• 제목/요약/키워드: Limiting factors

검색결과 433건 처리시간 0.027초

구강 질환 진단용 제제 (Diagnostic Agents for Oral and Maxillofacial Diseases)

  • 고홍섭
    • Journal of Oral Medicine and Pain
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    • 제24권2호
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    • pp.181-187
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    • 1999
  • The most important progress in diagnostic sciences is the increased sensitivity and specificity in diagnostic procedures due to the development of newer micromethodologies and increasing availability of immunological and molecular biological reagents. The outcome of researches in this field has already provided DNA probes and antibodies which can be used for diagnosing various kinds of diseases including inherited ones. This development can be also applied to diagnose diseases in oral and maxillofacial regions. Technological advances have yielded highly sensitive test methodologies so that low analyte concentration and small sample volume are no longer limiting factors. Therefore, saliva can be useful test fluid for an array of analytes. Salivary constituents of diagnostic significance include steroid hormones, antibodies, drugs, and tumor markers. Of the proteins present in saliva, viral-specific immunoglobulins are of the greatest diagnostic interest. The development of conjugates and antigens by recombinant DNA technique and peptide synthesis is necessary for clinical application. Several kits developed for the purpose of blood testing should be modified to permit their application to saliva. The final practical outcome of researches in diagnostic sciences will be various diagnostic agents which can be used for detection of bacteria and viruses, screening and diagnosis of diseases, genetic screening for forensic individual identification. For these purposes, collaboration researches and development between institutions and companies are essential.

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치료적 방법을 연부조직 손상단계에 따라 사용하기 위한 지침에 관한 연구 (Study on Guidelines for Using Therapeutic Modalities According to Injury Phases of Soft Tissue)

  • 권원안;김식현;전경희
    • The Journal of Korean Physical Therapy
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    • 제12권3호
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    • pp.497-507
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    • 2000
  • This study was performed to understanding on guidelines for using therapeutic modalities according to injury phases of soft tissue. Clinical decisions on how and when therapeutic modalities may be used should be based on recognition of signs and symptoms. as well as some awareness of the time frames associated with the various phases of the Healing process. The physical therapist must have a sound understanding of that process in terms of the sequence of the various process of healing stage. The results of this study are as follows: 1. Once an acute injury has occured, the healing process consists of the imflammatory response phase, the fibroblastic-repair phase, and the maturation-remodeling phase and can impede by various pathologic factors. 2. Modality use in the initial acute injury phase and the inflammatory response phase should be directed toward limiting the amount of swelling and reducing pain. 3. Modality use in the Fibroblastic repair phase may be change from cold to heat. The purpose of heat is to increase circulation to the injured area to promote healing. 4. During the Maturation-Remodeling phase, some type of heating modalities, ultrasound, or short wave and microwave diathermy should be used to increase circulation to the deeper tissue. In this phases, physical therapists must control training and conditioning habits to allow the injury to heal sufficiently.

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경저부 혈관손상의 임상적 고찰 (Clinical Study of Neck Base Injury)

  • 우종수
    • Journal of Chest Surgery
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    • 제11권4호
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    • pp.378-384
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    • 1978
  • Injuries to the major vessels in the thoracic inlet require early recognition and expedient operative approach. Delayed diagnosis difficulties encountered in the operative exposure of the region are the major factors limiting successful management. This report is a review of 13 patients with vascular injuries to the neck base who were managed at Busan National University Hospital from March 1975 to September 1978 about 3 years and 6 months. The important clinical problems are delineated with emphasis on the technical aspects of operative management. 1] Among 13 cases, 8 cases were male 5 cases were female. 2] Of 28 vascular injuries, subclavian axillary vascular injuries were 22 [78%]. Stab wound was the cause in 70% of these patients. 3] Without extension 7 cases[53.8%] were managed successfully with supraclavicular, and axillary incision. Posterolateral thoracotomy one of extending 4 cases, 2 cases were used right musculoskeletal flap for management of proximal part of the subclavian artery and innominate vessel, 2 cases were used left supraclavicular incision with anterolateral thoracotomy for management of left proximal subclavian artery. One Expired. 4] Repair of vascular injury was accomplished by lateral suture of debridement and end-to end anastomosis in 17[74%]. Autogenous vein was used one for interposition graft. Ligation was required 2 arterial, 6 venous injuries. Of 8 cases which were pulseless preoperatively, 5 cases were able to palpable distal pulse. 5] Post operative complications occurred 50%. Complication of vasular repair was rare. The majority was neurologic deficit (33.3%).

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Electrochemical Behavior for a Reduction of Uranium Oxide in a $LiCl-Li_{2}O$ Molten Salt with an Integrated Cathode assembly

  • Park, Sung-Bin;Park, Byung-Heung;Seo, Chung-Seok;Jung, Ki-Jung;Park, Seong-Won
    • 한국방사성폐기물학회:학술대회논문집
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    • 한국방사성폐기물학회 2005년도 Proceedings of The 6th korea-china joint workshop on nuclear waste management
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    • pp.39-50
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    • 2005
  • Electrolytic reduction of uranium oxide to uranium metal was studied in a $LiCl-Li_{2}O$ molten salt system. The reduction mechanism of the uranium oxide to a uranium metal has been studied by means of a cyclic voltammetry. Effects of the layer thickness of the uranium oxide and the thickness of the MgO on the overpotential of the cathode and the anode were investigated by means of a chronopotentiometry. From the cyclic voltamograms, the decomposition potentials of the metal oxides are the determining factors for the mechanism of the reduction of the uranium oxide in a $LiCl-3\;wt{\%} Li_{2}O$ molten salt and the two mechanisms of the electrolytic reduction were considered with regards to the applied cathode potential. In the chronopotentiograms, the exchange current and the transfer coefficient based on the Tafel behavior were obtained with regard to the layer thickness of the uranium oxide which is loaded into the porous MgO membrane and the thickness of the porous MgO membrane. The maximum allowable currents for the changes of the layer thickness of the uranium oxide and the thickness of the MgO membrane were also obtained from the limiting potential which is the decomposition potential of LiCl.

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강우감쇠의 영향 분석을 위한 국내 각 지역의 강우강도 분포 (Rainfall-intensity distribution for an analysis of the effects of rain attenuation)

  • 이형수;신철호
    • 한국통신학회논문지
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    • 제23권4호
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    • pp.1006-1015
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    • 1998
  • 20GHz 이상의 주파수대에서 대기중 감쇠에 있어서 고려해야 할 인자로는 대기분자, 강우, 강설, 안개 등이 있으며 이 중 가장 큰 영향은 강우에 의한 감쇠이다. 강우로 인한 감쇠는 강우강도에 의해서 그 감쇠정도가 결정되고, 강우강도는 공간적 시간적으로 변동이 매우 다양하다. 따라서 강우강도에 의한 시간적 공간적 데이터의 확보와 정확한 강우강도의 추정은 정확하고 신뢰성 있는 회선설계를 위하여 필수적이다. 본 연구에서는 제주도를 제외한 남한전역의 32개 측후소로부터 얻을 수 있는 최근 10여년 간의 디지털 강우강도 데이터를 확보하여 지역별 강우강도와 시간율의 관계를 경험적으로 분석하였으며, 강우강도의 분포를 추정하기 위한 여러 가지 방법론을 비교 분석하였고 한국실정에 맞는 방법론을 제시하였다.

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Application of Silver Nanoparticles for the Control of Colletotrichum Species In Vitro and Pepper Anthracnose Disease in Field

  • Lamsal, Kabir;Kim, Sang-Woo;Jung, Jin-Hee;Kim, Yun-Seok;Kim, Kyong-Su;Lee, Youn-Su
    • Mycobiology
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    • 제39권3호
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    • pp.194-199
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    • 2011
  • Pepper anthracnose caused by Colletotrichum species is one of the most important limiting factors for pepper production in Korea, its management being strongly dependent on chemicals. The aim of this work was to evaluate the possibilities of using silver nanoparticles instead of commercial fungicides. In this study, we evaluated the effect of silver nanoparticles against pepper anthracnose under different culture conditions. Silver nanoparticles (WA-PR-WB13R) were applied at various concentrations to determine antifungal activities in vitro and in the field. The application of 100 ppm concentration of silver nanoparticles produced maximum inhibition of the growth of fungal hyphae as well as conidial germination in comparison to the control in vitro. In field trials, the inhibition of fungi was significantly high when silver nanoparticles were applied before disease outbreak on the plants. Scanning electron microscopy results indicated that the silver nanoparticles caused a detrimental effect on mycelial growth of Colletotrichum species.

Water-Side Oxide Layer Thickness Measurement of the Irradiated PWR Fuel Rod by NDT Method

  • Park, Kwang-June;Park, Yoon-Kyu;Kim, Eun-Ka
    • 한국원자력학회:학술대회논문집
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    • 한국원자력학회 1995년도 추계학술발표회논문집(2)
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    • pp.680-686
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    • 1995
  • It has been known that water-side corrosion of fuel rods in nuclear reactor is accompanied with the loss of metallic wall thickness and pickup of hydrogen. This corrosion is one of the important limiting factors ill the operating life of fuel rods. In connection with the fuel cladding corrosion, a device to measure the water-side oxide layer thickness by means of the eddy-current method without destructing the fuel rod was developed by KAERI. The device was installed on the multi-function testing bench in the nondestructive test hot-cell and its calibration was carried out successfully for the standard rod attached with plastic thin films whose thicknesses are predetermined. It shows good precision within about 10% error. And a PWR fuel rod, one of the J-44 assembly discharged from Kori nuclear power plant Unit-2, has been selected for oxide layer thickness measurements. With the result of data analysis, it appeared that the oxide layer thicknesses of Zircaloy cladding vary with the length of the fuel rod, and their thicknesses were compared with those of the destructive test results to confirm the real thicknesses.

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Managing maritime automobile terminals: an approach toward decision-support model for higher productivity

  • Beskovnik, Bojan;Twrdy, Elen
    • International Journal of Naval Architecture and Ocean Engineering
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    • 제3권4호
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    • pp.233-241
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    • 2011
  • The article describes actions and strategies to obtain higher productivity on maritime automobile terminals. The main focus is on elaboration of efficient and effective organizational structure to model and implement short-term, mid-term and long-term strategies. In addition, with an empiric approach we combined the analyses of current findings in important scientific papers and our acknowledgments in practical research of north Adriatic maritime automobile terminals. The main goal is to propose actions towards increasing system's productivity. Based on our research of the north Adriatic maritime automobile terminals and with Lambert's model an in-deep analysis of limiting factors, user's expectations and possibilities for productivity increase has been performed. Moreover, with our acknowledgments a three-level decision-support model is presented. With an adequate model implementation it is possible to efficiently develop and implement different strategies of productivity measurement and productivity increase, especially in the fields of internal transport productivity, entrance/exit truck gates operations and wagon manipulations. According to our observation a significant increase might be achieved in all three fields.

Regulation of Gene Expression for Amino Acid Biosynthesis in the Yeast, Sacchromyces cerevisiae

  • Lea, Ho Zoo
    • 한국동물학회:학술대회논문집
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    • 한국동물학회 1995년도 한국생물과학협회 학술발표대회
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    • pp.82-82
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    • 1995
  • Regulation of enzyme synthesis by transcriptional and translational control systems provides rather stable adaptation to change of amino acid level in the growth medium, while manipulation of enzyme activity through endproduct feedback inhibition represents rather short-term and reversible ways of adjusting metabolic fluctuation of amino acid level. Various control mechanisms interplay to regulate genes encoding enzymes for amino acid biosynthesis in the yeast, Sacchromyces cerevisiae. When amino acids are in short supply, genes under a cross-pathway regulatory mechanism Or general amino acid control (general control) increase their action, in which Gcn4p is the major positive regulator of gene expression. When cells are cultured in minimal medium, basal level expression is also regulated by supplementary control elements, where inorganic phosphate level is additionally involved. Most of amino acid biosynthetic genes are also regulated by the level of endproduct of the pathway. This pathway-specific regulatory mechanism is called specific amino acid control (specific controD, under which gene expression is reduced when endproduct is present in the medium. Derepression of a gene through general control can be usually overridden by repression through specific control, where the endproduct level of that particular pathway is high and not limiting. In this presentation, regulatory factors for basal level expression and general control of yeast amino acid biosynthesis will be discussed, m addition to pathway-specific repression patterns and interaction between CrOSS- and specific-control mechanisms. Preliminary results are also presented from the investigation of the cloned genes in the threonine biosynthetic pathway of the yeast. yeast.

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FEM을 이용한 진공유리 패널의 지지대 설계변수 설정 (The Pillar Design Variable Determination up of the Vacuum Glazing Panel using FEM)

  • 김재경;전의식
    • 반도체디스플레이기술학회지
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    • 제10권4호
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    • pp.101-106
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    • 2011
  • There are various methods in the flat panel display manufacture. The cost reduction effect is very big in case of using the screen printing method. The screen printing method is much used in the process of forming PDP barrier and can apply to the process of arranging the pillars for maintaining the vacuum gap of the vacuum glazing panel. The pillar which is one of the core elements for comprising vacuum glazing maintains the vacuum gap overcoming the vacuum pressure difference with the atmospheric pressure generated in vacuum glazing. At the same time, the deformation phenomenon by vacuum pressure is relived. In this paper, by using FEM about three considered in the pillar design and arrangement kinds of limiting factors, the simulation was performed. The pillar optimum arrangement method at within the maximum allowable tensile stress and heat transfer coefficients according to the arrangement try to be presented based upon the analyzed result data review and this validity tries to be verified by FEM.