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A case of Hydrocephalus in S/D Rat with the Closure of Mesencephalic Aqueduct (중뇌수도관 폐쇄에 의한 S/D계통 랫드 수뇌증 1예)

  • Cho, Ik-Hyun;Han, Kyu-Bo;Chang, Byung-Joon
    • Korean Journal of Veterinary Research
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    • v.42 no.3
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    • pp.429-436
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    • 2002
  • Hydrocepbalus may be an acquired or a congenital condition. We have studied the macroscopic and microscopic changes in the hydrocephalus of an inbred Sprague-Dawley rat at postnatal week 8. The animal suspected with the hydrocephalus showed clinical syndromes such as depression, severe ataxia, eye abnormalities, dome-shaped head, and persistent fontanelle. With the postmortem examination, the suspected animal was clearly revealed as a severe internal hydrocephalus. In this animal, severe ventriculomegaly was limited to the third and lateral ventricles, and cortical thining was most apparent in the parieto-occipital region. With the routine histological examination, brain tissue showed aqueductal obstruction, thinning of the cerebral cortex, severe ependymal damage, subependymal edema, damage of choroid plexus of fourth ventricle, enlarged cortical vessels, and expanded ventricles. Aqueductal obstruction was observed with the appearance of simple stenosis at the level of rostral colliculus. Subsequently, the other structures of brain such as septal nucleus, caudate nucleus, and hippocampus etc. were abnormally reconstructed by hydrocephalus. This study suggests that the hydrocephalus can be taken place by primary aqueductal obstruction and this type of hydrocephalus is classified as uncommunicating type. Though the mechanism of aqueductal obstruction is not clear, the morphological studies of this case may be helpful for the further study of hydrocephalus.

A Study on the Architectural Planning of Public Space of Nursing Home for the Elderly with Dementia ( I ) (치매노인요양시설의 공용부분에 관한 건축계획적 연구 ( I ))

  • Kim, Sook-Hyun;Kim, Hyun-Tae;Kim, Seon-Kook;Kim, Kwang-Moon
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.2 no.3
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    • pp.71-81
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    • 1996
  • The existing domestic and foreign elderly nursing homes, with 50 beds or more, are selected and examined according to user interview, and document analysis to understand the facts about the elderly nursing homes. The location of domestic nursing homes is limited to the region of Seoul and Kyunggi province. The scope of research is focused on the plans, area compositions, equipments and relations with public spaces - wandering paths, bathrooms and toilets. The content of research, based on the collected data discribed above, includes the search for architectural idea and the examination of typological differences among plans. The research is performed as followes. 1) description of research objectives. 2) examination of problems associated with the elderly. 3) understanding of systems and plans of domestic and foreign nursing homes. 4) performance of case study, derivation of design criteria for architectural planning, and suggestion of several adjustable alternatives for public spaces.

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Transient asymptomatic white matter lesions following Epstein-Barr virus encephalitis

  • Jang, Yoon-Young;Lee, Kye-Hyang
    • Clinical and Experimental Pediatrics
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    • v.54 no.9
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    • pp.389-393
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    • 2011
  • We present the case of a patient with Epstein-Barr virus (EBV) encephalitis who developed abnormal white matter lesions during the chronic phases of the infection. A 2-year-old-boy was admitted for a 2 day history of decreased activity with ataxic gait. The results of the physical examination were unremarkable except for generalized lethargy and enlarged tonsils with exudates. Brain magnetic resonance imaging (MRI) at admission showed multiple high signal intensities in both basal ganglia and thalami. The result of EBV polymerase chain reaction (PCR) of the cerebral spinal fluid was positive, and a serological test showed acute EBV infection. The patient was diagnosed with EBV encephalitis and recovered fully without any residual neurologic complications. Subsequently, follow-up MRI at 5 weeks revealed extensive periventricular white matter lesions. Since the patient remained clinically stable and asymptomatic during the follow-up period, no additional studies were performed and no additional treatments were provided. At the 1-year follow-up, cranial MRI showed complete disappearance of the abnormal high signal intensities previously seen in the white matter. The patient continued to remain healthy with no focal neurologic deficits on examination. This is the first case of asymptomatic self-limited white matter lesions seen in serial MRI studies in a Korean boy with EBV encephalitis.

An Examination of the Current Health of University Students and a Systematic Approach to a Healthy Campus (대학생의 건강특성 및 대학건강증진을 위한 체계적 접근방안)

  • Kim, Young-Bok
    • Korean Journal of Health Education and Promotion
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    • v.28 no.5
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    • pp.1-16
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    • 2011
  • Objectives: A healthy campus enables students to pursue their academic goals. This study examines the health in a broad spectrum of university students and suggests a systematic approach to building a healthy university campus. Methods: The Korea National Health and Nutrition Examination Survey (1998-2009) results and the American College Health Association-National College Health Assessment (2000-2011) report were used as bases for this study. Results: The most common health problems were allergies, sinusitis, ear infections, anemia, depression, and stress among both American students and Korean young people in the 19-29 age group. American students were more likely to be overweight, while Korean young people were to become underweight. College students were also less likely to practice healthy behavior(i.e. vaccinations, physical activity, and not smoking). To build a healthy university campus, six areas of health services are suggested: medical care, health education, counseling, immunization, heath promotion, and employee assistance programs (EAP). In addition, universities should develop effective strategies to improve health on campus, such as community partnerships. Conclusions: To make the most of the limited resources requires a systematic approach that focuses on continuous monitoring of health on campus, health surveys, and collaboration between universities and their communities.

Factors associated with unmet dental needs among adults with activity limitations (활동제한 성인의 미충족 치과의료에 영향을 미치는 요인)

  • Lee, Won-Ik
    • Journal of Korean society of Dental Hygiene
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    • v.20 no.5
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    • pp.571-580
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    • 2020
  • Objectives: This study aimed to investigate the factors associated with unmet dental needs among adults with activity limitations. Methods: Data were obtained from the seventh Korean National Health and Nutrition Examination Survey (KNHANES). The final sample consisted of 945 adults aged 20 years or older with limited activity. Logistic regression analysis was used to examine the influence of predisposing, enabling, and need factors on unmet dental needs. Results: The proportion of adults with unmet dental needs during the last year was 52.2% in the middle-aged group and 45.5% in the older adult group. Higher household income was associated with fewer unmet dental needs in both groups. In the older adult group, married people were less likely to have unmet dental needs. In the middle-aged group, adults who perceived their oral health as poor were more likely to have unmet dental needs. Conclusions: All three factors (predisposing, enabling, and need) were found to be associated with unmet dental needs among adults with activity limitations. Special efforts should be made to improve access to dental care services for middle-aged adults with activity limitations.

Effects on Ultrastructural Changes and Several Phosphatase Activities by Actinomycin D in Migrating Primordial Germ Cells of Developing Rat (발생중인 흰쥐 원생식세포의 이동과 미세구조 및 몇몇 Phosphatase의 활성에 미치는 Actinomycin D의 영향)

  • Choi, C.K.
    • Applied Microscopy
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    • v.15 no.1
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    • pp.1-12
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    • 1985
  • In this study, the pathway and date of migrating Primordial germ cells (PGCs) were observed light microscopically and ultrastructural changes of them during migration were observed by electron microscopic examination. For these purpose, alkaline phosphatase reactions were used for identifying the PGCs and acid phosphatase reactions were used for observing their degenerating activities. Also, effects of actinomycin D on the migration of PGCs were examined. According to these results, at the 9th gestation day, PGCs were observed in the endodermal cells of yolk sac, at the 11th gestation day, they were seen in the hindgut and then entered into the dorsal mesentery by the 13th gestation day. At the 14th gestation day, they were located in the genital ridges. When PGCs were located in the hindgut and genital ridges, the positive reactions of alkaline phosphatase were dominated, but acid phosphatase reactions were limited in all stage except they were in dorsal mesentery. However, these reactions were lessened in case of actinomycin D treatment. By electron microscopic examination, PGCs had pseudopodia, tail process, trailing cytoplasm and nuage as the ultrastructural characteristics. In addition, these morphological features were damaged by actinomycin D treatment.

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Hearing Status in Korean Adults according to the Fourth Korea National Health and Nutrition Examination Survey 2009 (한국 성인의 청력 상태: 국민건강영양조사 분석)

  • Kim, Ji-Su;Lee, Bong-Suk
    • Journal of Korean Public Health Nursing
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    • v.25 no.2
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    • pp.197-208
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    • 2011
  • Background: This study investigated the hearing status in Korean adults according to data from the Korea National Health and Nutrition Examination Survey 2009. Methods: The data of 3,479 adults(${\geq}20$ years, 1,492 men, 1,987 women) collected by the Korean Center for Disease Control was analyzed using ${\chi}^2$-test and logistic regression. Results: Differences in hearing loss according to individual factors were evident by follows gender, region, education status, economic status, current smoking and recognition of stress. Differences in - hearing loss according to ear related factors were evident subjective hearing status, experience of tinnitus, prevalence of chronic otitis media, and tympanomembrane abnormality. Conclusion: Hearing-related disorders can cause many social problems. This study investigated a representative cross-section of Koreans to determine the hearing status. The study was limited in that the risk factors of hearing loss were not identified. It is also recommended that a program be developed that can help control the variables identified in this study along with follow-up studies to verify the model.

Tooth Movement in Demineralized Area by Etchant in Rabbits

  • Choi, Bohm;Kim, Tae-Gun;Han, Seung-Hee;Park, Yoon-Hee;Lee, Won
    • Journal of Korean Dental Science
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    • v.5 no.1
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    • pp.37-44
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    • 2012
  • Purpose: Among the facilitation of tooth movement in adult orthodontic treatment methods, surgical approaches are gaining popularity but complications following mechanical bone reduction are a problem. In this study, tooth movement was observed after alveolar bone was chemically demineralized to verify whether tooth movement had been facilitated. Materials and Methods: Twelve rabbits were used. In the experimental group, the alveolar bone of the left first molar area was exposed and demineralized. Thirty seven percents phosphoric acid was applied for 5 minutes for demineralization. The opposite first molar area was used as control. Two teeth were pulled with 200 g force and 4 rabbits each were sacrificed at 3, 7, and 14 days after the force was applied. Histologic examination was done with hematoxylin and eosin and tartrate-resistant acid phosphatase staining. Result: The histologic examination results revealed more bone resorption in the demineralized area. As time passed, the number of osteoclasts increased in the compressed area. The amount of tooth movement was larger in the experimental group compared to the control group but the difference was not statistically significant. Conclusion: The demineralization with etchant resulted in limited bone resorption, more tooth movement and less damage of the cementum after applied orthodontic force.

Determinants of Quality of Life, Depending on the Presence or Absence of Asthma in Adults, Based on the 6th Korea National Health and Nutrition Examination Survey (제6기 국민건강영양조사 자료에 기초한 성인의 천식 유무에 따른 삶의 질 영향요인)

  • Jo, Eun-hee;Lee, Su-jin
    • The Korean Journal of Health Service Management
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    • v.13 no.3
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    • pp.127-136
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    • 2019
  • Objectives: This study examined the determinants of quality of life, depending on the presence or absence of asthma in adults, based on secondary wave data. Methods: Among the 21,724 people participating in the 6th Korea National Health and Nutrition Examination Survey as it was conducted from the first to third period, 495 participants who were aged 19 or older and responded to the question of the presence or absence of asthma were included in the final analysis. Demographic characteristics were examined using the SPSS/WIN 23.0 software tool for analysis of complex sample survey data. Health-related characteristics were presented using descriptive and multivariate analysis of data. Rao_Scott ${\chi}^2$ was used for the analysis of differences in quality of life, and multiple regression analysis of complex sample survey data was used to analyze factors affecting quality of life. Results: The variable factors negatively influencing quality of life were aging, cognition of their ill health, and limited activities. Conclusions: Based on the analysis, the study suggests that practical and ongoing nursing intervention proposals to improve the quality of life of asthmatic patients should be implemented not only for physical limitations and aging but also for psychological factors that reflect subjective health statuses.

Facial asymmetry: a case report of localized linear scleroderma patient with muscular strain and spasm

  • Kim, Jae-Hyung;Lee, Suck-Chul;Kim, Chul-Hoon;Kim, Bok-Joo
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.37
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    • pp.29.1-29.7
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    • 2015
  • Facial asymmetry is found in patients with or without cosmetic facial alterations. Some patients have facial asymmetry that manifests underlying skeletal problems, while others have only limited soft-tissue facial asymmetry. Orthognathic surgery brings about a dermatic change, as soft tissue covers underlying bones. Limited soft-tissue asymmetry, meanwhile, is difficult to correct. The treatment modalities for the creation or restoration of an esthetically pleasing appearance were autogenous fat grafts, cartilage graft, and silicon injections. A young female patient had right-side facial asymmetry. The clinical assessment involved visual inspection of the face and palpation to differentiate soft tissue and bone. Although the extra-oral examination found facial asymmetry with skin atrophy, the radiographic findings revealed no mandibular atrophy or deviation. She was diagnosed as localized scleroderma with muscle spasm. In conclusion, facial asymmetry patients with skeletal asymmetry can be esthetically satisfied by orthognathic surgery; however, facial atrophy patients with skin or subdermal tissue contraction need treatment by cosmetic dermatological surgery and orthodontic correction.