• Journal of the Korea institute for structural maintenance and inspection
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• v.6 no.4
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• pp.189-199
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• 2002

This study is intended to propose a systematic procedure for the development of the conditional assessment based on the safety of structures and the cost effective performance criteria for designing and upgrading of bridge structures. As a result, a set of cost function models for a life cycle cost analysis of bridge structures is proposed and thus the expected total life cycle costs (ETLCC) including initial (design, testing and construction) costs and direct/indirect damage costs considering repair and replacement costs, human losses and property damage costs, road user costs, and indirect regional economic losses costs. Also, the optimum safety indices are presented based on the expected total cost minimization function using only three parameters of the failure cost to the initial cost (${\tau}$), the extent of increased initial cost by improvement of safety (${\nu}$) and the order of an initial cost function (n). Through the enough numerical invetigations, we can positively conclude that the proposed optimum design procedure for bridge structures based on the ETLCC will lead to more rational, economical and safer design.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.50 no.9
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• pp.663-668
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• 2022

Since the early 2000s, the United States has applied TLCSM to reduce life cycle costs while maintaining the weapons system's combat readiness. With the application of TLCSM, the ILS concept centered on the acquisition stage shifted to IPS, a concept that manages life cycle costs throughout the entire life cycle. In addition, LSAR for developing ILS has switched to LPD for developing IPS. In this study, LSAR in Korea and LPD in the United States were compared and analyzed, and policies necessary for the introduction of LPD in Korea were proposed.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.13 no.1
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• pp.29-73
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• 1983

The age related changes in the life cycle of the progenitor cell population of murine oral epithelia was studied. Using radioautographic methods which have been adopted in previous cell cycle studies, the age-related changes of different phases in renewing cells of the palatal, buccal and lingual mucosae were determined. The results confirm published findings on cell cycle changes of epithelia with aging and illustrated further that mitotic phase which has hither to been considered stationary, also changes with aging. The major parts revealed by this study are as follows: 1) The basal progenitor cells in different regions of oral mucosa have different generation times. 2) The basal cell cycle time increases as a function of aging and the region most affected by aging appears to be the epithelium of the cheek. 3) The phases of the cell cycle affected by the process of aging are in increasing order of magnitude: M-, S- and G₁-phase. 4) The age elated change in the number of DNA synthesizing basal progenitor cells occurs at two age periods. Between 1 and 12 months of life it decreases, while from 12 to 20 months it increases.

• Journal of fish pathology
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• v.34 no.2
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• pp.177-184
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• 2021

Vaccines based on single-cycle viruses that are replication-incompetent due to knockout of replication-related structural gene(s) are more immunogenic than inactivated or subunit vaccines and can be used as delivery vehicles for foreign antigens without concerns on the reverting to virulent forms. The aim of this study was to develop a delivery vehicle for nervous necrosis virus (NNV)-like particles (VLPs) using G gene deleted single-cycle VHSV (rVHSV-𝚫G). Recombinant single-cycle VHSVs carrying NNV capsid protein gene between N and P gene of rVHSV-𝚫G genome (rVHSV-𝚫G-NNV_Cap) were rescued by reverse genetic technology. The successful expression of NNV capsid protein in cells infected with rVHSV-𝚫G-NNV_Cap was demonstrated by Western blot analysis, and the production of NNV VLPs in infected cells was confirmed using an electron microscopy. The results suggest that single-cycle VHSVs can be used as a safe delivery vehicle for NNV VLPs, and can be extended to other pathogens for the development of prophylactic vaccines.

• Journal of Convergence for Information Technology
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• v.11 no.10
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• pp.194-204
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• 2021

This study was conducted to find out the status and factors of private health insurance subscriptions by life cycle and to identify differences in medical usage behavior by life cycle. Using the SPSS 26 program as the 12th-15th (2016-2019) data of the Korea Welfare Panel, the difference subscriptions was identified as Chi-square by demo social and health characteristics of 58,223 people, and the factors affecting subscription were analyzed by polynomial logistic analysis and average analysis was performed for medical use behavior. As a result of the analysis, the biggest factor in purchasing private health insurance was household income, private health insurance coverage is the highest in growth period, and multiple subscriptions were made depending on household income. In youth, household income, spouse, and no disability, and middle age, household income, economic activities, spouses, and health levels were largely influential factors. The rate of private health insurance coverage in old age was the lowest, and low-income households, poor health levels, and people with disabilities were lower. The increase in medical use by private health insurance subscribers also occurred during growth and youth. It is necessary to strengthen the national health insurance coverage, and the role of private health insurance to supplement it should be established in time for the life cycle to complement each other, eliminating blind spots of medical security and maximizing people's health and well-being.

• Journal of the military operations research society of Korea
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• v.15 no.2
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• pp.147-159
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• 1989

This paper presents a formalized methodology for conducting cost-effectiveness analysis on the ROK Navy's maritime patrol aircraft. The methodology involves a Delphi method application for determining the group of appraisal variables as well as their weight values in the area of aircraft effectiveness analysis, Life-cycle costing was employed to produce cost in terms of present worth values of all costs that occur over the common 20-year life cycle. A wide range of experts was selected so that their opinions could be effectively collected and synthesized to form the framework of the effectiveness model. Such a model development strategy provides easy acceptance of the analysis result and assure fairness of the analysis.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.8 no.6
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• pp.2118-2138
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• 2014

Risks are involved in all phases of the software life cycle, and due to these risks, software can face various problems that can cause different negative outcomes and sometimes, in extreme cases, the failure of the software. Most of these risks lie in the legacy software migration process. These risks can create many problems, and in the worst case they can lead to the failure of the migration project. This paper explores different types of risk analysis methods such as CRAMM, CORAS, OCTAVE and VECTOR. After comparing these methods, the two suitable methods were chosen, namely, OCTAVE and VECTOR. Based on the use of these two methods, the project suggests an enhanced EOV method for risk analysis in the migration of legacy software.

• Proceedings of the KSR Conference
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• 2008.06a
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• pp.1350-1358
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• 2008

Recently the study related to life cycle cost analysis of railway structure consisted of a complex is proceeded covering several range, which is considering the methodology of efficiency and rationalization for maintenance and analysing long-time behavior of the structure of looking at standpoint from asset management and safety. But LCCA(life cycle cost analysis) of railway structure was almost impossible as there were not anything datum for maintenance plan, such as maintenance periods related to each of components(painting and corrosion of steel, and cracking of elements, etc)and maintenance proportion, despite of its 100-year history. According, for collecting data related to railway truss bridge, bridge record cards and testing safety papers, and researching question, etc are surveyed and classified for LCC Analysis. Especially, LCC assessment on the side of assets-maintenance considering about initial cost, maintenance cost, and indirect cost is constructed. Maintenance period and complementary measure rate are very important in maintenance. To decide maintenance period, Baysian updating method is applied.

• Journal of the Korea Institute of Building Construction
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• v.3 no.4
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• pp.129-134
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• 2003

The purpose of this study is to evaluate efficiency by the Life Cycle Cost(LCC) analysis of floor covering materials for remodeling. This study has been performed as a case study. The LCC analysis is a technique which takes account into both initial-future costs and benefits of an investment over some period of time. LCC is important in commercial decision making because it provides improved assessment of the living-term cost effectiveness of construction projects as well as alternative economic methods that focus on initial costs. For LCC analysis and comparison, the present value technique is used. The results of this study are summarized as follows; (1) A LCC analysis model of floor covering materials is suggested through a case study (2) As a result of LCC case study, the type of sheet is analysed more economical than that of tile in floor covering materials.

• Proceedings of the KSR Conference
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• 2008.11b
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• pp.1195-1203
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• 2008

In this study it is researched to the hazard analysis phase which is the core phase of the safety life cycle carried out by various systems in Korea. At present diverse methods are utilized when the hazard analysis is performed. With the basis of these V&V activities are carried out. In this study using FMEA which is one of the representative methods of the hazard analysis, the effective and viable result is derived. Also, it establishes the systematic base of the further phases of the safety life cycle such as the Hazard log, V&V, and the safety case.