• 제목/요약/키워드: Light-through

검색결과 5,184건 처리시간 0.027초

LIGHT is Expressed in Foam Cells and Involved in Destabilization of Atherosclerotic Plaques through Induction of Matrix Metalloproteinase-9 and IL-8

  • Kim, Won-Jung;Lee, Won-Ha
    • IMMUNE NETWORK
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    • 제4권2호
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    • pp.116-122
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    • 2004
  • Background: LIGHT (TNFSF14) is a member of tumor necrosis factor superfamily and is the ligand for TR2 (TNFRSF14/HVEM). LIGHT is known to have proinflammatory roles in atherosclerosis. Methods: To find out the expression pattern of LIGHT in atherosclerotic plaques, immunohistochemical analysis was performed on human carotid atherosclerotic plaque specimens. LIGHT induced atherogenic events using human monocytic cell line THP-1 were also investigated. Results: Immunohistochemical analysis revealed expression of LIGHT and TR2 in foam cell rich regions in the atherosclerotic plaques. Double immunohistochemical analysis further confirmed the expression of LIGHT in foam cells. Stimulation of THP-1 cells, which express TR2, with either recombinant LIGHT or immobilized anti-TR2 monoclonal antibody induced interleukin-8 and matrix metalloproteinase(MMP)-9. Electrophoretic mobility shift assay demonstrated that LIGHT induces nuclear localization of transcription factor, nuclear factor $(NF)-{\kappa}B$. LIGHT induced activation of MMP-9 is mediated by $NF-{\kappa}B$, since treatment of THP-1 cells with the $NF-{\kappa}B$ inhibitor PDTC (pyrrolidine dithiocarbamate) completely blocked the activation of MMP-9. Conclusion: These data indicate that LIGHT is expressed in foam cells in atherosclerotic plaques and is involved in atherogenesis through activation of pro-atherogenic cytokine IL-8 and destabilization of plaque by inducing matrix degrading enzyme.

빛의 반사를 응용한 패션디자인 연구 (A Study on Fashion Design Applying Reflection of the Light)

  • 이윤정;김연희
    • 한국의상디자인학회지
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    • 제13권3호
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    • pp.1-14
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    • 2011
  • A dress is commonly designed and worn as a work of art. It is developed through various ways to show the expression of our bodies with functional aspects. Light plays a role in everyday life functionally and aesthetically. We can use the light in many different ways in order to enhance the beauty of the designs. The purpose of this study is to suggest sensible designs with the active expression of light reflection. The designs are especially focused on utilizing light that shows the combination between natural human body's movement and reflection of the light. The use of reflective materials shows the character of movement when it exposes to light. The methods allow to amplify the aesthetic effects of the designs. Reflective materials were used in the resulting design to show the various effects of light by applying the movement which is artistic and aesthetic pleasing aspect for the clothing. The movement is accentuated when the wearer moves, or the air flows through the adding materials on the clothing. In addition, the beads attached to the end of the springs to show the movement of the light. The combination of the spring and the light movement resulted in a dazzling effect. I hope in the future, more studies will be conducted to further use of fiber optics and other innovative ways to use light in fashion.

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빛과 공간의 변전에 관한 연구 (A Study on the Relation between Light and Ever-changing Space)

  • 홍승대
    • 한국디지털건축인테리어학회논문집
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    • 제8권1호
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    • pp.65-74
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    • 2008
  • Light creates ambiance that affects our impression of space. Before the modern age, the role of light is a religious factor and a primitive state to see. In the modern space design, light is used to achieve the continuous transformation and translation of building's image. Ever-changing space is a flexible corresponding of space to its environment, caused by certain dynamic light. The space turn into some other thing from what it was before, or just changing its character. approaching men and society with different meanings. The purpose of this study is to explore the relation between light(natural and artificial) and ever-changing space through the case study. The impacts of light on ever-changing in today's space design can be summarized as follows. 1) Materialization of light in space design. Nowadays light becomes a form itself. The geometric properties of the space form playa secondary role as compared to the importance assigned to light. 2) Pixelization of space by a light effect. The impacts of digital technology on the space design have come through enhancing the 'pixelization' of the surface from which buildings are made their responsiveness and adaptability to changing needs. The surface with ever-changing lights that blur the boundary of space and expand the image of space.

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활성표피를 통한 빛의 유입에 관한 연구 - 헤르조그 & 드 뫼롱의 작품을 중심으로 - (A Study on the inflow of Sunlight through the Active Building Skin - Focusing on Works of Herzog & de Meuron -)

  • 나하나;박부미
    • 한국실내디자인학회논문집
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    • 제26권4호
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    • pp.30-41
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    • 2017
  • Sunlight is perceived by human beings first through the epidermis to space, and is a non - material medium that provides physical awareness of space, diversified expression of spaces, and plenty experience. The purpose of this study is to investigate the characteristics of active building skin based on the inflow of natural light required by humans, looked through among the works of Jacques Herzog & Pierre de Meuron, which show the characteristics of active building skin, TEA(Tenerife Espacio de las Artes, 2008), Messe Basel New Hall (2013) and Elbphilharmonie (2016). First, the interaction between Sunlight and space is divided into spatial characteristics and sensitivities according to their concepts, properties, and characteristics. The characteristics of active skin by light are classified into a physical approach and a constructive approach. Second, (El Croquis 152/153) and analyzed the images, detail drawings, and elevations, and simulated them in 3D to express the relationship between light and active building skin. Third, the changes of light intensity, light color, and distribution of light according to the time of light entering and the skin are determined from 6:00 am to 6:00 pm. Fourth, the images taken from January 30th to February 7th, 2017 on the site were compared with the computer simulated images, and the relationship between active skin and light was compared. This study is to recognize the existence and necessity of light required for human being through the activated epidermis differentiated from the limited or closed epidermis focused on information transmission, I would like to emphasize that I would like to take a step closer to the necessity and possibility of new attempts and developments so that I can feel the various experiential spaces by.

Development of Awning System using Light Shelf - Focusing on the light environment and lighting energy reduction performance improvement -

  • Jeong, Jinsoo;Lee, Heangwoo;Seo, Janghoo;Kim, Yongseong
    • KIEAE Journal
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    • 제17권3호
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    • pp.5-13
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    • 2017
  • Purpose: Various studies have been performed to address the issue of increased energy use by buildings. In particular, research on complex envelopes that combines diverse envelope element techniques is currently in progress in the building sector. The present study aimed to develop an awning system using a light shelf, and to verify its validity through performance evaluation. Method: In the present study, a testbed was established for the performance evaluation of the awning system using a light shelf, and the uniformity ratio and lighting energy consumption were compared and analyzed relative to those with no awning and light shelf installation (Case 1), awning installation (Case 2), and light shelf installation (Case 3). Result: 1) In the present study, an awning system using a light shelf (Case 4) where an opening is made on the awning screen and natural light can be introduced through the light shelf located at the bottom was developed. 2) The optimum standard for Case 4 obtained through the performance evaluation was a 0.6m lighting length and a 2m extension length at a light shelf angle of $30^{\circ}$. 3) Case 4 with the optimum standard had a 5.5% lower uniformity ratio than Case 2, but had a higher uniformity ratio than Case 1 and Case 3. 4) Case 4 with the optimum standard showed 13.3%, 44.6%, and 0%~8.7% lighting energy reductions compared to Case 1, Case 2, and Case 3, respectively. 5) Based on the above results, Case 4 suggested in the present study was found to be effective for indoor light environment improvement and lighting energy reduction.

자연광과 LED조명색채 비교분석을 통한 가을빛 LED감성조명 색채 연구 (A Study on the Autumn LED Emotional Lighting Color through the comparative analysis of the Daylighting and LED Lighting Color)

  • 양정순
    • 조명전기설비학회논문지
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    • 제25권11호
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    • pp.1-13
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    • 2011
  • The purpose of this study is the realization of LED light environment closely resembling the Autumn daylight which people feel comfortable with. This research was conducted through an optical experiment and Emotional evaluation through human's eyes. Human beings are affected by the color of light, quality and light intensity. Unlike the past when human beings have worked mainly in daylight, the urbanites today spend most of the time in indoor spaces. Therefore, the artificial light is needed to strive toward a spectrum of daylight. This study is purposed to provide the pleasant light environment for human beings and build its database. This study course is expected to contribute to the new design methodology of the related fields under the development of the LED emotional lighting color.

Optimization of the Emission Spectrum of Red Color in Quantum Dot-Organic Light Emitting Diodes

  • Jeong, Byoung-Seong
    • 공업화학
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    • 제32권2호
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    • pp.214-218
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    • 2021
  • We investigated the optimal stacked structure from the perspective of process architecture (PA) through emission spectrum analysis according to the wavelength of quantum dot (QD)-organic light-emitting diodes (OLED). We confirmed that the blue-light leakage through the QD can be minimized by increasing the QD filling density above a critical value in the red QD (R-QD) layer. In addition, when the thickness of red-color filter (R-CF) at the upper part of the R-QD increased to more than 3 ㎛, the leakage of blue light through the R-CF was effectively blocked, and a very sharp emission spectrum in the red wavelength band could be obtained. According to these outstanding results, we expect that the development of QD-OLED displays with very excellent color gamut can be possibly realized.

스티븐 홀의 건축공간에서 나타나는 현상적 빛의 표현방법과 특성에 관한 연구 (A Study on the Characteristics and Expression Methods of Phenomenal Light In Steven Holl's Architecture)

  • 장현주;박찬일
    • 한국실내디자인학회논문집
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    • 제22권1호
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    • pp.143-153
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    • 2013
  • The purpose of this study is to explore how to make use of the light and expression methods to embody phenomenal space by considering the representation techniques and characteristics of a variety of 'Phenomenal light' in his works focused on the Steven Holl's views that thought the light as object of creating space. The process is summarized as follows: (1) Study on the relationship between light and color, Classify concept and type of phenomenal light by phenomenal color (2) Consider the characteristics and expression methods of the phenomenal light in the Steven Holl's architecture (3) Finally, organize the concepts and representation techniques of phenomenal light, and then present method to embody phenomenal space by light. According to this, the results are as follows: (1) Perceptual color by the light of the sense forms a variety of perception and texture of light and shadow according to the contrast of shades and the change of materiality, thus embodying multisensory space with the light as the medium approach that helps to experience formal and tactile senses. (2) Spatial color by the light of volume distinguishes the flow and movement of sight, and embody inducing space with the light as Atypical activity that forms atmosphere of space through concentrated or overlapped mass of light and darkness. (3) Existential color by the light of the light source visualizes the existence of the uncertain light, and embody the receptive space with the light as emotional communication that forms symbolic and psychological meaning through metaphorical phenomena of colored light.

빛과 어둠의 대비와 통합에 나타난 공간의 지각과 인식에 관한 연구 (A Study on Cognition and Perception of Space through Contrast and Integration of Light and Darkness)

  • 김종진
    • 한국실내디자인학회논문집
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    • 제19권5호
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    • pp.3-10
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    • 2010
  • In the history of art and architecture, there are different characteristics in relationship between light and space. Among them, two characteristics seem to be fundamental : The first is that contrast between light and darkness is more articulated. Direct sunlight penetrates into the dark interior space made by heavy masonry structure. This is generally found in the traditional western religious buildings. The second is that light is mixed with darkness and becomes shade. Shade is different from shadow that is usually perceived as the opposite of light. Sunlight is filtered under through the big horizontal roof and rice paper walls in the traditional far-east Asian architecture and becomes weak ambient light. In this shade, there is no strong contrast between light and darkness. This difference is not only originated from the architectural differences, but also originated from the conceptual differences about light, space, and the world in two cultures. This paper tries to study the philosophical, aesthetical backgrounds as well as case examples in art and architecture of two characteristics. Based on the case studies, this paper aims to analyze the main perceptual structure. Finding the relationship between light, space, and human body by making three dimensional models is the crucial analysis method of this research. Although in real life and experiencing the world, these two characteristics are not clearly separated, comparative study based on different cultures gives opportunity to think of diverse perspectives on light and space.

Light Effects on the Membrane Potential in Oat Cells

  • Kim, Kwan-Bae;Park, Moon-Hwan;Chae, Quae
    • BMB Reports
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    • 제28권5호
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    • pp.382-386
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    • 1995
  • One of the reaction pathways in light-invoked signal transduction can be initiated through ion fluxes across the plasma membrane in higher plants. We isolated protoplasts from oat coleoptile and examined the effects of light on the membrane potential using a membrane potential-sensitive fluorescent probe (bisoxonol). Both red and far-red light initially induced a hyperpolarization in oat cells. Red light-induced hyperpolarization was effectively dissipated by 100 mM $K^+$, but the hyperpolarization induced by far-red light was not depolarized by any of the cations ($K^+$, $Ca^{2+}$, $Li^+$, $Na^+$) tested. The depolarization induced by red light and $K^+$ was inhibited by 200 mM TEA, which is a $K^+$ channel blocker. These results suggest that $K^+$ influx through the inward $K^+$ channel may be a depolarization path in the phytochrome-mediated signal transduction.

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