• Title/Summary/Keyword: Light Sensory

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The role of basolateral amygdala orexin 1 receptors on the modulation of pain and psychosocial deficits in nitroglycerin-induced migraine model in adult male rats

  • Askari-Zahabi, Khadijeh;Abbasnejad, Mehdi;Kooshki, Razieh;Raoof, Maryam;Esmaeili-Mahani, Saeed;Pourrahimi, Ali Mohammad;Zamyad, Mahnaz
    • The Korean Journal of Pain
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    • v.35 no.1
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    • pp.22-32
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    • 2022
  • Background: Migraine headaches have been associated with sensory hyperactivity and anomalies in social/emotional responses. The main objective of this study was to evaluate the potential involvement of orexin 1 receptors (Orx1R) within the basolateral amygdala (BLA) in the modulation of pain and psychosocial dysfunction in a nitroglycerin (NTG)-induced rat model of migraine. Methods: Adult male Wistar rats were injected with NTG (5 mg/kg, intraperitoneal) every second day over nine days to induce migraine. The experiments were done in the following six groups (6 rats per group): untreated control, NTG, NTG plus vehicle, and NTG groups that were post-treated with intra-BLA microinjection of Orx1R antagonist SB-334867 (10, 20, and 40 nM). Thermal hyperalgesia was assessed using the hot plate and tail-flick tests. Moreover, the elevated plus maze (EPM) and open field (OF) tests were used to assess anxiety-like behaviors. The animals' sociability was evaluated using the three-chamber social task. The NTG-induced photophobia was assessed using a light-dark box. Results: We observed no change in NTG-induced thermal hyperalgesia following administration of SB-334867 (10, 20, and 40 nM). However, SB-334867 (20 and 40 nM) aggravated the NTG-induced anxiogenic responses in both the EPM and OF tasks. The NTG-induced social impairment was overpowered by SB-334867 at all doses. Time spent in the dark chamber of light-dark box was significantly increased in rats treated with SB-334867 (20 and 40 nM/rat). Conclusions: The findings suggest a role for Orx1R within the BLA in control comorbid affective complaints with migraine in rats.

Controversies on the Usefulness of Nerve Conduction Study in the Early Diagnosis of Diabetic Polyneuropathy: Pros (당뇨병성 다발신경병증의 조기 진단에서 신경전도검사의 유용성에 관한 논란: 긍정적인 관점에서)

  • Kwon, Ohyun
    • Annals of Clinical Neurophysiology
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    • v.10 no.1
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    • pp.29-32
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    • 2008
  • Although various criteria on the diagnosis of diabetic neuropathy are applied from trial to trial, being tailored in concert with its purpose, the utmost evidences of the diagnosis are subjective symptoms and objective signs of neurologic deficit. The application and interpretation of auxiliary electrophysiological test including nerve conduction study (NCS) should be made on the context of clinical pictures. The evaluation of the functions of small, thinly myelinated or unmyelinated nerve fibers has been increasingly stressed recently with the advent of newer techniques, e.g., measurement of intraepidermal fiber density, quantitative sensory testing, and autonomic function test. And the studies with those techniques have shed light to the nature of the evolution of diabetic neuropathy. The practical application of these techniques to the diagnosis of diabetic neuropathy in the individual patients, however, should be made cautiously due to several shortcomings: limited accessibility, wide overlapping zone between norm and abnormality with resultant unsatisfactory sensitivity and specificity, difficulty in performing subsequent tests, unproven quantitative correlation with clinical deficit, and invasiveness of some technique. NCS, as an extension of clinical examination, is still the most reliable electrophysiological test in evaluating neuropathy and gives the invaluable information about the nature of neuropathy, whereas the newer techniques need more refinement of the procedure and interpretation, and the accumulation of large scaled data of application to be considered as established diagnostic tools of peripheral neuropathy.

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Simulation of the virtual mackerel behavior to the trawl gear (트롤 어구에 대한 가상 고등어의 반응 행동 시뮬레이션)

  • Lee, Gun-Ho;Lee, Chun-Woo;Kim, Young-Bong;He, Pingguo;Choe, Moo-Youl
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.44 no.1
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    • pp.10-19
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    • 2008
  • This paper focuses on the mackerel's visual ability and swimming capability, and aims to describe the behavior in capture and escape process by trawl. The visual sensory systems and reaction behavior based locomotory capability were analyzed and simulated. The ability of fish to see an object depends on the light intensity and the contrast and size of the object. Swimming endurance of the fish is dependent on the swimming speed and the size of the fish. Swimming speeds of the fish are simulated 3 types of the burst speed, the prolonged speed and the sustained speed according to the time they can maintain to swim. The herding and avoiding is typical reaction of the fish to the stimuli of trawl gear in the capture process. These basic behavior patterns of the virtual mackerel to the gear are simulated. This simulation will be helpful to understand the fishing processes and make high selectivity of fishing.

The Influence of Luminous Source Affecting on the Perception of Textile Color (직물색의 지각에 미치는 광원의 영향)

  • Choi, Na-Young;Yang, Lee-Na;Lee, Jong-Sook
    • The Research Journal of the Costume Culture
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    • v.15 no.2 s.67
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    • pp.214-220
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    • 2007
  • The purpose of this study is to derive the use of the luminous source corresponding to the intention and contribute to product display by visually evaluating the relations between luminous source and colors, analyzing and reviewing the subjective perceptions depending on the luminous source, and clarifying the colors of artificial luminous source that look close to natural lights by each color. Hence, the researcher objectified the subjective evaluation for which they used sensory evaluation method with four colors of luminous sources(natural colors, 2800K, 4200K, and 6500K) and five colors of textiles(purple, blue, green, yellow, and red) by quantifying the evaluation. As a result, we could obtain the conclusion as follows. As for the temperature of textile colors under artificial luminous sources that appeared most close to the colors of textiles under natural luminous sources, 6500K was most frequent, and the temperature of the luminous sources that appeared most different was 2800K. However, as there were also 4200K colors that looked most close to the textile colors under natural light source, it was observed that the temperature differs depending on the textile colors. In addition, less glossy textiles exhibited more visual changes by luminous source colors than comparatively more glossy textiles, and it was observed that the most influenced color was purple, as purple has shown the largest difference among colors.

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A Study on Space Expression According to the Production Characteristics of Reflex Media (영상미디어 연출 특성에 따른 공간 표현에 관한 연구)

  • Yoo Jae-Yeup
    • Korean Institute of Interior Design Journal
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    • v.13 no.6
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    • pp.175-183
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    • 2004
  • As the information-oriented society makes progress, the role of Image has much influence on human being in space as a medium for information delivery and a means of artistic communication. These influences are appeared as expressional characteristics of the image such as the reproducibility of reality and unreality in the real world, the synchrony of expression of time, visual formality, a sign and the transmission of moaning. For these, the investigator examined the meaning of image in aspace, taking into consideration of the interrelationship of image, space, and human being. As study findings show, the expressional characteristics of image in space have such visual effects as a space in which pictorial formality and object exists, in which the mutual understanding of communication exists, and that realizes immaterial membrane in the aspect of time and space, according to the electronic light, color, and formation of the image media. In addition, it become clear that the characteristic could be staged on various circumstances by constructing the relationship between an object and a point of time interactively with bidirectional communication through combining technology and art. This suggests that the image develops as the form of sensory communication via interacting of space and human being.

Morphological and Histochemical Study on the Anterior Tentacular Antenna of a Korean Slug, Incilaria fruhstorferi (한국산 산민달팽이 ( Incilaria fruhstorferi ) 전촉각의 형태 및 조직화학적 연구)

  • 김영언;장남섭
    • The Korean Journal of Malacology
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    • v.11 no.2
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    • pp.135-145
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    • 1995
  • A morphological andk histochimical study on the amterior tintacular antenna of Korean sulg, Incilaria fruhstorferi was conducted under the light microscopic observations. The histological sturctures of the antenna were apparently divided into three parts such as the epithelium, the connective tissues and the muscular layers. The cells forming the antenna were classified into several types on the basis of their morphological and histochemical characteristics. The simple columnar epithelium cotering the whole antenna was composed of supporting cells, sensory neurons and type-a clear cells. The connective tissue was consisted of dispersed large cells, type-b clear cells and 7 types of secretory cills such as type-A, type-B, type-F, thpe-G, type-H, type-J and type-K. The large cells found in the form of group situated only in the stalk of the antenna. The large cells possessed relatively small nuclei as compared with their cytoplasm. The cytoplasm positively reacted upon alcian blue, and the nucleus was PASpositive. The type-a and type-b clear cells which were irregular in shape showed no evident reaction against various stains employed in the present study. The secrtory cells were observed mainly in the connective tissues and in the muscular layers. Histochemical components of the type-A, type-B and K were identified as acid mucopolysaccharides and those of type-F and H were neutral mucopolysaccharides. The muscular layders supporting the epithelium possessed the type-B and F secretory cells which were also observed in the connective tissues.

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Characteristics by the Behaviour and Habits of the Common Octopus (Octopus minor) (낙지 (Octopus minor)의 습성 및 행동 특성)

  • CHANG Duk Jong;KIM Dae An
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.36 no.6
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    • pp.735-742
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    • 2003
  • In order to develop a logical method for using selective fishing gear, the behaviour and habits of the aquatic animals must be investigated. However, until now, little national research has been carried out to investigate the behaviour and habits of the common octopus (Octopus minor). The purpose of this study henceforth, is to compile necessary behavioral data to develop fishing gear to catch the common octopus. Behaviour and habits of the common octopus were observed while breeding in a water tank from February to May, 2003. The feeding habits of common octopus are more vigorous at night than in the daytime. The common octopus feeds on 1-4 bait crabs per day and consume each crab in 40-50 min. The sensory organs of the common octopus are more influenced by the sense of touch and smell, than by vision. Using live bait is more effective and advantageous than using dead bait, as the common octopus responded more to live bait. The hiding habits of the common octopus were very intensive, as they hid around all the shelters that were provided in this study. They demonstrated territorial behavior and struggled to maintain their sphere of influence. In addition, out of the various colors for shelters and bait supplied, the common octopus preferred light colors.

Study on the Sense Space by Merleau-Ponty's Phenomenological body Perception (메를로-퐁티의 신체지각을 통한 감성 공간 연구)

  • Lee, Chan;Choi, Young-Jae
    • Korean Institute of Interior Design Journal
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    • v.17 no.2
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    • pp.39-46
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    • 2008
  • This paper is a research about the expression and characteristics of sense space by a phenomenological approach through body from an anthropocentric point of view. The phenomenological expression elements of sense space have been abstracted by putting the characteristics of body perception into shape through the phenomenological approach. This research aims to provide the expression and characteristics of sense space that can be applied by phenomenological elements of emotional expression, and analyze their application level by phenomenological body perception in space through corresponding examples. As a result of this research, the expressions of sense space approach - such as migration of moving lines, reiteration and segmentation of region, spatial flexibility, transferal of sense, stimulation of combined senses, symbolic abstraction of memory, perception of environment and space, time by light, phenomenal water space, time expression by surrounding environments etc. - and the characteristics of sense space according to each expression have been obtained through the phenomenological expression elements in sense space such as expansive perception by consecutive scenes, spatial and sensory experience, embodiment of place, phenomenal change by time. It aims to grope for a new approach and possibility to the embodiment and expression of sense space through the expression of sense space approach based on the phenomenological body perception.

A Study of the influence of stimulus on newborn infant생s response -Specifically in heart rate change- (감각적 자극에 따른 신생아 반응에 관한 연구 -심박동수를 중심으로-)

  • 이자형;하영수
    • Journal of Korean Academy of Nursing
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    • v.13 no.3
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    • pp.119-126
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    • 1983
  • Early extra-uterine development of the newborn infant has the potential for clarifying important questions of nature and care taking environment. In this study, tactile and auditory stimulation is used on .a group of infants to determine the effects of their response. Infants were tested by EKG at 24∼48 hrs after birth ana all they are free from complication. Stimuli presented were-touch and sound (40dB, 70dB and 40∼70dB). The result of the study were as follows: 1) The heart rate was seen to depend on their sleep-wake state. (light sleep ; 125/min, eyes: open & motor activity increase ; 151/min crying ; 185/min). 2) The heart rate affected by tactile & auditory stimulus. The heart rate response was acceleration above the prestimulus level. (tactile, 231min increase, auditory ; 16∼21/min increase), and heart rate change was seen to depend on prestimulus rate. (γ=.73) 3) There was a decrease in heart rate when they were soothe. (touch ; 24.8sec, 21/min decrease, pacifier ; 14.5sec, 26/min decrease) and significant difference in time between touch and pacifier (t= 1.76, p<0.05). This result support the evaluation of newborn infant's sensory abilitics, and has even begin to influence changes in nursing care. But systemic monitoring of newborn infants response would. further define.

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Development of electric vehicle maintenance education ability using digital twin technology and VR

  • Lee, Sang-Hyun;Jung, Byeong-Soo
    • International Journal of Advanced Culture Technology
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    • v.8 no.2
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    • pp.58-67
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    • 2020
  • In this paper, the maintenance training manual of EV vehicle was produced by utilizing digital twin technology and various sensors such as IR-based light house tracking and head tracker. In addition, through digital twin technology and VR to provide high immersiveness to users, sensory content creation technology was secured through animation and effect realization suitable for EV vehicle maintenance situation. EV vehicle maintenance training manual is 3D engine programming and real-time creation of 3D objects and minimization of screen obstacles and selection of specific menus in virtual space in the form of training simulation. In addition, automatic output from the Head Mount Display (HUD), EV vehicle maintenance and inspection, etc., user can easily operate content was produced. This technology development can enhance immersion to users through implementation of detailed scenarios for maintenance / inspection of EV vehicles" and 3D parts display by procedure, realization of animations and effects for maintenance situations. Through this study, familiarity with improving the quality of education and safety accidents and correct maintenance process and the experienced person was very helpful in learning how to use equipment naturally and how to maintain EV vehicles.