• Journal of the Korean Recycled Construction Resources Institute
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• v.4 no.1
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• pp.47-54
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• 2016

In this study, the flexural capacity of fiber reinforced concrete floor slabs were evaluated using main design loads, racking and moving loads. Based on design standards and guidelines, the magnitude and loaded area of each load were determined, and its relationship was assessed. For the application of a single load, flexural capacity should be evaluated in the edge of a floor slab. In addition, the slab with thickness and concrete strength, greater than 180mm and 35MPa, respectively, sufficiently satisfied flexural capacity with a minimum of equivalent flexural strength ratio. The combination of racking loads required the largest equivalent flexural strength ratio to satisfy the flexural capacity of the floor slab. The combination of racking and moving loads showed equivalent flexural strength ratio smaller than the case of combination of racking loads, but larger than the application of single racking or moving loads. The results of this study indicated that the flexure of fiber reinforced concrete floor slabs should be designed using the combination of design loads.

• The Korean Journal of Food And Nutrition
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• v.23 no.3
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• pp.306-310
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• 2010

This study was designed to investigate the protective effect of the combination of fucoidan and lutein against AAPH-induced oxidative stress in THP-1 cells. The combination of fucoidan and lutein existed significant antioxidant effect on AAPH-damaged THP-1 cells by using lipid peroxidation and cellular antioxidant capacity assay. Fucoidan($1\;{\mu}g/m{\ell}$) and lutein($10\;{\mu}g/m{\ell}$) did not affect at all the viability of THP-1 cells, but protected the AAPH-damage of THP-1 cells at the same concentration. The viability of THP-1 cells was 0% with 1 mM AAPH alone, the protective effect of fucoidan($1\;{\mu}g/m{\ell}$) and lutein($10\;{\mu}g/m{\ell}$) was 37% and 36%, respectively. The combination of fucoidan($1\;{\mu}g/m{\ell}$) and lutein($10\;{\mu}g/m{\ell}$) exhibited significant inhibitory effect of lipid peroxidation using TBARS assay and cellular antioxidant capacity using DCFH-DA assay. In lipid peroxidation, the TBARS value of 1 mM AAPH alone was $0.8{\pm}0.03\;nM$ MDA, its of the combination of fucoidan($1\;{\mu}g/m{\ell}$) and lutein($10\;{\mu}g/m{\ell}$) was $0.2{\pm}0.05\;nM$ MDA. In cellular antioxidant capacity, the combination of fucoidan($1\;{\mu}g/m{\ell}$) and lutein($10\;{\mu}g/m{\ell}$) exhibited significant cellular antioxidant capacity of 76%, whereas quercetin($10\;{\mu}M$) as positive control exhibited the cellular antioxidant capacity of 32%. These results indicate that the cotreatment of fucoidan and lutein protects against AAPH-induced THP-1 cell damage by inhibiting lipid peroxidation, increasing cellular antioxidant capacity.

• Journal of Microbiology and Biotechnology
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• v.23 no.8
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• pp.1116-1122
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• 2013

Cell line development is the most critical and also the most time-consuming step in the production of recombinant therapeutic proteins. In this regard, a variety of vector and cell engineering strategies have been developed for generating high-producing mammalian cells; however, the cell line engineering approach seems to show various results on different recombinant protein producer cells. In order to improve the secretory capacity of a recombinant tissue plasminogen activator (t-PA)-producing Chinese hamster ovary (CHO) cell line, we developed cell line engineering approaches based on the ceramide transfer protein (CERT) and X-box binding protein 1 (XBP1) genes. For this purpose, CERT S132A, a mutant form of CERT that is resistant to phosphorylation, and XBP1s were overexpressed in a recombinant t-PA-producing CHO cell line. Overexpression of CERT S132A increased the specific productivity of t-PA-producing CHO cells up to 35%. In contrast, the heterologous expression of XBP1s did not affect the t-PA expression rate. Our results suggest that CERT-S132A-based secretion engineering could be an effective strategy for enhancing recombinant t-PA production in CHO cells.

• Journal of the Korea Society for Simulation
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• v.21 no.2
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• pp.91-101
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• 2012

Automobile manufacturing consists of body-line, painting-line, and assembly-line. These production lines are disposed in series and go through a flow process, so according to the status of pre & post processing, a suspension happens in a line by a starvation(impossibility of production by insufficient supply) or blocking(impossibility of production by exceed capacity). Therefore, to prevent a loss of production coming from a starvation or blocking, a storage such as WBS or PBS is independently owned and operated. The paper suggests the simulation model of integrated storage which can operate it by integrating each storage performing a role as a buffer of line. Specifically, the paper found the answers about reasonable number of Stacker Crane and AGV(Automatic Guided Vehicle) and suggested a methodology of operation which is available to operate them. Also, it compared an efficiency between a model of current storage and integrated storage through simulation. As a result, it turned out that the model suggested in the paper was more efficient on suspension of painting-line stop than a current storage.

• Asian-Australasian Journal of Animal Sciences
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• v.29 no.9
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• pp.1331-1337
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• 2016

The aim of this study was to compare the growth performance, fiber characteristics of the pectoralis major muscle, and meat quality characteristics in the heavy weight (HW) and random bred control (RBC) quail lines and genders. The HW male exhibited more than two times greater body (245.7 vs 96.1 g, p<0.05) and pectoralis major muscle (PMW; 37.1 vs 11.1 g, p<0.05) weights compared to the RBC female. This growth performance in the HW line was associated with a greater muscle fiber area (1,502 vs $663.0{\mu}m^2$, p<0.001) compared to the RBC line. Greater muscle mass of the HW male was accompanied by a higher percentage of type IIB fiber compared to the HW female (64.0% vs 51.0%, p<0.05). However, muscle fiber hyperplasia (increase in fiber number) has had a somewhat limited effect on PMW between the two lines. On the other hand, the HW line harboring a higher proportion of type IIB fiber showed rapid pH decline at the early postmortem period (6.23 vs 6.41, p<0.05) and lighter meat surface (53.5 vs 47.3, p<0.05) compared to the RBC line harboring a lower proportion of type IIB fiber. There were no significant differences observed in the measurement of water-holding capacity including drip loss (2.74% vs 3.07%, p>0.05) and cooking loss (21.9% vs 20.4%, p>0.05) between the HW and RBC lines. Therefore, the HW quail line developed by selection from the RBC quail, was slightly different in the meat quality characteristics compared to the RBC line, and a marked difference was found in growth performance between the two quail lines.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.21 no.2
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• pp.303-315
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• 1997

The theoretical model for the transient probe method is the modified Jaeger model which is used perfect line source theory. The transient probe technique has been developed for the simultaneous determination of thermal conductivity, diffusivity and volumetric heat capacity of liquids. The Levenberg-Marquardt iteration method is adapted to obtain thermal property within nonlinear range. Experimental results of liquids were found to agree well with recommended thermal property data.

• Proceedings of the KIPE Conference
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• 2004.07a
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• pp.82-86
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• 2004

In this paper, a cycler system for the Lithium-Polymer battery with the large capacity of 120Ah is presented. This system is constituted as the two units for the charging and discharging. The Lithium-Polymer battery should be charged in CC and CV mode, and it is required a very high precision control of the voltage and current for the charging unit. To decrease the switching noises and harmonics, parallel operation method is adopted and utilized in the power conversion module. The discharging unit has a link AC system function to return the discharging energy of battery to AC line and has comparatively less thermal loss. These units are designed to be controlled and monitored by personal computer. The total system for the battery charging and discharging is described and presented.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.49 no.1
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• pp.26-30
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• 2000

Switching of the transmission lines(T/L) is one of the methods for wuppressing the short circuit capacity. This paper presents the T/L switching operation by using the Hopfield neural network(HNN). The switching of T/L can make the line powers and the bus voltages deteriorated, as well as the fault current decreased. Such an insecure state should be avoided when the T/L is operated to be open. In this studies, the inequality constraints are formulated into the objective function to be incorporated with the HNN. Test results show that the convergence characteristics of HNN lead to the adequate solution of T/L switching.

• Journal of Communications and Networks
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• v.16 no.3
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• pp.305-310
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• 2014

Optimal position of access point (AP) is important for multi-gigabit wireless transmission in terahertz (THz) wireless local area network (WLAN)-type applications, where there exist the THz characteristic multiple clusters in channel propagation. By considering the multiple clusters in THz indoor communications, this paper investigates the optimal AP position when two APs are issued for increasing the system capacity. Numerical results reveal that the central position of each AP within each half service region, which offers the shortest cumulated path length for line-of-sight paths, is optimal to achieve the maximal system capacity.

• Journal of Advanced Marine Engineering and Technology
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• v.33 no.4
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• pp.459-465
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• 2009

This paper considers the influence of internal heat exchangers to the efficiency of a refrigerating system. These internal heat exchangers(liquid-suction or suction-line heat exchangers) can, in some cases, yield improved system performance while in other cases they degrade system performance. A steady state mathematical model is used to analysis the performance characteristics of refrigeration system with internal heat exchanger. The influence of operating conditions, such as gas cooler pressure and evaporation temperatures, superheat in the evaporator and temperature of gas cooler outlet, to optimal dimensions of the heat exchanger is also analyzed in the paper. The main results were summarized as follows : the mass flowrate of R744, inner diameter tube and length of internal heat exchanger, and effectiveness have an effect on the cooling capacity, compressor work and RCI(Relative capacity index) of this system. With a thorough grasp of these effect, it is necessary to design the R744 compression refrigeration cycle using internal heat exchanger.