• Title/Summary/Keyword: Life Time value

Search Result 1,321, Processing Time 0.028 seconds

Identification of Neuroactive Constituents of the Ethyl Acetate Fraction from Cyperi Rhizoma Using Bioactivity-Guided Fractionation

  • Sim, Yeomoon;Choi, Jin Gyu;Gu, Pil Sung;Ryu, Byeol;Kim, Jeong Hee;Kang, Insug;Jang, Dae Sik;Oh, Myung Sook
    • Biomolecules & Therapeutics
    • /
    • v.24 no.4
    • /
    • pp.438-445
    • /
    • 2016
  • Cyperi Rhizoma (CR), the rhizome of Cyperus rotundus L., exhibits neuroprotective effects in in vitro and in vivo models of neuronal diseases. Nevertheless, no study has aimed at finding the neuroactive constituent(s) of CR. In this study, we identified active compounds in a CR extract (CRE) using bioactivity-guided fractionation. We first compared the anti-oxidative and neuroprotective activities of four fractions and the CRE total extract. Only the ethyl acetate (EA) fraction revealed strong activity, and further isolation from the bioactive EA fraction yielded nine constituents: scirpusin A (1), scirpusin B (2), luteolin (3), 6'-acetyl-3,6-diferuloylsucrose (4), 4',6' diacetyl-3,6-diferuloylsucrose (5), p-coumaric acid (6), ferulic acid (7), pinellic acid (8), and fulgidic acid (9). The activities of constituents 1-9 were assessed in terms of anti-oxidative, neuroprotective, anti-inflammatory, and anti-amyloid-${\beta}$ activities. Constituents 1, 2, and 3 exhibited strong activities; constituents 1 and 2 were characterized for the first time in this study. These results provide evidence for the value of CRE as a source of multi-functional neuroprotectants, and constituents 1 and 2 may represent new candidates for further development in therapeutic use against neurodegenerative diseases.

Anti-wear performance and life evaluation of wheel bearing type greases

  • Kim Jung-Young;Chung Keun-Wo;Kim Young-Wun;Jo Won-Oh
    • Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
    • /
    • 2004.11a
    • /
    • pp.111-116
    • /
    • 2004
  • Li-complex and urea type greases (each 10 species) which were furnished by Chang-Am LS, analyzed anti-wear performance into fretting wear tester & four-bail wear tester. from the results of fretting wear test, the wear volume of Li-complex greases are $4.6\~8.9mg\;and\;8.3\~14.4mg$ with the test of urea greases. The anti-wear performance for 4-ball wear test of greases produced results around 0.5mm at the value of WSD. The grease life performance were evaluated by SKF-ROF Grease Tester and wheel bearing life tester. From the results of SKF-ROF tester, the life performance evaluated by whole working time produced results $50\~300hr$ with the Li-complex greases and 100-1000hr with the urea greases. That is to say, in spite of severe condition at the higher of $10^{\circ}C$ reaction temp, the life performance with Urea type greases are much superior to Li-complex type greases. Prior to wheel bearing life tester, the grease selected performance evaluation(=anti-wear test) are tested by wheel bearing tester. In this results, we can confirm results those are similar with SKF-ROF tester. In this study, we can draw two major conclusions, one is that Li-complex greases are superior to urea greases with anti-wear properties and the other is that urea greases are much superior to Li-complex greases with life performance.

  • PDF

The Greatest Senior Actor Jang Min-ho's Life on Acting (원로배우 장민호의 연기 인생)

  • Kim, Hyun-Hee
    • The Journal of the Korea Contents Association
    • /
    • v.15 no.5
    • /
    • pp.108-118
    • /
    • 2015
  • One hundred years have passed since the Western modern play emerged in Korea. Meanwhile, the numerous actors have appeared and disappeared as well, but leaving the record of their great art of acting is still negligible. For stage performances recorded and restoration of works of art creative process is a very important basis for future generations inherit a world of art. The aim of this study will look back on the life and achievements of the greatest senior actor, Jang Min-ho(1924-2012) died in 2012 and see his acting career and world of art. He was born at the time actors were not valued as an expert yet. Recording a life of an actor itself becomes an opportunity for fundamental reflection for the essence of play and role of actor, and introspecting an actor's life on acting becomes an effect that the actor's unique acting style is delivered to younger generations. By recording the actor's life and life on art, I hope that the contemporaries are able to recognize the value and importance of artists leading the contemporary era with being increased interest.

Humanistic Approach To Well-being (웰빙(Well-being)에 대한 인문학적 접근)

  • Cho, Yong-Ki;Kim, Seung-Nam
    • Journal of Korea Entertainment Industry Association
    • /
    • v.13 no.7
    • /
    • pp.321-346
    • /
    • 2019
  • The cycle of human life has a limited time to death. Everyone cannot help but think how to live in the limited time and then they try to reach toward their happiness. Their pursuit for the happiness gives rise to the new trend called 'Well-bing'. Generally speaking, it means to eat well, to feel their own satisfaction with their lives and to spend a time on doing what they want to do. However, considering their current lives which are tough and harsh, it could be impossible for them to accomplish the well-being stated above. From this point, it is natural to think what real well-being means. Its real meaning would be understood by identifying its cause if well-being is the way to happiness. Based on the thesis stated above, let me look into the desire of human being. It has both side; it should be eliminated or overcome as a deficiency and disability in human life while it could be an driving force to let the human being keep their lives. They can find the real meaning of well-being and their happiness can be realized through the control of their desires. Above all, according to the control for them, they can accomplish their happiness or fail to do it. The trend of well-being can be kept in our culture when moral value is reflected to the well-being. Finally, it orients to the purpose of happiness. It also means that everyone shares moral and positive value one another in the process of challenge to achieve their goals. In order to realize it, they should be satisfied with their current situation and have a balance with everything related to themselves.

Analysis of Generalized Extreme Value Distribution to Estimate Storm Sewer Capacity Under Climate Change (기후변화에 따른 하수관거시설의 계획우수량 산정을 위한 일반극치분포 분석)

  • Lee, Hak-Pyo;Ryu, Jae-Na;Yu, Soon-Yu;Park, Kyoo-Hong
    • Journal of Korean Society of Water and Wastewater
    • /
    • v.26 no.2
    • /
    • pp.321-329
    • /
    • 2012
  • In this study, statistical analysis under both stationary and non-stationary climate was conducted for rainfall data measured in Seoul. Generalised Extreme Value (GEV) distribution and Gumbel distribution were used for the analysis. Rainfall changes under the non-stationary climate were estimated by applying time variable (t) to location parameter (${\xi}$). Rainfall depths calculated in non-stationary climate increased by 1.1 to 6.2mm and 1.0 to 4.6mm for the GEV distribution and gumbel distribution respectively from those stationary forms. Changes in annual maximum rainfall were estimated with rate of change in the location parameter (${\xi}1{\cdot}t$), and temporal changes of return period were predicted. This was also available for re-evaluating the current sewer design return period. Design criteria of sewer system was newly suggested considering life expectance of the system as well as temporal changes in the return period.

Soundscapes of Soswaewon Represented in Kim In-Hu's 48 Poems (김인후의 48영에 표상된 소쇄원의 소리풍경)

  • Han, Myung-Ho;Cheon, Deuk-Youm
    • Journal of architectural history
    • /
    • v.24 no.6
    • /
    • pp.21-33
    • /
    • 2015
  • This study aims to rediscover the meaning and value of Soswaewon construction represented in Kim In-Hu's 48 poems on the basis of the concept and idea of soundscape. It classified the landscape resources through the various emotional elements such as the sense of sight, hearing, smell, touch, taste, and warmth described in the 48 poems of Soswaewon, and also interpreted the meaning and value of Soswaewon construction. Appreciating various sounds of Soswaewon, Kim In-Hu understood a sound as an important element of the landscape. Also, he abundantly wrote down the interesting changes of Soswaewon which vary depending on time or seasons. The 48 poems contain the scent and feel of Soswaewon as well as the soundscapes which can be heard with ears. A variety of sounds heard in Soswaewon are the whole senses which are combined with the chill of Soswaewon, the fragrance of trees and the mystery of the mountain, etc, and they mean the wider world much more than the value of physical sounds. Soundscapes of Soswaewon are becoming an emotional space which intactly conveys not only the musical inspiration but also the scent of life to us.

Shanghanlun Diagnostic System : Exploring Value as Narrative Medicine by Analyzing Cases (사례분석을 통한 『상한론(傷寒論)』 변병진단체계(辨病診斷體系)의 서사의학적 가치의 탐색)

  • Kim, Jin-A;Lee, Sung-Jun
    • 대한상한금궤의학회지
    • /
    • v.6 no.1
    • /
    • pp.1-25
    • /
    • 2014
  • Objective : The purpose of this study is exploring value of Shanghanlun six diagnostic system as Narrative Medicine by analyzing cases. Methods : In the article, we examined the theory of narrative medicine and current studies. And then key elements of narrative medicine was defined. On the basis of these, two medical cases were analyzed by reordering in accordance with time sequences and causality for confirming narrative factors. Results : The narrative approach to analyzing cases shows us that different diseases could be the result of same pathological patterns based on Shanghanlun. This tells us following four aspects. [1] Shanghanlun is the causes-oriented records and the text includes narrative factors. [2] Shanghanlun six diagnostic system is a process of constructing plot of medical case history through the clinical interpretation of contextual meaning of patient's life. [3] In the process of diagnosis, Schemata and script are engaged in assuming and confirming six patterns diseases. [4] The subjective factors of an individual can be applied universally through the provision of Shanghanlun. Conclusions : Narrative factors of Shanghanlun six diagnostic system suggest the possibility and value of Shanghan Medicine as Narrative Medicine in terms of Medical Humanities, essence of medical diagnosis and therapeutic action.

Analysing the effects of multi-channel strategy for CRM (고객관계관리에 있어서 다채널 전략의 효과 분석)

  • 전종근;주영혁;양석준
    • Journal of Distribution Research
    • /
    • v.9 no.2
    • /
    • pp.29-43
    • /
    • 2004
  • This research analyzed multi-channel strategy from the viewpoint of the customer relationship management. We hypothesized that the purchase frequency, monetary, purchase quantity of the existing customers should have increased after they used multiple channels of a company for shopping, All the hypothesis were supported in an empirical test using the customer database of a Korean TV home-shopping company, The result showed that the multi-channel strategy can be used to increase the life-time value of existing customers. Still there were a lot of customers who insists using traditional channel, which calls for a new strategy inducing them to use multi- channel for shopping.

  • PDF

Multidisciplinary Approach to Low Fertility Issue in Korea (저출산 대책에 대한 다학제적 접근)

  • Park, Jung Han
    • Health Policy and Management
    • /
    • v.28 no.3
    • /
    • pp.233-239
    • /
    • 2018
  • A rapid decrease of total fertility rate to 1.08 in 2005 prompted the Korean government to plan and implement a '5-year plan for ageing society and population policy' starting from 2006. The 1st and 2nd 5-year plans had not shown any discernible impact on the fertility and the 3rd 5-year plan was launched in 2016. However, the fertility rate is going down further. The author reviewed the contents and assessment reports of the fertility promotion plan to suggest ideas for complementing the shortcomings of it. Author defined the major determinants of marriage and child birth as philosophy, politics, sense of value, social norm, culture, healthcare, and education. The plan was examined in view of these determinants. Transformation of Korea from an agricultural society to an industrialized society in a short period of time had brought about changes in most of the determinants of marriage and child birth; in particular philosophy and sense of value. These aspects were not put into consideration in the plan. Author suggested to launch a social education program for the general public to establish a sound philosophy of life, reform the sense of value on family, child birth and education, and cultivate the skill to draw a consensus through discussions on the social issues. A special program to promote marriage of women at the optimum age for child birth was proposed. The government should implement well balanced policy for economic development and labor. Multidisciplinary approach was recommended for these tasks.

Effect of Several Exterior Adhesive Types on Dimensional Stability of Bamboo Oriented Particleboard

  • Iswanto, Apri Heri;Munthe, Rensus;Darwis, Atmawi;Azhar, Irawati;Susilowati, Arida;Prabuningrum, Dita Sari;Fatriasari, Widya
    • Korean Journal of Materials Research
    • /
    • v.29 no.5
    • /
    • pp.277-281
    • /
    • 2019
  • The objective of this research is to evaluate the effect of adhesive types on dimensional stability of bamboo-oriented particleboard. The materials used in this research are bamboo tali(Gigantochloa apus J.A & J.H. Schult. Kurz), UF/MDI(8, 10, 12 % level), and MF, MDI, and PF at 7 % level. Particle and adhesive are mixed using a blending machine; then, mat forming and hot pressing processes are performed using adhesive-suitable temperature and time references. MDI resin is set at $160^{\circ}C$ temperature for 5 minutes. PF resin and MF resin are pressed at $170^{\circ}C$ for 10 minutes, and $140^{\circ}C$ for 10 minutes, respectively, while UF/MDI sets at temperature of $140^{\circ}C$ for 10 minutes. The results show that particleboard using PF resin produces the lowest thickness swelling value. The particleboard using UF/MDI resin also produces good response for thickness swelling value. Interesting things happen in that UF/MDI adhesive produces a thickness swelling value better than that of MDI resin. FTIR analysis on particleboard bonded by UF/MDI resin combination shows the presence of carbonyl group C=O vibration on multi substitution of urea at wave number of around $1,700cm^{-1}$.