• Journal of Korean Traditional Oncology
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• v.24 no.1
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• pp.19-28
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• 2019

Objective : The purpose of this study is to report and observe effects of Integrative Cancer Treatment (ICT) on metastatic breast cancer patient. Method : A left breast cancer patient diagnosed with recurrence on liver and bones April 2018. The patient had received paclitaxel chemotherapy for two months and discontinued it because of tumor progression and side effects. The patient has been treated with ICT since March 2018 and has been taking capecitabine since October 2018. The clinical outcomes were measured by computed tomography, laboratory findings including tumor markers (CEA, CA15-3). The clinical outcomes were measured by computed tomography, laboratory findings including tumor markers (CEA, CA15-3), liver function test (AST, ALT), Eastern Cooperative Oncology Group performance status (ECOG PS), and numeric rating scales (NRS). Results : After the ICT, tumor size was partially decreased accompanying by reducing the levels of tumor markers. Major clinical symptoms induced by paclitaxel chemotherapy were improved. There were no severe adverse events induced by ICT based on National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) version 5.0. Conclusion : This case suggests that ICT may have synergistic effect for the treatment of metastatic breast cancer patient in conjunction with capecitabine.

• Nutrition Research and Practice
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• v.12 no.6
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• pp.512-520
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• 2018

BACKGROUND/OBJECTIVES: The 6-23 months for infants is the longest period in the "first 1,000 days" of life. This period is very important for child development, so complementary feeding (CF) practices should be optimized to maximize children's potential for growth and development. The aim of this study was to analyze the CF practices and nutritional status of children aged 6-23 months. SUBJECTS/METHODS: For this cross-sectional study, 392 children aged 6-23 months were selected using stratified random sampling. Socio-demographic data were collected through interviews. CF practices, collected by interviews and repeated 24-hour food recall method, were the timely introduction of CF, minimum meal frequency, dietary diversity and minimum acceptable diet, consumption food rich in proteins and vitamin A. Nutritional status was assessed using the indicators of underweight, wasting and stunting. To analyze the association between socio-demographic indicators and CF with nutritional status, the chi-square test with a confidence interval of 95% was used. RESULTS: Results showed that 39% were exclusively breastfed, only 61% received prolonged breastfeeding and 50% received timely introduction of CF. Minimum meal frequency was met by 74% of subjects, but dietary diversity and minimum acceptable diet were only realized in 50% and 40% of the children, respectively. The prevalence of underweight, wasting, and stunting were 26%, 23%, and 28%, respectively. Age of the child, birth order, birth weight, parents' education level, family size and incidence of fever and diarrhea during the previous two weeks were associated with underweight, while child's birth order, fathers' education level, mother's age, family size, completion of the age-appropriate vaccination and fish consumption frequency were associated with wasting. Age of the child, incidence of fever and acute respiratory infection, and fortified food consumption were associated with stunting. CONCLUSIONS: Suboptimal CF practices and high prevalence of underweight, wasting and stunting were found among children aged 6-23 months old in Aceh. These results highlight the need to improve CF and nutritional status.

• Journal of The Korean Society of Agricultural Engineers
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• v.61 no.2
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• pp.97-104
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• 2019

The purpose of this study was to establish the estimation method of irrigation water amount for sewage treated water reuse for agricultural purpose. To calculate the irrigation water amount, we adopted Penman-Monteith for potential evapotranspiration estimation and applied crop coefficient and irrigation efficiency factor. We developed the irrigation water amount calculation program using C language in Xcode environment. The target district for calculation is having 259 ha of agricultural land located near the Jinyeong Clear Water Circulation Center in Hanrim-myeon, Gimhae city. The meteorological data of the study area were obtained from Changwon weather station from 1986 to 2017. Calculated average and maximum of annual mean potential evapotranspiration were 2.72 mm/day and 6.22 mm/day, respectively. We used K-S (Kolmogorov-Smirnov) for goodness-of-fit test to find optimal probability distribution of annual mean and maximum evapotranspiration. As a result, the normal distribution was selected for the appropriate distribution. The annual mean and maximum potential evapotranspiration for 10-year return period by applying normal distribution were 2.88 mm/day and 6.76 mm/day, respectively. Assuming that the irrigation efficiency is 80%, the irrigation water requirement was calculated as $36.05m^3/day/ha$ and $84.45m^3/day/ha$, respectively, when annual mean and maximum potential evapotranspiration were applied. The actual irrigation water amount can be calculated by applying the crop coefficient and cropping days for the study area based on the developed irrigation water amount estimation program in this study.

• Journal of Apiculture
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• v.33 no.4
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• pp.283-295
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• 2018

As Sacbrood virus (SBV), a causative agent of larval death and colony collapse in Apis cerana honey bee, is prevalent and poses one of the most significant threats to the Korean apiculture, development of methods to counter this viral disease is urgently needed. In this study we tested some SBV controlling methods, such as requeen, shook swam, adding Apis mellifera and spraying yogurt to SBV inoculated colony. Colony size measured by number of sealed brood and adult were evaluated every 15 days until two months while instances of recurrence were recorded up to five months after applying treatment methods. We also test the effects of yogurt on healthy and SBV-infected larvae at both in vitro reared larvae and colony level. Our result showed that all SBV controlling methods had similar success rates with respect to elimination of SBV clinical symptom up to 30 days post treatment. Mix-species and spraying yogurt method had similar pattern of sealed brood and adult number and higher than that of other SBV controlling methods up to 45 days post treatment. These two groups also showed the lower percentage of SBV recurrence (50% and 66.7%) at 120 days post treatment than other group that mostly colony had clinical symptom. Result on in vitro reared larvae challenged with yogurt showed that yogurt have neither harmless on healthy larvae nor remedial effect on SBV infected larvae. However, at colony level, colony in group received yogurt treatment removed significantly more SBV-infected larvae, SBV-killed larvae, and even healthy larvae in comparison to the control, suggested that yogurt could trigger the hygienic behavior of nurse bee. Our results recommended that it is practical in beekeeping by adding A. mellifera and spraying yogurt to control SBV in A. cerana colony.

• Journal of the Korean Institute of Rural Architecture
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• v.23 no.4
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• pp.38-45
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• 2021

In this study, air quality conditions were identified and analyzed in real time, at the same time, living habits and ventilation methods were maintained in the daily life of residents, and thus, this present study focuses on the lifestyles of residents. Previous studies showed a difference from this study, focusing on the study on the effects of changes in indoor air quality on human health according to the indoor air quality process test standards of the Ministry of Environment. Formaldehyde concentrations exceeded all ventilation standards, but satisfied the organic standards of the Ministry of Environment when ventilation devices and air purifiers were activated. As such, it was investigated that a large amount of formaldehyde emission in the condo is initially ventilated, but a certain concentration is maintained. The change in PM2.5 concentration according to the ventilation method showed a clear difference. As a result of simulating indoor air flow during natural ventilation, the effects of wind speed and wind direction affect the flow rate of indoor air, and indoor polluted air is stagnant even in the presence of wind and is not completely discharged. When the risk assessment results are averaged on the day of measurement, the trends of change between adults and children are almost equivalent, but the results address that children are more sensitive to risk than adults.

• Journal of the Korean Wood Science and Technology
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• v.50 no.4
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• pp.246-255
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• 2022

The need for non-destructive testing and evaluation of Korean traditional wooden buildings is increasing because of their widespread deterioration. Among all types of deterioration, termite damage in wooden columns is the most difficult to detect with the naked eye because it starts inside the wood, and the initial deterioration is small. X-ray computed tomography (CT) is the best technology to investigate the inner state of wood that has less damage, but applying it to wooden columns between walls is challenging. Therefore, the feasibility of tomosynthesis, which is a method to reconstruct a coronal section of a subject with a few X-ray projections from a limited angle of rotation, was studied as an alternative to CT. Pine (P. densiflora) with three artificial holes was prepared as a specimen to evaluate the quality of reconstructed tomosynthesis images according to the different number of projections. The quality of the tomosynthesis images in the in-focus plane was evaluated using the contrast-to-noise ratios, while a vertical resolution between the images was assessed by determining the artificial spread function. The quality of the tomosynthesis image in the in-focus plane increased as the number of projections increased and then remained constant as the number of projections reached 21 or over. In the case of vertical resolution, there was no significant difference when 21 projections or more were used to reconstruct the images. A distinct difference between coronal section images was found when the distance was more than 10 mm from one plane to another plane.

• Journal of The Korean Society of Integrative Medicine
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• v.11 no.1
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• pp.53-62
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• 2023

Purpose : This study evaluated the effects of transcranial direct current stimulation and a virtual reality program on the depression, hand functions, cognitive function, and activities of daily living of patients with mild cognitive impairment by dividing 20 patients with mild cognitive impairment and depression. The 20 patients were divided into a treatment group (transcranial direct current stimulation + a virtual reality program) and a control group (placebo transcranial direct current stimulation + a placebo virtual reality program). Methods : This study allocated ten subjects to the treatment group and ten subjects to the control group. The treatment was given five times per week for six weeks (30 sessions), and each session was 30 minutes. This study screened depression by using SGDS-K, a short geriatric depression scale, to examine depression before and after treatment intervention. This study also used the box and block test, NCSE, and FIM to evaluate hand functions, cognitive function, and activities of daily living, respectively. Results : The results showed that depression significantly decreased, hand functions significantly increased, cognitive function significantly improved, and activities of daily living significantly increased after intervention in the treatment and control groups. The magnitude of changes in depression, hand functions, cognitive function, and activities of daily living was significantly different between the two groups after intervention (p>.05). Conclusion : The results showed that the application of transcranial direct current stimulation and a virtual reality program could improve cognitive function, hand functions, and activities of daily living by decreasing depression. Therefore, it can be concluded that the simultaneous application of transcranial direct current stimulation and a virtual reality program is an intervention method, which can be applied for decreasing depression, enhancing hand functions, improving cognitive function, and increasing activities of daily living in patients with mild cognitive impairment.

• Nuclear Engineering and Technology
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• v.54 no.11
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• pp.4111-4124
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• 2022

The control rod drive system is critical to the reactor's reliable operation. The performance of its control system and mechanical system will gradually deteriorate because of operational and environmental stresses, thus increasing the reactor's operational risk. Currently there are few researches on the aging-related degradation of the entire control rod drive system. Because it is difficult to quantify the effect of various environmental stresses and establish an accurate physical model when multiple mechanisms superimposed in the degradation process. Therefore, this paper investigates the aging-related degradation of a control rod drive system by integrating Dynamic Object-Oriented Bayesian Network and Hidden Markov Model. Uncertainties in the degradation of the control system and mechanical system are addressed by using fuzzy theory and the Hidden Markov Model respectively. A system which consists of eight control rod drive mechanisms divided into two groups is used to demonstrate the method. The aging-related degradation of the control rod drive system is analyzed by the Bayesian inference algorithm based on the accelerated life test data, and the impact of different operating schemes on the system performance is also investigated. Meanwhile, the components or units that have major impact on the system's performance are identified at different operational phases. Finally, several essential safety measures are suggested to mitigate the risk caused by the system degradation.

• Journal of radiological science and technology
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• v.46 no.5
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• pp.401-408
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• 2023

Thyroid uptake measurements can be subject to measurement errors due to the scoping and positioning of the thyroid gland. To compensate for these limitations, the clinical utility of the thyroid simultaneous counting method as an alternative to thyroid uptake measurement was analyzed and evaluated experimentally through quantitative analysis of images acquired after thyroid scanning. Experimental data were obtained using a Gamma camera (GE infinia), a thyroid uptake system (KOROID 1), and a thyroid neck phantom. Based on the thyroid uptake rate of 1-5% according to the protocol of thyroid scan test (^99mTcO₄ - , 370 MBq) in normal results, ^99mTcO₄ - was set in the range of 3.7-18.5 MBq (Matrix: 256×256, Scan time: 1 min, collimator: pin hole, phantom-collimator distances: 7 cm). The acquired images were corrected for the attenuation of isotopes due to the set-up time and half-life by applying the Auto Region of interest (ROI) drawing system, and the significance of the experimental results was evaluated by Multiple linear regression analysis (SPSS, ver. 22, IBM). The thyroid uptake rate showed a significant correlation between the dose and the measured counts when using the thyroid uptake system equipment. Meanwhile, the quantitative analysis counts of phantom images using Gamma camera also showed a significant correlation. Thus confirmed that the correlation between these two experiments was statistically significant (P<0.05). The simultaneous counting protocol, which indirectly measures thyroid uptake from thyroid scans, is likely to be clinically relevant if complemented by additional studies with different variables in patients with thyroid disease.

• Journal of radiological science and technology
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• v.46 no.5
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• pp.435-444
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• 2023

The purpose of this study was to analyze the factors that demographic factors, radiation knowledge level, and radiation awareness could be affecting the benefits of radiation. From July 2022 to July 2023, after receiving consent to participate by using the link of Naver through Social Network Service (SNS) for the general public, 312 people were surveyed by self-registration method without collecting personal information. The questionnaire consisted of a total of 25 questions following demographic factors (5 questions including age group by life cycle, sex, monthly household income, residence), radiation knowledge level (8 questions including basic physical, biological effects, radiation protection technology), radiation awareness (12 questions including risk, management, benefit). Independent sample T-test and ANOVA tests were performed for significant differences in the average radiation awareness between variables, and hierarchical regression was performed to identify influencing factors on radiation benefits. As a result, the benefit of radiation was significantly high among the radiation awareness, but the awareness of the danger of radiation was insufficient to the level of recognizing it as safe. Men had significantly higher awareness of radiation management and benefits than women, and the awareness of radiation management was significantly higher in the middle class with a monthly household income of 4.31 million won or more. The higher the knowledge level of radiation, the higher the awareness of the benefits of radiation. The factors that had a positive effect on radiation benefits were the high level of radiation knowledge and awareness of radiation management.