• Title/Summary/Keyword: Linkage technology

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Linkage Disequilibrium and Gene Expression Analyses of IGF2 Gene in Korean Native Pigs (재래돼지를 이용한 IGF2 유전자의 연관불균형과 유전자발현양상에 대한 분석)

  • Li, Song-Lan;Li, Xiaoping;Choi, Bong-Hwan;Lee, Cheol-Koo;Cho, Byung-Wook;Kim, Jong-Joo;Kim, Kwan-Suk
    • Journal of Animal Science and Technology
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    • v.51 no.1
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    • pp.9-14
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    • 2009
  • Insulin-like growth factor 2 (IGF2) is the first identified imprinted gene, which is paternally expressed in multiple mammalian species. A paternally expressed QTL for muscle growth and backfat thickness (BFT) has previously been identified near the IGF2 locus on the distal tip of pig chromosome 2 (SSC2p). Therefore the IGF2 gene is considered an economically important candidate gene for pig industry. Herein, this study explored genetic variation of IGF2 for in3-G3072A, in7-G162C and a new SNP in intron7 (C1589T) in Korean native pig (KNP) and commercial pig breeds, and detected their linkage disequilibrium within these breeds. Furthermore we investigated the effect of in3-G3072A on IGF2 gene expression in post-natal muscle and backfat tissues. The real-time quantitative PCR results showed that animals inherited allele G from a KNP sire had significant higher IGF2 gene expression in backfat tissue than those inherited allele A from a Yorkshire sire, however opposite situation in muscle. These results demonstrated the allele 3072G is associated with a higher IGF2 gene expression in fat tissues, but low gene expression in muscle tissues when compared with the 3072A allele. These results suggest that KNP with lower muscle mass and higher fat deposition might be associated with a higher frequency of the 3072G allele, and selecting KNP based on IGF2 genotypes could result in an economic benefit to KNP producers.

An Input/Output analysis of the transportation industry for evaluating its economical contribution and ripple effect - Forecasting the I-O table in 2003~2009 - (교통부문의 경제적 기여도 및 파급효과 도출을 위한 산업연관분석 연구 - 2003~2009년 산업연관표 중심으로 -)

  • Lim, Siyeong;Kim, Seok;Oh, Eun-ho;Lee, Kyo Sun
    • Korean Journal of Construction Engineering and Management
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    • v.16 no.4
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    • pp.12-20
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    • 2015
  • Construction industry has played a pivotal role in the national economy, but the crisis situation of a construction industry has been worse due to the lack of recognition of the contribution of a construction industry. In particular, the transport sector is responsible for a critical function in the movement of humans and material resources, and has a profound impact on national competitiveness and the peoples' welfare, which requires quantitative analysis. In this study, economic contribution and impact of the transportation sector are measured based on the input-output model. Road and railway facilities account for 1.03% and 0.165% of the total industry respectively, and consist of a final demand and total output. Although value-added inducing effect is small, production inducing effect and backward linkage effect has been high. The results in this study will be used as the basic information for validity of investment and policy decisions.

Extraction of Glycosaminoglycan from Sea Hare, Aplysia kurodai, and Its Functional Properties 2. Structural Properties of Purified Glycosaminoglycan (군소(Aplysia kurodai)에 분포하는 글루코사미노글리칸의 추출과 기능특성 2. 글루코사미노글리칸의 구조 특성)

  • Yoon, Bo-Yeong;Choi, Byeong-Dai;Bae, Dong-Won;Choi, Yeung-Joon
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.39 no.11
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    • pp.1647-1653
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    • 2010
  • Glycosaminoglycan (GAG) was purified from polysaccharide extracted from sea hare muscle on DEAE-Sepharose column and investigated for the functional groups, distribution of sugars, composition of disaccharide and structure of GAG. Purified GAG was composed of disaccharide above 55% of total sugar. Purified GAG showed amide I peak in 1648/cm and C-O stretch peak as properties of carbohydrate, amino acid peak in 1457/cm, and peak in 866/cm as properties of monosaccharide by FT-IR. Fucose, N-acetylgalactosamine, N-acetylglucosamine, glucose, galactose, mannose and xylose were found in MALDI-TOF MS/MS spectra of hydrolysates by chondroitin sulfate ABC lyase and heparanase I. Purified GAG was expected to be heparan sulfate including N-acetylgalactosamine and N-acetylglucosamine above 70% of total sugar. The structure of GAG was supposed as GlyUA(2S)-GlcNS and GlyUA-GlcNS(6S) with O-linkage on protein core.

Analysis of Assessment Indicator on Priorities for Budget Allocation of the National R&D Program (국가연구개발사업 예산배분을 위한 우선순위 판단지표 분석)

  • Ahn, Seung-Ku;Kim, Eun-Sil;Cho, Hyun-Jeong
    • Journal of Korea Technology Innovation Society
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    • v.14 no.4
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    • pp.889-914
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    • 2011
  • This paper is to review assessment indicator on priorities for budget allocation of the national R&D program. In priority setting of programs for the budget allocation process of the national R&D program using the Analytical Hierarchy Process (AHP), the survey result on the major influencing factors is as follows: the significance of components of evaluation for the priority of the national R&D programs in budget allocation was as following order: "accomplishment and ripple effect of the project," "basis and driving force for the promotion of project," "feasibility of project goals," and the "possibility of overlapping and linkage among projects". The importance of the final evaluation indicator was as following order: "clarity and possibility for accomplishment of business objectives," "ripple effects in terms of science and technology", "ripple effects in terms of the economy and overall society" and "appropriate correspondence with mid- to long-term plans" (the importance for these four indicators was over 10%) while the importance of "overlapping" and "appropriateness of budget size" indicators which fell below 5% were considered to be relatively less important. there is a need for a clear criteria and conceptions of evaluation indicators for budget allocation of national R&D programs.

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A Study on the Applicability of IoT for Container Terminal (컨테이너 터미널의 사물인터넷(IoT) 적용가능성에 관한 연구)

  • Jeon, Sang-Hyeon;Kang, Dal-Won;Min, Se-Hong;Kim, Si-Hyun
    • Journal of Korea Port Economic Association
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    • v.36 no.2
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    • pp.1-18
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    • 2020
  • The Internet of things (IoT) has been applied to a variety of industrial uses such as public service sectors, medical industries, automotive industries, and so on. Led by smart cities, this is typical. However, from a logistics perspective, the level of application is insufficient. This study examines the applicability of IoT-related technology in a container terminal, an object of the present invention, to derive an applicable plan. Analytic network process (ANP) analysis reveals the following results for IoT applications in container terminals: operating systems (26.7%), safety/environmental/security systems (26.4%), equipment maintenance systems (25.3%), and facility maintenance systems (21.6 %). The second ANP analysis reveals the following results: Economy (40.2%), productivity (21.1%), service level (19.5%), and utilizing technology level (19.2%). The application or standard of evaluation is important when applying IoT technology to container terminals; however, it is not concentrated in a certain area. It is desirable to build each container system with linkage and efficiency from a macroscopic view.

Linkage Base of Geo-based Processing Service and Open PaaS Cloud (오픈소스 PaaS 클라우드와 공간정보 처리서비스 연계 기초)

  • KIM, Kwang-Seob;LEE, KI-Won
    • Journal of the Korean Association of Geographic Information Studies
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    • v.20 no.4
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    • pp.24-38
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    • 2017
  • The awareness and demand for technological elements in the field of cloud computing and their application models have increased. Cloud-based service information systems are being expanded for use in many applications. Advancements in information technology are directly related to spatial information. PaaS is an important platform for implementing a substantial cloud ecosystem to develop geo-based application services. For this reason, it is necessary to analyze the PaaS cloud technology prior to the development of SaaS. The PaaS cloud supports sharing of related extensions, database operations and management, and application development and deployment. The development of geo-spatial information systems or services based on PaaS in ranging the domestic and overseas range is in the initial stages of both research and application. In this study, state-of-the-art cloud computing is reviewed and a conceptual design for geo-based applications is presented. The proposed model is based on container methods, which are the core elements of PaaS cloud technology based on open source. It is thought that these technologies contribute to the applicability and scalability of the geo-spatial information industry that addresses cloud computing. It is expected that the results of this study will provide a technological base for practical service implementation and experimentation for geo-based applications.

Proposal for a Custody and Federated Service Model for the Decentralized Identity (분산 ID 보관 및 연계 서비스 모델 제안)

  • Yeo, Kiho;Park, Keundug;Youm, Heung Youl
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.30 no.3
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    • pp.513-525
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    • 2020
  • Until today, the personal information of subjects has been centralized in many companies or institutions. However, in recent days, the paradigm has gradually changed in the direction that subjects control their personal information and persue their self-sovereignty. Globally, individual data sovereignty is strengthened by the European Union's General Data Protection Regulation(GDPR) and the US California Consumer Privacy Act(CCPA). In Korea, a few alliances consist of various companies are creating technology research and service application cases for decentralized ID service model. In this paper, the current decentralized ID service model and its limitations are studied, and a improved decentralized ID service model that can solve them is proposed. The proposed model has a function of securely storing decentralized ID to the third party and a linkage function that can be interoperated even if different decentralized ID services are generated. In addition, a more secure and convenient model by identifying the security threats of the proposed model and deriving the security requirements, is proposed. It is expected that the decentralized ID technology will be applied not only to the proof of people but also to the device ID authentication management of the IoT in the future.

A Study on the Government's R&D Budgeting Evaluation System in Korea (과학기술혁신체제 하에서의 국가연구개발 평가 시스템 개선에 관한 연구 : 연구개발 예산평가 시스템을 중심으로)

  • Bark, Pyeng-Mu;Lee, Ki-Jong
    • Journal of Korea Technology Innovation Society
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    • v.12 no.4
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    • pp.819-839
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    • 2009
  • Proposed increases to the government's R&D budget should be discussed based on merits of meeting efficiency and effectiveness criteria. The evaluation of the national R&D budget and related programs are performed in two areas: a system of R&D budget coordination and allocation, and a system of R&D program performance. This paper mainly focuses on the operational areas of R&D budget evaluation system with a focus on their impact to efficiency and effectiveness. The core view point for a R&D budget evaluation system involves two directions: Firstly, to detail the relationships between the later stage (ex. post) activities such as, program survey, analysis, and program performance evaluation, with the budget evaluation. Secondly, to critically oversee all R&D coordination procedures with a different perspective. Budgeting is generally known as a serial process of policy making, planning and executing. It is highly desirable for the budget to be allocated to, and spent by, specific programs as planned, and that each plan be aligned with a specific policy. As such, a strong relevance between the program structure and budget code system is integral to successful execution. It should be performed using a decision making system which closely examines the link between policy and budget. It is also recommended that systematic relationships be maintained among budget coordination and allocation, performance evaluations of policy and program levels, and program survey and analysis system, and that their operational schedule should be reviewed comprehensively as a one integrated system. The National Science and Technology Council is expected to play a major and practical role as the center of policy planning and should be supported by the objective and unbiased system which covers overall process from policy making to program evaluation. Finally, increased utilization of contents, timely program survey and analysis, and accurate of activity scheduling of budget coordination and allocation, and diligent program performance evaluation all contribute towards a more efficient and effective overall evaluation system.

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Effects of the water level reduction and the flow distribution according to change of the side weir location in detention reservoir (홍수조절지 횡월류위어의 위치 변화에 따른 수위 저감 및 유량 분담 효과)

  • Seong, Hoje;Park, Inhwan;Rhee, Dong Sop
    • Journal of Korea Water Resources Association
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    • v.51 no.7
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    • pp.555-564
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    • 2018
  • The detention reservoir is a hydraulic structure that constructs a levee on the inland of river and sets up side weir in a section of the levee, and this facility stores a part of the flood volume in case of a flood event over a certain scale. In order to optimize the operation of detention reservoir, it is necessary to review the linkage with existing facilities in the river. In this study, the effect of water level reduction and the flow distribution was analyzed according to the location of the side weir in the detention reservoir considering the run-of-the-river gate. Two radial gates were installed in the experimental channel, and the water level in channel and the overflow of weir were measured by moving the location of the side weir upstream from the gate. As a results of experiment, it was confirmed that the water level reduction is more remarkable as the location of the side weir was closer to the gate, and the effect of flow distribution is not greatly changed. When two or more side weirs were operated, it is confirmed that the sufficient storage space was secured and the water level reduction effect with the location of the side weir is not large. In addition, the water level reduction rate according to the location of the side weir was estimated by empirical formula and it is provided as basic data that can be used in the planning of the detention reservoir.

Development of Smart Livestock Disease Control Strategies and Policy Priorities (스마트 가축방역 추진전략 및 정책 우선순위)

  • Lee, Jeongyoung;Ko, Sang Min;Kim, Meenjong;Ji, Yong Gu;Kim, Hoontae
    • The Journal of Society for e-Business Studies
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    • v.23 no.4
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    • pp.109-126
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    • 2018
  • With massive and dense production, the livestock industry is rapidly moving into a large-scale, capital-intensive industry especially in swine, poultry, and ducks. However, livestock epidemics can pose a serious threat to the livestock industry and the lives of the people. The government has established and operates the National Animal Protection and Prevention System (KAHIS) since 2013 in order to control the threat, in accordance with the five stages. The digitalized data and information are excellent in ease of management, but it is also pointed out that it is difficult to take countermeasures through linkage with the data in an emergency situation. Recently, the technology of the fourth industrial revolution such as Internet of Things (IoT), Big Data, Artificial intelligence (AI) has been rapidly implemented to the livestock industry, which makes smart livestock disease control system possible. Therefore, this study investigated the domestic and overseas cases which apply 4th Industrial Revolution technology in the industry, and derived 13 possible candidate tasks in the near future. In order to ascertain the priority of policy formulation, we surveyed the expert groups and examined the priority of each of the five stages of the prevention and the priority of each stage. The results of this study are expected to contribute to the establishment of policies for the advancement of smart livestock disease control research and livestock protection.