

Many age-dependent neurodegenerative diseases are associated with the accumulation of abnormally folded proteins within neurons. One of the major proteolytic pathways in the cell is the autophagy pathway, which targets cytoplasmic contents and organelles to the lysosomes for bulk degradation under various physiological and stressful conditions. Although the importance of autophagy in cellular physiology is well appreciated, its precise roles in neurodegeneration remain largely unclear. Recent studies indicate that components of the endosomal sorting complex required for transport (ESCRT) are important in the autophagy pathway. Reduced activity of some ESCRT subunits leads to the accumulation of autophagosomes and failure to clear intracellular protein aggregates. Interestingly, rare mutations in CHMP2B, an ESCRT-III subunit, are associated with frontotemporal dementia linked to chromosome 3 (FTD3). Mutant CHMP2B proteins seem to disrupt the fusion of autophagosomes and lysosomes in cell culture models. These findings suggest a potential mechanism for the pathogenesis of FTD3 and possibly other neurodegenerative diseases as well.