• Journal of the Korean Home Economics Association
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• v.23 no.1
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• pp.71-85
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• 1985

The study attempts to explore factors which affect life satisfaction of the elderly, and thereby to identify the most efficient strategy to enhance their happiness and satisfaction with life by means of a family support system. Previous research suggests that the family is the main origin from which emotional and ecionomic satisfacton of the aged evolves, and satisfaction is facilitated by societal assistance for the family to financially support old persons. These theoretical antecedents are incorporated into a causal model for empirical verificatio. To this end, interviews were conducted in Seoul with 300 individuals who are 60 years old or over. The major findings of this study support the theoretical assertions of previous studies. They are summarized as follows : 1. Family solidarity is highly correlated with life satisfaction of the elderly. 2. Family solidarity is raised by the intensity of their social association, satisfaction with housing, and financial resources. 3. Eduation, income and marital status as exogenous variables do not directly affect life satisfaction and family solidarity, despite their strong overall correlation. Casual effects of each variable are linked to family solidarity and then to life satisfaction through a family support system for the elderly.

• Proceedings of the Korean Society For Composite Materials Conference
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• 2003.10a
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• pp.111-114
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• 2003

Thermosets are highly cross-linked polymers with a three-dimensional molecular structure. The network structure gives rise to mechanical properties, however, one major drawback of thermosets, which also results from their network structure, is their poor resistance to impact and to crack initiation. In this study, to solve this problem, the reactive thermoplastics such as amine terminated polyetherimide (ATPEI), ATPEI-CTBN-ATPEI(ABA) triblock copolymer, CTBN-ATPEI(AB) diblock copolymer, and carboxyl group modified ATPEI was synthesized, after that blended with epoxy resin, and the carbon fiber reinforced composites were fabricated. The impact load, energy, and delamination were investigated by using drop weight impact test and C-scan test. As a results, the ABA/epoxy blend system showed good impact properties.

• Biomolecules & Therapeutics
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• v.9 no.3
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• pp.162-166
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• 2001

Helicobacter pylori is a major cause of gastric-associated diseases. In our previous study, the Adhesin/CTXA2B was expressed as insoluble recombinant chimeric protein derived from the H. pylori adhesin genetically coupled to CTXA2B subunit in Escherichia coli. Since it is very important to optimize IPTG concentration, culture temperature and composition of medium to maximize cell growth and productivity, these conditional growth factors were determined for increasing the productivity of the expressed Adhesin/CTXA2B chimeric protein in Escherichia coli JM101 carrying pTEDhpa/ctxa2b. Our data demonstrate that optimal medium for increased production of chimeric protein was a YCP/Glu medium composed of 2% yeast extract, 1% casamino acid, phosphate solution [0.3% $KH_2P0_4$, 0.4% $Na_2HP0_4$, 0.25% ($NH_4)_2HPO_4$], and 0.5% glucose. In addition, optimal concentration of IPTG was 1 mM and culture temperature, $37^{\circ}C$.

• Molecules and Cells
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• v.25 no.2
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• pp.149-157
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• 2008

Dopamine is a major neurotransmitter in the mammalian central nervous system (CNS) that regulates neuroendocrine functions, locomotor activity, cognition and emotion. The dopamine system has been extensively studied because dysfunction of this system is linked to various pathological conditions including Parkinson's disease, schizophrenia, Tourette's syndrome, and drug addiction. Accordingly, intense efforts to delineate the full complement of signaling pathways mediated by individual receptor subtypes have been pursued. Dopamine D1-like receptors are of particular interest because they are the most abundant dopamine receptors in CNS. Recent work suggests that dopamine signaling could be regulated via dopamine receptor interacting proteins (DRIPs). Unraveling these DRIPs involved in the dopamine system may provide a better understanding of the mechanisms underlying CNS disorders related to dopamine system dysfunction and may help identify novel therapeutic targets.

• BMB Reports
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• v.49 no.10
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• pp.536-541
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• 2016

The prevalence of obesity and type 2 diabetes, two closely linked metabolic disorders, is increasing worldwide. Over the past decade, the connection between these disorders and the microbiota of the gut has become a major focus of biomedical research, with recent studies demonstrating the fundamental role of intestinal microbiota in the regulation and pathogenesis of metabolic disorders. Because of the complexity of the microbiota community, however, the underlying molecular mechanisms by which the gut microbiota is associated with metabolic disorders remain poorly understood. In this review, we summarize recent studies that investigate the role of the microbiota in both human subjects and animal models of disease and discuss relevant therapeutic targets for future research.

• Proceedings of the Korea Air Pollution Research Association Conference
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• 2003.11a
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• pp.512-513
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• 2003

Human activities have become a major factor that significantly changes the global environment. Mankind has increasingly used land, water, minerals and other natural resources since the beginning of industrialization, and future growth in the population and economy is thought to further enhance the impact upon the Earth. The global climate, biogeochemical process and natural ecosystems are closely linked with one another, and changes in any one of these systems may effect the others, which could result in consequences detrimental to humans and other living organisms on the Earth.(omitted)

• Korean Management Science Review
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• v.26 no.2
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• pp.37-59
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• 2009

Electronic brainstorming (EBS) to improve the process and outcomes of group decision making is an artifact of Information Systems legacy. Despite three decades of research with EBS in an effort to become a key resource of organizational performance, its performance when compared to that of nominal is inconclusive because of the recent debate over its usefulness in terms of productivity. Subsequent researchers have directed our attention to the re-examination of cognitive stimulation, which is considered the major benefit in computer-based idea generation, to explain the performance singularity in computer-based groups. While both cognitive and motivational factors that moderate and mediate the group-interaction process remain unexplored, individual differences that are tightly linked to creative behavior have been largely ignored to account for the discrepancy in performance. Since simulations have been widely used in situations where an outcome does not meet the assumptions, the notion of a group simulator and detailed simulation mechanisms are introduced to examine the potential effects of individual differences on the performance of computer-based idea generation groups. In addition, two prior studies that empirically explored cognitive mechanisms with the group simulator are showcased along with six propositions to initiate future research.

• Journal of Korean Library and Information Science Society
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• v.18
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• pp.217-243
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• 1991

Authority control enables us to retrieve information accurately by coordination and cross reference of headings. It is considered that authority control is needed in machine readable catalogs as well as in conventional catalogs. Taylor, Maxwell and Frost divided automated authority control systems into major vendor and network systems then available into two groups. The first group was defined as a system that processes a library's machine readable catalogs on the tape against an automated authority file. The second group offers an online access to catalogs and authority records. This group was further subdivided into linked or integrated systems and unlinked systems. If authority work is shared with many libraries the costs can be considerably reduced and the quality of catalog data base can be controled by standardization of headings used in participating libraries. The NACO is a project for sharing of authority records started in 1977 by L.C. And LSP furthers the ability to share authority records. A project as the NACO is necessary not only in America but also in the other countries The responsible organizations for national bibliographies of the countries must take much interest in these matters.

• Journal of Microbiology and Biotechnology
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• v.17 no.4
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• pp.695-700
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• 2007

The cycloinulooligosaccharide fructanotransferase (CFTase) gene (cft) from Paenibacillus macerans (GenBank access code AF222787) was expressed on the cell surface of Saccharomyces cerevisiae by fusing with Aga2p linked to the membrane-anchored protein Aga1p. The surface display of CFTase was confirmed by immunofluorescence microscopy and enzymatic assay. The optimized reaction conditions of surface-displayed CFTase were as follows; pH, 8.0; temperature, $50^{\circ}C$; enzyme amount, 30 milliunit; substrate concentration, 5%; inulin source, Jerusalem artichoke. As a result of the reaction with inulin, cycloinulohexaose was produced as a major product along with cycloinuloheptaose and cycloinulooctaose as minor products.

• Journal of Microbiology and Biotechnology
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• v.23 no.6
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• pp.878-884
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• 2013

Salmonella is a major foodborne pathogen that causes a variety of human diseases. Development of ligands directly and specifically binding to the Salmonella will be crucial for the rapid detection of, and thus for efficient protection from, the virulent bacteria. In this study, we identified a RNA aptamer-based ligand that can specifically recognize Salmonella Typhimurium through SELEX technology. To this end, we isolated and characterized an RNase-resistant RNA aptamer that bound to the OmpC protein of Salmonella Typhimurium with high specificity and affinity ($K_d$ ~ 20 nM). Of note, the selected aptamer was found to specifically bind to Salmonella Typhimurium, but neither to Gram-positive bacteria (Staphylococcus aureus) nor to other Gram-negative bacteria (Escherichia coli O157:H7). This was evinced by aptamer-immobilized ELISA and aptamer-linked precipitation experiments. This Salmonella species-specific aptamer could be useful as a diagnostic ligand against pathogen-caused foodborne sickness.