• Herbal Formula Science
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• v.26 no.1
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• pp.81-102
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• 2018

Objectives : I analysed daehwangmokdan-tang's compatibility principle by the system of chief, deputy, assistant, and envoy and investigated pharmacological activities by categorizing with chemical components, molecular level, cellular level, animal level and human level based on Korean and Chinese studies for this formula. Methods : Daehwangmokdan-tang's compatibiltity principle was examined by the system of chief, deputy, assistant, and envoy. I looked into studies that presented in Korea from 1956 to 2016 about daehwangmokdan-tang through KOREA INSTITUTE OF ORIENTAL MEDICINE, Korean medicine information system (OASIS) and in Chinese for 20 years about daehwangmokdan-tang through China National Knowledge Infrastructure, CNKI. Then classify into chemical components, molecular level, cellular level, animal level and human level to analyse. Results : According to the system of chief, deputy, assistant, and envoy, chief herb is Rhei Radix et Rhizoma and Moutan Cortex, deputy herb is Natrii Sulfas and Persicae Semen, assistant and envoy herbs are Trichosanthis Semen. The amount of extraction of paeonol, total anthraquinone, and conjugated anthraquinone from daehwangmokdan-tang with the formulation of the system of chief, deputy, assistant, and envoy was the highest, and in the formulation of chief herb and deputy herb, the extraction amount of paeonol and conjugated anthraquinone was the lowest. With other formulations, the amount of extraction of total anthraquinone and conjugated anthraquinone was improved, although the degree was different. In particular, when it is blended with Persicae Semen as a deputy herb, the extraction amount of total anthraquinone and conjugated anthraquinone of Rhei Radix et Rhizoma as a chief herb is greatly increased, and the extraction amount of paeonol is rather different, but it is lowered. It was found that the amount of Mg Ca K Na in daehwangmokdan-tang was the highest. Pharmacological activities can be detected in inflammatory mediators and enzymes for molecular level. For cellular level, it can be determined in lipopolysaccharide (LPS)-stimulated RAW 264.7 cell line. In mouse and rats for animal level and human level, in inflammatory diseases (acute appendicitis, acute pancreatitis, acute cholecystitis, acute abdominal disease, ect.), pharmacological activities was caught. Conclusions : From the above results, daehwangmokdan-tang is composed in line with the system of chief, deputy, assistant, and envoy, suggesting that there is certain rationality and scientific. Pharmacological activities of daehwangmokdan-tang are effective to anti-inflammation, improvement of sepsis, analgesic, muscle relaxation, and improvement of intestinal flora and its metabolites. Daehwangmokdan-tang is consistent with the action of diuresis and anti-inflammation in terms of the content of elements, suggesting that there is action of purging fire and removing blood stasis, defecation detoxification, cooling blood and clearing heat and activating blood and dispersing stasis.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.44 no.2 s.314
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• pp.144-152
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• 2007

We propose a 3D modeling method for surface inspection of non-linear moving object. The laser lines reflect the surface curvature. We can acquire 3D surface information by analyzing projected laser lines on object. ill this paper, we use multi-line laser to make use of robust of single stripe method and high speed of single frame. Binarization and channel edge extraction method were used for robust laser line extraction. A new labeling method was used for laser line labeling. We acquired sink information between each 3D reconstructed frame by feature point matching, and registered each frame to one whole image. We verified the superiority of proposed method by applying it to container damage inspection system.

• Proceedings of the KSRS Conference
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• 2004.10a
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• pp.344-346
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• 2004

IKONOS 1m satellite imagery is particularly well suited for 3-D feature extraction and 1 :5,000 scale topographic mapping. Because the image line and sample calculated by given RPCs have the error of more than 11m, in order to be able to perform feature extraction and topographic mapping, rational polynomial coefficients(RPCs) camera model that are derived from the very complex IKONOS sensor model to describe the object-image geometry must be refined by several Ground Control Points(GCPs). This paper presents a quantitative evaluation of the geometric accuracy that can be achieved with IKONOS imagery by refining the offset and scaling factors of RPCs using several GCPs. If only two GCPs are available, the offsets and scale factors of image line and sample are updated. If we have more than three GCPs, four parameters of the offsets and scale factors of image line and sample are refined first, and then six parameters of the offsets and scale factors of latitude, longitude and height are updated. The stereo images acquired by IKONOS satellite are tested using six ground points. First, the RPCs model was refined using 2 GCPs and 4 check points acquired by GPS. The results from IKONOS stereo images are reported and these show that the RMSE of check point acquired from left images and right are 1.021m and 1.447m. And then we update the RPCs model using 4 GCPs and 2 check points. The RMSE of geometric accuracy is 0.621 m in left image and 0.816m in right image.

• Journal of the Korean Institute of Telematics and Electronics
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• v.26 no.1
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• pp.29-37
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• 1989

This paper presents an application of the extended DP matching method to the on-line recognition of cursive Hangeul (Korean characters). We decrease the number of matching's objects by performing rough classification matching which makes the best use of features in the first and the last segment of Hangeul. By adding the extraction function of the basic character patterns to DP matching method, we try to calculate precisely the difference among Hangeul. The extraction of the basic character patterns is done by examining the features of segments in character. Applying the extended DP matching method to the on-line recognition of cursive Hangeul, absorption of writing motion and stable separation of strokes can be performed with flexibility.

• Journal of the Korean Institute of Telematics and Electronics C
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• v.36C no.3
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• pp.26-34
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• 1999

A new silicon-based IC interconnect transmission line parameter extraction methodology is presented and experimentally examined. Unlike the PCB or MCM interconnects, a dominant energy propagation mode in the silicon-based IC interconnects is not quasi-TEM but slow wave mode(SWM). The transmission line parameters are extracted taking the silicon substrate effect (i.e., slow wave mode) into account. The capacitances are calculated considering silicon substrate surface as a ground. Whereas the inductances are calculated by using an effective dielectric constant. In order to verify the proposed method, test patterns were designed. Experimental data have agreement within 10%. Further, crosstalk noise simulation shows excellent agreements with the measurements which are performed with high-speed time domain measurement ( i.e., TDR/TDT measurements) for test pattern, while RC model or RLC model without silicon substrate effect show about 20~25% underestimation error.

• Journal of the Institute of Convergence Signal Processing
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• v.8 no.1
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• pp.15-21
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• 2007

We propose a 3D modeling method for surface inspection of non-constant velocity moving object. 1'lie laser lines reflect tile surface curvature. We can acquire 3D surface information by analyzing projected laser lines on object. In this paper, we use multi-line laser to improve the single stripe method and high speed of single frame. Binarization and edge extraction of frame image were proposed for robust laser each line extraction. A new labeling method was used for laser line labeling. We acquired some feature points for image matching from the frame data and juxtaposed the frames data to obtain a 3D shape image. We verified the superiority of proposed method by applying it to inspect container's damages.

• The Transactions of the Korea Information Processing Society
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• v.4 no.5
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• pp.1277-1288
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• 1997

In this paper,the extraciton method for individual and the recognition method for the printed dociments are discussed. In preprocessing is a technique to extract characters that are difficult to manage such as touching characters or overlapped chracters.Genrally in the existing segmentation methods,projection and edge detection are applied.However,in this paper an indvidual character is extracted by using connected pixel with one projection after the string extraction The maximum Blok Methld(MBM)is used for the recognition.The MBM is a method to enlarge the block to the last point the pixel that was found during projection. The maximum blocks are skeletonxied after the division into straight line block and oblique line block.Especially,in the recognition of chinese chracters compared to the existing method it showed improved recognition rate.

• Microbiology and Biotechnology Letters
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• v.15 no.2
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• pp.84-88
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• 1987

Poly(ethylene glycol)-PPB two phase system was used tot the purification of $\beta$-galactosidase from Lactobacillus sporogenes. The smaller the molecular weight of concentration of PEG phase in-creased, proteins as well as $\beta$-galactosidase was partitioned into the top phase. All cell debris were confined to the potassium phosphate phase (bottom phase), approached to the binodial line. The purification ratio increased by changing the polymer-salt composition of the tie line towards higher salt concentrations. It was also possible to obtain higher purification of the enzyme after two-step extraction using PEG 1000 and PEG 300. The top phase contained 74% of the total $\beta$-galactosidase with a purification factor of 2.1.

• Journal of KIISE:Databases
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• v.34 no.4
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• pp.343-356
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• 2007

Due to advances in position monitoring technologies such as global positioning systems and sensor networks, recent position information of moving objects has the form of streaming data which are updated continuously and rapidly. In this paper we propose an efficient trajectory maintenance method that stores the streaming position data of moving objects in the limited size of storage space and estimates past positions based on the stored data. For this, we first propose a new concept of incremental extraction of position information. The incremental extraction means that, whenever a new position is added into the system, we incrementally re-compute the new version of past position data maintained in the system using the current version of past position data and the newly added position. Next, based on the incremental extraction, we present an overall framework that stores position information and estimates past positions in the stream environment. We then propose two polynomial-based methods, line-based and curve-based methods, as the method of estimating the past positions on the framework. We also propose three incremental extraction methods: equi-width, slope-based, and recent-emphasis extraction methods. Experimental results show that the proposed incremental extraction provides the relatively high accuracy (error rate is less than 3%) even though we maintain only a little portion (only 0.1%) of past position information. In particular, the curve-based incremental extraction provides very low error rate of 1.5% even storing 0.1% of total position data. These results indicate that our incremental extraction methods provide an efficient framework for storing the position information of moving objects and estimating the past positions in the stream environment.

• Journal of the Korean Society of Food Science and Nutrition
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• v.39 no.3
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• pp.399-405
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• 2010

After Gomchui tea was prepared from leaves of Ligularia fischeri (Ledeb.) Turcz by blanching method, the antioxidant activity of major compounds in Gomchui tea was assessed. On-line HPLC-ABTS analysis revealed that caffeoylquinic acids (chlorogenic acids), such as 5-O-caffeoylquinic acid (5-CQA), 3,4-di-O-caffeoylquinic acid (3,4-DCQA), 3,5-di-O-caffeoylquinic acid (3,5-DCQA) and 4,5-di-O-caffeoylquinic acid (4,5-DCQA), were the major antioxidant compounds in Gomchui tea. The extraction efficiency of these compounds were examined in the various conditions such as extraction temperature, time and solvent. The results demonstrated that the extraction amount with water increased in proportion to extraction time (1~10 min) and temperature ($8{\sim}80^{\circ}C$). These active compounds were also extracted with water even at $8^{\circ}C$ (60% of $80^{\circ}C$), indicating that water is very good extraction solvent for extraction of these antioxidant constituents. However, the extraction efficiency of these compounds decreased when ethanol percentage in water increased. The extraction efficiency between Gomchui powder (no blanching) and tea was significantly different, and 60% of total antioxidant compounds in tea was removed from fresh leaves into water in blanching process, especially 3,5-DCQA (over 90%). Meanwhile, the sonication method didn't affect the extraction of these compounds in all solvents. These results suggest that Gomchui tea can be a good candidate for the tea beneficial to human health.