• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제22권4호
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• pp.287-293
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• 2011

Objectives : The region of chromosome 5p14 is known to be associated with autism spectrum disorder (ASD). The cadherin9 (CDH9) and cadherin10 (CDH10) genes are located in the region of chromosome 5p14 and reported to be associated with ASD in the Caucasian population. We performed an association study to identify if single nucleotide polymorphisms (SNPs) located on the CDH9 and CDH10 genes are associated in the Korean population. Methods : Genomic DNA was extracted from the blood of 214 patients with ASD and 258 controls. SNPs selected from two genes were genotyped using an Illumina Golden-Gate Genotyping assay with VeraCode technology. Statistical analysis was performed using SAS and Plink software. Results : All controls and ASD patients were in Hardy-Weinberg equilibrium. In the results of logistic regression analyses for the genotype model and the chi-square test for the allele model, we found that SNPs on the CDH9 and CDH10 genes were not associated with ASD. Conclusion : Our data suggests that the CDH9 and CDH10 genes are not associated with ASD in the Korean population.

• 한국환경복원기술학회지
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• 제9권1호
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• pp.14-30
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• 2006

It is difficult to secure public lots in the downtown area, school lots can be made the best use of important source to increase the area of green land in the city. The tree-planting campaign for schools has been in force since 1999 by the city of Seoul and at present; it is currently established as the plan of school parks. Thereupon, the purpose of this study is to present some ways to revitalize elementary schools to be used as vest pocket parks through the research of elementary schools, which are subject to the plan of school parks in Seoul. The results of this study are as below : The subjects to revitalize school parks as vest pocket parks are as follows. First, the land has to be utilized for security of space. Second, in addition to the front and back gate, another passage to the park has to be set up for easy access. Third, the fence has to be formed as a hedge used outside the park. Fourth, selecting plants, species of trees suitable for the landscape of school and taking into consideration the aspect of ecology. Finally, it is urgent to enact socially and economically proper standard of law by the new standards of area for school landscape considering not only the building law and regulations of general landscape, but also specific characteristics of school landscape.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2016년도 제50회 동계 정기학술대회 초록집
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• pp.278-278
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• 2016

Solution-processed metal-oxide semiconductors have been considered as the next generation semiconducting materials for transparent and flexible electronics due to their high electrical performance. Moreover, since the oxide semiconductors show high sensitivity to light illumination and possess persistent photoconductivity (PPC), these properties can be utilized in realizing optical memory devices, which can transport information much faster than the electrons. In previous works, metal-oxide semiconductors are utilized as a memory device by using the light (i.e. illumination does the "writing", no-gate bias recovery the "reading" operations) [1]. The key issues for realizing the optical memory devices is to have high photoconductivity and a long life time of free electrons in the oxide semiconductors. However, mono-layered indium-zinc-oxide (IZO) and mono-layered indium-gallium-zinc-oxide (IGZO) have limited photoconductivity and relaxation time of 570 nA, 122 sec, 190 nA and 53 sec, respectively. Here, we boosted up the photoconductivity and relaxation time using a double-layered IZO/IGZO active layer structure. Solution-processed IZO (top) and IGZO (bottom) layers are prepared on a Si/SiO2 wafer and we utilized the conventional thermal annealing method. To investigate the photoconductivity and relaxation time, we exposed 9 mW/cm2 intensity light for 30 sec and the decaying behaviors were evaluated. It was found that the double-layered IZO/IGZO showed high photoconductivity and relaxation time of 28 uA and 1048 sec.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2015년도 제49회 하계 정기학술대회 초록집
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• pp.51.2-51.2
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• 2015

Understanding interfacial phenomena has been one of the main research issues not only in semiconductors but only in life sciences. I have been trying to meet the atomic scale surface and interface analysis challenges from semiconductor industries and furthermore to extend the application scope to biomedical areas. Optical imaing has been most widely and successfully used for biomedical imaging but complementary ion beam imaging techniques based on mass spectrometry and ion scattering can provide more detailed molecular specific and nanoscale information In this presentation, I will review the 27 years history of medium energy ion scattering (MEIS) development at KRISS and DGIST for nanoanalysis. A electrostatic MEIS system constructed at KRISS after the FOM, Netherland design had been successfully applied for the gate oxide analysis and quantitative surface analysis. Recenlty, we developed time-of-flight (TOF) MEIS system, for the first time in the world. With TOF-MEIS, we reported quantitative compositional profiling with single atomic layer resolution for 0.5~3 nm CdSe/ZnS conjugated QDs and ultra shallow junctions and FINFET's of As implanted Si. With this new TOF-MEIS nano analysis technique, details of nano-structured materials could be measured quantitatively. Progresses in TOF-MEIS analysis in various nano & bio technology will be discussed. For last 10 years, I have been trying to develop multimodal nanobio imaging techniques for cardiovascular and brain tissues. Firstly, in atherosclerotic plaque imaging, using, coherent anti-stokes raman scattering (CARS) and time-of-flight secondary ion mass spectrometry (TOF-SIMS) multimodal analysis showed that increased cholesterol palmitate may contribute to the formation of a necrotic core by increasing cell death. Secondly, surface plasmon resonance imaging ellipsometry (SPRIE) was developed for cell biointerface imaging of cell adhesion, migration, and infiltration dynamics for HUVEC, CASMC, and T cells. Thirdly, we developed an ambient mass spectrometric imaging system for live cells and tissues. Preliminary results on mouse brain hippocampus and hypotahlamus will be presented. In conclusions, multimodal optical and mass spectrometric imaging privides overall structural and morphological information with complementary molecular specific information, which can be a useful methodology for biomedical studies. Future challenges in optical and mass spectrometric imaging for new biomedical applications will be discussed.

• 대한기계학회논문집 C: 기술과 교육
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• 제1권1호
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• pp.139-145
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• 2013

경량전철시스템은 버스와 지하철의 중간정도의 수송능력을 가진 첨단 대중 교통수단으로 주로 무인으로 운전되며, 1개사업이 조단위의 건설비가 소요되는 대형 복합시스템이다. 이러한 경량전철사업을 효율적으로 수행하기 위해서는 시스템엔지니어링이 매우 중요하다. 시스템엔지니어링은 성공적인 시스템을 구현하기 위한 다분야 학문의 종합적 접근방법과 수단으로 복잡한 시스템을 개발 관리하기 위해 전체적(holistic), 생명주기적 관점에서 접근하며, 필요한 사항을 확인하고, 해야 할 일을 바르게 수행하도록 안내한다. 본 논문에서는 경량전철사업에서 시스템엔지니어링을 적용하기 위한 프로세스를 제시한다. 이를 위해 국내 경량전철사업의 시스템엔지니어링 특징을 분석하고, 국내에 적합한 시스템엔지니어링 프로세스와 프로세스의 산출물 작성을 위한 템플릿과 사례, 그리고 프로세스를 전산으로 구현한 사례를 제시한다.

• 지능정보연구
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• 제12권3호
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• pp.83-93
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• 2006

이 논문은 RFID를 이용한 무선 위치 인식 기술에 대한 것이다. 데이터의 RF 분석에 의한 수신된 신호의 강도로써 위치를 파악하고 위치 특성을 이해하는 실험을 하였다. 이 실험 시스템은 외부 환경 요인을 고려한 상태에서 5000대의 단말기를 이용하여 연구하였다. 이 위치 서비스는 특히 구매, 물류, 제조와 같은 일반산업, 자동조명/공조연동, 주차장 GATE 연동 서비스 등과 같은 많은 산업에서 이용될 것이다. 이 기술의 최적 솔루션은 일상생활의 지능형 정보가 필요하는 데이터의 저장과 접촉 비접촉에 토대를 둔 스마트 카드(전화카드, 은행카드..)등에도 이용될 것이다. 실내 위치 실험 방법은 서비스 및 추정된 위치 데이터를 이용한다. 이 연구의 결과는 아래와 같다. 첫째, Active RFID의 위치인식 시스템 설치 운영의 효율성과 둘째, 실내 무선위치 시스템의 추후 지능형 정보가 필요하는 여러 분야에서의 적용 가능성실험에 있다.

• 대한한의학원전학회지
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• 제27권4호
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• pp.29-38
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• 2014

Objectives : In ministerial-fire theory(相火論) of Zhu Dan-Xi(朱丹溪), the meanings of monarch-fire(君火) and ministerial-fire(相火) described in papers published nowadays are not the same. Therefore, it is necessary to rebuild a clear concept. Methods : To understand the relationships among 'heaven(天)'-'human(人)' and 'name(名)'-'position(位)', the core concept of the ministerial-fire theory(相火論) of Zhu Dan-Xi(朱丹溪), I examined the relationships between 'heaven(天)' and 'human(人)' in Neo-Confucianism(性理學) of Song(宋) Dynasty and reviewed the notes of Wang Bing(王冰) which were quoted by Zhu Dan-Xi(朱丹溪) to set the concept of monarch-fire(君火) and ministerial-fire(相火). I studied relevant texts. Results : In ministerial-fire theory(相火論) of Zhu Dan-Xi(朱丹溪), monarch-fire(君火) is perceived as being from greed(人欲) that can cause hyperactivity(妄動) of ministerial-fire(相火), whereas ministerial-fire(相火) is perceived as being able to control monarch-fire(君火) by following the orders from heaven. This point of view is different from the past which recognized monarch-fire (君火) as the owner and ministerial-fire(相火) as the servant. Conclusions : Zhu Dan-Xi(朱丹溪) received the ideological impact of Neo-Confucianism, and accepted the notes of Wang Bing, recognized monarch-fire(君火) as 'name(名)' and ministerial-fire(相火) as 'position(位)', so he voiced the ministerial-fire theory(相火論) that perceived monarch-fire(君火) as fire(火) of the five processes(五行) of human body that came from greed, ministerial-fire(相火) as being in a position to hear the order from the 'heaven(天)' to control monarch-fire(君火). But the concept of ministerial-fire(相火) which he set connoted a confusing meaning of 'nature(性)' and 'way(道)' of Neo-Confucianism. In the later process to solve the problem, life-gate theory(命門學說) was raised, and many researchers had tried to remove the meaning of hyperactivity from the ministerial-fire(相火).

• 한국운동역학회지
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• 제16권3호
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• pp.117-124
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• 2006

The modern convenient life formed by industrial development becomes lack of exercise and takes an interest in diet. Specially, professional walking shoes is developed as people take an interest in jogging, Those shoes, professional walking shoes or Dietshoes, increase exercise effects by change of heel types. Therefore, this study investigated motility effects by EMG experiment in order to measure Muscle Activities (MA) while wearing diet shoes (backless). Experiment was conducted by EMG measurement, from calf (gastrocnemius muscle), thigh (vastus muscle) and waist (erector spinae muscle), of 12 high school students. Exercise effects between the two shoes were analyzed by EMG (MF; Median Frequency, MPF; Mean Power Frequency, ZCR; Zero Crossing Rate). Results showed that the Dietshoes(MF: 48.21Hz, MPF: 65.0Hz, ZCR: 100.6Hz) had larger EMG value than that of Normal shoes(MF: 40.47Hz, MPF: 58.04Hz, ZCR: 82.09Hz). Also, in MA, the highest activities are showed in the calf, the second one is in waist, and last one is in thigh during gate. ANOVA between shoes in measurement parts showed significant effects in MF (gastrocnemius: p-value=.022, vastus laterals: p-value=.037, erector spinae: p-value=.082), MPF (gastrocnemius: p-value=.032, vastus laterals: p-value=.046, erector spinae: p-value=.090), and ZCR (gastrocnemius: p-value=.000, vastus laterals: p-value=.004, erector spinae: p-value=.134). And MA of Dietshoes is higher than that of Normal shoes, and decreasing rate of MA in Dietshoes is less than that of Normal shoes. Thus, this study validates exercise effects of Dietshoes.

• 한국지능시스템학회논문지
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• 제11권5호
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• pp.426-432
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• 2001

본 논문은 진화형 하드웨어를 이용하여 생물의 정보처리 시스템인 셀룰라 오토마타 신경망의 구현에 관한 연구이다. 셀룰라 오토마타 신경망은 진화 및 발생을 기반으로 한 신경망 모델이다. 진화는 다양성을 주요 근원을 제공하는 돌연변이 및 재 조합 비율에 의하여 비결정론이며, 발생은 결정론 적이며 지역적인 무리현상을 따른다. 셀룰라 오토마타 신경망은 셀룰라 오토마타에 의해 신경망 내부의 각 셀의 상태를 발생시키고, 초기 셀을 유전자 알고리즘의 개체로 간주하여 초기 셀이 진화 알고리즘을 통해 진화함으로써 신경망이 진화하는 시스템이다. 본 논문은 이 시스템을 진화형 하드웨어 이용하여 하드웨어로 구현하였다. 진화형 하드웨어는 진화 알고리즘과 재구성하드웨어의 결합체이다. 즉, 재구성 하드웨어의 구성에 필요한 bit를 유전자 알고리즘의 개체로 간주한 것이다. 진화 알고리즘을 수행하기 위해 유전자 알고리즘 프로세서를 설계하였으며, 셀룰라 오토마타 신경망이 유전자 알고리즘의 개체와 셀룰라 오토마타 룰에 의해 자동적으로 신경망을 생성하기 위해 신경망을 이루는 셀들로 설계하였다. 제안된 시스템의 효율성을 검증하기 위해 Exclusive-OR 문제에 적용하였다.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 1992년도 추계학술대회 논문집
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• pp.123-127
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• 1992

MOS 커패시터가 이온화 방사선에 노출되었을 경우, MOS 커패시터의 방사선 조사 효과는 소자의 전기적 특성 및 동작 수명에 심각한 영향을 일으킬 수 있다. MOS 커패시터는 (100) 방향의 P-type Si wafer 위에 산화막층을 $O^2$+T.C.E. 분위기에서 성장하였으며, 그 두께는 40~80 nm로 만들었다. MOS 커패시터에 대한 방사선 조사는 $Co^{60}-{\gamma}$선을 사용하였고, 조사선량은 $10^4{\sim}10^8$으로 조사하였다. MOS 커패시터에서 전기적 전도 특성의 방사선 조사효과는 산화막 두께와 조사선량을 변화하면서 측정된 P-type MOS 커패시터는 조사선량에 의해서 강하게 영향을 받는다는 것과 저전계 영역에서의 Ohmic 전류가 전체 선량에 의존한다는 것을 알았다. 이 결과는 방사선 조사에 의해 산화막 트랩전하와 산화막-반도체($SiO_2$-Si)계면 트랩전하에 의해서 설명 할 수 있다.